Genes, Retinoblastoma

"Genes, Retinoblastoma" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Tumor suppressor genes located on human chromosome 13 in the region 13q14 and coding for a family of phosphoproteins with molecular weights ranging from 104 kDa to 115 kDa. One copy of the wild-type Rb gene is necessary for normal retinal development. Loss or inactivation of both alleles at this locus results in retinoblastoma.

Descriptor ID

D016161

MeSH Number(s)

G05.360.340.024.340.375.249.400

G05.360.340.024.340.415.400.400

Concept/Terms

Genes, Retinoblastoma

Below are MeSH descriptors whose meaning is more general than "Genes, Retinoblastoma".

Biological Sciences [G]
Genetic Phenomena [G05]
Genetic Structures [G05.360]
Genome [G05.360.340]
Genome Components [G05.360.340.024]
Genes [G05.360.340.024.340]
Genes, Neoplasm [G05.360.340.024.340.375]
Genes, Tumor Suppressor [G05.360.340.024.340.375.249]
Genes, Retinoblastoma [G05.360.340.024.340.375.249.400]
Genes, Recessive [G05.360.340.024.340.415]
Genes, Tumor Suppressor [G05.360.340.024.340.415.400]
Genes, Retinoblastoma [G05.360.340.024.340.415.400.400]

Below are MeSH descriptors whose meaning is related to "Genes, Retinoblastoma".

Below are MeSH descriptors whose meaning is more specific than "Genes, Retinoblastoma".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Genes, Retinoblastoma" by people in Harvard Catalyst Profiles by year, and whether "Genes, Retinoblastoma" was a major or minor topic of these publication.

Bar chart showing 71 publications over 21 distinct years, with a maximum of 12 publications in 1994

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	8	4	12
1995	4	1	5
1996	4	4	8
1997	5	2	7
1998	4	1	5
1999	0	1	1
2000	1	0	1
2001	2	2	4
2002	3	0	3
2003	1	0	1
2004	0	1	1
2005	0	3	3
2006	1	3	4
2007	0	1	1
2009	0	3	3
2011	1	0	1
2012	1	2	3
2014	2	0	2
2015	1	2	3
2018	1	1	2
2019	0	1	1

Below are the most recent publications written about "Genes, Retinoblastoma" by people in Profiles.

Retinoblastoma Loss in Cancer: Casting a Wider Net. Clin Cancer Res. 2019 07 15; 25(14):4199-4201.

View in: PubMed
Autochthonous tumors driven by Rb1 loss have an ongoing requirement for the RBP2 histone demethylase. Proc Natl Acad Sci U S A. 2018 04 17; 115(16):E3741-E3748.

View in: PubMed
A gene expression signature of Retinoblastoma loss-of-function predicts resistance to neoadjuvant chemotherapy in ER-positive/HER2-positive breast cancer patients. Breast Cancer Res Treat. 2018 Jul; 170(2):329-341.

View in: PubMed
Evolution of telomere maintenance and tumour suppressor mechanisms across mammals. Philos Trans R Soc Lond B Biol Sci. 2018 03 05; 373(1741).

View in: PubMed
HBeAg-induced miR-106b promotes cell growth by targeting the retinoblastoma gene. Sci Rep. 2017 10 30; 7(1):14371.

View in: PubMed
Recombinase-based conditional and reversible gene regulation via XTR alleles. Nat Commun. 2015 Nov 05; 6:8783.

View in: PubMed
Retinoblastoma. Pediatr Clin North Am. 2015 Feb; 62(1):201-23.

View in: PubMed
Genetics and epigenetics of human retinoblastoma. Annu Rev Pathol. 2015; 10:547-62.

View in: PubMed
A combination of transcriptional and microRNA regulation improves the stability of the relative concentrations of target genes. PLoS Comput Biol. 2014 Feb; 10(2):e1003490.

View in: PubMed
Synchronous small bowel and atypical primary leiomyosarcoma of inferior vena cava in a patient with RB1 mutation. Abdom Imaging. 2014 Feb; 39(1):33-9.

View in: PubMed

Related Networks

People

Explore

Similar Concepts

Top Journals

Oncogene
Proc Natl Acad Sci U S A
Cancer Res
Nature
Mol Cell Biol
Genes Dev
J Clin Invest
J Clin Endocrinol Metab
Cancer Genet Cytogenet
Am J Hum Genet