Harvard Catalyst Profiles

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Lynn Bry, M.D.,Ph.D.

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Biography
education and training
Cornell University, Ithaca, NYBAGenetics and Development; Mathematics
Washington University Medical School, St. Louis, MOMDMedicine
Washington University Medical School, St. Louis, MOPhDMolecular Microbiology and Pathogenesis
Brigham & Women's Hospital, Boston, MAFCAPClinical Pathology
HHMI Fellow, Lymphocyte Biology Section, Boston, MAMucosal Immunology
awards and honors
2000
Webby Awards Nominee in Science
2001
AACC Young Investigator Award
2007
Harvard Medical School Mentoring Award
2010
First place - HBS new ventures competition (iSpecimen)
2012
Soma Weiss Research Mentorship Award
2016
Innovations Development Award
2018
Mentorship award, Project Success
2018
Research leadership award
2021
Fellow American Academy of Microbiology

Overview
overview
Research:
Systems biology of host-commensal-pathogen interactions
Metabolic modeling of obligate anaerobe metabolism
Immunomodulatory properties of gut commensals
Genomically-informed pathogen surveillance for clinical and population health

Innovation/Platform technologies:
I direct the Massachusetts Host-Microbiome Center which provides integrated gnotobiotic, microbiologic, molecular/metabolomic and computational resources to support studies in how the microbiota influences our health and disease. We have supported >100 groups in the greater Boston area and beyond.
I also developed the Crimson prospective collection and patient recruitment system that supports >200 clinical studies among Boston-based institutions and with other collaborators in the US and abroad.
Startups: Cognoscenti Health Institute (2001; advisor), iSpecimen (2010; founder), ParetoBio Inc (2018, founder)

Teaching:
I teach the "Introduction to Anaerobe Physiology" course through Harvard's Microbial Sciences Inititative and the Mass. Host-Microbiome Center.
I also teach microbiome and pathogen genomics sections in the BCMP and HST course offerings at Harvard Medical School.
I am a mentor for Project Success at Harvard Medical School.

Clinical:
I am Associate Medical Director in the Clinical Microbiology and Molecular Pathology services at Brigham and Women's Hospital, my duties include oversight of complex molecular testing for infectious agents and surveillance programs for multi-drug resistant species and for spore forming pathogens.
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Research
research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
Most Recent  |  List All
  1. R01AI179807 (BRY, LYNN) Nov 24, 2023 - Oct 31, 2028
    NIH
    Harnessing commensal redox metabolism in infection prevention
    Role: Principal Investigator
  2. R03AI174158 (BRY, LYNN) Nov 14, 2022 - Oct 31, 2024
    NIH
    NMR-resolved dynamics of C. difficile metabolism
    Role: Principal Investigator
  3. R01AI153605 (BRY, LYNN) Feb 1, 2021 - Jan 31, 2026
    NIH
    Commensal control of C. difficile virulence
    Role: Principal Investigator
  4. MHMC (Lynn Bry) Jul 1, 2016 - Sep 30, 2026
    Multiple: Mass Life Sciences Center, NIH, FDA, biopharma
    Massachusetts Host-Microbiome Center
    Role Description: The Massachusetts Host-Microbiome Center's faculty and resources support >100 groups in the greater Boston area and beyond who are studying the role of the microbiota in health and disease, and for commercial applications.
    Role: Director
  5. R01HD061916 (MANTIS, NICHOLAS J) Sep 15, 2009 - Jul 31, 2016
    NIH
    Epithelial Glycoconjugates as Barriers against Enteric Infections
    Role: Principal Investigator
clinical trials
The clinical trials listed below are automatically derived from ClinicalTrials.gov and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
NCT Short Title Overall Status Start Completion

Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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© 2024 President and Fellows of Harvard College
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.