Cholinesterase Reactivators

"Cholinesterase Reactivators" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Drugs used to reverse the inactivation of cholinesterase caused by organophosphates or sulfonates. They are an important component of therapy in agricultural, industrial, and military poisonings by organophosphates and sulfonates.

Descriptor ID

D002801

MeSH Number(s)

D27.505.519.405.347

D27.505.519.625.120.400

D27.505.696.577.120.400

Concept/Terms

Cholinesterase Reactivators

Organophosphate Insecticide Antagonists

Insecticides, Organothiophosphate, Antagonists

Below are MeSH descriptors whose meaning is more general than "Cholinesterase Reactivators".

Chemicals and Drugs [D]
Chemical Actions and Uses [D27]
Pharmacologic Actions [D27.505]
Molecular Mechanisms of Pharmacological Action [D27.505.519]
Enzyme Reactivators [D27.505.519.405]
Cholinesterase Reactivators [D27.505.519.405.347]
Neurotransmitter Agents [D27.505.519.625]
Cholinergic Agents [D27.505.519.625.120]
Cholinesterase Reactivators [D27.505.519.625.120.400]
Physiological Effects of Drugs [D27.505.696]
Neurotransmitter Agents [D27.505.696.577]
Cholinergic Agents [D27.505.696.577.120]
Cholinesterase Reactivators [D27.505.696.577.120.400]

Below are MeSH descriptors whose meaning is related to "Cholinesterase Reactivators".

Below are MeSH descriptors whose meaning is more specific than "Cholinesterase Reactivators".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Cholinesterase Reactivators" by people in Harvard Catalyst Profiles by year, and whether "Cholinesterase Reactivators" was a major or minor topic of these publication.

Bar chart showing 5 publications over 3 distinct years, with a maximum of 3 publications in 1995

To see the data from this visualization as text, click here.

Year	Minor Topic	Total
1995	3	3
2012	1	1
2015	1	1

Below are the most recent publications written about "Cholinesterase Reactivators" by people in Profiles.

The First Use of Pralidoxime in a Child With Rivastigmine Poisoning. Pediatr Emerg Care. 2018 Oct; 34(10):e184-e186.

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Early brain magnetic resonance imaging can predict short and long-term outcomes after organophosphate poisoning in a rat model. Neurotoxicology. 2015 May; 48:206-16.

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An in vivo zebrafish screen identifies organophosphate antidotes with diverse mechanisms of action. J Biomol Screen. 2013 Jan; 18(1):108-15.

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Pralidoxime rescues both muscarinic and nicotinic systems. Anesth Analg. 2005 Sep; 101(3):926-927.

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Nerve agent toxicology. JEMS. 2003 Dec; 28(12):16; author reply 16.

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Myosin is involved in postmitotic cell spreading. J Cell Biol. 1995 Oct; 131(1):179-89.

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Organophosphorous compound poisoning : prolonged therapy in absence of intermediate neurotoxic syndrome. J Assoc Physicians India. 1995 Jan; 43(1):59-60.

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Use of C1300 neuroblastoma cells to evaluate the protective value of hexamethonium, trimethaphan, hemicholinium, and triethylcholine against diisopropyl phosphorofluoridate toxicity. J Pharm Sci. 1995 Jan; 84(1):65-70.

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Edrophonium and pralidoxime. Anesth Analg. 1989 Jun; 68(6):826-7.

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Combined atropine and 2-PAM Cl effects on tracking performance and visual, physiological, and psychological functions. Aviat Space Environ Med. 1988 Dec; 59(12):1125-32.

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Anesth Analg
Pediatr Emerg Care
Aviat Space Environ Med
Neurotoxicology
JEMS
J Pharm Sci
J Cell Biol
J Biomol Screen
J Assoc Physicians India