Poly(A)-Binding Proteins

"Poly(A)-Binding Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Proteins that bind to the 3' polyadenylated region of MRNA. When complexed with RNA the proteins serve an array of functions such as stabilizing the 3' end of RNA, promoting poly(A) synthesis and stimulating mRNA translation.

Descriptor ID

D039102

MeSH Number(s)

D12.776.157.725.452

D12.776.664.962.452

Concept/Terms

Poly(A)-Binding Proteins

Below are MeSH descriptors whose meaning is more general than "Poly(A)-Binding Proteins".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Carrier Proteins [D12.776.157]
RNA-Binding Proteins [D12.776.157.725]
Poly(A)-Binding Proteins [D12.776.157.725.452]
Nucleoproteins [D12.776.664]
RNA-Binding Proteins [D12.776.664.962]
Poly(A)-Binding Proteins [D12.776.664.962.452]

Below are MeSH descriptors whose meaning is related to "Poly(A)-Binding Proteins".

Below are MeSH descriptors whose meaning is more specific than "Poly(A)-Binding Proteins".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Poly(A)-Binding Proteins" by people in Harvard Catalyst Profiles by year, and whether "Poly(A)-Binding Proteins" was a major or minor topic of these publication.

Bar chart showing 25 publications over 20 distinct years, with a maximum of 2 publications in 2000 and 2002 and 2003 and 2007 and 2009

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	0	1	1
1996	0	1	1
1997	0	1	1
1999	0	1	1
2000	0	2	2
2001	1	0	1
2002	0	2	2
2003	0	2	2
2004	0	1	1
2005	1	0	1
2006	0	1	1
2007	1	1	2
2008	0	1	1
2009	1	1	2
2011	1	0	1
2013	1	0	1
2016	0	1	1
2017	1	0	1
2018	1	0	1
2019	1	0	1

Below are the most recent publications written about "Poly(A)-Binding Proteins" by people in Profiles.

Inferring protein 3D structure from deep mutation scans. Nat Genet. 2019 07; 51(7):1170-1176.

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Extensive Structural Differences of Closely Related 3' mRNA Isoforms: Links to Pab1 Binding and mRNA Stability. Mol Cell. 2018 12 06; 72(5):849-861.e6.

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Protein 4.1R Exon 16 3' Splice Site Activation Requires Coordination among TIA1, Pcbp1, and RBM39 during Terminal Erythropoiesis. Mol Cell Biol. 2017 05 01; 37(9).

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Global hypermethylation in fetal cortex of Down syndrome due to DNMT3L overexpression. Hum Mol Genet. 2016 05 01; 25(9):1714-27.

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Phenotypic evolution in a case of peripheral T-cell lymphoma suggests the presence of tumor heterogeneity. J Cutan Pathol. 2013 Jun; 40(6):573-9.

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The fate of the messenger is pre-determined: a new model for regulation of gene expression. Biochim Biophys Acta. 2013 Jun-Jul; 1829(6-7):643-53.

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Alternative translation initiation augments the human mitochondrial proteome. Nucleic Acids Res. 2013 Feb 01; 41(4):2354-69.

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Nanopore detachment kinetics of poly(A) binding proteins from RNA molecules reveals the critical role of C-terminus interactions. Biophys J. 2012 Mar 21; 102(6):1427-34.

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Stress puts TIA on TOP. Genes Dev. 2011 Oct 15; 25(20):2119-24.

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Muscular involvement assessed by MRI correlates to motor function measurement values in oculopharyngeal muscular dystrophy. J Neurol. 2011 Jul; 258(7):1333-40.

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