P-Glycoprotein

"P-Glycoprotein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A 170-kDa transmembrane glycoprotein from the superfamily of ATP-BINDING CASSETTE TRANSPORTERS. It serves as an ATP-dependent efflux pump for a variety of chemicals, including many ANTINEOPLASTIC AGENTS. Overexpression of this glycoprotein is associated with multidrug resistance (see DRUG RESISTANCE, MULTIPLE).

Descriptor ID

D020168

MeSH Number(s)

D12.776.157.530.100.652.500

D12.776.157.530.450.074.500.500.750

D12.776.395.550.020.610.610

D12.776.543.550.192.610.610

D12.776.543.585.100.610.500

D12.776.543.585.450.074.500.500.750

Concept/Terms

P-Glycoprotein

Below are MeSH descriptors whose meaning is more general than "P-Glycoprotein".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Carrier Proteins [D12.776.157]
Membrane Transport Proteins [D12.776.157.530]
ATP-Binding Cassette Transporters [D12.776.157.530.100]
P-Glycoproteins [D12.776.157.530.100.652]
P-Glycoprotein [D12.776.157.530.100.652.500]
Ion Pumps [D12.776.157.530.450]
Anion Transport Proteins [D12.776.157.530.450.074]
Organic Anion Transporters [D12.776.157.530.450.074.500]
Organic Anion Transporters, ATP-Dependent [D12.776.157.530.450.074.500.500]
P-Glycoprotein [D12.776.157.530.450.074.500.500.750]
Glycoproteins [D12.776.395]
Membrane Glycoproteins [D12.776.395.550]
ATP-Binding Cassette Transporters [D12.776.395.550.020]
P-Glycoproteins [D12.776.395.550.020.610]
P-Glycoprotein [D12.776.395.550.020.610.610]
Membrane Proteins [D12.776.543]
Membrane Glycoproteins [D12.776.543.550]
ATP-Binding Cassette Transporters [D12.776.543.550.192]
P-Glycoproteins [D12.776.543.550.192.610]
P-Glycoprotein [D12.776.543.550.192.610.610]
Membrane Transport Proteins [D12.776.543.585]
ATP-Binding Cassette Transporters [D12.776.543.585.100]
P-Glycoproteins [D12.776.543.585.100.610]
P-Glycoprotein [D12.776.543.585.100.610.500]
Ion Pumps [D12.776.543.585.450]
Anion Transport Proteins [D12.776.543.585.450.074]
Organic Anion Transporters [D12.776.543.585.450.074.500]
Organic Anion Transporters, ATP-Dependent [D12.776.543.585.450.074.500.500]
P-Glycoprotein [D12.776.543.585.450.074.500.500.750]

Below are MeSH descriptors whose meaning is related to "P-Glycoprotein".

Below are MeSH descriptors whose meaning is more specific than "P-Glycoprotein".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "P-Glycoprotein" by people in Harvard Catalyst Profiles by year, and whether "P-Glycoprotein" was a major or minor topic of these publication.

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