Harvard Catalyst Profiles

Broad Institute, Cambridge, Ma			Post-doctoral Fellow, Hacohen Lab
Brigham & Women's Hospital, Boston, Ma		2018	Rheumatology Fellowship
Brigham & Women's Hospital, Boston, Ma		2014	Internal Medicine Residency
Stanford School of Medicine, Stanford, Ca	MD, PhD	2012	Molec. & Cell Phys.
NIH, Bethesda, MD		2003	Fellow
Univ. of Arizona, Tucson, Az	BS	2002	Molec. & Cell Bio.

Dr. Paul Hoover is a physician-scientist in the Division of Rheumatology at the Brigham and Women’s Hospital with a clinical and research focus on lupus nephritis and related myeloid biology. As an Instructor he has worked at the Broad Institute in the Hacohen laboratory to develop a unique scientific program with the goal of understanding how myeloid cells drive tissue damage in lupus kidneys. His scientific program is composed of three major efforts: 1) identification of associations between novel myeloid states and gene programs with kidney lesions in clinical samples that can be experimentally tested; 2) utilization of lupus mouse models to test hypotheses from studying human samples; 3) identification of genetic drivers of myeloid differentiation, gene programs, and key functions in kidneys using CRISPR screens. Dr. Hoover earned his medical degree and doctorate in cellular physiology from Stanford University School of Medicine. He completed residency training and a fellowship in Rheumatology at Brigham and Women’s Hospital.