Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Raina Nakova Fichorova, Ph.D., M.D.

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Mentoring
completed student projects
Vaginal Microbiome-Host Interactions
Full Time/Year Long, 10/01/15 - 10/31/16

Research
research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
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  1. R01HD099091 (FICHOROVA, RAINA N.) May 13, 2019 - Mar 31, 2024
    NIH/NICHD
    MicroRNA Predictors of HIV Risk in Reproductive Age Women
    Role: Principal Investigator
  2. R01HD092374 (O'SHEA, MICHAEL) Sep 8, 2017 - May 31, 2022
    NIH
    Placental Epigenome and Brain Dysfunction after Preterm Birth
    Role: Co-Investigator
  3. R01MH100125 (BURDICK, KATHERINE ELIZABETH) Aug 1, 2017 - Apr 30, 2018
    NIH/NIMH
    Understanding the neurocognitive heterogeneity in bipolar disorder
    Role: Co-Investigator
  4. UH3OD023285 (PANETH, NIGEL SEFTON) Sep 21, 2016 - Aug 31, 2023
    NIH
    Prenatal Exposures and Child Health Outcomes: A Statewide Study
    Role: Co-Principal Investigator
  5. 1UG3OD023285-01 (BARONE, CHARLES) Sep 21, 2016 - Aug 31, 2018
    NIH
    Prenatal Exposures and Child Health Outcomes: A Statewide Study
    Role: Site-PI

Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Morrison CS, Chen PL, Yamamoto H, Gao X, Chipato T, Anderson S, Barbieri R, Salata R, Doncel GF, Fichorova RN. Concomitant Imbalances of Systemic and Mucosal Immunity Increase HIV Acquisition Risk. J Acquir Immune Defic Syndr. 2020 May 01; 84(1):85-91. PMID: 31985699.
    Citations:    
  2. Millett CE, Harder J, Locascio JJ, Shanahan M, Santone G, Fichorova RN, Corrigan A, Baecher-Allan C, Burdick KE. TNF-a and its soluble receptors mediate the relationship between prior severe mood episodes and cognitive dysfunction in euthymic bipolar disorder. Brain Behav Immun. 2020 Apr 06. PMID: 32272224.
    Citations:    
  3. Lu X, Kugadas A, Smith-Page K, Lamb J, Lin T, Ru Y, Morley SC, Fichorova R, Mittal SK, Chauhan SK, Littleton S, Saban D, Gadjeva M. Neutrophil L-Plastin Controls Ocular Paucibacteriality and Susceptibility to Keratitis. Front Immunol. 2020; 11:547. PMID: 32318063.
    Citations:    
  4. Fichorova RN, Morrison CS, Chen PL, Yamamoto HS, Govender Y, Junaid D, Ryan S, Kwok C, Chipato T, Salata RA, Doncel GF. Aberrant cervical innate immunity predicts onset of dysbiosis and sexually transmitted infections in women of reproductive age. PLoS One. 2020; 15(1):e0224359. PMID: 31914129.
    Citations:    
  5. Sasamoto N, Babic A, Rosner BA, Fortner RT, Vitonis AF, Yamamoto H, Fichorova RN, Titus LJ, Tjønneland A, Hansen L, Kvaskoff M, Fournier A, Mancini FR, Boeing H, Trichopoulou A, Peppa E, Karakatsani A, Palli D, Grioni S, Mattiello A, Tumino R, Fiano V, Onland-Moret NC, Weiderpass E, Gram IT, Quirós JR, Lujan-Barroso L, Sánchez MJ, Colorado-Yohar S, Barricarte A, Amiano P, Idahl A, Lundin E, Sartor H, Khaw KT, Key TJ, Muller D, Riboli E, Gunter M, Dossus L, Trabert B, Wentzensen N, Kaaks R, Cramer DW, Tworoger SS, Terry KL. Development and validation of circulating CA125 prediction models in postmenopausal women. J Ovarian Res. 2019 Nov 26; 12(1):116. PMID: 31771659.
    Citations:    
  6. Millett CE, Perez-Rodriguez M, Shanahan M, Larsen E, Yamamoto HS, Bukowski C, Fichorova R, Burdick KE. C-reactive protein is associated with cognitive performance in a large cohort of euthymic patients with bipolar disorder. Mol Psychiatry. 2019 Nov 19. PMID: 31740754.
    Citations:    
  7. Padula AM, Monk C, Brennan PA, Borders A, Barrett ES, McEvoy CT, Foss S, Desai P, Alshawabkeh A, Wurth R, Salafia C, Fichorova R, Varshavsky J, Kress A, Woodruff TJ, Morello-Frosch R. A review of maternal prenatal exposures to environmental chemicals and psychosocial stressors-implications for research on perinatal outcomes in the ECHO program. J Perinatol. 2020 Jan; 40(1):10-24. PMID: 31616048.
    Citations:    
  8. Dheilly NM, Martínez Martínez J, Rosario K, Brindley PJ, Fichorova RN, Kaye JZ, Kohl KD, Knoll LJ, Lukeš J, Perkins SL, Poulin R, Schriml L, Thompson LR. Parasite microbiome project: Grand challenges. PLoS Pathog. 2019 10; 15(10):e1008028. PMID: 31600339.
    Citations:    
  9. Thurman A, Cunningham T, Fichorova R, Herold BC, Hillier SL, Chandra N, Doncel GF. A phase I randomized safety study of a single-size silicone rubber diaphragm used with or without a lactic-acid-containing diaphragm gel. Contraception. 2019 12; 100(6):430-437. PMID: 31442441.
    Citations:    
  10. Dheilly NM, Ewald PW, Brindley PJ, Fichorova RN, Thomas F. Parasite-microbe-host interactions and cancer risk. PLoS Pathog. 2019 08; 15(8):e1007912. PMID: 31415672.
    Citations:    
  11. Bulka CM, Dammann O, Santos HP, VanderVeen DK, Smeester L, Fichorova R, O'Shea TM, Fry RC. Placental CpG Methylation of Inflammation, Angiogenic, and Neurotrophic Genes and Retinopathy of Prematurity. Invest Ophthalmol Vis Sci. 2019 07 01; 60(8):2888-2894. PMID: 31266060.
    Citations:    
  12. Cox LM, Seekatz AM, Fichorova RN. Introduction to the special issue for The anaerobe society of the America's 14th Biennial congress in Las Vegas. Anaerobe. 2019 Aug; 58:1-5. PMID: 31255715.
    Citations:    
  13. Thurman A, Chandra N, Schwartz JL, Brache V, Chen BA, Asin S, Rollenhagen C, Herold BC, Fichorova RN, Hillier SL, Weiner DH, Mauck C, Doncel GF. The Effect of Hormonal Contraception on Cervicovaginal Mucosal End Points Associated with HIV Acquisition. AIDS Res Hum Retroviruses. 2019 09; 35(9):853-864. PMID: 30997816.
    Citations:    
  14. Kuban KCK, Jara H, O'Shea TM, Heeren T, Joseph RM, Fichorova RN, Alshamrani K, Aakil A, Beaulieu F, Horn M, Douglass LM, Frazier JA, Hirtz D, Rollins JV, Cochran D, Paneth N. Association of Circulating Proinflammatory and Anti-inflammatory Protein Biomarkers in Extremely Preterm Born Children with Subsequent Brain Magnetic Resonance Imaging Volumes and Cognitive Function at Age 10 Years. J Pediatr. 2019 07; 210:81-90.e3. PMID: 31076229.
    Citations:    
  15. Govender Y, Gabriel I, Minassian V, Fichorova R. The Current Evidence on the Association Between the Urinary Microbiome and Urinary Incontinence in Women. Front Cell Infect Microbiol. 2019; 9:133. PMID: 31119104.
    Citations:    
  16. Sasamoto N, Babic A, Rosner BA, Fortner RT, Vitonis AF, Yamamoto H, Fichorova RN, Tjønneland A, Hansen L, Overvad K, Kvaskoff M, Fournier A, Romana Mancini F, Boeing H, Trichopoulou A, Peppa E, Karakatsani A, Palli D, Pala V, Mattiello A, Tumino R, Grasso CC, Onland-Moret NC, Weiderpass E, Quirós JR, Lujan-Barroso L, Rodríguez-Barranco M, Colorado-Yohar S, Barricarte A, Dorronsoro M, Idahl A, Lundin E, Sartor H, Khaw KT, Key TJ, Muller D, Riboli E, Gunter MJ, Dossus L, Kaaks R, Cramer DW, Tworoger SS, Terry KL. Predicting Circulating CA125 Levels among Healthy Premenopausal Women. Cancer Epidemiol Biomarkers Prev. 2019 06; 28(6):1076-1085. PMID: 30948451.
    Citations:    
  17. Pandit H, Kale K, Yamamoto H, Thakur G, Rokade S, Chakraborty P, Vasudevan M, Kishore U, Madan T, Fichorova RN. Surfactant Protein D Reverses the Gene Signature of Transepithelial HIV-1 Passage and Restricts the Viral Transfer Across the Vaginal Barrier. Front Immunol. 2019; 10:264. PMID: 30984160.
    Citations:    
  18. Leviton A, Allred EN, Dammann O, Joseph RM, Fichorova RN, O'Shea TM, Kuban KCK. Socioeconomic status and early blood concentrations of inflammation-related and neurotrophic proteins among extremely preterm newborns. PLoS One. 2019; 14(3):e0214154. PMID: 30913246.
    Citations:    
  19. Leviton A, Allred EN, Fichorova RN, VanderVeen DK, O'Shea TM, Kuban K, Dammann O. Early Postnatal IGF-1 and IGFBP-1 Blood Levels in Extremely Preterm Infants: Relationships with Indicators of Placental Insufficiency and with Systemic Inflammation. Am J Perinatol. 2019 12; 36(14):1442-1452. PMID: 30685870.
    Citations:    Fields:    
  20. Hipwell AE, Kahn LG, Factor-Litvak P, Porucznik CA, Siegel EL, Fichorova RN, Hamman RF, Klein-Fedyshin M, Harley KG. Exposure to non-persistent chemicals in consumer products and fecundability: a systematic review. Hum Reprod Update. 2019 01 01; 25(1):51-71. PMID: 30307509.
    Citations:    Fields:    
  21. Vicier C, Werner L, Chipman J, Harshman LC, Patil DH, Fichorova RN, Rider JR, Sanda MG, Mucci LA, Sweeney CJ. Elevated Serum Cytokines and Trichomonas vaginalis Serology at Diagnosis Are Not Associated With Higher Gleason Grade or Lethal Prostate Cancer. Clin Genitourin Cancer. 2019 Feb; 17(1):32-37. PMID: 30348512.
    Citations:    Fields:    
  22. Leviton A, Joseph RM, Fichorova RN, Allred EN, Gerry Taylor H, Michael O'Shea T, Dammann O. Executive Dysfunction Early Postnatal Biomarkers among Children Born Extremely Preterm. J Neuroimmune Pharmacol. 2019 06; 14(2):188-199. PMID: 30191383.
    Citations:    Fields:    
  23. Morrison CS, Fichorova R, Chen PL, Kwok C, Deese J, Yamamoto H, Anderson S, Chipato T, Salata R, Doncel GF. A Longitudinal Assessment of Cervical Inflammation and Immunity Associated with HIV-1 Infection, Hormonal Contraception, and Pregnancy. AIDS Res Hum Retroviruses. 2018 10; 34(10):889-899. PMID: 30047279.
    Citations:    Fields:    
  24. Kuban KCK, Heeren T, O'Shea TM, Joseph RM, Fichorova RN, Douglass L, Jara H, Frazier JA, Hirtz D, Taylor HG, Rollins JV, Paneth N. Among Children Born Extremely Preterm a Higher Level of Circulating Neurotrophins Is Associated with Lower Risk of Cognitive Impairment at School Age. J Pediatr. 2018 10; 201:40-48.e4. PMID: 30029870.
    Citations:    Fields:    
  25. Thurman AR, Schwartz JL, Brache V, Clark MR, McCormick T, Chandra N, Marzinke MA, Stanczyk FZ, Dezzutti CS, Hillier SL, Herold BC, Fichorova R, Asin SN, Rollenhagen C, Weiner D, Kiser P, Doncel GF. Randomized, placebo controlled phase I trial of safety, pharmacokinetics, pharmacodynamics and acceptability of tenofovir and tenofovir plus levonorgestrel vaginal rings in women. PLoS One. 2018; 13(6):e0199778. PMID: 29953547.
    Citations:    Fields:    Translation:HumansCellsCTClinical Trials
  26. Leviton A, Joseph RM, Allred EN, Fichorova RN, O'Shea TM, Kuban KKC, Dammann O. The risk of neurodevelopmental disorders at age 10?years associated with blood concentrations of interleukins 4 and 10 during the first postnatal month of children born extremely preterm. Cytokine. 2018 10; 110:181-188. PMID: 29763840.
    Citations:    Fields:    
  27. Cramer DW, Fichorova RN, Terry KL, Yamamoto H, Vitonis AF, Ardanaz E, Aune D, Boeing H, Brändstedt J, Boutron-Ruault MC, Chirlaque MD, Dorronsoro M, Dossus L, Duell EJ, Gram IT, Gunter M, Hansen L, Idahl A, Johnson T, Khaw KT, Krogh V, Kvaskoff M, Mattiello A, Matullo G, Merritt MA, Nodin B, Orfanos P, Onland-Moret NC, Palli D, Peppa E, Quirós JR, Sánchez-Perez MJ, Severi G, Tjønneland A, Travis RC, Trichopoulou A, Tumino R, Weiderpass E, Fortner RT, Kaaks R. Anti-CA15.3 and Anti-CA125 Antibodies and Ovarian Cancer Risk: Results from the EPIC Cohort. Cancer Epidemiol Biomarkers Prev. 2018 07; 27(7):790-804. PMID: 29661801.
    Citations:    Fields:    
  28. Haimovici F, Anderson JL, Bates GW, Racowsky C, Ginsburg ES, Simovici D, Fichorova RN. Stress, anxiety, and depression of both partners in infertile couples are associated with cytokine levels and adverse IVF outcome. Am J Reprod Immunol. 2018 04; 79(4):e12832. PMID: 29528174.
    Citations:    Fields:    Translation:Humans
  29. Friedman KG, Sleeper LA, Fichorova RN, Weilnau T, Tworetzky W, Wilkins-Haug LE. Myocardial injury in fetal aortic stenosis: Insights from amniotic fluid analysis. Prenat Diagn. 2018 02; 38(3):190-195. PMID: 29327361.
    Citations:    Fields:    Translation:Humans
  30. Leviton A, Dammann O, Allred EN, Joseph RM, Fichorova RN, O'Shea TM, Kuban KCK. Neonatal systemic inflammation and the risk of low scores on measures of reading and mathematics achievement at age 10 years among children born extremely preterm. Int J Dev Neurosci. 2018 May; 66:45-53. PMID: 29413878.
    Citations:    Fields:    Translation:Humans
  31. Leviton A, Allred EN, Fichorova RN, O'Shea TM, Fordham LA, Kuban KKC, Dammann O. Circulating biomarkers in extremely preterm infants associated with ultrasound indicators of brain damage. Eur J Paediatr Neurol. 2018 May; 22(3):440-450. PMID: 29429901.
    Citations:    Fields:    Translation:Humans
  32. Perrin EM, O'Shea TM, Skinner AC, Bose C, Allred EN, Fichorova RN, van der Burg JW, Leviton A. Elevations of inflammatory proteins in neonatal blood are associated with obesity and overweight among 2-year-old children born extremely premature. Pediatr Res. 2018 06; 83(6):1110-1119. PMID: 29244802.
    Citations: 2     Fields:    
  33. Tomlinson MS, Bommarito PA, Martin EM, Smeester L, Fichorova RN, Onderdonk AB, Kuban KCK, O'Shea TM, Fry RC. Microorganisms in the human placenta are associated with altered CpG methylation of immune and inflammation-related genes. PLoS One. 2017; 12(12):e0188664. PMID: 29240761.
    Citations:    Fields:    Translation:HumansCells
  34. Fortner RT, Schock H, Le Cornet C, Hüsing A, Vitonis AF, Johnson TS, Fichorova RN, Fashemi T, Yamamoto HS, Tjønneland A, Hansen L, Overvad K, Boutron-Ruault MC, Kvaskoff M, Severi G, Boeing H, Trichopoulou A, Papatesta EM, La Vecchia C, Palli D, Sieri S, Tumino R, Sacerdote C, Mattiello A, Onland-Moret NC, Peeters PH, Bueno-de-Mesquita HBA, Weiderpass E, Quirós JR, Duell EJ, Sánchez MJ, Navarro C, Ardanaz E, Larrañaga N, Nodin B, Jirström K, Idahl A, Lundin E, Khaw KT, Travis RC, Gunter M, Johansson M, Dossus L, Merritt MA, Riboli E, Terry KL, Cramer DW, Kaaks R. Ovarian cancer early detection by circulating CA125 in the context of anti-CA125 autoantibody levels: Results from the EPIC cohort. Int J Cancer. 2018 04 01; 142(7):1355-1360. PMID: 29159934.
    Citations:    Fields:    Translation:Humans
  35. Holm M, Morken TS, Fichorova RN, VanderVeen DK, Allred EN, Dammann O, Leviton A. Systemic Inflammation-Associated Proteins and Retinopathy of Prematurity in Infants Born Before the 28th Week of Gestation. Invest Ophthalmol Vis Sci. 2017 12 01; 58(14):6419-6428. PMID: 29260199.
    Citations: 2     Fields:    Translation:Humans
  36. Yanni D, Korzeniewski SJ, Allred EN, Fichorova RN, O'Shea TM, Kuban K, Dammann O, Leviton A. Both antenatal and postnatal inflammation contribute information about the risk of brain damage in extremely preterm newborns. Pediatr Res. 2017 Oct; 82(4):691-696. PMID: 28549057.
    Citations: 2     Fields:    Translation:Humans
  37. Leviton A, Ryan S, Allred EN, Fichorova RN, Michael O'Shea T, Kuban K, Dammann O. Antecedents and early correlates of high and low concentrations of angiogenic proteins in extremely preterm newborns. Clin Chim Acta. 2017 Aug; 471:1-5. PMID: 28502557.
    Citations: 3     Fields:    Translation:Humans
  38. Cox LM, Theriot CM, Fichorova RN. Introduction to the special issue highlighting Anaerobe 2016. Anaerobe. 2017 06; 45:1-2. PMID: 28478276.
    Citations:    Fields:    Translation:Cells
  39. Allred EN, Dammann O, Fichorova RN, Hooper SR, Hunter SJ, Joseph RM, Kuban K, Leviton A, O'Shea TM, Scott MN. Systemic Inflammation during the First Postnatal Month and the Risk of Attention Deficit Hyperactivity Disorder Characteristics among 10 year-old Children Born Extremely Preterm. J Neuroimmune Pharmacol. 2017 09; 12(3):531-543. PMID: 28405874.
    Citations: 1     Fields:    Translation:Humans
  40. Leviton A, Allred EN, Yamamoto H, Fichorova RN, Kuban K, O'Shea TM, Dammann O. Antecedents and correlates of blood concentrations of neurotrophic growth factors in very preterm newborns. Cytokine. 2017 06; 94:21-28. PMID: 28396037.
    Citations: 3     Fields:    Translation:Humans
  41. Fichorova R, Fraga J, Rappelli P, Fiori PL. Trichomonas vaginalis infection in symbiosis with Trichomonasvirus and Mycoplasma. Res Microbiol. 2017 Nov - Dec; 168(9-10):882-891. PMID: 28366838.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  42. Dowling DJ, van Haren SD, Scheid A, Bergelson I, Kim D, Mancuso CJ, Foppen W, Ozonoff A, Fresh L, Theriot TB, Lackner AA, Fichorova RN, Smirnov D, Vasilakos JP, Beaurline JM, Tomai MA, Midkiff CC, Alvarez X, Blanchard JL, Gilbert MH, Aye PP, Levy O. TLR7/8 adjuvant overcomes newborn hyporesponsiveness to pneumococcal conjugate vaccine at birth. JCI Insight. 2017 03 23; 2(6):e91020. PMID: 28352660.
    Citations: 10     Fields:    
  43. Fortner RT, Vitonis AF, Schock H, Hüsing A, Johnson T, Fichorova RN, Fashemi T, Yamamoto HS, Tjønneland A, Hansen L, Overvad K, Boutron-Ruault MC, Kvaskoff M, Severi G, Boeing H, Trichopoulou A, Benetou V, La Vecchia C, Palli D, Sieri S, Tumino R, Matullo G, Mattiello A, Onland-Moret NC, Peeters PH, Weiderpass E, Gram IT, Jareid M, Quirós JR, Duell EJ, Sánchez MJ, Chirlaque MD, Ardanaz E, Larrañaga N, Nodin B, Brändstedt J, Idahl A, Khaw KT, Allen N, Gunter M, Johansson M, Dossus L, Merritt MA, Riboli E, Cramer DW, Kaaks R, Terry KL. Correlates of circulating ovarian cancer early detection markers and their contribution to discrimination of early detection models: results from the EPIC cohort. J Ovarian Res. 2017 Mar 20; 10(1):20. PMID: 28320479.
    Citations: 2     Fields:    Translation:HumansPHPublic Health
  44. Holm M, Austeng D, Fichorova RN, Allred EN, Kuban KC, O'Shea TM, Dammann O, Leviton A. Postnatal systemic inflammation and neuro-ophthalmologic dysfunctions in extremely low gestational age children. Acta Paediatr. 2017 Mar; 106(3):454-457. PMID: 27987368.
    Citations:    Fields:    Translation:Humans
  45. Alcaide ML, Rodriguez VJ, Brown MR, Pallikkuth S, Arheart K, Martinez O, Roach M, Fichorova RN, Jones DL, Pahwa S, Fischl MA. High Levels of Inflammatory Cytokines in the Reproductive Tract of Women with BV and Engaging in Intravaginal Douching: A Cross-Sectional Study of Participants in the Women Interagency HIV Study. AIDS Res Hum Retroviruses. 2017 04; 33(4):309-317. PMID: 27897054.
    Citations: 2     Fields:    Translation:Humans
  46. Kuban KC, Joseph RM, O'Shea TM, Heeren T, Fichorova RN, Douglass L, Jara H, Frazier JA, Hirtz D, Rollins JV, Paneth N. Circulating Inflammatory-Associated Proteins in the First Month of Life and Cognitive Impairment at Age 10 Years in Children Born Extremely Preterm. J Pediatr. 2017 01; 180:116-123.e1. PMID: 27788929.
    Citations: 3     Fields:    Translation:Humans
  47. Faden M, Holm M, Allred E, Fichorova R, Dammann O, Leviton A. Antenatal glucocorticoids and neonatal inflammation-associated proteins. Cytokine. 2016 12; 88:199-208. PMID: 27668972.
    Citations:    Fields:    Translation:HumansCTClinical Trials
  48. Kugadas A, Christiansen SH, Sankaranarayanan S, Surana NK, Gauguet S, Kunz R, Fichorova R, Vorup-Jensen T, Gadjeva M. Impact of Microbiota on Resistance to Ocular Pseudomonas aeruginosa-Induced Keratitis. PLoS Pathog. 2016 Sep; 12(9):e1005855. PMID: 27658245.
    Citations: 10     Fields:    
  49. Lee Y, Dizzell SE, Leung V, Nazli A, Zahoor MA, Fichorova RN, Kaushic C. Effects of Female Sex Hormones on Susceptibility to HSV-2 in Vaginal Cells Grown in Air-Liquid Interface. Viruses. 2016 08 30; 8(9). PMID: 27589787.
    Citations:    Fields:    Translation:HumansCells
  50. Holm M, Skranes J, Dammann O, Fichorova RN, Allred EN, Leviton A. Systemic endogenous erythropoietin and associated disorders in extremely preterm newborns. Arch Dis Child Fetal Neonatal Ed. 2016 Sep; 101(5):F458-63. PMID: 27173415.
    Citations: 2     Fields:    Translation:Humans
  51. Terry KL, Schock H, Fortner RT, Hüsing A, Fichorova RN, Yamamoto HS, Vitonis AF, Johnson T, Overvad K, Tjønneland A, Boutron-Ruault MC, Mesrine S, Severi G, Dossus L, Rinaldi S, Boeing H, Benetou V, Lagiou P, Trichopoulou A, Krogh V, Kuhn E, Panico S, Bueno-de-Mesquita HB, Onland-Moret NC, Peeters PH, Gram IT, Weiderpass E, Duell EJ, Sanchez MJ, Ardanaz E, Etxezarreta N, Navarro C, Idahl A, Lundin E, Jirström K, Manjer J, Wareham NJ, Khaw KT, Byrne KS, Travis RC, Gunter MJ, Merritt MA, Riboli E, Cramer DW, Kaaks R. A Prospective Evaluation of Early Detection Biomarkers for Ovarian Cancer in the European EPIC Cohort. Clin Cancer Res. 2016 Sep 15; 22(18):4664-75. PMID: 27060155.
    Citations: 12     Fields:    Translation:Humans
  52. Dammann O, Allred EN, Fichorova RN, Kuban K, O'Shea TM, Leviton A. Duration of Systemic Inflammation in the First Postnatal Month Among Infants Born Before the 28th Week of Gestation. Inflammation. 2016 Apr; 39(2):672-7. PMID: 26676589.
    Citations: 4     Fields:    Translation:Humans
  53. Onderdonk AB, Delaney ML, Fichorova RN. The Human Microbiome during Bacterial Vaginosis. Clin Microbiol Rev. 2016 Apr; 29(2):223-38. PMID: 26864580.
    Citations: 24     Fields:    Translation:HumansCells
  54. Turner AN, Carr Reese P, Chen PL, Kwok C, Jackson RD, Klebanoff MA, Fichorova RN, Chipato T, Morrison CS. Serum vitamin D status and bacterial vaginosis prevalence and incidence in Zimbabwean women. Am J Obstet Gynecol. 2016 09; 215(3):332.e1-332.e10. PMID: 26945606.
    Citations: 1     Fields:    Translation:Humans
  55. Mauck C, Chen PL, Morrison CS, Fichorova RN, Kwok C, Chipato T, Salata RA, Doncel GF. Biomarkers of Cervical Inflammation and Immunity Associated with Cervical Shedding of HIV-1. AIDS Res Hum Retroviruses. 2016 May; 32(5):443-51. PMID: 26650885.
    Citations: 3     Fields:    Translation:HumansCells
  56. Leviton A, Allred EN, Fichorova RN, Kuban KC, Michael O'Shea T, Dammann O. Systemic inflammation on postnatal days 21 and 28 and indicators of brain dysfunction 2years later among children born before the 28th week of gestation. Early Hum Dev. 2016 Feb; 93:25-32. PMID: 26735345.
    Citations: 10     Fields:    Translation:Humans
  57. Leviton A, Allred EN, Fichorova RN, Kuban KC, O'Shea TM, Dammann O. Antecedents of inflammation biomarkers in preterm newborns on days 21 and 28. Acta Paediatr. 2016 Mar; 105(3):274-80. PMID: 26610180.
    Citations: 2     Fields:    Translation:Humans
  58. Leviton A, Allred EN, Kuban KC, O'Shea TM, Paneth N, Onderdonk AB, Fichorova RN, Dammann O. The Development of Extremely Preterm Infants Born to Women Who Had Genitourinary Infections During Pregnancy. Am J Epidemiol. 2016 Jan 01; 183(1):28-35. PMID: 26667255.
    Citations: 1     Fields:    Translation:Humans
  59. Fichorova RN, Yamamoto HS, Fashemi T, Foley E, Ryan S, Beatty N, Dawood H, Hayes GR, St-Pierre G, Sato S, Singh BN. Trichomonas vaginalis Lipophosphoglycan Exploits Binding to Galectin-1 and -3 to Modulate Epithelial Immunity. J Biol Chem. 2016 Jan 08; 291(2):998-1013. PMID: 26589797.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  60. Heiss C, Wang Z, Black I, Azadi P, Fichorova RN, Singh BN. Novel structural features of the immunocompetent ceramide phospho-inositol glycan core from Trichomonas vaginalis. Carbohydr Res. 2016 Jan; 419:51-9. PMID: 26671321.
    Citations:    Fields:    Translation:Animals
  61. Fichorova RN, Chen PL, Morrison CS, Doncel GF, Mendonca K, Kwok C, Chipato T, Salata R, Mauck C. The Contribution of Cervicovaginal Infections to the Immunomodulatory Effects of Hormonal Contraception. mBio. 2015 Sep 01; 6(5):e00221-15. PMID: 26330510.
    Citations: 16     Fields:    Translation:Humans
  62. Sorond FA, Tan CO, LaRose S, Monk AD, Fichorova R, Ryan S, Lipsitz LA. Deferoxamine, Cerebrovascular Hemodynamics, and Vascular Aging: Potential Role for Hypoxia-Inducible Transcription Factor-1-Regulated Pathways. Stroke. 2015 Sep; 46(9):2576-83. PMID: 26304864.
    Citations: 4     Fields:    Translation:HumansCells
  63. Thurman AR, Kimble T, Herold B, Mesquita PM, Fichorova RN, Dawood HY, Fashemi T, Chandra N, Rabe L, Cunningham TD, Anderson S, Schwartz J, Doncel G. Bacterial Vaginosis and Subclinical Markers of Genital Tract Inflammation and Mucosal Immunity. AIDS Res Hum Retroviruses. 2015 Nov; 31(11):1139-52. PMID: 26204200.
    Citations: 10     Fields:    Translation:Humans
  64. Inci F, Filippini C, Baday M, Ozen MO, Calamak S, Durmus NG, Wang S, Hanhauser E, Hobbs KS, Juillard F, Kuang PP, Vetter ML, Carocci M, Yamamoto HS, Takagi Y, Yildiz UH, Akin D, Wesemann DR, Singhal A, Yang PL, Nibert ML, Fichorova RN, Lau DT, Henrich TJ, Kaye KM, Schachter SC, Kuritzkes DR, Steinmetz LM, Gambhir SS, Davis RW, Demirci U. Multitarget, quantitative nanoplasmonic electrical field-enhanced resonating device (NE2RD) for diagnostics. Proc Natl Acad Sci U S A. 2015 Aug 11; 112(32):E4354-63. PMID: 26195743.
    Citations: 7     Fields:    Translation:HumansCells
  65. Zalenskaya IA, Joseph T, Bavarva J, Yousefieh N, Jackson SS, Fashemi T, Yamamoto HS, Settlage R, Fichorova RN, Doncel GF. Gene Expression Profiling of Human Vaginal Cells In Vitro Discriminates Compounds with Pro-Inflammatory and Mucosa-Altering Properties: Novel Biomarkers for Preclinical Testing of HIV Microbicide Candidates. PLoS One. 2015; 10(6):e0128557. PMID: 26052926.
    Citations: 5     Fields:    Translation:HumansCells
  66. Anahtar MN, Byrne EH, Doherty KE, Bowman BA, Yamamoto HS, Soumillon M, Padavattan N, Ismail N, Moodley A, Sabatini ME, Ghebremichael MS, Nusbaum C, Huttenhower C, Virgin HW, Ndung'u T, Dong KL, Walker BD, Fichorova RN, Kwon DS. Cervicovaginal bacteria are a major modulator of host inflammatory responses in the female genital tract. Immunity. 2015 May 19; 42(5):965-76. PMID: 25992865.
    Citations: 65     Fields:    Translation:HumansCells
  67. Fichorova RN, Mendonca K, Yamamoto HS, Murray R, Chandra N, Doncel GF. A quantitative multiplex nuclease protection assay reveals immunotoxicity gene expression profiles in the rabbit model for vaginal drug safety evaluation. Toxicol Appl Pharmacol. 2015 Jun 15; 285(3):198-206. PMID: 25818602.
    Citations: 3     Fields:    Translation:AnimalsCells
  68. Korzeniewski SJ, Allred E, Logan JW, Fichorova RN, Engelke S, Kuban KC, O'Shea TM, Paneth N, Holm M, Dammann O, Leviton A. Elevated endogenous erythropoietin concentrations are associated with increased risk of brain damage in extremely preterm neonates. PLoS One. 2015; 10(3):e0115083. PMID: 25793991.
    Citations: 6     Fields:    Translation:Humans
  69. Buvé A, Fichorova RN. Reply to 'sexual networks, HIV, race and bacterial vaginosis'. AIDS. 2015 Mar 13; 29(5):642-3. PMID: 25710291.
    Citations:    Fields:    Translation:Humans
  70. Kyongo JK, Crucitti T, Menten J, Hardy L, Cools P, Michiels J, Delany-Moretlwe S, Mwaura M, Ndayisaba G, Joseph S, Fichorova R, van de Wijgert J, Vanham G, Ariën KK, Jespers V. Cross-Sectional Analysis of Selected Genital Tract Immunological Markers and Molecular Vaginal Microbiota in Sub-Saharan African Women, with Relevance to HIV Risk and Prevention. Clin Vaccine Immunol. 2015 May; 22(5):526-38. PMID: 25761460.
    Citations: 20     Fields:    Translation:HumansCells
  71. Fichorova, RN. Drug Delivery and Development of Anti-HIV Microbicides (Neves, Sarmento, Editors). Safety aspects of topical anti-HIV microbicides. 2015. View Publication.
  72. Guseh SH, Feinberg BB, Dawood HY, Yamamoto HS, Fichorova RN, Burwick RM. Urinary excretion of C5b-9 is associated with the anti-angiogenic state in severe preeclampsia. Am J Reprod Immunol. 2015 May; 73(5):437-44. PMID: 25521546.
    Citations: 5     Fields:    Translation:HumansCTClinical Trials
  73. Korzeniewski SJ, Soto-Rivera CL, Fichorova RN, Allred EN, Kuban KC, O'Shea TM, Paneth N, Agus M, Dammann O, Leviton A. Are preterm newborns who have relative hyperthyrotropinemia at increased risk of brain damage? J Pediatr Endocrinol Metab. 2014 Nov; 27(11-12):1077-88. PMID: 24897395.
    Citations: 4     Fields:    Translation:Humans
  74. Buve A, Jespers V, Crucitti T, Fichorova RN. The vaginal microbiota and susceptibility to HIV. AIDS. 2014 Oct 23; 28(16):2333-44. PMID: 25389548.
    Citations: 24     Fields:    Translation:Humans
  75. Kuban KC, O'Shea TM, Allred EN, Fichorova RN, Heeren T, Paneth N, Hirtz D, Dammann O, Leviton A. The breadth and type of systemic inflammation and the risk of adverse neurological outcomes in extremely low gestation newborns. Pediatr Neurol. 2015 Jan; 52(1):42-8. PMID: 25459361.
    Citations: 13     Fields:    Translation:Humans
  76. Thurman AR, Kimble TD, Cunningham TD, Herold BC, Mesquita P, Huber A, Fichorova RN, Dawood HY, Fashemi T, Chandra N, Schwartz JL, Doncel GF. Effect of Bacterial Vaginosis on Markers of Genital Tract Inflammation and Mucosal Immunity: Mechanisms for Susceptibility to HIV Infection. AIDS Res Hum Retroviruses. 2014 Oct; 30 Suppl 1:A30. PMID: 25357823.
    Citations:    
  77. Fashemi T, Yamamoto H, Max N, Tsibris A, Fichorova R. Endosymbiont Trichomonas Vaginalis Virus as a Target for HIV Prevention. AIDS Res Hum Retroviruses. 2014 Oct; 30 Suppl 1:A241-2. PMID: 25357679.
    Citations:    
  78. Kyongo JK, Crucitti T, Menten J, Hardy L, Cools P, Michiels J, Delany-Moretlwe S, Mwaura M, Ndayisaba G, Joseph S, Fichorova R, van de Wijgert J, Vanham G, Ariën KK, Jespers V. Genital Tract Immunological Markers in Sub-Saharan African Women with Relevance to HIV Risk and Prevention. AIDS Res Hum Retroviruses. 2014 Oct; 30 Suppl 1:A233. PMID: 25357655.
    Citations:    
  79. Mauck CK, Chen PL, Morrison C, Fichorova R, Kwok C, Chipato T, Salata R, Doncel G. Biomarkers of Cervical Inflammation and Immunity Associated with Cervical HIV-1 RNA. AIDS Res Hum Retroviruses. 2014 Oct; 30 Suppl 1:A181. PMID: 25357510.
    Citations:    
  80. Fichorova RN, Beatty N, Sassi RR, Yamamoto HS, Allred EN, Leviton A. Systemic inflammation in the extremely low gestational age newborn following maternal genitourinary infections. Am J Reprod Immunol. 2015 Feb; 73(2):162-74. PMID: 25164433.
    Citations: 13     Fields:    Translation:Humans
  81. Soto-Rivera CL, Fichorova RN, Allred EN, Van Marter LJ, Shah B, Martin CR, Agus MS, Leviton A. The relationship between TSH and systemic inflammation in extremely preterm newborns. Endocrine. 2015 Mar; 48(2):595-602. PMID: 24996532.
    Citations: 7     Fields:    Translation:Humans
  82. Burwick RM, Easter SR, Dawood HY, Yamamoto HS, Fichorova RN, Feinberg BB. Complement activation and kidney injury molecule-1-associated proximal tubule injury in severe preeclampsia. Hypertension. 2014 Oct; 64(4):833-8. PMID: 24958504.
    Citations: 4     Fields:    Translation:Humans
  83. Turner AN, Carr Reese P, Fields KS, Anderson J, Ervin M, Davis JA, Fichorova RN, Roberts MW, Klebanoff MA, Jackson RD. A blinded, randomized controlled trial of high-dose vitamin D supplementation to reduce recurrence of bacterial vaginosis. Am J Obstet Gynecol. 2014 Nov; 211(5):479.e1-479.e13. PMID: 24949544.
    Citations: 6     Fields:    Translation:Humans
  84. Logan JW, Allred EN, Fichorova RN, Engelke S, Dammann O, Leviton A. Endogenous erythropoietin varies significantly with inflammation-related proteins in extremely premature newborns. Cytokine. 2014 Sep; 69(1):22-8. PMID: 25022958.
    Citations: 4     Fields:    Translation:Humans
  85. Morrison C, Fichorova RN, Mauck C, Chen PL, Kwok C, Chipato T, Salata R, Doncel GF. Cervical inflammation and immunity associated with hormonal contraception, pregnancy, and HIV-1 seroconversion. J Acquir Immune Defic Syndr. 2014 Jun 01; 66(2):109-17. PMID: 24413042.
    Citations: 33     Fields:    Translation:Humans
  86. O'Shea TM, Joseph RM, Kuban KC, Allred EN, Ware J, Coster T, Fichorova RN, Dammann O, Leviton A. Elevated blood levels of inflammation-related proteins are associated with an attention problem at age 24 mo in extremely preterm infants. Pediatr Res. 2014 Jun; 75(6):781-7. PMID: 24614800.
    Citations: 22     Fields:    Translation:Humans
  87. Sharma J, Gray KP, Harshman LC, Evan C, Nakabayashi M, Fichorova R, Rider J, Mucci L, Kantoff PW, Sweeney CJ. Elevated IL-8, TNF-a, and MCP-1 in men with metastatic prostate cancer starting androgen-deprivation therapy (ADT) are associated with shorter time to castration-resistance and overall survival. Prostate. 2014 Jun; 74(8):820-8. PMID: 24668612.
    Citations: 20     Fields:    Translation:HumansCells
  88. Kuban KC, O'Shea TM, Allred EN, Paneth N, Hirtz D, Fichorova RN, Leviton A. Systemic inflammation and cerebral palsy risk in extremely preterm infants. J Child Neurol. 2014 Dec; 29(12):1692-8. PMID: 24646503.
    Citations: 22     Fields:    Translation:Humans
  89. Gregory KE, Winston AB, Yamamoto HS, Dawood HY, Fashemi T, Fichorova RN, Van Marter LJ. Urinary intestinal fatty acid binding protein predicts necrotizing enterocolitis. J Pediatr. 2014 Jun; 164(6):1486-8. PMID: 24636854.
    Citations: 11     Fields:    Translation:Humans
  90. Khwaja OS, Ho E, Barnes KV, O'Leary HM, Pereira LM, Finkelstein Y, Nelson CA, Vogel-Farley V, DeGregorio G, Holm IA, Khatwa U, Kapur K, Alexander ME, Finnegan DM, Cantwell NG, Walco AC, Rappaport L, Gregas M, Fichorova RN, Shannon MW, Sur M, Kaufmann WE. Safety, pharmacokinetics, and preliminary assessment of efficacy of mecasermin (recombinant human IGF-1) for the treatment of Rett syndrome. Proc Natl Acad Sci U S A. 2014 Mar 25; 111(12):4596-601. PMID: 24623853.
    Citations: 43     Fields:    Translation:Humans
  91. Wei C, Lu Q, Khoo SK, Lenski M, Fichorova RN, Leviton A, Paneth N. Comparison of frozen and unfrozen blood spots for gene expression studies. J Pediatr. 2014 Jan; 164(1):189-191.e1. PMID: 24209717.
    Citations: 4     Fields:    Translation:HumansCellsPHPublic Health
  92. Sharma J, Gray KP, Evan C, Nakabayashi M, Fichorova R, Rider J, Mucci L, Kantoff PW, Sweeney CJ. Elevated insulin-like growth factor binding protein-1 (IGFBP-1) in men with metastatic prostate cancer starting androgen deprivation therapy (ADT) is associated with shorter time to castration resistance and overall survival. Prostate. 2014 Feb; 74(3):225-34. PMID: 24132762.
    Citations: 9     Fields:    Translation:Humans
  93. van der Burg JW, Allred EN, McElrath TF, Fichorova RN, Kuban K, O'Shea TM, Dammann O, Leviton A. Is maternal obesity associated with sustained inflammation in extremely low gestational age newborns? Early Hum Dev. 2013 Dec; 89(12):949-55. PMID: 24090868.
    Citations: 13     Fields:    Translation:Humans
  94. Burwick RM, Fichorova RN, Dawood HY, Yamamoto HS, Feinberg BB. Urinary excretion of C5b-9 in severe preeclampsia: tipping the balance of complement activation in pregnancy. Hypertension. 2013 Dec; 62(6):1040-5. PMID: 24060886.
    Citations: 16     Fields:    Translation:Humans
  95. Mauck CK, Lai JJ, Weiner DH, Chandra N, Fichorova RN, Dezzutti CS, Hillier SL, Archer DF, Creinin MD, Schwartz JL, Callahan MM, Doncel GF. Toward early safety alert endpoints: exploring biomarkers suggestive of microbicide failure. AIDS Res Hum Retroviruses. 2013 Nov; 29(11):1475-86. PMID: 23885658.
    Citations: 8     Fields:    Translation:HumansCTClinical Trials
  96. Cramer DW, Williams K, Vitonis AF, Yamamoto HS, Stuebe A, Welch WR, Titus L, Fichorova RN. Puerperal mastitis: a reproductive event of importance affecting anti-mucin antibody levels and ovarian cancer risk. Cancer Causes Control. 2013 Nov; 24(11):1911-23. PMID: 23925696.
    Citations: 2     Fields:    Translation:Humans
  97. McElrath TF, Allred EN, Van Marter L, Fichorova RN, Leviton A. Perinatal systemic inflammatory responses of growth-restricted preterm newborns. Acta Paediatr. 2013 Oct; 102(10):e439-42. PMID: 23819682.
    Citations: 11     Fields:    Translation:Humans
  98. Fichorova RN, Buck OR, Yamamoto HS, Fashemi T, Dawood HY, Fashemi B, Hayes GR, Beach DH, Takagi Y, Delaney ML, Nibert ML, Singh BN, Onderdonk AB. The villain team-up or how Trichomonas vaginalis and bacterial vaginosis alter innate immunity in concert. Sex Transm Infect. 2013 Sep; 89(6):460-6. PMID: 23903808.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  99. Cywes-Bentley C, Skurnik D, Zaidi T, Roux D, Deoliveira RB, Garrett WS, Lu X, O'Malley J, Kinzel K, Zaidi T, Rey A, Perrin C, Fichorova RN, Kayatani AK, Maira-Litràn T, Gening ML, Tsvetkov YE, Nifantiev NE, Bakaletz LO, Pelton SI, Golenbock DT, Pier GB. Antibody to a conserved antigenic target is protective against diverse prokaryotic and eukaryotic pathogens. Proc Natl Acad Sci U S A. 2013 Jun 11; 110(24):E2209-18. PMID: 23716675.
    Citations: 36     Fields:    Translation:HumansAnimalsCells
  100. Parent KN, Takagi Y, Cardone G, Olson NH, Ericsson M, Yang M, Lee Y, Asara JM, Fichorova RN, Baker TS, Nibert ML. Structure of a protozoan virus from the human genitourinary parasite Trichomonas vaginalis. mBio. 2013 Apr 02; 4(2). PMID: 23549915.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  101. Fashemi B, Delaney ML, Onderdonk AB, Fichorova RN. Effects of feminine hygiene products on the vaginal mucosal biome. Microb Ecol Health Dis. 2013; 24. PMID: 24009546.
    Citations: 5     
  102. Taylor BD, Holzman CB, Fichorova RN, Tian Y, Jones NM, Fu W, Senagore PK. Inflammation biomarkers in vaginal fluid and preterm delivery. Hum Reprod. 2013 Apr; 28(4):942-52. PMID: 23416276.
    Citations: 16     Fields:    Translation:Humans
  103. Huppert JS, Huang B, Chen C, Dawood HY, Fichorova RN. Clinical evidence for the role of Trichomonas vaginalis in regulation of secretory leukocyte protease inhibitor in the female genital tract. J Infect Dis. 2013 May 01; 207(9):1462-70. PMID: 23355743.
    Citations: 8     Fields:    Translation:HumansAnimals
  104. Yamamoto HS, Xu Q, Fichorova RN. Homeostatic properties of Lactobacillus jensenii engineered as a live vaginal anti-HIV microbicide. BMC Microbiol. 2013 Jan 08; 13:4. PMID: 23298379.
    Citations: 11     Fields:    Translation:HumansCells
  105. O'Shea TM, Shah B, Allred EN, Fichorova RN, Kuban KC, Dammann O, Leviton A. Inflammation-initiating illnesses, inflammation-related proteins, and cognitive impairment in extremely preterm infants. Brain Behav Immun. 2013 Mar; 29:104-12. PMID: 23295265.
    Citations: 29     Fields:    Translation:HumansCells
  106. Leviton A, Fichorova RN, O'Shea TM, Kuban K, Paneth N, Dammann O, Allred EN. Two-hit model of brain damage in the very preterm newborn: small for gestational age and postnatal systemic inflammation. Pediatr Res. 2013 Mar; 73(3):362-70. PMID: 23364171.
    Citations: 25     Fields:    Translation:Humans
  107. Bose CL, Laughon MM, Allred EN, O'Shea TM, Van Marter LJ, Ehrenkranz RA, Fichorova RN, Leviton A. Systemic inflammation associated with mechanical ventilation among extremely preterm infants. Cytokine. 2013 Jan; 61(1):315-22. PMID: 23148992.
    Citations: 35     Fields:    Translation:Humans
  108. Fichorova RN, Lee Y, Yamamoto HS, Takagi Y, Hayes GR, Goodman RP, Chepa-Lotrea X, Buck OR, Murray R, Kula T, Beach DH, Singh BN, Nibert ML. Endobiont viruses sensed by the human host - beyond conventional antiparasitic therapy. PLoS One. 2012; 7(11):e48418. PMID: 23144878.
    Citations: 32     Fields:    Translation:HumansAnimalsCells
  109. Leviton A, Allred EN, Dammann O, Engelke S, Fichorova RN, Hirtz D, Kuban KC, Ment LR, O'shea TM, Paneth N, Shah B, Schreiber MD. Systemic inflammation, intraventricular hemorrhage, and white matter injury. J Child Neurol. 2013 Dec; 28(12):1637-45. PMID: 23112243.
    Citations: 13     Fields:    Translation:Humans
  110. Martin CR, Bellomy M, Allred EN, Fichorova RN, Leviton A. Systemic inflammation associated with severe intestinal injury in extremely low gestational age newborns. Fetal Pediatr Pathol. 2013 Jun; 32(3):222-34. PMID: 23002960.
    Citations: 14     Fields:    Translation:Humans
  111. Kyongo JK, Jespers V, Goovaerts O, Michiels J, Menten J, Fichorova RN, Crucitti T, Vanham G, Ariën KK. Searching for lower female genital tract soluble and cellular biomarkers: defining levels and predictors in a cohort of healthy Caucasian women. PLoS One. 2012; 7(8):e43951. PMID: 22952818.
    Citations: 27     Fields:    Translation:HumansCells
  112. Singh M, Kindelberger D, Nagymanyoki Z, Ng SW, Quick CM, Yamamoto H, Fichorova R, Fulop V, Berkowitz RS. Vascular endothelial growth factors and their receptors and regulators in gestational trophoblastic diseases and normal placenta. J Reprod Med. 2012 May-Jun; 57(5-6):197-203. PMID: 22696812.
    Citations: 2     Fields:    Translation:HumansCells
  113. Sharma J, Gray KP, Nakabayashi M, Petrozziello G, Evan C, Fichorova R, Kantoff PW, Sweeney C. Use of elevated insulin-like growth factor binding protein-1 (IGFBP-1) to predict outcomes in men with metastatic prostate cancer treated with androgen-deprivation therapy (ADT). J Clin Oncol. 2012 Feb 10; 30(5_suppl):191. PMID: 28143201.
    Citations:    
  114. Sharma J, Gray KP, Nakabayashi M, Petrozziello G, Evan C, Fichorova R, Kantoff PW, Sweeney C. Use of elevated baseline IL-8, CCL-2, and TNFa to predict for shorter overall survival (OS) in men with metastatic prostate cancer initiating androgen-deprivation therapy (ADT). J Clin Oncol. 2012 Feb 10; 30(5_suppl):13. PMID: 28142894.
    Citations:    
  115. Trivedi S, Joachim M, McElrath T, Kliman HJ, Allred EN, Fichorova RN, Onderdonk A, Heitor F, Chaychi L, Leviton A, Majzoub JA. Fetal-placental inflammation, but not adrenal activation, is associated with extreme preterm delivery. Am J Obstet Gynecol. 2012 Mar; 206(3):236.e1-8. PMID: 22264652.
    Citations: 11     Fields:    Translation:Humans
  116. Leviton A, O'Shea TM, Bednarek FJ, Allred EN, Fichorova RN, Dammann O. Systemic responses of preterm newborns with presumed or documented bacteraemia. Acta Paediatr. 2012 Apr; 101(4):355-9. PMID: 22085230.
    Citations: 24     Fields:    Translation:Humans
  117. Leviton A, Allred EN, Yamamoto H, Fichorova RN. Relationships among the concentrations of 25 inflammation-associated proteins during the first postnatal weeks in the blood of infants born before the 28th week of gestation. Cytokine. 2012 Jan; 57(1):182-90. PMID: 22133344.
    Citations: 21     Fields:    Translation:Humans
  118. Fichorova RN, Yamamoto HS, Delaney ML, Onderdonk AB, Doncel GF. Novel vaginal microflora colonization model providing new insight into microbicide mechanism of action. mBio. 2011; 2(6):e00168-11. PMID: 22027006.
    Citations: 32     Fields:    Translation:HumansCells
  119. O'Shea TM, Allred EN, Kuban KC, Dammann O, Paneth N, Fichorova R, Hirtz D, Leviton A. Elevated concentrations of inflammation-related proteins in postnatal blood predict severe developmental delay at 2 years of age in extremely preterm infants. J Pediatr. 2012 Mar; 160(3):395-401.e4. PMID: 22000304.
    Citations: 42     Fields:    Translation:Humans
  120. Zaidi T, Reidy T, D'Ortona S, Fichorova R, Pier G, Gadjeva M. CD74 deficiency ameliorates Pseudomonas aeruginosa-induced ocular infection. Sci Rep. 2011; 1:58. PMID: 22355577.
    Citations: 3     Fields:    Translation:AnimalsCells
  121. Leviton A, Allred EN, Kuban KC, Dammann O, Fichorova RN, O'Shea TM, Paneth N. Blood protein concentrations in the first two postnatal weeks associated with early postnatal blood gas derangements among infants born before the 28th week of gestation. The ELGAN Study. Cytokine. 2011 Nov; 56(2):392-8. PMID: 21821429.
    Citations: 9     Fields:    Translation:Humans
  122. Leviton A, Hecht JL, Allred EN, Yamamoto H, Fichorova RN, Dammann O. Persistence after birth of systemic inflammation associated with umbilical cord inflammation. J Reprod Immunol. 2011 Aug; 90(2):235-43. PMID: 21722967.
    Citations: 20     Fields:    Translation:HumansCTClinical Trials
  123. Faupel-Badger JM, Fichorova RN, Allred EN, Hecht JL, Dammann O, Leviton A, McElrath TF. Cluster analysis of placental inflammatory proteins can distinguish preeclampsia from preterm labor and premature membrane rupture in singleton deliveries less than 28 weeks of gestation. Am J Reprod Immunol. 2011 Dec; 66(6):488-94. PMID: 21623999.
    Citations: 7     Fields:    Translation:Humans
  124. Fichorova RN, Lai JJ, Schwartz JL, Weiner DH, Mauck CK, Callahan MM. Baseline variation and associations between subject characteristics and five cytokine biomarkers of vaginal safety among healthy non-pregnant women in microbicide trials. Cytokine. 2011 Jul; 55(1):134-40. PMID: 21530305.
    Citations: 13     Fields:    Translation:HumansCTClinical Trials
  125. Singh M, Kindelberger D, Nagymanyoki Z, Ng SW, Quick CM, Elias KM, Yamamoto H, Fichorova R, Fulop V, Berkowitz RS. Matrix metalloproteinases and their inhibitors and inducer in gestational trophoblastic diseases and normal placenta. Gynecol Oncol. 2011 Jul; 122(1):178-82. PMID: 21514631.
    Citations:    Fields:    Translation:Humans
  126. Bose C, Laughon M, Allred EN, Van Marter LJ, O'Shea TM, Ehrenkranz RA, Fichorova R, Leviton A. Blood protein concentrations in the first two postnatal weeks that predict bronchopulmonary dysplasia among infants born before the 28th week of gestation. Pediatr Res. 2011 Apr; 69(4):347-53. PMID: 21150694.
    Citations: 26     Fields:    Translation:Humans
  127. McElrath TF, Fichorova RN, Allred EN, Hecht JL, Ismail MA, Yuan H, Leviton A. Blood protein profiles of infants born before 28 weeks differ by pregnancy complication. Am J Obstet Gynecol. 2011 May; 204(5):418.e1-418.e12. PMID: 21349490.
    Citations: 38     Fields:    Translation:Humans
  128. Goodman RP, Freret TS, Kula T, Geller AM, Talkington MW, Tang-Fernandez V, Suciu O, Demidenko AA, Ghabrial SA, Beach DH, Singh BN, Fichorova RN, Nibert ML. Clinical isolates of Trichomonas vaginalis concurrently infected by strains of up to four Trichomonasvirus species (Family Totiviridae). J Virol. 2011 May; 85(9):4258-70. PMID: 21345965.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  129. Leviton A, Kuban KC, Allred EN, Fichorova RN, O'Shea TM, Paneth N. Early postnatal blood concentrations of inflammation-related proteins and microcephaly two years later in infants born before the 28th post-menstrual week. Early Hum Dev. 2011 May; 87(5):325-30. PMID: 21334149.
    Citations: 32     Fields:    Translation:Humans
  130. Fichorova RN, Onderdonk AB, Yamamoto H, Delaney ML, DuBois AM, Allred E, Leviton A. Maternal microbe-specific modulation of inflammatory response in extremely low-gestational-age newborns. mBio. 2011 Jan 18; 2(1):e00280-10. PMID: 21264056.
    Citations: 40     Fields:    Translation:HumansCells
  131. Leviton A, Kuban K, O'Shea TM, Paneth N, Fichorova R, Allred EN, Dammann O. The relationship between early concentrations of 25 blood proteins and cerebral white matter injury in preterm newborns: the ELGAN study. J Pediatr. 2011 Jun; 158(6):897-903.e1-5. PMID: 21238986.
    Citations: 52     Fields:    Translation:Humans
  132. Hecht JL, Fichorova RN, Tang VF, Allred EN, McElrath TF, Leviton A. Relationship Between Neonatal Blood Protein Concentrations and Placenta Histologic Characteristics in Extremely Low GA Newborns. Pediatr Res. 2011 Jan; 69(1):68-73. PMID: 20921924.
    Citations: 47     Fields:    Translation:Humans
  133. Goodman RP, Ghabrial SA, Fichorova RN, Nibert ML. Trichomonasvirus: a new genus of protozoan viruses in the family Totiviridae. Arch Virol. 2011 Jan; 156(1):171-9. PMID: 20976609.
    Citations: 16     Fields:    Translation:AnimalsCells
  134. Leviton A, Fichorova R, Yamamoto Y, Allred EN, Dammann O, Hecht J, Kuban K, McElrath T, O'Shea TM, Paneth N. Inflammation-related proteins in the blood of extremely low gestational age newborns. The contribution of inflammation to the appearance of developmental regulation. Cytokine. 2011 Jan; 53(1):66-73. PMID: 20934883.
    Citations: 36     Fields:    Translation:Humans
  135. Cramer DW, Vitonis AF, Pinheiro SP, McKolanis JR, Fichorova RN, Brown KE, Hatchette TF, Finn OJ. Mumps and ovarian cancer: modern interpretation of an historic association. Cancer Causes Control. 2010 Aug; 21(8):1193-201. PMID: 20559706.
    Citations: 16     Fields:    Translation:Humans
  136. Gadjeva M, Paradis-Bleau C, Priebe GP, Fichorova R, Pier GB. Caveolin-1 modifies the immunity to Pseudomonas aeruginosa. J Immunol. 2010 Jan 01; 184(1):296-302. PMID: 19949109.
    Citations: 20     Fields:    Translation:AnimalsCells
  137. Fichorova RN. Impact of T. vaginalis infection on innate immune responses and reproductive outcome. J Reprod Immunol. 2009 Dec; 83(1-2):185-9. PMID: 19850356.
    Citations: 59     Fields:    Translation:HumansAnimals
  138. Trifonova RT, Doncel GF, Fichorova RN. Polyanionic microbicides modify Toll-like receptor-mediated cervicovaginal immune responses. Antimicrob Agents Chemother. 2009 Apr; 53(4):1490-500. PMID: 19139286.
    Citations: 19     Fields:    Translation:HumansCells
  139. Fichorova, RN. Antiviral Research: Strategies in Antiviral Drug Discovery (LaFemina, Editor). Microbicides – molecular strategies for prevention of sexually transmitted viral disease. 2009; 265-282. View Publication.
  140. Mauck CK, Ballagh SA, Creinin MD, Weiner DH, Doncel GF, Fichorova RN, Schwartz JL, Chandra N, Callahan MM. Six-day randomized safety trial of intravaginal lime juice. J Acquir Immune Defic Syndr. 2008 Nov 01; 49(3):243-50. PMID: 18845958.
    Citations: 10     Fields:    Translation:HumansAnimals
  141. Singh BN, Hayes GR, Lucas JJ, Sommer U, Viseux N, Mirgorodskaya E, Trifonova RT, Sassi RR, Costello CE, Fichorova RN. Structural details and composition of Trichomonas vaginalis lipophosphoglycan in relevance to the epithelial immune function. Glycoconj J. 2009 Jan; 26(1):3-17. PMID: 18604640.
    Citations: 21     Fields:    Translation:HumansAnimalsCells
  142. Fichorova RN, Richardson-Harman N, Alfano M, Belec L, Carbonneil C, Chen S, Cosentino L, Curtis K, Dezzutti CS, Donoval B, Doncel GF, Donaghay M, Grivel JC, Guzman E, Hayes M, Herold B, Hillier S, Lackman-Smith C, Landay A, Margolis L, Mayer KH, Pasicznyk JM, Pallansch-Cokonis M, Poli G, Reichelderfer P, Roberts P, Rodriguez I, Saidi H, Sassi RR, Shattock R, Cummins JE. Biological and technical variables affecting immunoassay recovery of cytokines from human serum and simulated vaginal fluid: a multicenter study. Anal Chem. 2008 Jun 15; 80(12):4741-51. PMID: 18484740.
    Citations: 65     Fields:    Translation:Humans
  143. Singh BN, Lucas JJ and Fichorova RN. Emerging Protozoan Pathogens. Trichomonas vaginalis: Pathobiology and Pathogenesis (Khan, NA.; Jarrol, EL.,editors). 2008; 411-455. View Publication.
  144. Trifonova RT, Bajpai M, Pasicznyk JM, Chandra N, Doncel GF, Fichorova RN. Biomarkers of leukocyte traffic and activation in the vaginal mucosa. Biomarkers. 2007 Nov-Dec; 12(6):608-22. PMID: 17852080.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  145. Losikoff P, Fichorova R, Snyder B, Rodriguez I, Cu-Uvin S, Harwell J, Mayer KH. Genital tract interleukin-8 but not interleukin-1beta or interleukin-6 concentration is associated with bacterial vaginosis and its clearance in HIV-infected and HIV-uninfected women. Infect Dis Obstet Gynecol. 2007; 2007:92307. PMID: 18273408.
    Citations: 12     Fields:    Translation:HumansCells
  146. Trifonova RT, Pasicznyk JM, Fichorova RN. Biocompatibility of solid-dosage forms of anti-human immunodeficiency virus type 1 microbicides with the human cervicovaginal mucosa modeled ex vivo. Antimicrob Agents Chemother. 2006 Dec; 50(12):4005-10. PMID: 17030562.
    Citations: 16     Fields:    Translation:HumansCells
  147. Fichorova RN, Trifonova RT, Gilbert RO, Costello CE, Hayes GR, Lucas JJ, Singh BN. Trichomonas vaginalis lipophosphoglycan triggers a selective upregulation of cytokines by human female reproductive tract epithelial cells. Infect Immun. 2006 Oct; 74(10):5773-9. PMID: 16988255.
    Citations: 53     Fields:    Translation:HumansAnimalsCells
  148. Canny GO, Trifonova RT, Kindelberger DW, Colgan SP, Fichorova RN. Expression and function of bactericidal/permeability-increasing protein in human genital tract epithelial cells. J Infect Dis. 2006 Aug 15; 194(4):498-502. PMID: 16845634.
    Citations: 16     Fields:    Translation:HumansCells
  149. Schwartz JL, Mauck C, Lai JJ, Creinin MD, Brache V, Ballagh SA, Weiner DH, Hillier SL, Fichorova RN, Callahan M. Fourteen-day safety and acceptability study of 6% cellulose sulfate gel: a randomized double-blind Phase I safety study. Contraception. 2006 Aug; 74(2):133-40. PMID: 16860051.
    Citations: 33     Fields:    Translation:HumansCTClinical Trials
  150. Fichorova RN, Zhou F, Ratnam V, Atanassova V, Jiang S, Strick N, Neurath AR. Anti-human immunodeficiency virus type 1 microbicide cellulose acetate 1,2-benzenedicarboxylate in a human in vitro model of vaginal inflammation. Antimicrob Agents Chemother. 2005 Jan; 49(1):323-35. PMID: 15616312.
    Citations: 21     Fields:    Translation:HumansCells
  151. Doncel GF, Chandra N, Fichorova RN. Preclinical assessment of the proinflammatory potential of microbicide candidates. J Acquir Immune Defic Syndr. 2004 Oct; 37 Suppl 3:S174-80. PMID: 16419269.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  152. Gargiulo AR, Fichorova RN, Politch JA, Hill JA, Anderson DJ. Detection of implantation-related cytokines in cervicovaginal secretions and peripheral blood of fertile women during ovulatory menstrual cycles. Fertil Steril. 2004 Oct; 82 Suppl 3:1226-34. PMID: 15474100.
    Citations: 12     Fields:    Translation:Humans
  153. Fichorova RN. Guiding the vaginal microbicide trials with biomarkers of inflammation. J Acquir Immune Defic Syndr. 2004 Oct; 37 Suppl 3:S184-93. PMID: 16419271.
    Citations: 39     Fields:    Translation:Humans
  154. Fichorova RN, Bajpai M, Chandra N, Hsiu JG, Spangler M, Ratnam V, Doncel GF. Interleukin (IL)-1, IL-6, and IL-8 predict mucosal toxicity of vaginal microbicidal contraceptives. Biol Reprod. 2004 Sep; 71(3):761-9. PMID: 15128598.
    Citations: 59     Fields:    Translation:AnimalsCells
  155. Kleine-Lowinski K, Rheinwald JG, Fichorova RN, Anderson DJ, Basile J, Münger K, Daly CM, Rösl F, Rollins BJ. Selective suppression of monocyte chemoattractant protein-1 expression by human papillomavirus E6 and E7 oncoproteins in human cervical epithelial and epidermal cells. Int J Cancer. 2003 Nov 10; 107(3):407-15. PMID: 14506741.
    Citations: 18     Fields:    Translation:HumansCells
  156. Krebs FC, Miller SR, Catalone BJ, Fichorova R, Anderson D, Malamud D, Howett MK, Wigdahl B. Comparative in vitro sensitivities of human immune cell lines, vaginal and cervical epithelial cell lines, and primary cells to candidate microbicides nonoxynol 9, C31G, and sodium dodecyl sulfate. Antimicrob Agents Chemother. 2002 Jul; 46(7):2292-8. PMID: 12069993.
    Citations: 15     Fields:    Translation:HumansCells
  157. Fichorova RN, Cronin AO, Lien E, Anderson DJ, Ingalls RR. Response to Neisseria gonorrhoeae by cervicovaginal epithelial cells occurs in the absence of toll-like receptor 4-mediated signaling. J Immunol. 2002 Mar 01; 168(5):2424-32. PMID: 11859134.
    Citations: 78     Fields:    Translation:HumansCells
  158. Kalaydjiev SK, Dimitrova DK, Trifonova NL, Fichorova RN, Masharova NG, Raicheva YN, Simeonova MN, Todorova EI, Todorov VI, Nakov LS. The age-related changes in the incidence of 'natural' anti-sperm antibodies suggest they are not auto-/isoantibodies. Am J Reprod Immunol. 2002 Feb; 47(2):65-71. PMID: 11900590.
    Citations: 1     Fields:    Translation:HumansCells
  159. Fichorova RN, Desai PJ, Gibson FC, Genco CA. Distinct proinflammatory host responses to Neisseria gonorrhoeae infection in immortalized human cervical and vaginal epithelial cells. Infect Immun. 2001 Sep; 69(9):5840-8. PMID: 11500462.
    Citations: 62     Fields:    Translation:HumansCells
  160. Fichorova RN, Tucker LD, Anderson DJ. The molecular basis of nonoxynol-9-induced vaginal inflammation and its possible relevance to human immunodeficiency virus type 1 transmission. J Infect Dis. 2001 Aug 15; 184(4):418-28. PMID: 11471099.
    Citations: 93     Fields:    Translation:HumansCells
  161. Fichorova RN, Anderson DJ. Cytokines in the cervical vaginal environment. Cytokines in Reproduction. JA Hill, ed. 2000; 79-91.
  162. Fichorova RN, Anderson DJ. Differential expression of immunobiological mediators by immortalized human cervical and vaginal epithelial cells. Biol Reprod. 1999 Feb; 60(2):508-14. PMID: 9916021.
    Citations: 74     Fields:    Translation:HumansCells
  163. Dimitrova-Dikanarova DK, Marinova TT, Fichorova RN. Heterogeneity in the presence of CD4-like molecules on human spermatozoa. Andrologia. 1998 May-Jun; 30(3):147-51. PMID: 9635094.
    Citations: 1     Fields:    Translation:HumansCells
  164. Anderson DJ, Politch JA, Tucker LD, Fichorova R, Haimovici F, Tuomala RE, Mayer KH. Quantitation of mediators of inflammation and immunity in genital tract secretions and their relevance to HIV type 1 transmission. AIDS Res Hum Retroviruses. 1998 Apr; 14 Suppl 1:S43-9. PMID: 9581883.
    Citations: 18     Fields:    Translation:HumansCells
  165. Fichorova RN, Rheinwald JG, Anderson DJ. Generation of papillomavirus-immortalized cell lines from normal human ectocervical, endocervical, and vaginal epithelium that maintain expression of tissue-specific differentiation proteins. Biol Reprod. 1997 Oct; 57(4):847-55. PMID: 9314589.
    Citations: 119     Fields:    Translation:HumansCells
  166. Fichorova R, Nakov L, Baleva M, Nikolov K, Gegova I. Sperm, nuclear, phospholipid, and red blood cell antibodies and isotype RF in infertile couples and patients with autoimmune rheumatic diseases. Am J Reprod Immunol. 1996 Dec; 36(6):309-16. PMID: 8985506.
    Citations: 2     Fields:    Translation:HumansCells
  167. Fichorova RN, Boulanov ID. Anti-seminal plasma antibodies associated with infertility: I. Serum antibodies against normozoospermic seminal plasma in patients with unexplained infertility. Am J Reprod Immunol. 1996 Oct; 36(4):198-203. PMID: 8911626.
    Citations: 1     Fields:    Translation:Humans
  168. Fichorova R, Boulanov I, Stanislavov R. Anti-seminal plasma antibodies associated with infertility: II. Comparative investigation of human antibody binding to normo-, astheno-, and azoospermic seminal plasma antigens. Am J Reprod Immunol. 1996 Oct; 36(4):204-10. PMID: 8911627.
    Citations:    Fields:    Translation:Humans
  169. Fichorova R, Mavrov C, Mladenov I, Dimitrova E, Nakov L. A novel approach to the generation of antibodies against phylogenetically preserved sperm antigens. Theriogenology. 1996 Apr 01; 45(5):957-75. PMID: 16727856.
    Citations:    Fields:    
  170. Georgieva R, Stefanov D, Fichorova R, Dimitrova E. Effects of the whole extract and the chromatographic fractions of the pig placenta on lymphocyte proliferation and humoral immune response. Theriogenology. 1995 Sep; 44(4):539-51. PMID: 16727752.
    Citations: 2     Fields:    
  171. Fichorova RN, Dimitrova E, Nakov L, Tzvetkov D, Penkov R, Taskov H. Detection of antibodies toward epididymal sperm antigens--an obligatory step in evaluation of human immunologic infertility? Am J Reprod Immunol. 1995 May; 33(5):341-9. PMID: 7576115.
    Citations:    Fields:    Translation:HumansCells
  172. Belova N, Bojanovska V, Boulanov I, Vatev I, Gateva I, Garchev R, Dikanarova D, Koleva R, Kurtev A, Marinova Z, Marcholev L, Mitova L, Mladenov I, Pirjova B, Trifonova N, Uzunov V, Fichorova R. . Tests for Candidate-Students in Medicine, Pharmacy and Dental Medicine. I. Boulanov, ed. 1994.
  173. Fichorova RN, Nakov LS. The use of ELISA to evaluate human antibody binding to epididymal sperm from different species. Am J Reprod Immunol. 1993 Mar; 29(2):109-15. PMID: 8329103.
    Citations:    Fields:    Translation:HumansAnimalsCells
  174. Fichorova R, Anderson DJ. Use of sperm viability and acrosomal status assays in combination with immunofluorescence technique to ascertain surface expression of sperm antigens. J Reprod Immunol. 1991 May; 20(1):1-13. PMID: 1908520.
    Citations: 2     Fields:    Translation:HumansCells
  175. Fichorova R, Nakov L, Kiurkchiev S, Stanislavov R. [Cross reactivity of human auto- and iso-antispermatozoa sera with spermatozoa of the guinea pig, hamster and rat]. Eksp Med Morfol. 1988; 27(1):36-41. PMID: 3371241.
    Citations:    Fields:    Translation:HumansAnimalsCells
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