Receptors, Leukotriene B4
"Receptors, Leukotriene B4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of cell surface leukotriene receptors with a preference for leukotriene B4. Leukotriene B4 receptor activation influences chemotaxis, chemokinesis, adherence, enzyme release, oxidative bursts, and degranulation in polymorphonuclear leukocytes. There are at least two subtypes of these receptors. Some actions are mediated through the inositol phosphate and diacylglycerol second messenger systems.
MeSH Number(s)
D12.776.543.750.075.450.300
D12.776.543.750.100.200.450.300
Concept/Terms
Receptors, Leukotriene B4- Receptors, Leukotriene B4
- Leukotriene B4 Receptors
- LTB4 Receptors
- Receptors, LTB4
- LTB4 Receptor
- Receptor, LTB4
- Leukotriene B4 Receptor
- Receptor, Leukotriene B4
Below are MeSH descriptors whose meaning is more general than "Receptors, Leukotriene B4".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Eicosanoid [D12.776.543.750.075]
- Receptors, Leukotriene [D12.776.543.750.075.450]
- Receptors, Leukotriene B4 [D12.776.543.750.075.450.300]
- Receptors, G-Protein-Coupled [D12.776.543.750.100]
- Receptors, Eicosanoid [D12.776.543.750.100.200]
- Receptors, Leukotriene [D12.776.543.750.100.200.450]
- Receptors, Leukotriene B4 [D12.776.543.750.100.200.450.300]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Leukotriene B4".
This graph shows the total number of publications written about "Receptors, Leukotriene B4" by people in Harvard Catalyst Profiles by year, and whether "Receptors, Leukotriene B4" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 1 | 2 |
| 1999 | 2 | 1 | 3 |
| 2000 | 2 | 3 | 5 |
| 2001 | 0 | 2 | 2 |
| 2002 | 0 | 1 | 1 |
| 2003 | 4 | 0 | 4 |
| 2004 | 0 | 1 | 1 |
| 2005 | 5 | 0 | 5 |
| 2006 | 2 | 0 | 2 |
| 2007 | 2 | 1 | 3 |
| 2010 | 1 | 0 | 1 |
| 2011 | 1 | 1 | 2 |
| 2012 | 0 | 3 | 3 |
| 2013 | 0 | 3 | 3 |
| 2014 | 1 | 1 | 2 |
| 2015 | 0 | 1 | 1 |
| 2016 | 3 | 0 | 3 |
| 2017 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
Below are the most recent publications written about "Receptors, Leukotriene B4" by people in Profiles.
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Soluble epoxide hydrolase inhibition enhances production of specialized pro-resolving lipid mediator and promotes macrophage plasticity. Br J Pharmacol. 2023 06; 180(12):1597-1615.
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Isoflurane attenuates sepsis-associated lung injury. Biochem Biophys Res Commun. 2022 04 09; 599:127-133.
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Leukotriene B4 promotes neovascularization and macrophage recruitment in murine wet-type AMD models. JCI Insight. 2018 09 20; 3(18).
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Stepwise phosphorylation of leukotriene B4 receptor 1 defines cellular responses to leukotriene B4. Sci Signal. 2018 08 21; 11(544).
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LTB4 and BLT1 in inflammatory arthritis. Semin Immunol. 2017 10; 33:52-57.
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Neutrophil Resolvin E1 Receptor Expression and Function in Type 2 Diabetes. J Immunol. 2017 01 15; 198(2):718-728.
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Critical Role of LTB4/BLT1 in IL-23-Induced Synovial Inflammation and Osteoclastogenesis via NF-?B. J Immunol. 2017 01 01; 198(1):452-460.
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Chemoattractant Receptors BLT1 and CXCR3 Regulate Antitumor Immunity by Facilitating CD8+ T Cell Migration into Tumors. J Immunol. 2016 09 01; 197(5):2016-26.
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Crystalline silica-induced leukotriene B4-dependent inflammation promotes lung tumour growth. Nat Commun. 2015 Apr 29; 6:7064.
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Distinct cellular sources of hepoxilin A3 and leukotriene B4 are used to coordinate bacterial-induced neutrophil transepithelial migration. J Immunol. 2015 Feb 01; 194(3):1304-15.