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Paolo Cassano, Ph.D., M.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Hamper M, Cassano P, Lombard J. Treatment of Kleine-Levin Syndrome With Intranasal Photobiomodulation and Methylene Blue. Cureus. 2021 Oct; 13(10):e18596. PMID: 34659921.
  2. Fisher LB, Tuchman S, Curreri A, Markgraf M, Nyer MB, Cassano P, Iverson G, Fava M, Zafonte R, Pedrelli P. Conducting Clinical Research Remotely for Individuals with Traumatic Brain Injury (TBI) and Depression during the COVID-19 Pandemic: Transitioning from In-Person to Remote Implementation. JMIR Form Res. 2021 Oct 05. PMID: 34662285.
  3. Stein MB, Jain S, Simon NM, West JC, Marvar PJ, Bui E, He F, Benedek DM, Cassano P, Griffith JL, Howlett J, Malgaroli M, Melaragno A, Seligowski AV, Shu IW, Song S, Szuhany K, Taylor CT, Ressler KJ. Randomized, Placebo-Controlled Trial of the Angiotensin Receptor Antagonist Losartan for Posttraumatic Stress Disorder. Biol Psychiatry. 2021 10 01; 90(7):473-481. PMID: 34275593.
    Citations:    Fields:    Translation:Humans
  4. Caldieraro MA, Laufer-Silva T, Cassano P. Dosimetry and Clinical Efficacy of Transcranial Photobiomodulation for Major Depression Disorder: Could they Guide Dosimetry for Alzheimer's Disease? J Alzheimers Dis. 2021; 83(4):1453-1469. PMID: 34487045.
    Citations:    Fields:    
  5. Spera V, Sitnikova T, Ward MJ, Farzam P, Hughes J, Gazecki S, Bui E, Maiello M, De Taboada L, Hamblin MR, Franceschini MA, Cassano P. Pilot Study on Dose-Dependent Effects of Transcranial Photobiomodulation on Brain Electrical Oscillations: A Potential Therapeutic Target in Alzheimer's Disease. J Alzheimers Dis. 2021; 83(4):1481-1498. PMID: 34092636.
    Citations:    Fields:    
  6. Dichtel LE, Carpenter LL, Nyer M, Mischoulon D, Kimball A, Deckersbach T, Dougherty DD, Schoenfeld DA, Fisher L, Cusin C, Dording C, Trinh NH, Pedrelli P, Yeung A, Farabaugh A, Papakostas GI, Chang T, Shapero BG, Chen J, Cassano P, Hahn EM, Rao EM, Brady RO, Singh RJ, Tyrka AR, Price LH, Fava M, Miller KK. Low-Dose Testosterone Augmentation for Antidepressant-Resistant Major Depressive Disorder in Women: An 8-Week Randomized Placebo-Controlled Study. Am J Psychiatry. 2020 10 01; 177(10):965-973. PMID: 32660299.
    Citations: 3     Fields:    Translation:Humans
  7. Salehpour F, Gholipour-Khalili S, Farajdokht F, Kamari F, Walski T, Hamblin MR, DiDuro JO, Cassano P. Therapeutic potential of intranasal photobiomodulation therapy for neurological and neuropsychiatric disorders: a narrative review. Rev Neurosci. 2020 Apr 28; 31(3):269-286. PMID: 31812948.
    Citations: 3     Fields:    Translation:Humans
  8. Yuan Y, Cassano P, Pias M, Fang Q. Transcranial photobiomodulation with near-infrared light from childhood to elderliness: simulation of dosimetry. Neurophotonics. 2020 Jan; 7(1):015009. PMID: 32118086.
    Citations: 1     
  9. Cassano P, Caldieraro MA, Norton R, Mischoulon D, Trinh NH, Nyer M, Dording C, Hamblin MR, Campbell B, Iosifescu DV. Reported Side Effects, Weight and Blood Pressure, After Repeated Sessions of Transcranial Photobiomodulation. Photobiomodul Photomed Laser Surg. 2019 Oct; 37(10):651-656. PMID: 31647774.
    Citations: 4     Fields:    Translation:Humans
  10. Maiello M, Losiewicz OM, Bui E, Spera V, Hamblin MR, Marques L, Cassano P. Transcranial Photobiomodulation with Near-Infrared Light for Generalized Anxiety Disorder: A Pilot Study. Photobiomodul Photomed Laser Surg. 2019 Oct; 37(10):644-650. PMID: 31647775.
    Citations: 1     Fields:    Translation:HumansCTClinical Trials
  11. Salehpour F, Cassano P, Rouhi N, Hamblin MR, De Taboada L, Farajdokht F, Mahmoudi J. Penetration Profiles of Visible and Near-Infrared Lasers and Light-Emitting Diode Light Through the Head Tissues in Animal and Human Species: A Review of Literature. Photobiomodul Photomed Laser Surg. 2019 Oct; 37(10):581-595. PMID: 31553265.
    Citations: 7     Fields:    Translation:HumansAnimals
  12. Cassano P. Photomedicine and Pharmaceuticals: A Brain New Deal. Photobiomodul Photomed Laser Surg. 2019 Oct; 37(10):575-576. PMID: 31549918.
    Citations: 2     Fields:    Translation:Humans
  13. Salehpour F, Majdi A, Pazhuhi M, Ghasemi F, Khademi M, Pashazadeh F, Hamblin MR, Cassano P. Transcranial Photobiomodulation Improves Cognitive Performance in Young Healthy Adults: A Systematic Review and Meta-Analysis. Photobiomodul Photomed Laser Surg. 2019 Oct; 37(10):635-643. PMID: 31549906.
    Citations: 1     Fields:    Translation:Humans
  14. Mannu P, Maiello M, Spera V, Cassano P. Transcranial Photobiomodulation for Down Syndrome. Photobiomodul Photomed Laser Surg. 2019 Oct; 37(10):579-580. PMID: 31536469.
    Citations:    Fields:    Translation:Humans
  15. Mannu P, Saccaro LF, Spera V, Cassano P. Transcranial Photobiomodulation to Augment Lithium in Bipolar-I Disorder. Photobiomodul Photomed Laser Surg. 2019 Oct; 37(10):577-578. PMID: 31532306.
    Citations:    Fields:    Translation:Humans
  16. Cassano P, Tran AP, Katnani H, Bleier BS, Hamblin MR, Yuan Y, Fang Q. Selective photobiomodulation for emotion regulation: model-based dosimetry study. Neurophotonics. 2019 Jan; 6(1):015004. PMID: 30796882.
    Citations: 11     
  17. Salehpour F, De Taboada L, Cassano P, Kamari F, Mahmoudi J, Ahmadi-Kandjani S, Rasta SH, Sadigh-Eteghad S. A Protocol for Transcranial Photobiomodulation Therapy in Mice. J Vis Exp. 2018 11 18; (141). PMID: 30507909.
    Citations: 2     Fields:    Translation:Animals
  18. Pedrelli P, MacPherson L, Khan AJ, Shapero BG, Fisher LB, Nyer M, Cassano P, Parnarouskis L, Farabaugh A, Fava M, Silveri MM. Sex Differences in the Association between Heavy Drinking and Behavioral Distress Tolerance and Emotional Reactivity Among Non-Depressed College Students. Alcohol Alcohol. 2018 Nov 01; 53(6):674-681. PMID: 29947730.
    Citations: 1     Fields:    Translation:Humans
  19. Salehpour F, Farajdokht F, Cassano P, Sadigh-Eteghad S, Erfani M, Hamblin MR, Salimi MM, Karimi P, Rasta SH, Mahmoudi J. Near-infrared photobiomodulation combined with coenzyme Q10 for depression in a mouse model of restraint stress: reduction in oxidative stress, neuroinflammation, and apoptosis. Brain Res Bull. 2019 01; 144:213-222. PMID: 30385146.
    Citations: 18     Fields:    Translation:Animals
  20. Cassano P, Petrie SR, Mischoulon D, Cusin C, Katnani H, Yeung A, De Taboada L, Archibald A, Bui E, Baer L, Chang T, Chen J, Pedrelli P, Fisher L, Farabaugh A, Hamblin MR, Alpert JE, Fava M, Iosifescu DV. Transcranial Photobiomodulation for the Treatment of Major Depressive Disorder. The ELATED-2 Pilot Trial. Photomed Laser Surg. 2018 Dec; 36(12):634-646. PMID: 30346890.
    Citations: 10     Fields:    Translation:Humans
  21. Gabel CP, Petrie SR, Mischoulon D, Hamblin MR, Yeung A, Sangermano L, Cassano P. A case control series for the effect of photobiomodulation in patients with low back pain and concurrent depression. Laser Ther. 2018 Sep 30; 27(3):167-173. PMID: 32158062.
  22. Cassano P, Dording C, Thomas G, Foster S, Yeung A, Uchida M, Hamblin MR, Bui E, Fava M, Mischoulon D, Iosifescu DV. Effects of transcranial photobiomodulation with near-infrared light on sexual dysfunction. Lasers Surg Med. 2019 02; 51(2):127-135. PMID: 30221776.
    Citations: 3     Fields:    Translation:Humans
  23. Caldieraro MA, Cassano P. Transcranial and systemic photobiomodulation for major depressive disorder: A systematic review of efficacy, tolerability and biological mechanisms. J Affect Disord. 2019 01 15; 243:262-273. PMID: 30248638.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  24. Caldieraro MA, Sani G, Bui E, Cassano P. Long-Term Near-Infrared Photobiomodulation for Anxious Depression Complicated by Takotsubo Cardiomyopathy. J Clin Psychopharmacol. 2018 06; 38(3):268-270. PMID: 29601319.
    Citations: 9     Fields:    Translation:Humans
  25. Curren L, Huz I, McKee M, Traeger L, Bedoya CA, Chang TE, Cassano P, Fava M, Alpert J, Yeung A, Gilman SE, Trinh NH. Patient primary language in a culturally focused intervention for Latino Americans with depression. Ann Clin Psychiatry. 2018 05; 30(2):84-90. PMID: 29697708.
    Citations: 1     Fields:    Translation:Humans
  26. Vance MC, Bui E, Hoeppner SS, Kovachy B, Prescott J, Mischoulon D, Walton ZE, Dong M, Nadal MF, Worthington JJ, Hoge EA, Cassano P, Orr EH, Fava M, de Vivo I, Wong KK, Simon NM. Prospective association between major depressive disorder and leukocyte telomere length over two years. Psychoneuroendocrinology. 2018 04; 90:157-164. PMID: 29499556.
    Citations: 8     Fields:    Translation:HumansCells
  27. Cusin C, Ionescu DF, Pavone KJ, Akeju O, Cassano P, Taylor N, Eikermann M, Durham K, Swee MB, Chang T, Dording C, Soskin D, Kelley J, Mischoulon D, Brown EN, Fava M. Ketamine augmentation for outpatients with treatment-resistant depression: Preliminary evidence for two-step intravenous dose escalation. Aust N Z J Psychiatry. 2017 Jan; 51(1):55-64. PMID: 26893373.
    Citations: 18     Fields:    Translation:Humans
  28. Cassano P, Bui E, Rogers AH, Walton ZE, Ross R, Zeng M, Nadal-Vicens M, Mischoulon D, Baker AW, Keshaviah A, Worthington J, Hoge EA, Alpert J, Fava M, Wong KK, Simon NM. Inflammatory cytokines in major depressive disorder: A case-control study. Aust N Z J Psychiatry. 2017 Jan; 51(1):23-31. PMID: 27313138.
    Citations: 15     Fields:    Translation:Humans
  29. Ionescu DF, Swee MB, Pavone KJ, Taylor N, Akeju O, Baer L, Nyer M, Cassano P, Mischoulon D, Alpert JE, Brown EN, Nock MK, Fava M, Cusin C. Rapid and Sustained Reductions in Current Suicidal Ideation Following Repeated Doses of Intravenous Ketamine: Secondary Analysis of an Open-Label Study. J Clin Psychiatry. 2016 06; 77(6):e719-25. PMID: 27232360.
    Citations: 25     Fields:    Translation:Humans
  30. Cassano P, Petrie SR, Hamblin MR, Henderson TA, Iosifescu DV. Review of transcranial photobiomodulation for major depressive disorder: targeting brain metabolism, inflammation, oxidative stress, and neurogenesis. Neurophotonics. 2016 Jul; 3(3):031404. PMID: 26989758.
    Citations: 31     
  31. Cassano P, Trinh NH, Chang T, Cusin C, Fisher L, Pedrelli P, Nyer M, Kim DJ, Alpert J, Mischoulon D. Treatment Outcome in Depressed Latinos Predicted by Concomitant Psychosislike Symptoms. J Nerv Ment Dis. 2015 Oct; 203(10):769-73. PMID: 26356091.
    Citations:    Fields:    Translation:Humans
  32. Morries LD, Cassano P, Henderson TA. Treatments for traumatic brain injury with emphasis on transcranial near-infrared laser phototherapy. Neuropsychiatr Dis Treat. 2015; 11:2159-75. PMID: 26347062.
    Citations: 41     
  33. Cassano P, Cusin C, Mischoulon D, Hamblin MR, De Taboada L, Pisoni A, Chang T, Yeung A, Ionescu DF, Petrie SR, Nierenberg AA, Fava M, Iosifescu DV. Near-Infrared Transcranial Radiation for Major Depressive Disorder: Proof of Concept Study. Psychiatry J. 2015; 2015:352979. PMID: 26356811.
    Citations: 21     
  34. Cassano P, Chang T, Trinh NH, Baer L, Fava M, Mischoulon D. Differential impact of isolated psychotic symptoms on treatment outcome of major depressive disorder in the STAR*D cohort of Whites, Blacks and Latinos. J Affect Disord. 2013 Sep 05; 150(2):578-84. PMID: 23489398.
    Citations: 4     Fields:    Translation:Humans
  35. Cassano P, Fava M, Mischoulon D. Major depressive disorder with psychosis-like symptoms among Latinos. Psychiatr Serv. 2012; 63(5):482-7. PMID: 22422016.
    Citations: 3     Fields:    Translation:Humans
  36. Bentley AR, Raiszadeh F, Stover PJ, Hunter DJ, Hankinson SE, Cassano PA. No association between cSHMT genotypes and the risk of breast cancer in the Nurses' Health Study. Eur J Clin Nutr. 2010 Jan; 64(1):108-10. PMID: 19707223.
    Citations: 10     Fields:    Translation:Humans
  37. Galderisi S, Quarantelli M, Volpe U, Mucci A, Cassano GB, Invernizzi G, Rossi A, Vita A, Pini S, Cassano P, Daneluzzo E, De Peri L, Stratta P, Brunetti A, Maj M. Patterns of structural MRI abnormalities in deficit and nondeficit schizophrenia. Schizophr Bull. 2008 Mar; 34(2):393-401. PMID: 17728266.
    Citations: 31     Fields:    Translation:Humans
  38. Iosifescu DV, Renshaw PF, Dougherty DD, Lyoo IK, Lee HK, Fraguas R, Cassano P, Nierenberg AA, Fava M. Major depressive disorder with anger attacks and subcortical MRI white matter hyperintensities. J Nerv Ment Dis. 2007 Feb; 195(2):175-8. PMID: 17299307.
    Citations: 9     Fields:    Translation:Humans
  39. Soares CN, Arsenio H, Joffe H, Bankier B, Cassano P, Petrillo LF, Cohen LS. Escitalopram versus ethinyl estradiol and norethindrone acetate for symptomatic peri- and postmenopausal women: impact on depression, vasomotor symptoms, sleep, and quality of life. Menopause. 2006 Sep-Oct; 13(5):780-6. PMID: 16894334.
    Citations: 33     Fields:    Translation:Humans
  40. Davis LL, Frazier E, Husain MM, Warden D, Trivedi M, Fava M, Cassano P, McGrath PJ, Balasubramani GK, Wisniewski SR, Rush AJ. Substance use disorder comorbidity in major depressive disorder: a confirmatory analysis of the STAR*D cohort. Am J Addict. 2006 Jul-Aug; 15(4):278-85. PMID: 16867922.
    Citations: 28     Fields:    Translation:Humans
  41. Galderisi S, Maj M, Kirkpatrick B, Piccardi P, Mucci A, Invernizzi G, Rossi A, Pini S, Vita A, Cassano P, Stratta P, Severino G, Del Zompo M. Catechol-O-methyltransferase Val158Met polymorphism in schizophrenia: associations with cognitive and motor impairment. Neuropsychobiology. 2005; 52(2):83-9. PMID: 16037677.
    Citations: 15     Fields:    Translation:Humans
  42. Cassano P, Lattanzi L, Fava M, Navari S, Battistini G, Abelli M, Cassano GB. Ropinirole in treatment-resistant depression: a 16-week pilot study. Can J Psychiatry. 2005 May; 50(6):357-60. PMID: 15999953.
    Citations: 20     Fields:    Translation:HumansCTClinical Trials
  43. Tossani E, Cassano P, Fava M. Depression and renal disease. Semin Dial. 2005 Mar-Apr; 18(2):73-81. PMID: 15771649.
    Citations: 10     Fields:    Translation:Humans
  44. Davis LL, Rush JA, Wisniewski SR, Rice K, Cassano P, Jewell ME, Biggs MM, Shores-Wilson K, Balasubramani GK, Husain MM, Quitkin FM, McGrath PJ. Substance use disorder comorbidity in major depressive disorder: an exploratory analysis of the Sequenced Treatment Alternatives to Relieve Depression cohort. Compr Psychiatry. 2005 Mar-Apr; 46(2):81-9. PMID: 15723023.
    Citations: 23     Fields:    Translation:HumansCTClinical Trials
  45. Galderisi S, Maj M, Kirkpatrick B, Piccardi P, Mucci A, Invernizzi G, Rossi A, Pini S, Vita A, Cassano P, Stratta P, Severino G, Del Zompo M. COMT Val(158)Met and BDNF C(270)T polymorphisms in schizophrenia: a case-control study. Schizophr Res. 2005 Feb 01; 73(1):27-30. PMID: 15567073.
    Citations: 6     Fields:    Translation:Humans
  46. Cassano P, Soares CN, Cusin C, Mascarini A, Cohen LS, Fava M. Antidepressant response and well-being in pre-, peri- and postmenopausal women with major depressive disorder treated with fluoxetine. Psychother Psychosom. 2005; 74(6):362-5. PMID: 16244512.
    Citations: 6     Fields:    Translation:HumansCTClinical Trials
  47. Cohen LS, Soares CN, Lyster A, Cassano P, Brandes M, Leblanc GA. Efficacy and tolerability of premenstrual use of venlafaxine (flexible dose) in the treatment of premenstrual dysphoric disorder. J Clin Psychopharmacol. 2004 Oct; 24(5):540-3. PMID: 15349012.
    Citations: 7     Fields:    Translation:HumansCTClinical Trials
  48. Cassano P, Soares CN, Cohen LS, Lyster AK, Fava M. Sex- and age-related differences in major depressive disorder with comorbid anxiety treated with fluoxetine. Arch Womens Ment Health. 2004 Jul; 7(3):167-71. PMID: 15241662.
    Citations: 2     Fields:    Translation:HumansCTClinical Trials
  49. Cassano P, Lattanzi L, Soldani F, Navari S, Battistini G, Gemignani A, Cassano GB. Pramipexole in treatment-resistant depression: an extended follow-up. Depress Anxiety. 2004; 20(3):131-8. PMID: 15549689.
    Citations: 26     Fields:    Translation:HumansCTClinical Trials
  50. Cassano P, Fava M. Tolerability issues during long-term treatment with antidepressants. Ann Clin Psychiatry. 2004 Jan-Mar; 16(1):15-25. PMID: 15147109.
    Citations: 37     Fields:    Translation:Humans
  51. Pini S, Amador XF, Dell'Osso L, Baldini Rossi N, Cassano P, Savino M, Cassano GB. Treatment of depression with comorbid anxiety disorders: differential efficacy of paroxetine versus moclobemide. Int Clin Psychopharmacol. 2003 Jan; 18(1):15-21. PMID: 12490770.
    Citations: 1     Fields:    Translation:HumansCTClinical Trials
  52. Lattanzi L, Dell'Osso L, Cassano P, Pini S, Rucci P, Houck PR, Gemignani A, Battistini G, Bassi A, Abelli M, Cassano GB. Pramipexole in treatment-resistant depression: a 16-week naturalistic study. Bipolar Disord. 2002 Oct; 4(5):307-14. PMID: 12479663.
    Citations: 30     Fields:    Translation:HumansCTClinical Trials
  53. Cassano P, Fava M. Depression and public health: an overview. J Psychosom Res. 2002 Oct; 53(4):849-57. PMID: 12377293.
    Citations: 116     Fields:    Translation:HumansPHPublic Health
  54. Hu G, Zhang X, Chen J, Peto R, Campbell TC, Cassano PA. Dietary vitamin C intake and lung function in rural China. Am J Epidemiol. 1998 Sep 15; 148(6):594-9. PMID: 9753014.
    Citations: 24     Fields:    Translation:Humans
  55. Parker DR, Weiss ST, Troisi R, Cassano PA, Vokonas PS, Landsberg L. Relationship of dietary saturated fatty acids and body habitus to serum insulin concentrations: the Normative Aging Study. Am J Clin Nutr. 1993 Aug; 58(2):129-36. PMID: 8338037.
    Citations: 25     Fields:    Translation:Humans
  56. Cassano PA, Rosner B, Vokonas PS, Weiss ST. Obesity and body fat distribution in relation to the incidence of non-insulin-dependent diabetes mellitus. A prospective cohort study of men in the normative aging study. Am J Epidemiol. 1992 Dec 15; 136(12):1474-86. PMID: 1288277.
    Citations: 28     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.