Carbohydrate Epimerases

"Carbohydrate Epimerases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Enzymes that catalyze the epimerization of chiral centers within carbohydrates or their derivatives. EC 5.1.3.

Descriptor ID

D002238

MeSH Number(s)

D08.811.399.894.500

Concept/Terms

Carbohydrate Epimerases

Below are MeSH descriptors whose meaning is more general than "Carbohydrate Epimerases".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Isomerases [D08.811.399]
Racemases and Epimerases [D08.811.399.894]
Carbohydrate Epimerases [D08.811.399.894.500]

Below are MeSH descriptors whose meaning is related to "Carbohydrate Epimerases".

Below are MeSH descriptors whose meaning is more specific than "Carbohydrate Epimerases".

Carbohydrate Epimerases
UDPglucose 4-Epimerase

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Carbohydrate Epimerases" by people in Harvard Catalyst Profiles by year, and whether "Carbohydrate Epimerases" was a major or minor topic of these publication.

Bar chart showing 13 publications over 8 distinct years, with a maximum of 3 publications in 1994 and 1999

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	3	0	3
1995	1	0	1
1998	0	1	1
1999	1	2	3
2003	2	0	2
2010	0	1	1
2013	1	0	1
2020	1	0	1

Below are the most recent publications written about "Carbohydrate Epimerases" by people in Profiles.

PelX is a UDP-N-acetylglucosamine C4-epimerase involved in Pel polysaccharide-dependent biofilm formation. J Biol Chem. 2020 08 21; 295(34):11949-11962.

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Erythritol feeds the pentose phosphate pathway via three new isomerases leading to D-erythrose-4-phosphate in Brucella. Proc Natl Acad Sci U S A. 2014 Dec 16; 111(50):17815-20.

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Common variants on Xq28 conferring risk of schizophrenia in Han Chinese. Schizophr Bull. 2014 Jul; 40(4):777-86.

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Heterozygous UDP-GlcNAc 2-epimerase and N-acetylmannosamine kinase domain mutations in the GNE gene result in a less severe GNE myopathy phenotype compared to homozygous N-acetylmannosamine kinase domain mutations. J Neurol Sci. 2012 Jul 15; 318(1-2):100-5.

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The crystal structure of ADP-L-glycero-D-manno-heptose-6-epimerase (HP0859) from Helicobacter pylori. Biochim Biophys Acta. 2011 Dec; 1814(12):1641-7.

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Identification, tissue distribution, and molecular modeling of novel human isoforms of the key enzyme in sialic acid synthesis, UDP-GlcNAc 2-epimerase/ManNAc kinase. Biochemistry. 2011 Oct 18; 50(41):8914-25.

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Disruption of heparan sulfate proteoglycan conformation perturbs B-cell maturation and APRIL-mediated plasma cell survival. Blood. 2011 Jun 09; 117(23):6162-71.

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Functional classification of protein 3D structures from predicted local interaction sites. J Bioinform Comput Biol. 2010 Dec; 8 Suppl 1:1-15.

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Crystal structure of the N-acetylmannosamine kinase domain of GNE. PLoS One. 2009 Oct 20; 4(10):e7165.

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The 1.6-A resolution crystal structure of NovW: a 4-keto-6-deoxy sugar epimerase from the novobiocin biosynthetic gene cluster of Streptomyces spheroides. Proteins. 2006 Apr 01; 63(1):261-5.

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