Spherocytosis, Hereditary
"Spherocytosis, Hereditary" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A familial congenital hemolytic anemia characterized by numerous abnormally shaped erythrocytes which are generally spheroidal. The erythrocytes have increased osmotic fragility and are abnormally permeable to sodium ions.
MeSH Number(s)
C15.378.071.141.150.785
C16.320.070.785
Below are MeSH descriptors whose meaning is more general than "Spherocytosis, Hereditary".
- Diseases [C]
- Hemic and Lymphatic Diseases [C15]
- Hematologic Diseases [C15.378]
- Anemia [C15.378.071]
- Anemia, Hemolytic [C15.378.071.141]
- Anemia, Hemolytic, Congenital [C15.378.071.141.150]
- Spherocytosis, Hereditary [C15.378.071.141.150.785]
- Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
- Genetic Diseases, Inborn [C16.320]
- Anemia, Hemolytic, Congenital [C16.320.070]
- Spherocytosis, Hereditary [C16.320.070.785]
Below are MeSH descriptors whose meaning is more specific than "Spherocytosis, Hereditary".
This graph shows the total number of publications written about "Spherocytosis, Hereditary" by people in Harvard Catalyst Profiles by year, and whether "Spherocytosis, Hereditary" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
| 1995 | 3 | 1 | 4 |
| 1996 | 4 | 2 | 6 |
| 1997 | 2 | 0 | 2 |
| 1998 | 0 | 1 | 1 |
| 1999 | 1 | 1 | 2 |
| 2000 | 1 | 0 | 1 |
| 2001 | 0 | 1 | 1 |
| 2003 | 2 | 0 | 2 |
| 2004 | 1 | 1 | 2 |
| 2005 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2011 | 2 | 0 | 2 |
| 2014 | 2 | 0 | 2 |
| 2015 | 2 | 0 | 2 |
| 2019 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
| 2022 | 2 | 0 | 2 |
| 2023 | 1 | 0 | 1 |
Below are the most recent publications written about "Spherocytosis, Hereditary" by people in Profiles.
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Mitapivat reprograms the RBC metabolome and improves anemia in a mouse model of hereditary spherocytosis. JCI Insight. 2023 Oct 23; 8(20).
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Platelets: out of shape and misbehaving. Blood. 2022 11 24; 140(21):2188-2190.
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Glucose 6 Phosphate Isomerase Deficiency, a Rare Hemolytic Anemia Misdiagnosed as Hereditary Spherocytosis. J Pediatr Hematol Oncol. 2023 01 01; 45(1):41-43.
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A Grammastola spatulata mechanotoxin-4 (GsMTx4)-sensitive cation channel mediates increased cation permeability in human hereditary spherocytosis of multiple genetic etiologies. Haematologica. 2021 10 01; 106(10):2759-2762.
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Clinical and laboratory outcomes following total or partial splenectomy in patients with hereditary spherocytosis. Pediatr Hematol Oncol. 2019 Sep; 36(6):382-389.
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Fatal Cardiac Hemochromatosis in a Patient with Hereditary Spherocytosis. Int Heart J. 2018 Mar 30; 59(2):427-430.
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Hematologic outcomes after total splenectomy and partial splenectomy for congenital hemolytic anemia. J Pediatr Surg. 2016 Jan; 51(1):122-7.
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High-density genomic analysis reveals basis of spherocytosis in myelodysplastic syndrome. Blood. 2015 May 28; 125(22):3517.
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Clinical outcomes of splenectomy in children: report of the splenectomy in congenital hemolytic anemia registry. Am J Hematol. 2015 Mar; 90(3):187-92.
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The use of erythropoietin-stimulating agents versus supportive care in newborns with hereditary spherocytosis: a single centre's experience. Eur J Haematol. 2014 Aug; 93(2):161-4.