Pteroylpolyglutamic Acids
"Pteroylpolyglutamic Acids" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Derivatives of folic acid (pteroylglutamic acid). In gamma-glutamyl linkage they are found in many tissues. They are converted to folic acid by the action of pteroylpolyglutamate hydrolase or synthesized from folic acid by the action of folate polyglutamate synthetase. Synthetic pteroylpolyglutamic acids, which are in alpha-glutamyl linkage, are active in bacterial growth assays.
Concept/Terms
Folate Polyglutamates- Folate Polyglutamates
- Polyglutamates, Folate
- Pteroylpolyglutamates
- Polyglutamate Folates
- Folates, Polyglutamate
Below are MeSH descriptors whose meaning is more general than "Pteroylpolyglutamic Acids".
Below are MeSH descriptors whose meaning is more specific than "Pteroylpolyglutamic Acids".
This graph shows the total number of publications written about "Pteroylpolyglutamic Acids" by people in Harvard Catalyst Profiles by year, and whether "Pteroylpolyglutamic Acids" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 2 | 2 |
| 2012 | 1 | 0 | 1 |
Below are the most recent publications written about "Pteroylpolyglutamic Acids" by people in Profiles.
-
Maternal and child undernutrition and overweight in low-income and middle-income countries. Lancet. 2013 Aug 03; 382(9890):427-451.
-
Folates and S-adenosylmethionine for major depressive disorder. Can J Psychiatry. 2012 Jul; 57(7):406-13.
-
Functional loss of the reduced folate carrier enhances the antitumor activities of novel antifolates with selective uptake by the proton-coupled folate transporter. Mol Pharmacol. 2012 Oct; 82(4):591-600.
-
George Herman "Babe" Ruth Jr: baseball star and early participant in a cancer clinical trial. Mayo Clin Proc. 2008 Nov; 83(11):1262.
-
Nutrients involved in one-carbon metabolism and risk of breast cancer among premenopausal women. Cancer Epidemiol Biomarkers Prev. 2007 Dec; 16(12):2787-90.
-
2756GG genotype of methionine synthase reductase gene is more prevalent in rheumatoid arthritis patients treated with methotrexate and is associated with methotrexate-induced nodulosis. J Rheumatol. 2007 Aug; 34(8):1664-9.
-
Contribution of methylenetetrahydrofolate reductase (MTHFR) polymorphisms to negative symptoms in schizophrenia. Biol Psychiatry. 2008 Jan 01; 63(1):42-8.
-
Impaired spatial memory in APP-overexpressing mice on a homocysteinemia-inducing diet. Neurobiol Aging. 2007 Aug; 28(8):1195-205.
-
Prostate-specific membrane antigen: a novel folate hydrolase in human prostatic carcinoma cells. Clin Cancer Res. 1996 Sep; 2(9):1445-51.
-
Inhibition of phosphoribosylaminoimidazolecarboxamide transformylase by methotrexate and dihydrofolic acid polyglutamates. Proc Natl Acad Sci U S A. 1985 Aug; 82(15):4881-5.