Acyl-CoA Dehydrogenase, Long-Chain
"Acyl-CoA Dehydrogenase, Long-Chain" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A flavoprotein oxidoreductase that has specificity for long-chain fatty acids. It forms a complex with ELECTRON-TRANSFERRING FLAVOPROTEINS and conveys reducing equivalents to UBIQUINONE.
MeSH Number(s)
D08.811.682.660.150.150
D12.776.331.102
Concept/Terms
Acyl-CoA Dehydrogenase, Long-Chain- Acyl-CoA Dehydrogenase, Long-Chain
- Acyl CoA Dehydrogenase, Long Chain
- Dehydrogenase, Long-Chain Acyl-CoA
- Long-Chain Acyl-CoA Dehydrogenase
- Very-Long-Chain Acyl-CoA Dehydrogenase
- Acyl-CoA Dehydrogenase, Very-Long-Chain
- Dehydrogenase, Very-Long-Chain Acyl-CoA
- Very Long Chain Acyl CoA Dehydrogenase
- Long-Chain-Acyl-Coenzyme A Dehydrogenase
- Dehydrogenase, Long-Chain-Acyl-Coenzyme A
- Long Chain Acyl Coenzyme A Dehydrogenase
- Long-Chain-Acyl-CoA Dehydrogenase
- Dehydrogenase, Long-Chain-Acyl-CoA
- Long Chain Acyl CoA Dehydrogenase
- VLCAD
Decanoyl CoA Dehydrogenase- Decanoyl CoA Dehydrogenase
- CoA Dehydrogenase, Decanoyl
- Dehydrogenase, Decanoyl CoA
- Decanoyl CoA-Dehydrogenase
- CoA-Dehydrogenase, Decanoyl
Below are MeSH descriptors whose meaning is more general than "Acyl-CoA Dehydrogenase, Long-Chain".
Below are MeSH descriptors whose meaning is more specific than "Acyl-CoA Dehydrogenase, Long-Chain".
This graph shows the total number of publications written about "Acyl-CoA Dehydrogenase, Long-Chain" by people in Harvard Catalyst Profiles by year, and whether "Acyl-CoA Dehydrogenase, Long-Chain" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 2 | 3 |
| 1999 | 1 | 0 | 1 |
| 2000 | 1 | 1 | 2 |
| 2001 | 1 | 0 | 1 |
| 2002 | 0 | 2 | 2 |
| 2005 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2010 | 3 | 0 | 3 |
| 2013 | 1 | 1 | 2 |
| 2014 | 2 | 0 | 2 |
| 2015 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 2 | 1 | 3 |
| 2021 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
Below are the most recent publications written about "Acyl-CoA Dehydrogenase, Long-Chain" by people in Profiles.
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Structural basis for defective membrane targeting of mutant enzyme in human VLCAD deficiency. Nat Commun. 2022 06 27; 13(1):3669.
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Mitochondrial morphology, bioenergetics and proteomic responses in fatty acid oxidation disorders. Redox Biol. 2021 05; 41:101923.
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Impact of newborn screening on the reported incidence and clinical outcomes associated with medium- and long-chain fatty acid oxidation disorders. Genet Med. 2021 05; 23(5):816-829.
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Delayed Onset of Retinopathy of Prematurity Associated With Mitochondrial Dysfunction and Pearson Syndrome. J Pediatr Ophthalmol Strabismus. 2019 Oct 17; 56:e60-e64.
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Increased ketone body oxidation provides additional energy for the failing heart without improving cardiac efficiency. Cardiovasc Res. 2019 09 01; 115(11):1606-1616.
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Hypotonia and Lethargy in a Two-Day-Old Male Infant. Pediatrics. 2019 07; 144(1).
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Dynamic Regulation of Long-Chain Fatty Acid Oxidation by a Noncanonical Interaction between the MCL-1 BH3 Helix and VLCAD. Mol Cell. 2018 03 01; 69(5):729-743.e7.
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Long-term outcome of expanded newborn screening at Boston children's hospital: benefits and challenges in defining true disease. J Inherit Metab Dis. 2017 03; 40(2):209-218.
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Strategies for correcting very long chain acyl-CoA dehydrogenase deficiency. J Biol Chem. 2015 Apr 17; 290(16):10486-94.
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Dosage changes of a segment at 17p13.1 lead to intellectual disability and microcephaly as a result of complex genetic interaction of multiple genes. Am J Hum Genet. 2014 Nov 06; 95(5):565-78.