Receptors, Serotonin, 5-HT3
"Receptors, Serotonin, 5-HT3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subclass of serotonin receptors that form cation channels and mediate signal transduction by depolarizing the cell membrane. The cation channels are formed from 5 receptor subunits. When stimulated the receptors allow the selective passage of SODIUM; POTASSIUM; and CALCIUM.
MeSH Number(s)
D12.776.157.530.400.400.100.700
D12.776.543.550.425.500.100.700
D12.776.543.585.400.500.100.700
D12.776.543.750.051.750
D12.776.543.750.070.800.300
D12.776.543.750.720.300.800.300
Concept/Terms
Receptors, Serotonin, 5-HT3- Receptors, Serotonin, 5-HT3
- Serotonin 3 Receptors
- Receptors, Serotonin 3
- Receptor, Serotonin 3
- Serotonin 3 Receptor
- 5-HT3 Receptor
- 5 HT3 Receptor
- 5-Hydroxytryptamine-3 Receptor
- 5 Hydroxytryptamine 3 Receptor
- Receptor, 5-Hydroxytryptamine-3
Below are MeSH descriptors whose meaning is more general than "Receptors, Serotonin, 5-HT3".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Carrier Proteins [D12.776.157]
- Membrane Transport Proteins [D12.776.157.530]
- Ion Channels [D12.776.157.530.400]
- Ligand-Gated Ion Channels [D12.776.157.530.400.400]
- Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.157.530.400.400.100]
- Receptors, Serotonin, 5-HT3 [D12.776.157.530.400.400.100.700]
- Membrane Proteins [D12.776.543]
- Membrane Glycoproteins [D12.776.543.550]
- Ion Channels [D12.776.543.550.425]
- Ligand-Gated Ion Channels [D12.776.543.550.425.500]
- Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.543.550.425.500.100]
- Receptors, Serotonin, 5-HT3 [D12.776.543.550.425.500.100.700]
- Membrane Transport Proteins [D12.776.543.585]
- Ion Channels [D12.776.543.585.400]
- Ligand-Gated Ion Channels [D12.776.543.585.400.500]
- Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.543.585.400.500.100]
- Receptors, Serotonin, 5-HT3 [D12.776.543.585.400.500.100.700]
- Receptors, Cell Surface [D12.776.543.750]
- Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.543.750.051]
- Receptors, Serotonin, 5-HT3 [D12.776.543.750.051.750]
- Receptors, Biogenic Amine [D12.776.543.750.070]
- Receptors, Serotonin [D12.776.543.750.070.800]
- Receptors, Serotonin, 5-HT3 [D12.776.543.750.070.800.300]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Biogenic Amine [D12.776.543.750.720.300]
- Receptors, Serotonin [D12.776.543.750.720.300.800]
- Receptors, Serotonin, 5-HT3 [D12.776.543.750.720.300.800.300]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Serotonin, 5-HT3".
This graph shows the total number of publications written about "Receptors, Serotonin, 5-HT3" by people in Harvard Catalyst Profiles by year, and whether "Receptors, Serotonin, 5-HT3" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 2 | 2 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2005 | 3 | 0 | 3 |
| 2007 | 2 | 1 | 3 |
| 2008 | 0 | 2 | 2 |
| 2009 | 1 | 0 | 1 |
| 2010 | 2 | 1 | 3 |
| 2013 | 1 | 1 | 2 |
| 2015 | 1 | 2 | 3 |
| 2016 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 0 | 2 | 2 |
| 2019 | 2 | 1 | 3 |
Below are the most recent publications written about "Receptors, Serotonin, 5-HT3" by people in Profiles.
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Prenatal intermittent hypoxia sensitizes the laryngeal chemoreflex, blocks serotoninergic shortening of the reflex, and reduces 5-HT3 receptor binding in the NTS in anesthetized rat pups. Exp Neurol. 2020 04; 326:113166.
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Single-cell RNA-Seq characterization of anatomically identified OLM interneurons in different transgenic mouse lines. Eur J Neurosci. 2019 12; 50(11):3750-3771.
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Molecular mechanism of setron-mediated inhibition of full-length 5-HT3A receptor. Nat Commun. 2019 07 19; 10(1):3225.
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Thermal A-d Nociceptors, Identified by Transcriptomics, Express Higher Levels of Anesthesia-Sensitive Receptors Than Thermal C-Fibers and Are More Suppressible by Low-Dose Isoflurane. Anesth Analg. 2018 07; 127(1):263-266.
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Layer I Interneurons Sharpen Sensory Maps during Neonatal Development. Neuron. 2018 07 11; 99(1):98-116.e7.
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Distinct Functional Groups Emerge from the Intrinsic Properties of Molecularly Identified Entorhinal Interneurons and Principal Cells. Cereb Cortex. 2017 06 01; 27(6):3186-3207.
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Serotonergic agents act on 5-HT3 receptors in the brain to block seizure-induced respiratory arrest in the DBA/1 mouse model of SUDEP. Epilepsy Behav. 2016 11; 64(Pt A):166-170.
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Regulation of systemic energy homeostasis by serotonin in adipose tissues. Nat Commun. 2015 Apr 13; 6:6794.
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5-HT3 receptors antagonists reduce serotonin-induced scratching in mice. Fundam Clin Pharmacol. 2015 Jun; 29(3):310-5.
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Sensory inputs control the integration of neurogliaform interneurons into cortical circuits. Nat Neurosci. 2015 Mar; 18(3):393-401.