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Gerassimos M. Makrigiorgos, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Herter-Sprie GS, Korideck H, Christensen CL, Herter JM, Rhee K, Berbeco RI, Bennett DG, Akbay EA, Kozono D, Mak RH, Makrigiorgos GM, Kimmelman AC, Wong KK. Author Correction: Image-guided radiotherapy platform using single nodule conditional lung cancer mouse models. Nat Commun. 2020 Apr 09; 11(1):1835. PMID: 32273495.
    Citations:    
  2. Parsons HA, Rhoades J, Reed SC, Gydush G, Ram P, Exman P, Xiong K, Lo CC, Li T, Fleharty M, Kirkner GJ, Rotem D, Cohen O, Yu F, Fitarelli-Kiehl M, Leong KW, Hughes ME, Rosenberg SM, Collins LC, Miller KD, Blumenstiel B, Trippa L, Cibulskis C, Neuberg DS, DeFelice M, Freeman SS, Lennon NJ, Wagle N, Ha G, Stover DG, Choudhury AD, Getz G, Winer EP, Meyerson M, Lin NU, Krop I, Love JC, Makrigiorgos GM, Partridge AH, Mayer EL, Golub TR, Adalsteinsson VA. Sensitive Detection of Minimal Residual Disease in Patients Treated for Early-Stage Breast Cancer. Clin Cancer Res. 2020 Jun 01; 26(11):2556-2564. PMID: 32170028.
    Citations:    
  3. Leong KW, Yu F, Adalsteinsson VA, Reed S, Gydush G, Ladas I, Li J, Tantisira KG, Makrigiorgos GM. A nuclease-polymerase chain reaction enables amplification of probes used for capture-based DNA target enrichment. Nucleic Acids Res. 2019 12 16; 47(22):e147. PMID: 31598677.
    Citations:    
  4. Markou A, Tzanikou E, Ladas I, Makrigiorgos GM, Lianidou E. Nuclease-Assisted Minor Allele Enrichment Using Overlapping Probes-Assisted Amplification-Refractory Mutation System: An Approach for the Improvement of Amplification-Refractory Mutation System-Polymerase Chain Reaction Specificity in Liquid Biopsies. Anal Chem. 2019 10 15; 91(20):13105-13111. PMID: 31538770.
    Citations:    
  5. Makrigiorgos GM. Extreme PCR Meets High-Speed Melting: A Step Closer to Molecular Diagnostics "While You Wait". Clin Chem. 2019 02; 65(2):217-219. PMID: 30530717.
    Citations:    
  6. Fitarelli-Kiehl M, Yu F, Ashtaputre R, Leong KW, Ladas I, Supplee J, Paweletz C, Mitra D, Schoenfeld JD, Parangi S, Makrigiorgos GM. Denaturation-Enhanced Droplet Digital PCR for Liquid Biopsies. Clin Chem. 2018 12; 64(12):1762-1771. PMID: 30274976.
    Citations:    Fields:    
  7. Ladas I, Yu F, Leong KW, Fitarelli-Kiehl M, Song C, Ashtaputre R, Kulke M, Mamon H, Makrigiorgos GM. Enhanced detection of microsatellite instability using pre-PCR elimination of wild-type DNA homo-polymers in tissue and liquid biopsies. Nucleic Acids Res. 2018 07 06; 46(12):e74. PMID: 29635638.
    Citations:    Fields:    
  8. Guthier CV, D'Amico AV, King MT, Nguyen PL, Orio PF, Sridhar S, Makrigiorgos GM, Cormack RA. Determining optimal eluter design by modeling physical dose enhancement in brachytherapy. Med Phys. 2018 Jun 15. PMID: 29905964.
    Citations:    Fields:    
  9. Ladas I, Fitarelli-Kiehl M, Song C, Adalsteinsson VA, Parsons HA, Lin NU, Wagle N, Makrigiorgos GM. Multiplexed Elimination of Wild-Type DNA and High-Resolution Melting Prior to Targeted Resequencing of Liquid Biopsies. Clin Chem. 2017 Oct; 63(10):1605-1613. PMID: 28679646.
    Citations:    Fields:    Translation:HumansCells
  10. Liu Y, Song C, Ladas I, Fitarelli-Kiehl M, Makrigiorgos GM. Methylation-sensitive enrichment of minor DNA alleles using a double-strand DNA-specific nuclease. Nucleic Acids Res. 2017 04 07; 45(6):e39. PMID: 27903892.
    Citations: 3     Fields:    Translation:HumansCells
  11. Song C, Liu Y, Fontana R, Makrigiorgos A, Mamon H, Kulke MH, Makrigiorgos GM. Elimination of unaltered DNA in mixed clinical samples via nuclease-assisted minor-allele enrichment. Nucleic Acids Res. 2016 Nov 02; 44(19):e146. PMID: 27431322.
    Citations: 9     Fields:    Translation:Humans
  12. Detappe A, Kunjachan S, Sancey L, Motto-Ros V, Biancur D, Drane P, Guieze R, Makrigiorgos GM, Tillement O, Langer R, Berbeco R. Advanced multimodal nanoparticles delay tumor progression with clinical radiation therapy. J Control Release. 2016 09 28; 238:103-113. PMID: 27423325.
    Citations: 6     Fields:    Translation:Animals
  13. Duquette M, Sadow PM, Husain A, Sims JN, Antonello ZA, Fischer AH, Song C, Castellanos-Rizaldos E, Makrigiorgos GM, Kurebayashi J, Nose V, Van Hummelen P, Bronson RT, Vinco M, Giordano TJ, Dias-Santagata D, Pandolfi PP, Nucera C. Metastasis-associated MCL1 and P16 copy number alterations dictate resistance to vemurafenib in a BRAFV600E patient-derived papillary thyroid carcinoma preclinical model. Oncotarget. 2015 Dec 15; 6(40):42445-67. PMID: 26636651.
    Citations: 7     Fields:    Translation:HumansAnimals
  14. Brivio D, Zygmanski P, Arnoldussen M, Hanlon J, Chell E, Sajo E, Makrigiorgos GM, Ngwa W. Kilovoltage radiosurgery with gold nanoparticles for neovascular age-related macular degeneration (AMD): a Monte Carlo evaluation. Phys Med Biol. 2015 Dec 21; 60(24):9203-13. PMID: 26576672.
    Citations: 1     Fields:    Translation:Humans
  15. Ngwa W, Ngoma T, Zietman A, Mayr N, Elzawawy A, Winningham TA, Balogun O, Enwerem-Bromson N, Ntizimira C, Olopade OI, Oluwole D, Odedina F, Williams M, Flanigan J, Asana L, Ngwa K, Avery S, Pollard JM, Roland T, Funwi-gabga N, Mbarika V, Hardenbergh P, Winkfield K, Pipman Y, Stefan C, Ngoma M, Mohammed S, Katz M, Erno S, Moni J, Fitzgerald T, Tonlaar N, Efstathiou J, Gierga D, Ayo C, Knaul F, Gospodarowicz M, Makrigiorgos GM, Nguyen PL. Closing the Cancer Divide Through Ubuntu: Information and Communication Technology-Powered Models for Global Radiation Oncology. Int J Radiat Oncol Biol Phys. 2016 Mar 01; 94(3):440-9. PMID: 26867873.
    Citations: 4     Fields:    Translation:Humans
  16. Kunjachan S, Detappe A, Kumar R, Ireland T, Cameron L, Biancur DE, Motto-Ros V, Sancey L, Sridhar S, Makrigiorgos GM, Berbeco RI. Nanoparticle Mediated Tumor Vascular Disruption: A Novel Strategy in Radiation Therapy. Nano Lett. 2015 Nov 11; 15(11):7488-96. PMID: 26418302.
    Citations: 16     Fields:    Translation:HumansCells
  17. Song C, Castellanos-Rizaldos E, Bejar R, Ebert BL, Makrigiorgos GM. DMSO Increases Mutation Scanning Detection Sensitivity of High-Resolution Melting in Clinical Samples. Clin Chem. 2015 Nov; 61(11):1354-62. PMID: 26432802.
    Citations: 2     Fields:    Translation:HumansCells
  18. Castellanos-Rizaldos E, Paweletz C, Song C, Oxnard GR, Mamon H, Jänne PA, Makrigiorgos GM. Enhanced ratio of signals enables digital mutation scanning for rare allele detection. J Mol Diagn. 2015 May; 17(3):284-92. PMID: 25772705.
    Citations: 4     Fields:    Translation:HumansCells
  19. Burnham L, Matlak S, Makrigiorgos G, Braun N, Knapp BP, Merewood A. Breastfeeding and coffee consumption in children younger than 2 years in Boston, Massachusetts, USA. J Hum Lact. 2015 May; 31(2):267-72. PMID: 25678326.
    Citations:    Fields:    Translation:Humans
  20. Sinha N, Cifter G, Sajo E, Kumar R, Sridhar S, Nguyen PL, Cormack RA, Makrigiorgos GM, Ngwa W. Brachytherapy application with in situ dose painting administered by gold nanoparticle eluters. Int J Radiat Oncol Biol Phys. 2015 Feb 01; 91(2):385-92. PMID: 25482302.
    Citations: 11     Fields:    Translation:Humans
  21. Murphy DM, Castellanos-Rizaldos E, Makrigiorgos GM. Enriching mutant sequences by modulating the denaturation time during PCR. Clin Chem. 2014 Jul; 60(7):1014-6. PMID: 24799525.
    Citations:    Fields:    Translation:HumansCells
  22. Ngwa W, Kumar R, Sridhar S, Korideck H, Zygmanski P, Cormack RA, Berbeco R, Makrigiorgos GM. Targeted radiotherapy with gold nanoparticles: current status and future perspectives. Nanomedicine (Lond). 2014 May; 9(7):1063-82. PMID: 24978464.
    Citations: 27     Fields:    Translation:Humans
  23. Castellanos-Rizaldos E, Milbury CA, Karatza E, Chen CC, Makrigiorgos GM, Merewood A. COLD-PCR amplification of bisulfite-converted DNA allows the enrichment and sequencing of rare un-methylated genomic regions. PLoS One. 2014; 9(4):e94103. PMID: 24728321.
    Citations: 4     Fields:    Translation:Cells
  24. Castellanos-Rizaldos E, Milbury CA, Guha M, Makrigiorgos GM. COLD-PCR enriches low-level variant DNA sequences and increases the sensitivity of genetic testing. Methods Mol Biol. 2014; 1102:623-39. PMID: 24259002.
    Citations: 1     Fields:    Translation:HumansCells
  25. Kumar R, Korideck H, Ngwa W, Berbeco RI, Makrigiorgos GM, Sridhar S. Third generation gold nanoplatform optimized for radiation therapy. Transl Cancer Res. 2013 Aug; 2(4). PMID: 24392307.
    Citations: 14     
  26. Guha M, Castellanos-Rizaldos E, Makrigiorgos GM. DISSECT Method Using PNA-LNA Clamp Improves Detection of EGFR T790m Mutation. PLoS One. 2013; 8(6):e67782. PMID: 23805327.
    Citations: 8     Fields:    Translation:HumansCells
  27. Guha M, Castellanos-Rizaldos E, Liu P, Mamon H, Makrigiorgos GM. Differential strand separation at critical temperature: a minimally disruptive enrichment method for low-abundance unknown DNA mutations. Nucleic Acids Res. 2013 Feb 01; 41(3):e50. PMID: 23258702.
    Citations: 9     Fields:    Translation:HumansCells
  28. Castellanos-Rizaldos E, Milbury CA, Makrigiorgos GM. Enrichment of mutations in multiple DNA sequences using COLD-PCR in emulsion. PLoS One. 2012; 7(12):e51362. PMID: 23236486.
    Citations: 3     Fields:    Translation:HumansCells
  29. Berbeco RI, Korideck H, Ngwa W, Kumar R, Patel J, Sridhar S, Johnson S, Price BD, Kimmelman A, Makrigiorgos GM. DNA damage enhancement from gold nanoparticles for clinical MV photon beams. Radiat Res. 2012 Dec; 178(6):604-8. PMID: 23148509.
    Citations: 18     Fields:    Translation:HumansCells
  30. Ngwa W, Korideck H, Kassis AI, Kumar R, Sridhar S, Makrigiorgos GM, Cormack RA. In vitro radiosensitization by gold nanoparticles during continuous low-dose-rate gamma irradiation with I-125 brachytherapy seeds. Nanomedicine. 2013 Jan; 9(1):25-7. PMID: 23041410.
    Citations: 22     Fields:    Translation:HumansCells
  31. Ngwa W, Makrigiorgos GM, Berbeco RI. Gold nanoparticle enhancement of stereotactic radiosurgery for neovascular age-related macular degeneration. Phys Med Biol. 2012 Oct 21; 57(20):6371-80. PMID: 22995994.
    Citations: 6     Fields:    Translation:Humans
  32. Castellanos-Rizaldos E, Liu P, Milbury CA, Guha M, Brisci A, Cremonesi L, Ferrari M, Mamon H, Makrigiorgos GM. Temperature-tolerant COLD-PCR reduces temperature stringency and enables robust mutation enrichment. Clin Chem. 2012 Jul; 58(7):1130-8. PMID: 22587896.
    Citations: 7     Fields:    Translation:HumansCells
  33. Sadacharan R, Santana S, Sanchez E, Matlak S, Grossman X, Makrigiorgos G, Merewood A. Are you Baby-Friendly? Knowledge deficit among US maternity staff. J Hum Lact. 2012 Aug; 28(3):359-62. PMID: 22584875.
    Citations:    Fields:    Translation:Humans
  34. Ngwa W, Tsiamas P, Zygmanski P, Makrigiorgos GM, Berbeco RI. A multipurpose quality assurance phantom for the small animal radiation research platform (SARRP). Phys Med Biol. 2012 May 07; 57(9):2575-86. PMID: 22491061.
    Citations: 4     Fields:    Translation:Animals
  35. Ngwa W, Makrigiorgos GM, Berbeco RI. Gold nanoparticle-aided brachytherapy with vascular dose painting: estimation of dose enhancement to the tumor endothelial cell nucleus. Med Phys. 2012 Jan; 39(1):392-8. PMID: 22225308.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  36. Milbury CA, Correll M, Quackenbush J, Rubio R, Makrigiorgos GM. COLD-PCR enrichment of rare cancer mutations prior to targeted amplicon resequencing. Clin Chem. 2012 Mar; 58(3):580-9. PMID: 22194627.
    Citations: 19     Fields:    Translation:HumansCells
  37. Ngwa W, Korideck H, Chin LM, Makrigiorgos GM, Berbeco RI. MOSFET assessment of radiation dose delivered to mice using the Small Animal Radiation Research Platform (SARRP). Radiat Res. 2011 Dec; 176(6):816-20. PMID: 21962005.
    Citations: 3     Fields:    Translation:Animals
  38. Song C, Milbury CA, Li J, Liu P, Zhao M, Makrigiorgos GM. Rapid and sensitive detection of KRAS mutation after fast-COLD-PCR enrichment and high-resolution melting analysis. Diagn Mol Pathol. 2011 Jun; 20(2):81-9. PMID: 21532494.
    Citations: 8     Fields:    Translation:Humans
  39. Makrigiorgos G, Santana S, Sanchez E, Sadacharan R, Stuebe A, Merewood A. A national website to track hospital discontinuation of formula sample pack distribution: accuracy of self-report. J Hum Lact. 2011 May; 27(2):113-4. PMID: 21527795.
    Citations: 1     Fields:    Translation:Humans
  40. Milbury CA, Chen CC, Mamon H, Liu P, Santagata S, Makrigiorgos GM. Multiplex amplification coupled with COLD-PCR and high resolution melting enables identification of low-abundance mutations in cancer samples with low DNA content. J Mol Diagn. 2011 Mar; 13(2):220-32. PMID: 21354058.
    Citations: 10     Fields:    Translation:HumansCells
  41. Milbury CA, Li J, Liu P, Makrigiorgos GM. COLD-PCR: improving the sensitivity of molecular diagnostics assays. Expert Rev Mol Diagn. 2011 Mar; 11(2):159-69. PMID: 21405967.
    Citations: 9     Fields:    Translation:HumansCells
  42. Li J, Jänne PA, Makrigiorgos GM. Biotinylated probe isolation of targeted gene region improves detection of T790M epidermal growth factor receptor mutation via peptide nucleic acid-enriched real-time PCR. Clin Chem. 2011 May; 57(5):770-3. PMID: 21325655.
    Citations: 3     Fields:    Translation:HumansCells
  43. Berbeco RI, Ngwa W, Makrigiorgos GM. Localized dose enhancement to tumor blood vessel endothelial cells via megavoltage X-rays and targeted gold nanoparticles: new potential for external beam radiotherapy. Int J Radiat Oncol Biol Phys. 2011 Sep 01; 81(1):270-6. PMID: 21163591.
    Citations: 32     Fields:    Translation:Cells
  44. Galbiati S, Brisci A, Lalatta F, Seia M, Makrigiorgos GM, Ferrari M, Cremonesi L. Full COLD-PCR protocol for noninvasive prenatal diagnosis of genetic diseases. Clin Chem. 2011 Jan; 57(1):136-8. PMID: 20974797.
    Citations: 12     Fields:    Translation:Humans
  45. Ngwa W, Makrigiorgos GM, Berbeco RI. Applying gold nanoparticles as tumor-vascular disrupting agents during brachytherapy: estimation of endothelial dose enhancement. Phys Med Biol. 2010 Nov 07; 55(21):6533-48. PMID: 20959684.
    Citations: 20     Fields:    Translation:HumansAnimals
  46. Milbury CA, Li J, Makrigiorgos GM. Ice-COLD-PCR enables rapid amplification and robust enrichment for low-abundance unknown DNA mutations. Nucleic Acids Res. 2011 Jan; 39(1):e2. PMID: 20937629.
    Citations: 25     Fields:    Translation:HumansCells
  47. Nagesha DK, Tada DB, Stambaugh CK, Gultepe E, Jost E, Levy CO, Cormack R, Makrigiorgos GM, Sridhar S. Radiosensitizer-eluting nanocoatings on gold fiducials for biological in-situ image-guided radio therapy (BIS-IGRT). Phys Med Biol. 2010 Oct 21; 55(20):6039-52. PMID: 20858923.
    Citations: 9     Fields:    Translation:Humans
  48. Zerilli F, Bonanno C, Shehi E, Amicarelli G, Adlerstein D, Makrigiorgos GM. Methylation-specific loop-mediated isothermal amplification for detecting hypermethylated DNA in simplex and multiplex formats. Clin Chem. 2010 Aug; 56(8):1287-96. PMID: 20551384.
    Citations: 6     Fields:    Translation:HumansCells
  49. Tada DB, Singh S, Nagesha D, Jost E, Levy CO, Gultepe E, Cormack R, Makrigiorgos GM, Sridhar S. Chitosan film containing poly(D,L-lactic-co-glycolic acid) nanoparticles: a platform for localized dual-drug release. Pharm Res. 2010 Aug; 27(8):1738-45. PMID: 20521086.
    Citations: 6     Fields:    
  50. Zhu X, Palmer MR, Makrigiorgos GM, Kassis AI. Solid-tumor radionuclide therapy dosimetry: new paradigms in view of tumor microenvironment and angiogenesis. Med Phys. 2010 Jun; 37(6):2974-84. PMID: 20632610.
    Citations: 7     Fields:    Translation:HumansAnimals
  51. Li J, Makrigiorgos GM. s-RT-MELT: a novel technology for mutation screening. Methods Mol Biol. 2010; 653:207-19. PMID: 20721745.
    Citations:    Fields:    Translation:HumansCells
  52. Li J, Milbury CA, Li C, Makrigiorgos GM. Two-round coamplification at lower denaturation temperature-PCR (COLD-PCR)-based sanger sequencing identifies a novel spectrum of low-level mutations in lung adenocarcinoma. Hum Mutat. 2009 Nov; 30(11):1583-90. PMID: 19760750.
    Citations: 23     Fields:    Translation:HumansCells
  53. Cormack RA, Sridhar S, Suh WW, D'Amico AV, Makrigiorgos GM. Biological in situ dose painting for image-guided radiation therapy using drug-loaded implantable devices. Int J Radiat Oncol Biol Phys. 2010 Feb 01; 76(2):615-23. PMID: 19879699.
    Citations: 9     Fields:    Translation:Humans
  54. Milbury CA, Li J, Makrigiorgos GM. COLD-PCR-enhanced high-resolution melting enables rapid and selective identification of low-level unknown mutations. Clin Chem. 2009 Dec; 55(12):2130-43. PMID: 19815609.
    Citations: 28     Fields:    Translation:HumansCells
  55. Lang JE, Magbanua MJ, Scott JH, Makrigiorgos GM, Wang G, Federman S, Esserman LJ, Park JW, Haqq CM. A comparison of RNA amplification techniques at sub-nanogram input concentration. BMC Genomics. 2009 Jul 20; 10:326. PMID: 19619282.
    Citations: 11     Fields:    Translation:HumansCells
  56. Li J, Makrigiorgos GM. COLD-PCR: a new platform for highly improved mutation detection in cancer and genetic testing. Biochem Soc Trans. 2009 Apr; 37(Pt 2):427-32. PMID: 19290875.
    Citations: 21     Fields:    Translation:Humans
  57. Li J, Wang L, Jänne PA, Makrigiorgos GM. Coamplification at lower denaturation temperature-PCR increases mutation-detection selectivity of TaqMan-based real-time PCR. Clin Chem. 2009 Apr; 55(4):748-56. PMID: 19233916.
    Citations: 21     Fields:    Translation:HumansCells
  58. Milbury CA, Li J, Makrigiorgos GM. PCR-based methods for the enrichment of minority alleles and mutations. Clin Chem. 2009 Apr; 55(4):632-40. PMID: 19201784.
    Citations: 41     Fields:    Translation:HumansCells
  59. Chin DW, Treister N, Friedland B, Cormack RA, Tishler RB, Makrigiorgos GM, Court LE. Effect of dental restorations and prostheses on radiotherapy dose distribution: a Monte Carlo study. J Appl Clin Med Phys. 2009 Feb 03; 10(1):2853. PMID: 19223833.
    Citations: 9     Fields:    Translation:Humans
  60. Mamon H, Hader C, Li J, Wang L, Kulke M, Amicarelli G, Shehi E, Adlerstein D, Roper K, Killion L, Hooshmand S, Makrigiorgos GM. Preferential amplification of apoptotic DNA from plasma: potential for enhancing detection of minor DNA alterations in circulating DNA. Clin Chem. 2008 Sep; 54(9):1582-4. PMID: 18755913.
    Citations: 6     Fields:    Translation:Humans
  61. Li J, Wang L, Mamon H, Kulke MH, Berbeco R, Makrigiorgos GM. Replacing PCR with COLD-PCR enriches variant DNA sequences and redefines the sensitivity of genetic testing. Nat Med. 2008 May; 14(5):579-84. PMID: 18408729.
    Citations: 89     Fields:    Translation:HumansCells
  62. Park MA, Mahmood A, Zimmerman RE, Limpa-Amara N, Makrigiorgos GM, Moore SC. Adsorption of metallic radionuclides on plastic phantom walls. Med Phys. 2008 Apr; 35(4):1606-10. PMID: 18491554.
    Citations: 5     Fields:    Translation:CellsPHPublic Health
  63. Bonanno C, Shehi E, Adlerstein D, Makrigiorgos GM. MS-FLAG, a novel real-time signal generation method for methylation-specific PCR. Clin Chem. 2007 Dec; 53(12):2119-27. PMID: 17962364.
    Citations: 9     Fields:    Translation:HumansCells
  64. Amicarelli G, Shehi E, Makrigiorgos GM, Adlerstein D. FLAG assay as a novel method for real-time signal generation during PCR: application to detection and genotyping of KRAS codon 12 mutations. Nucleic Acids Res. 2007; 35(19):e131. PMID: 17932053.
    Citations: 18     Fields:    Translation:HumansCells
  65. Wang F, Wang L, Briggs C, Sicinska E, Gaston SM, Mamon H, Kulke MH, Zamponi R, Loda M, Maher E, Ogino S, Fuchs CS, Li J, Hader C, Makrigiorgos GM. DNA degradation test predicts success in whole-genome amplification from diverse clinical samples. J Mol Diagn. 2007 Sep; 9(4):441-51. PMID: 17690213.
    Citations: 17     Fields:    Translation:HumansCells
  66. Li J, Berbeco R, Distel RJ, Jänne PA, Wang L, Makrigiorgos GM. s-RT-MELT for rapid mutation scanning using enzymatic selection and real time DNA-melting: new potential for multiplex genetic analysis. Nucleic Acids Res. 2007; 35(12):e84. PMID: 17545195.
    Citations: 8     Fields:    Translation:HumansCells
  67. Xiang HF, Song JS, Chin DW, Cormack RA, Tishler RB, Makrigiorgos GM, Court LE, Chin LM. Build-up and surface dose measurements on phantoms using micro-MOSFET in 6 and 10 MV x-ray beams and comparisons with Monte Carlo calculations. Med Phys. 2007 Apr; 34(4):1266-73. PMID: 17500458.
    Citations: 7     Fields:    Translation:Humans
  68. Li J, Makrigiorgos GM. Anti-primer quenching-based real-time PCR for simplex or multiplex DNA quantification and single-nucleotide polymorphism genotyping. Nat Protoc. 2007; 2(1):50-8. PMID: 17401338.
    Citations: 7     Fields:    
  69. Amicarelli G, Adlerstein D, Shehi E, Wang F, Makrigiorgos GM. Genotype-specific signal generation based on digestion of 3-way DNA junctions: application to KRAS variation detection. Clin Chem. 2006 Oct; 52(10):1855-63. PMID: 16916990.
    Citations: 5     Fields:    Translation:Humans
  70. Ogino S, Kawasaki T, Brahmandam M, Cantor M, Kirkner GJ, Spiegelman D, Makrigiorgos GM, Weisenberger DJ, Laird PW, Loda M, Fuchs CS. Precision and performance characteristics of bisulfite conversion and real-time PCR (MethyLight) for quantitative DNA methylation analysis. J Mol Diagn. 2006 May; 8(2):209-17. PMID: 16645207.
    Citations: 176     Fields:    Translation:HumansCells
  71. Roy K, Wang L, Makrigiorgos GM, Price BD. Methylation of the ATM promoter in glioma cells alters ionizing radiation sensitivity. Biochem Biophys Res Commun. 2006 Jun 09; 344(3):821-6. PMID: 16631604.
    Citations: 22     Fields:    Translation:HumansCells
  72. Li J, Wang F, Mamon H, Kulke MH, Harris L, Maher E, Wang L, Makrigiorgos GM. Antiprimer quenching-based real-time PCR and its application to the analysis of clinical cancer samples. Clin Chem. 2006 Apr; 52(4):624-33. PMID: 16469859.
    Citations: 12     Fields:    Translation:Humans
  73. Wang F, Kaur M, Liu WH, Zhu P, Li J, Wang L, Makrigiorgos GM. High-throughput scanning of breast tumor surgical specimens for low-level mutations. Clin Chem Lab Med. 2005; 43(8):810-6. PMID: 16201889.
    Citations:    Fields:    Translation:HumansCells
  74. Wang G, Maher E, Brennan C, Chin L, Leo C, Kaur M, Zhu P, Rook M, Wolfe JL, Makrigiorgos GM. DNA amplification method tolerant to sample degradation. Genome Res. 2004 Nov; 14(11):2357-66. PMID: 15520297.
    Citations: 21     Fields:    Translation:HumansCells
  75. Wang G, Brennan C, Rook M, Wolfe JL, Leo C, Chin L, Pan H, Liu WH, Price B, Makrigiorgos GM. Balanced-PCR amplification allows unbiased identification of genomic copy changes in minute cell and tissue samples. Nucleic Acids Res. 2004 May 21; 32(9):e76. PMID: 15155823.
    Citations: 20     Fields:    Translation:HumansCells
  76. Chen S, Wang G, Makrigiorgos GM, Price BD. Stable siRNA-mediated silencing of ATM alters the transcriptional profile of HeLa cells. Biochem Biophys Res Commun. 2004 May 14; 317(4):1037-44. PMID: 15094373.
    Citations: 9     Fields:    Translation:HumansCells
  77. Liu WH, Kaur M, Wang G, Zhu P, Zhang Y, Makrigiorgos GM. Inverse PCR-based RFLP scanning identifies low-level mutation signatures in colon cells and tumors. Cancer Res. 2004 Apr 01; 64(7):2544-51. PMID: 15059910.
    Citations: 2     Fields:    Translation:HumansCells
  78. Liu WH, Makrigiorgos GM. Sensitive and quantitative detection of mutations associated with clinical resistance to STI-571. Leuk Res. 2003 Nov; 27(11):979-82. PMID: 12859990.
    Citations: 3     Fields:    Translation:Humans
  79. Liu WH, Kaur M, Makrigiorgos GM. Detection of hotspot mutations and polymorphisms using an enhanced PCR-RFLP approach. Hum Mutat. 2003 May; 21(5):535-41. PMID: 12673796.
    Citations: 2     Fields:    Translation:Humans
  80. Kaur M, Makrigiorgos GM. Novel amplification of DNA in a hairpin structure: towards a radical elimination of PCR errors from amplified DNA. Nucleic Acids Res. 2003 Mar 15; 31(6):e26. PMID: 12626725.
    Citations: 4     Fields:    Translation:HumansCells
  81. Xue LY, Butler NJ, Makrigiorgos GM, Adelstein SJ, Kassis AI. Bystander effect produced by radiolabeled tumor cells in vivo. Proc Natl Acad Sci U S A. 2002 Oct 15; 99(21):13765-70. PMID: 12368480.
    Citations: 31     Fields:    Translation:HumansAnimalsCells
  82. Kaur M, Zhang Y, Liu WH, Tetradis S, Price BD, Makrigiorgos GM. Ligation of a primer at a mutation: a method to detect low level mutations in DNA. Mutagenesis. 2002 Sep; 17(5):365-74. PMID: 12202623.
    Citations: 4     Fields:    Translation:HumansCells
  83. Makrigiorgos GM, Chakrabarti S, Zhang Y, Kaur M, Price BD. A PCR-based amplification method retaining the quantitative difference between two complex genomes. Nat Biotechnol. 2002 Sep; 20(9):936-9. PMID: 12161758.
    Citations: 16     Fields:    Translation:Humans
  84. Zhang Y, Kaur M, Price BD, Tetradis S, Makrigiorgos GM. An amplification and ligation-based method to scan for unknown mutations in DNA. Hum Mutat. 2002 Aug; 20(2):139-47. PMID: 12124995.
    Citations: 5     Fields:    Translation:HumansCells
  85. Maulik G, Salgia R, Makrigiorgos GM. Flow cytometric determination of lipid peroxidation using fluoresceinated phosphoethanolamine. Methods Enzymol. 2002; 352:80-91. PMID: 12125379.
    Citations: 1     Fields:    Translation:AnimalsCells
  86. Zhang Y, Price BD, Tetradis S, Chakrabarti S, Maulik G, Makrigiorgos GM. Reproducible and inexpensive probe preparation for oligonucleotide arrays. Nucleic Acids Res. 2001 Jul 01; 29(13):E66-6. PMID: 11433042.
    Citations: 4     Fields:    Translation:HumansCells
  87. Chakrabarti S, Price BD, Tetradis S, Fox EA, Zhang Y, Maulik G, Makrigiorgos GM. Highly selective isolation of unknown mutations in diverse DNA fragments: toward new multiplex screening in cancer. Cancer Res. 2000 Jul 15; 60(14):3732-7. PMID: 10919642.
    Citations: 4     Fields:    Translation:HumansCells
  88. Chakrabarti S, Mahmood A, Makrigiorgos GM. Fluorescent labelling of closely-spaced aldehydes induced in DNA by bleomycin-Fe(III). Int J Radiat Biol. 1999 Aug; 75(8):1055-65. PMID: 10465372.
    Citations: 1     Fields:    Translation:AnimalsCells
  89. Maulik G, Botchway S, Chakrabarti S, Tetradis S, Price B, Makrigiorgos GM. Novel non-isotopic detection of MutY enzyme-recognized mismatches in DNA via ultrasensitive detection of aldehydes. Nucleic Acids Res. 1999 Mar 01; 27(5):1316-22. PMID: 9973620.
    Citations: 2     Fields:    Translation:AnimalsCells
  90. Makrigiorgos GM. Detection of chromatin-associated hydroxyl radicals generated by DNA-bound metal compounds and antitumor antibiotics. Met Ions Biol Syst. 1999; 36:521-45. PMID: 10093935.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  91. Maulik G, Kassis AI, Savvides P, Makrigiorgos GM. Fluoresceinated phosphoethanolamine for flow-cytometric measurement of lipid peroxidation. Free Radic Biol Med. 1998 Oct; 25(6):645-53. PMID: 9801063.
    Citations: 1     Fields:    Translation:AnimalsCells
  92. Makrigiorgos GM, Chakrabarti S, Mahmood A. Fluorescent labelling of abasic sites: a novel methodology to detect closely-spaced damage sites in DNA. Int J Radiat Biol. 1998 Jul; 74(1):99-109. PMID: 9687979.
    Citations: 3     Fields:    Translation:Cells
  93. Kassis AI, Wen PY, Van den Abbeele AD, Baranowska-Kortylewicz J, Makrigiorgos GM, Metz KR, Matalka KZ, Cook CU, Sahu SK, Black PM, Adelstein SJ. 5-[125I]iodo-2'-deoxyuridine in the radiotherapy of brain tumors in rats. J Nucl Med. 1998 Jul; 39(7):1148-54. PMID: 9669385.
    Citations: 6     Fields:    Translation:Animals
  94. Botchway SW, Chakrabarti S, Makrigiorgos GM. Novel visible and ultraviolet light photogeneration of hydroxyl radicals by 2-methyl-4-nitro-quinoline-N-oxide (MNO) and 4,4'-dinitro-(2,2')bipyridinyl-N,N'-dioxide (DBD). Photochem Photobiol. 1998 Jun; 67(6):635-40. PMID: 9648528.
    Citations: 1     Fields:    Translation:Cells
  95. Chakrabarti S, Kassis AI, Slayter HS, Bump EA, Sahu SK, Makrigiorgos GM. Continuous detection of radiation or metal generated hydroxyl radicals within core chromatin particles. Int J Radiat Biol. 1998 Jan; 73(1):53-63. PMID: 9464477.
    Citations: 1     Fields:    Translation:AnimalsCells
  96. Makrigiorgos GM. Detection of lipid peroxidation on erythrocytes using the excimer-forming property of a lipophilic BODIPY fluorescent dye. J Biochem Biophys Methods. 1997 Aug 01; 35(1):23-35. PMID: 9310865.
    Citations: 5     Fields:    Translation:HumansCells
  97. Makrigiorgos GM, Kassis AI, Mahmood A, Bump EA, Savvides P. Novel fluorescein-based flow-cytometric method for detection of lipid peroxidation. Free Radic Biol Med. 1997; 22(1-2):93-100. PMID: 8958133.
    Citations: 2     Fields:    Translation:HumansCells
  98. Chakrabarti S, Mahmood A, Kassis AI, Bump EA, Jones AG, Makrigiorgos GM. Generation of hydroxyl radicals by nucleohistone-bound metal-adriamycin complexes. Free Radic Res. 1996 Sep; 25(3):207-20. PMID: 8889487.
    Citations: 1     Fields:    Translation:Cells
  99. Chakrabarti S, Makrigiorgos GM, O'Brien K, Bump E, Kassis AI. Measurement of hydroxyl radicals catalyzed in the immediate vicinity of DNA by metal-bleomycin complexes. Free Radic Biol Med. 1996; 20(6):777-83. PMID: 8728024.
    Citations: 3     Fields:    
  100. Makrigiorgos GM, Bump E, Huang C, Baranowska-Kortylewicz J, Kassis AI. A fluorimetric method for the detection of copper-mediated hydroxyl free radicals in the immediate proximity of DNA. Free Radic Biol Med. 1995 Apr; 18(4):669-78. PMID: 7750791.
    Citations: 1     Fields:    Translation:Animals
  101. Sahu SK, Kassis AI, Makrigiorgos GM, Baranowska-Kortylewicz J, Adelstein SJ. The effects of indium-111 decay on pBR322 DNA. Radiat Res. 1995 Feb; 141(2):193-8. PMID: 7838958.
    Citations: 2     Fields:    Translation:Cells
  102. Collins AK, Makrigiorgos GM, Svensson GK. Coumarin chemical dosimeter for radiation therapy. Med Phys. 1994 Nov; 21(11):1741-7. PMID: 7891636.
    Citations: 5     Fields:    Translation:Humans
  103. Makrigiorgos GM, Bump E, Huang C, Baranowska-Kortylewicz J, Kassis AI. Accessibility of nucleic acid-complexed biomolecules to hydroxyl radicals correlates with their conformation: a fluorescence polarization spectroscopy study. Int J Radiat Biol. 1994 Sep; 66(3):247-57. PMID: 7930827.
    Citations:    Fields:    Translation:Cells
  104. Makrigiorgos GM, Folkard M, Huang C, Bump E, Baranowska-Kortylewicz J, Sahu SK, Michael BD, Kassis AI. Quantification of radiation-induced hydroxyl radicals within nucleohistones using a molecular fluorescent probe. Radiat Res. 1994 May; 138(2):177-85. PMID: 8183987.
    Citations: 1     Fields:    Translation:Animals
  105. Makrigiorgos GM, Baranowska-Kortylewicz J, Bump E, Sahu SK, Berman RM, Kassis AI. A method for detection of hydroxyl radicals in the vicinity of biomolecules using radiation-induced fluorescence of coumarin. Int J Radiat Biol. 1993 Apr; 63(4):445-58. PMID: 8096857.
    Citations: 4     Fields:    Translation:Humans
  106. Makrigiorgos GM, Berman RM, Baranowska-Kortylewicz J, Bump E, Humm JL, Adelstein SJ, Kassis AI. DNA damage produced in V79 cells by DNA-incorporated iodine-123: a comparison with iodine-125. Radiat Res. 1992 Mar; 129(3):309-14. PMID: 1542718.
    Citations: 5     Fields:    Translation:AnimalsCells
  107. Baranowska-Kortylewicz J, Makrigiorgos GM, Van den Abbeele AD, Berman RM, Adelstein SJ, Kassis AI. 5-[123I]iodo-2'-deoxyuridine in the radiotherapy of an early ascites tumor model. Int J Radiat Oncol Biol Phys. 1991 Nov; 21(6):1541-51. PMID: 1938564.
    Citations: 8     Fields:    Translation:Animals
  108. Makrigiorgos GM, Adelstein SJ, Kassis AI. Cellular radiation dosimetry and its implications for estimation of radiation risks. Illustrative results with technetium 99m-labeled microspheres and macroaggregates. JAMA. 1990 Aug 01; 264(5):592-5. PMID: 2366298.
    Citations: 7     Fields:    Translation:HumansPHPublic Health
  109. Makrigiorgos GM, Ito S, Baranowska-Kortylewicz J, Vinter DW, Iqbal A, Van den Abbeele AD, Adelstein SJ, Kassis AI. Inhomogeneous deposition of radiopharmaceuticals at the cellular level: experimental evidence and dosimetric implications. J Nucl Med. 1990 Aug; 31(8):1358-63. PMID: 2384804.
    Citations: 7     Fields:    Translation:Animals
  110. Makrigiorgos GM, Smathers JB, Myers LT, Benedict SH. Radiation quality investigations around a neutron therapy beam, using a high-pressure ionization chamber. Med Phys. 1990 Jan-Feb; 17(1):84-6. PMID: 2106613.
    Citations:    Fields:    Translation:Humans
  111. Makrigiorgos G, Adelstein SJ, Kassis AI. Auger electron emitters: insights gained from in vitro experiments. Radiat Environ Biophys. 1990; 29(2):75-91. PMID: 2187215.
    Citations: 3     Fields:    Translation:Humans
  112. Makrigiorgos GM, Adelstein SJ, Kassis AI. Limitations of conventional internal dosimetry at the cellular level. J Nucl Med. 1989 Nov; 30(11):1856-64. PMID: 2809750.
    Citations: 9     Fields:    Translation:Cells
  113. Makrigiorgos GM. Derivation of radiation quality average parameters in neutron-gamma radiation fields with the high-pressure ionization chamber: theory and practice. Radiat Res. 1989 Jun; 118(3):387-400. PMID: 2727266.
    Citations:    Fields:    Translation:Cells
  114. Makrigiorgos GM, Kassis AI, Baranowska-Kortylewicz J, McElvany KD, Welch MJ, Sastry KS, Adelstein SJ. Radiotoxicity of 5-[123I]iodo-2'-deoxyuridine in V79 cells: a comparison with 5-[125I]iodo-2'-deoxyuridine. Radiat Res. 1989 Jun; 118(3):532-44. PMID: 2727274.
    Citations: 15     Fields:    Translation:AnimalsCells
  115. Folkard M, Makrigiorgos G, Roper MJ, Waker AJ, Michael BD. Measurements of neutron energy using a recoil-proton telescope and a high-pressure ionization chamber. Radiat Res. 1989 Apr; 118(1):37-45. PMID: 2704790.
    Citations:    Fields:    
  116. Makrigiorgos G, Antonadou D, Proukakis C, Throuvalas N. Measurement of the restricted linear energy transfer of stray radiation close to the treatment volume of 12 and 18 MeV clinical photon beams. Med Phys. 1989 Mar-Apr; 16(2):302-4. PMID: 2497319.
    Citations:    Fields:    Translation:HumansCells
  117. Lymberis C, Makrigiorgos G, Sbonias E, Polizois E, Mortzos G, Bacas A, Fountos A. Radiocesium levels in human muscle samples in Greece one year after the Chernobyl accident. Int J Rad Appl Instrum A. 1988; 39(2):175-6. PMID: 2833472.
    Citations:    Fields:    Translation:Humans
  118. Makrigiorgos G. Characteristics of an ethylene-polyethylene high-pressure ionization chamber and its potential for deriving radiation dose and quality information in neutron-gamma radiation fields. Med Phys. 1988 Jan-Feb; 15(1):36-9. PMID: 3352549.
    Citations:    Fields:    Translation:Humans
  119. Makrigiorgos G, Antonadou D. Measurement of the restricted dose mean LET outside the primary beam of a 60Co radiotherapy unit. Radiat Res. 1987 Apr; 110(1):142-8. PMID: 3562790.
    Citations:    Fields:    Translation:CellsPHPublic Health
  120. Makrigiorgos G, Waker AJ. The measurement of absorbed dose and dose-equivalent levels for in vivo neutron activation analysis. Phys Med Biol. 1985 Sep; 30(9):909-19. PMID: 4048275.
    Citations:    Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.