Gene Knockdown Techniques
"Gene Knockdown Techniques" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The artificial induction of GENE SILENCING by the use of RNA INTERFERENCE to reduce the expression of a specific gene. It includes the use of DOUBLE-STRANDED RNA, such as SMALL INTERFERING RNA and RNA containing HAIRPIN LOOP SEQUENCE, and ANTI-SENSE OLIGONUCLEOTIDES.
Concept/Terms
Gene Knockdown Techniques- Gene Knockdown Techniques
- Gene Knockdown Technique
- Knockdown Technique, Gene
- Knockdown Techniques, Gene
- Technique, Gene Knockdown
- Techniques, Gene Knockdown
- Gene Knockdown
- Gene Knockdowns
- Knockdown, Gene
- Knockdowns, Gene
- Gene Knock-Down
- Gene Knock-Downs
- Knock-Down, Gene
- Knock-Downs, Gene
- Gene Knock-Down Techniques
- Gene Knock-Down Technique
- Knock-Down Technique, Gene
- Knock-Down Techniques, Gene
- Technique, Gene Knock-Down
- Techniques, Gene Knock-Down
- Gene Knock Down
- Gene Knock Downs
- Knock Down, Gene
- Knock Downs, Gene
- Gene Knock Down Techniques
Below are MeSH descriptors whose meaning is more general than "Gene Knockdown Techniques".
Below are MeSH descriptors whose meaning is more specific than "Gene Knockdown Techniques".
This graph shows the total number of publications written about "Gene Knockdown Techniques" by people in Harvard Catalyst Profiles by year, and whether "Gene Knockdown Techniques" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 9 | 9 |
| 2009 | 5 | 48 | 53 |
| 2010 | 3 | 66 | 69 |
| 2011 | 3 | 94 | 97 |
| 2012 | 1 | 104 | 105 |
| 2013 | 4 | 100 | 104 |
| 2014 | 2 | 103 | 105 |
| 2015 | 4 | 87 | 91 |
| 2016 | 4 | 91 | 95 |
| 2017 | 6 | 72 | 78 |
| 2018 | 3 | 57 | 60 |
| 2019 | 1 | 59 | 60 |
| 2020 | 1 | 44 | 45 |
| 2021 | 2 | 37 | 39 |
| 2022 | 1 | 6 | 7 |
Below are the most recent publications written about "Gene Knockdown Techniques" by people in Profiles.
-
CRISPR screens in Drosophila cells identify Vsg as a Tc toxin receptor. Nature. 2022 10; 610(7931):349-355.
-
Cingulin binds to the ZU5 domain of scaffolding protein ZO-1 to promote its extended conformation, stabilization, and tight junction accumulation. J Biol Chem. 2022 04; 298(4):101797.
-
Suppression of fibrin(ogen)-driven pathologies in disease models through controlled knockdown by lipid nanoparticle delivery of siRNA. Blood. 2022 03 03; 139(9):1302-1311.
-
SHMT2 inhibition disrupts the TCF3 transcriptional survival program in Burkitt lymphoma. Blood. 2022 01 27; 139(4):538-553.
-
Systematic mapping of rRNA 2'-O methylation during frog development and involvement of the methyltransferase Fibrillarin in eye and craniofacial development in Xenopus laevis. PLoS Genet. 2022 01; 18(1):e1010012.
-
A bidirectional competitive interaction between circHomer1 and Homer1b within the orbitofrontal cortex regulates reversal learning. Cell Rep. 2022 01 18; 38(3):110282.
-
Deficiency of lncRNA SNHG12 impairs ischemic limb neovascularization by altering an endothelial cell cycle pathway. JCI Insight. 2022 01 11; 7(1).
-
MLL1 is regulated by KSHV LANA and is important for virus latency. Nucleic Acids Res. 2021 12 16; 49(22):12895-12911.
-
RB depletion is required for the continuous growth of tumors initiated by loss of RB. PLoS Genet. 2021 12; 17(12):e1009941.
-
Methionine synthase is essential for cancer cell proliferation in physiological folate environments. Nat Metab. 2021 11; 3(11):1500-1511.