"Genes, Tumor Suppressor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Genes that inhibit expression of the tumorigenic phenotype. They are normally involved in holding cellular growth in check. When tumor suppressor genes are inactivated or lost, a barrier to normal proliferation is removed and unregulated growth is possible.
MeSH Number(s)
G05.360.340.024.340.375.249
G05.360.340.024.340.415.400
Concept/Terms
Genes, Tumor Suppressor- Genes, Tumor Suppressor
- Gene, Tumor Suppressor
- Tumor Suppressor Gene
- Emerogenes
- Emerogene
- Genes, Onco-Suppressor
- Gene, Onco-Suppressor
- Genes, Onco Suppressor
- Onco-Suppressor Gene
- Onco-Suppressor Genes
- Tumor Suppressor Genes
- Genes, Cancer Suppressor
- Antioncogenes
- Antioncogene
- Anti-Oncogenes
- Anti Oncogenes
- Anti-Oncogene
- Tumor Suppressing Genes
- Gene, Tumor Suppressing
- Genes, Tumor Suppressing
- Tumor Suppressing Gene
- Cancer Suppressor Genes
- Cancer Suppressor Gene
- Gene, Cancer Suppressor
- Suppressor Gene, Cancer
- Suppressor Genes, Cancer
- Oncogenes, Recessive
- Oncogene, Recessive
- Recessive Oncogene
- Recessive Oncogenes
Metastasis Suppressor Genes- Metastasis Suppressor Genes
- Gene, Metastasis Suppressor
- Metastasis Suppressor Gene
- Suppressor Gene, Metastasis
- Suppressor Genes, Metastasis
- Genes, Metastasis Suppressor
Growth Suppressor Genes- Growth Suppressor Genes
- Gene, Growth Suppressor
- Growth Suppressor Gene
- Suppressor Gene, Growth
- Suppressor Genes, Growth
- Genes, Growth Suppressor
Below are MeSH descriptors whose meaning is more general than "Genes, Tumor Suppressor".
Below are MeSH descriptors whose meaning is more specific than "Genes, Tumor Suppressor".
- Genes, Tumor Suppressor
- Genes, APC
- Genes, BRCA1
- Genes, BRCA2
- Genes, DCC
- Genes, MCC
- Genes, Neurofibromatosis 1
- Genes, Neurofibromatosis 2
- Genes, p16
- Genes, p53
- Genes, Retinoblastoma
- Genes, Wilms Tumor
This graph shows the total number of publications written about "Genes, Tumor Suppressor" by people in Harvard Catalyst Profiles by year, and whether "Genes, Tumor Suppressor" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 5 | 4 | 9 |
| 1994 | 10 | 3 | 13 |
| 1995 | 16 | 9 | 25 |
| 1996 | 20 | 7 | 27 |
| 1997 | 19 | 18 | 37 |
| 1998 | 24 | 17 | 41 |
| 1999 | 16 | 16 | 32 |
| 2000 | 17 | 20 | 37 |
| 2001 | 17 | 19 | 36 |
| 2002 | 14 | 28 | 42 |
| 2003 | 9 | 26 | 35 |
| 2004 | 12 | 21 | 33 |
| 2005 | 16 | 15 | 31 |
| 2006 | 11 | 12 | 23 |
| 2007 | 7 | 7 | 14 |
| 2008 | 13 | 9 | 22 |
| 2009 | 13 | 5 | 18 |
| 2010 | 9 | 12 | 21 |
| 2011 | 13 | 12 | 25 |
| 2012 | 11 | 21 | 32 |
| 2013 | 13 | 7 | 20 |
| 2014 | 7 | 8 | 15 |
| 2015 | 2 | 12 | 14 |
| 2016 | 6 | 11 | 17 |
| 2017 | 5 | 6 | 11 |
| 2018 | 9 | 9 | 18 |
| 2019 | 9 | 5 | 14 |
| 2020 | 5 | 14 | 19 |
| 2021 | 5 | 9 | 14 |
| 2022 | 3 | 5 | 8 |
| 2023 | 0 | 1 | 1 |
Below are the most recent publications written about "Genes, Tumor Suppressor" by people in Profiles.
-
Cellular mechanisms of heterogeneity in NF2-mutant schwannoma. Nat Commun. 2023 Mar 21; 14(1):1559.
-
Setd2 inactivation sensitizes lung adenocarcinoma to inhibitors of oxidative respiration and mTORC1 signaling. Commun Biol. 2023 03 10; 6(1):255.
-
Loss of tumor suppressor WWOX accelerates pancreatic cancer development through promotion of TGFß/BMP2 signaling. Cell Death Dis. 2022 12 27; 13(12):1074.
-
To Rb or Not to Rb: Uncovering Unique Subsets of Small Cell Lung Carcinoma. Clin Cancer Res. 2022 11 01; 28(21):4603-4605.
-
Mosaicism in Tumor Suppressor Gene Syndromes: Prevalence, Diagnostic Strategies, and Transmission Risk. Annu Rev Genomics Hum Genet. 2022 08 31; 23:331-361.
-
Skin Aging in Long-Lived Naked Mole-Rats Is Accompanied by Increased Expression of Longevity-Associated and Tumor Suppressor Genes. J Invest Dermatol. 2022 11; 142(11):2853-2863.e4.
-
ISL2 is a putative tumor suppressor whose epigenetic silencing reprograms the metabolism of pancreatic cancer. Dev Cell. 2022 06 06; 57(11):1331-1346.e9.
-
Zac1 and the Imprinted Gene Network program juvenile NAFLD in response to maternal metabolic syndrome. Hepatology. 2022 10; 76(4):1090-1104.
-
Exploiting the tumor-suppressive activity of the androgen receptor by CDK4/6 inhibition in castration-resistant prostate cancer. Mol Ther. 2022 04 06; 30(4):1628-1644.
-
The metabolic stress-activated checkpoint LKB1-MARK3 axis acts as a tumor suppressor in high-grade serous ovarian carcinoma. Commun Biol. 2022 01 11; 5(1):39.