Group VI Phospholipases A2

"Group VI Phospholipases A2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A calcium-independent phospholipase A2 group that may play a role in membrane phospholipid remodeling and homeostasis by controling the levels of PHOSPHATIDYLCHOLINE in mammalian cell membranes.

Descriptor ID

D054522

MeSH Number(s)

D08.811.277.352.100.680.750.937.300.249

Concept/Terms

Group VI Phospholipases A2

Below are MeSH descriptors whose meaning is more general than "Group VI Phospholipases A2".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Hydrolases [D08.811.277]
Esterases [D08.811.277.352]
Carboxylic Ester Hydrolases [D08.811.277.352.100]
Phospholipases [D08.811.277.352.100.680]
Phospholipases A [D08.811.277.352.100.680.750]
Phospholipases A2 [D08.811.277.352.100.680.750.937]
Phospholipases A2, Calcium-Independent [D08.811.277.352.100.680.750.937.300]
Group VI Phospholipases A2 [D08.811.277.352.100.680.750.937.300.249]

Below are MeSH descriptors whose meaning is related to "Group VI Phospholipases A2".

Below are MeSH descriptors whose meaning is more specific than "Group VI Phospholipases A2".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Group VI Phospholipases A2" by people in Harvard Catalyst Profiles by year, and whether "Group VI Phospholipases A2" was a major or minor topic of these publication.

Below are the most recent publications written about "Group VI Phospholipases A2" by people in Profiles.

Genome sequencing reveals novel noncoding variants in PLA2G6 and LMNB1 causing progressive neurologic disease. Mol Genet Genomic Med. 2022 04; 10(4):e1892.

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Widening the MRI Findings of PLA2G6-Associated Neurodegeneration. Neuropediatrics. 2021 12; 52(6):509-510.

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Amorphous solid dispersion of Berberine mitigates apoptosis via iPLA2ß/Cardiolipin/Opa1 pathway in db/db mice and in Palmitate-treated MIN6 ß-cells. Int J Biol Sci. 2019; 15(7):1533-1545.

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Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways. Nat Commun. 2018 11 14; 9(1):4774.

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Case report of a novel homozygous splice site mutation in PLA2G6 gene causing infantile neuroaxonal dystrophy in a Sudanese family. BMC Med Genet. 2018 05 08; 19(1):72.

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Rare germline variants in known melanoma susceptibility genes in familial melanoma. Hum Mol Genet. 2017 12 15; 26(24):4886-4895.

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PLA2G6 mutations and Parkinsonism: Long-term follow-up of clinical features and neuropathology. Mov Disord. 2016 12; 31(12):1927-1929.

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Clinical heterogeneity of PLA2G6-related Parkinsonism: analysis of two Saudi families. BMC Res Notes. 2016 Jun 07; 9:295.

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Loss of PLA2G6 leads to elevated mitochondrial lipid peroxidation and mitochondrial dysfunction. Brain. 2015 Jul; 138(Pt 7):1801-16.

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A novel homozygous PLA2G6 mutation causes dystonia-parkinsonism. Parkinsonism Relat Disord. 2015 Mar; 21(3):337-9.

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