Anion Exchange Protein 1, Erythrocyte
"Anion Exchange Protein 1, Erythrocyte" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ubiquitous membrane transport protein found in the plasma membrane of diverse cell types and tissues, and in nuclear, mitochondrial, and Golgi membranes. It is the major integral transmembrane protein of the erythrocyte plasma membrane, comprising 25% of the total membrane protein. It exists as a dimer and performs the important function of allowing the efficient transport of bicarbonate across erythrocyte cell membranes in exchange for chloride ion.
MeSH Number(s)
D12.776.124.078
D12.776.157.530.450.162.110
D12.776.157.530.450.162.193.500
D12.776.543.550.190.110
D12.776.543.550.190.276.500
D12.776.543.585.450.162.110
D12.776.543.585.450.162.193.500
Concept/Terms
Anion Exchange Protein 1, Erythrocyte- Anion Exchange Protein 1, Erythrocyte
- AE1 Gene Product
- Protein Band 3
- Band 3 Protein
- Protein, Band 3
- Band III Protein
- Protein, Band III
- AE1 Anion Exchanger
- Erythrocyte Anion Transport Protein
- Anion Transport Protein, Erythrocyte
- Erythrocyte Membrane Band 3 Protein
- Erythrocyte Anion Exchanger
- Anion Exchanger, Erythrocyte
- Erythrocyte Membrane Anion Transport Protein
- AE1 Cl- HCO3- Exchanger
- AE1 Cl HCO3 Exchanger
- AE1 Chloride-Bicarbonate Exchanger
- AE1 Chloride Bicarbonate Exchanger
- Chloride-Bicarbonate Exchanger, AE1
- Capnophorin
Below are MeSH descriptors whose meaning is more general than "Anion Exchange Protein 1, Erythrocyte".
Below are MeSH descriptors whose meaning is more specific than "Anion Exchange Protein 1, Erythrocyte".
This graph shows the total number of publications written about "Anion Exchange Protein 1, Erythrocyte" by people in Harvard Catalyst Profiles by year, and whether "Anion Exchange Protein 1, Erythrocyte" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 6 | 1 | 7 |
| 1995 | 4 | 0 | 4 |
| 1996 | 4 | 1 | 5 |
| 1997 | 4 | 0 | 4 |
| 1998 | 6 | 1 | 7 |
| 1999 | 1 | 3 | 4 |
| 2000 | 0 | 1 | 1 |
| 2002 | 0 | 3 | 3 |
| 2003 | 4 | 0 | 4 |
| 2004 | 3 | 0 | 3 |
| 2005 | 1 | 0 | 1 |
| 2007 | 5 | 2 | 7 |
| 2008 | 2 | 0 | 2 |
| 2009 | 1 | 1 | 2 |
| 2010 | 3 | 1 | 4 |
| 2011 | 2 | 1 | 3 |
| 2012 | 2 | 0 | 2 |
| 2013 | 1 | 1 | 2 |
| 2016 | 1 | 2 | 3 |
| 2017 | 0 | 1 | 1 |
| 2018 | 1 | 1 | 2 |
| 2019 | 0 | 1 | 1 |
| 2020 | 2 | 0 | 2 |
| 2022 | 0 | 1 | 1 |
Below are the most recent publications written about "Anion Exchange Protein 1, Erythrocyte" by people in Profiles.
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Hereditary anemia caused by multilocus inheritance of PIEZO1, SLC4A1 and ABCB6 mutations: a diagnostic and therapeutic challenge. Haematologica. 2022 09 01; 107(9):2280-2284.
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Genome-Wide Association for HbA1c in Malay Identified Deletion on SLC4A1 that Influences HbA1c Independent of Glycemia. J Clin Endocrinol Metab. 2020 12 01; 105(12).
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A different clinical manifestation in a Japanese family with autosomal dominant distal renal tubular acidosis caused by SLC4A1 mutation. CEN Case Rep. 2020 11; 9(4):442-445.
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Band 3 ectopic expression in colorectal cancer induces an increase in erythrocyte membrane-bound IgG and may cause immune-related anemia. Int J Hematol. 2020 May; 111(5):657-666.
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Whole exome sequencing identified ATP6V1C2 as a novel candidate gene for recessive distal renal tubular acidosis. Kidney Int. 2020 03; 97(3):567-579.
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Genotype-Phenotype Analysis in Pediatric Patients with Distal Renal Tubular Acidosis. Kidney Blood Press Res. 2018; 43(2):513-521.
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Targeted deletion of the Ncoa7 gene results in incomplete distal renal tubular acidosis in mice. Am J Physiol Renal Physiol. 2018 07 01; 315(1):F173-F185.
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Transcriptomes of major renal collecting duct cell types in mouse identified by single-cell RNA-seq. Proc Natl Acad Sci U S A. 2017 11 14; 114(46):E9989-E9998.
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Intercalated Cell Depletion and Vacuolar H+-ATPase Mistargeting in an Ae1 R607H Knockin Model. J Am Soc Nephrol. 2017 May; 28(5):1507-1520.
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A single nucleotide polymorphism in kidney anion exchanger 1 gene is associated with incomplete type 1 renal tubular acidosis. Sci Rep. 2016 10 21; 6:35841.