Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Perforin

"Perforin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

A calcium-dependent pore-forming protein synthesized in cytolytic LYMPHOCYTES and sequestered in secretory granules. Upon immunological reaction between a cytolytic lymphocyte and a target cell, perforin is released at the plasma membrane and polymerizes into transmembrane tubules (forming pores) which lead to death of a target cell.


This graph shows the total number of publications written about "Perforin" by people in Harvard Catalyst Profiles by year, and whether "Perforin" was a major or minor topic of these publication.
Bar chart showing 110 publications over 26 distinct years, with a maximum of 9 publications in 2003 and 2018
To see the data from this visualization as text, click here.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.