Utrophin

"Utrophin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

An autosomally-encoded 376-kDa cytoskeletal protein that is similar in structure and function to DYSTROPHIN. It is a ubiquitously-expressed protein that plays a role in anchoring the CYTOSKELETON to the PLASMA MEMBRANE.

Descriptor ID

D049411

MeSH Number(s)

D12.776.220.987

D12.776.543.985

Concept/Terms

Utrophin

Below are MeSH descriptors whose meaning is more general than "Utrophin".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Cytoskeletal Proteins [D12.776.220]
Utrophin [D12.776.220.987]
Membrane Proteins [D12.776.543]
Utrophin [D12.776.543.985]

Below are MeSH descriptors whose meaning is related to "Utrophin".

Below are MeSH descriptors whose meaning is more specific than "Utrophin".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Utrophin" by people in Harvard Catalyst Profiles by year, and whether "Utrophin" was a major or minor topic of these publication.

Bar chart showing 12 publications over 9 distinct years, with a maximum of 2 publications in 1995 and 1997 and 2015

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	0	2	2
1997	0	2	2
1998	0	1	1
2001	0	1	1
2010	0	1	1
2011	1	0	1
2014	0	1	1
2015	0	2	2
2023	0	1	1

Below are the most recent publications written about "Utrophin" by people in Profiles.

Exercise-induced circular RNA circUtrn is required for cardiac physiological hypertrophy and prevents myocardial ischaemia-reperfusion injury. Cardiovasc Res. 2023 12 19; 119(16):2638-2652.

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Sarcospan increases laminin-binding capacity of a-dystroglycan to ameliorate DMD independent of Galgt2. Hum Mol Genet. 2022 03 03; 31(5):718-732.

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Effects of (-)-epicatechin on frontal cortex DAPC and dysbindin of the mdx mice. Neurosci Lett. 2017 Sep 29; 658:142-149.

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STX11 functions as a novel tumor suppressor gene in peripheral T-cell lymphomas. Cancer Sci. 2015 Oct; 106(10):1455-62.

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The Pathogenesis and Therapy of Muscular Dystrophies. Annu Rev Genomics Hum Genet. 2015; 16:281-308.

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Muscular dystrophy in a family of Labrador Retrievers with no muscle dystrophin and a mild phenotype. Neuromuscul Disord. 2015 May; 25(5):363-70.

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Whole body periodic acceleration is an effective therapy to ameliorate muscular dystrophy in mdx mice. PLoS One. 2014; 9(9):e106590.

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Cell entry of Lassa virus induces tyrosine phosphorylation of dystroglycan. Cell Microbiol. 2013 May; 15(5):689-700.

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Dystrophin and utrophin expression require sarcospan: loss of a7 integrin exacerbates a newly discovered muscle phenotype in sarcospan-null mice. Hum Mol Genet. 2012 Oct 15; 21(20):4378-93.

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Differential requirement for utrophin in the induced pluripotent stem cell correction of muscle versus fat in muscular dystrophy mice. PLoS One. 2011; 6(5):e20065.

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