Harvard Catalyst Profiles

An experimental animal model for the demyelinating disease of GUILLAINE-BARRE SYNDROME. In the most frequently used protocol, animals are injected with a peripheral nerve tissue protein homogenate. After approximately 2 weeks the animals develop a neuropathy secondary to a T cell-mediated autoimmune response directed towards the MYELIN P2 PROTEIN in peripheral nerves. Pathologic findings include a perivascular accumulation of macrophages and T lymphocytes in the peripheral nervous system, similar to that seen in the Guillaine-Barre syndrome. (From Adams et al., Principles of Neurology, 6th ed, p1314; J Neuroimmunol 1998 Apr 1;84(1):40-52)

Below are MeSH descriptors whose meaning is more general than "Neuritis, Autoimmune, Experimental".

Below are MeSH descriptors whose meaning is related to "Neuritis, Autoimmune, Experimental".

Below are MeSH descriptors whose meaning is more specific than "Neuritis, Autoimmune, Experimental".