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Polypyrimidine Tract-Binding Protein

"Polypyrimidine Tract-Binding Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

A RNA-binding protein that binds to polypyriminidine rich regions in the INTRONS of messenger RNAs. Polypyrimidine tract-binding protein may be involved in regulating the ALTERNATIVE SPLICING of mRNAs since its presence on an intronic RNA region that is upstream of an EXON inhibits the splicing of the exon into the final mRNA product.


This graph shows the total number of publications written about "Polypyrimidine Tract-Binding Protein" by people in Harvard Catalyst Profiles by year, and whether "Polypyrimidine Tract-Binding Protein" was a major or minor topic of these publication.
Bar chart showing 21 publications over 16 distinct years, with a maximum of 3 publications in 2014 and 2018
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.