Deoxyribonucleases, Type I Site-Specific
"Deoxyribonucleases, Type I Site-Specific" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzyme systems containing three different subunits and requiring ATP, S-adenosylmethionine, and magnesium for endonucleolytic activity to give random double-stranded fragments with terminal 5'-phosphates. They function also as DNA-dependent ATPases and modification methylases, catalyzing the reactions of EC 2.1.1.72 and EC 2.1.1.73 with similar site-specificity. The systems recognize specific short DNA sequences and cleave at sites remote from the recognition sequence. Enzymes from different microorganisms with the same specificity are called isoschizomers. EC 3.1.21.3.
MeSH Number(s)
D08.811.150.280.250
D08.811.277.352.335.350.300.250
D08.811.277.352.355.325.300.250
Concept/Terms
Deoxyribonucleases, Type I Site-Specific- Deoxyribonucleases, Type I Site-Specific
- Deoxyribonucleases, Type I Site Specific
- Deoxyribonucleases, Type I, Site-Specific
- Type I Site Specific Deoxyribonucleases
- Type I Site-Specific Deoxyribonucleases
- DNA Restriction Enzymes, Type I
- Type I Restriction Enzymes
- Site-Specific DNase, Type I
- Site Specific DNase, Type I
- Type I Site Specific DNase
- Type I Site-Specific DNase
- DNase, Site-Specific, Type I
- Restriction Endonucleases, Type I
- Deoxyribonucleases, Type I, Site Specific
- DNase, Site Specific, Type I
Below are MeSH descriptors whose meaning is more general than "Deoxyribonucleases, Type I Site-Specific".
Below are MeSH descriptors whose meaning is more specific than "Deoxyribonucleases, Type I Site-Specific".
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Below are the most recent publications written about "Deoxyribonucleases, Type I Site-Specific" by people in Profiles.
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Crystal structure of I-DmoI in complex with its target DNA provides new insights into meganuclease engineering. Proc Natl Acad Sci U S A. 2008 Nov 04; 105(44):16888-93.