TNF Receptor-Associated Factor 1

"TNF Receptor-Associated Factor 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A signal transducing tumor necrosis factor receptor associated factor that is involved in TNF RECEPTOR feedback regulation. It is similar in structure and appears to work in conjunction with TNF RECEPTOR-ASSOCIATED FACTOR 2 to inhibit APOPTOSIS.

Descriptor ID

D047990

MeSH Number(s)

D12.644.360.024.500.500

D12.776.157.057.500.500

D12.776.476.024.500.500

Concept/Terms

TNF Receptor-Associated Factor 1

Below are MeSH descriptors whose meaning is more general than "TNF Receptor-Associated Factor 1".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intracellular Signaling Peptides and Proteins [D12.644.360]
Adaptor Proteins, Signal Transducing [D12.644.360.024]
Tumor Necrosis Factor Receptor-Associated Peptides and Proteins [D12.644.360.024.500]
TNF Receptor-Associated Factor 1 [D12.644.360.024.500.500]
Proteins [D12.776]
Carrier Proteins [D12.776.157]
Adaptor Proteins, Signal Transducing [D12.776.157.057]
Tumor Necrosis Factor Receptor-Associated Peptides and Proteins [D12.776.157.057.500]
TNF Receptor-Associated Factor 1 [D12.776.157.057.500.500]
Intracellular Signaling Peptides and Proteins [D12.776.476]
Adaptor Proteins, Signal Transducing [D12.776.476.024]
Tumor Necrosis Factor Receptor-Associated Peptides and Proteins [D12.776.476.024.500]
TNF Receptor-Associated Factor 1 [D12.776.476.024.500.500]

Below are MeSH descriptors whose meaning is related to "TNF Receptor-Associated Factor 1".

Below are MeSH descriptors whose meaning is more specific than "TNF Receptor-Associated Factor 1".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "TNF Receptor-Associated Factor 1" by people in Harvard Catalyst Profiles by year, and whether "TNF Receptor-Associated Factor 1" was a major or minor topic of these publication.

Bar chart showing 30 publications over 14 distinct years, with a maximum of 6 publications in 2007

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	0	1	1
1996	0	2	2
1997	0	3	3
1999	0	3	3
2000	0	3	3
2001	0	2	2
2003	0	2	2
2005	2	0	2
2007	5	1	6
2008	1	0	1
2009	0	1	1
2010	1	0	1
2012	0	1	1
2015	2	0	2

Below are the most recent publications written about "TNF Receptor-Associated Factor 1" by people in Profiles.

TRAF1 Coordinates Polyubiquitin Signaling to Enhance Epstein-Barr Virus LMP1-Mediated Growth and Survival Pathway Activation. PLoS Pathog. 2015 May; 11(5):e1004890.

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TRAF1/C5 but not PTPRC variants are potential predictors of rheumatoid arthritis response to anti-tumor necrosis factor therapy. Biomed Res Int. 2015; 2015:490295.

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A genetic study on C5-TRAF1 and progression of joint damage in rheumatoid arthritis. Arthritis Res Ther. 2015 Jan 08; 17:1.

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Protein interactions of the transcription factor Hoxa1. BMC Dev Biol. 2012 Oct 22; 12:29.

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Patient samples of renal cell carcinoma show reduced expression of TRAF1 compared with normal kidney and functional studies in vitro indicate TRAF1 promotes apoptosis: potential for targeted therapy. Pathology. 2012 Aug; 44(5):453-9.

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Tumor necrosis factor receptor-associated factor 1 (TRAF1) deficiency attenuates atherosclerosis in mice by impairing monocyte recruitment to the vessel wall. Circulation. 2010 May 11; 121(18):2033-44.

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Adiponectin inhibits pro-inflammatory signaling in human macrophages independent of interleukin-10. J Biol Chem. 2009 Sep 18; 284(38):25569-75.

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Susceptibility variants for rheumatoid arthritis in the TRAF1-C5 and 6q23 loci: a meta-analysis. Ann Rheum Dis. 2010 Mar; 69(3):561-6.

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Expression of apoptotic tumour necrosis factor receptor-associated factor, caspase recruitment domain and cell death-inducing DFF-45 effector genes in therapy-treated renal cell carcinoma. Nephrology (Carlton). 2009 Apr; 14(2):205-12.

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Association of the TRAF1-C5 locus on chromosome 9 with juvenile idiopathic arthritis. Arthritis Rheum. 2008 Jul; 58(7):2206-7.

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