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Claudio Vinegoni, Ph.D.

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Our laboratory employs optical imaging techniques such as confocal/multiphoton microscopy, optical projection tomography, two photon fluorescence polarization microscopy to investigate systems biology and to image in vivo drug-target engagement. We develop image processing stabilization techniques for artifact removals for heart imaging and intraoperative imaging in general. We develop also novel optical imaging techniques in combination with novel processing platforms for molecular imaging and high throughput screening.

keywords: multiphoton imaging, two photon fluorescence polarization imaging, in vivo imaging, window chambers, imaging pharmacodynamics, drug-target engagement imaging

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Herisson F, Frodermann V, Courties G, Rohde D, Sun Y, Vandoorne K, Wojtkiewicz GR, Masson GS, Vinegoni C, Kim J, Kim DE, Weissleder R, Swirski FK, Moskowitz MA, Nahrendorf M. Direct vascular channels connect skull bone marrow and the brain surface enabling myeloid cell migration. Nat Neurosci. 2018 Sep; 21(9):1209-1217. PMID: 30150661.
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  2. Vandoorne K, Rohde D, Kim HY, Courties G, Wojtkiewicz G, Honold L, Hoyer FF, Frodermann V, Nayar R, Herisson F, Jung Y, Désogère PA, Vinegoni C, Caravan P, Weissleder R, Sosnovik DE, Lin CP, Swirski FK, Nahrendorf M. Imaging the Vascular Bone Marrow Niche During Inflammatory Stress. Circ Res. 2018 Aug 03; 123(4):415-427. PMID: 29980569.
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  3. Vinegoni C, Feruglio PF, Gryczynski I, Mazitschek R, Weissleder R. Fluorescence anisotropy imaging in drug discovery. Adv Drug Deliv Rev. 2018 Feb 02. PMID: 29410158.
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  4. Hulsmans M, Sager HB, Roh JD, Valero-Muñoz M, Houstis NE, Iwamoto Y, Sun Y, Wilson RM, Wojtkiewicz G, Tricot B, Osborne MT, Hung J, Vinegoni C, Naxerova K, Sosnovik DE, Zile MR, Bradshaw AD, Liao R, Tawakol A, Weissleder R, Rosenzweig A, Swirski FK, Sam F, Nahrendorf M. Cardiac macrophages promote diastolic dysfunction. J Exp Med. 2018 Feb 05; 215(2):423-440. PMID: 29339450.
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  5. Vinegoni C, Fumene Feruglio P, Brand C, Lee S, Nibbs AE, Stapleton S, Shah S, Gryczynski I, Reiner T, Mazitschek R, Weissleder R. Measurement of drug-target engagement in live cells by two-photon fluorescence anisotropy imaging. Nat Protoc. 2017 Jul; 12(7):1472-1497. PMID: 28686582.
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  6. Hulsmans M, Clauss S, Xiao L, Aguirre AD, King KR, Hanley A, Hucker WJ, Wülfers EM, Seemann G, Courties G, Iwamoto Y, Sun Y, Savol AJ, Sager HB, Lavine KJ, Fishbein GA, Capen DE, Da Silva N, Miquerol L, Wakimoto H, Seidman CE, Seidman JG, Sadreyev RI, Naxerova K, Mitchell RN, Brown D, Libby P, Weissleder R, Swirski FK, Kohl P, Vinegoni C, Milan DJ, Ellinor PT, Nahrendorf M. Macrophages Facilitate Electrical Conduction in the Heart. Cell. 2017 04 20; 169(3):510-522.e20. PMID: 28431249.
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  7. Seo KJ, Qiang Y, Bilgin I, Kar S, Vinegoni C, Weissleder R, Fang H. Transparent Electrophysiology Microelectrodes and Interconnects from Metal Nanomesh. ACS Nano. 2017 04 25; 11(4):4365-4372. PMID: 28391679.
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  8. Mikula H, Stapleton S, Kohler RH, Vinegoni C, Weissleder R. Design and Development of Fluorescent Vemurafenib Analogs for In Vivo Imaging. Theranostics. 2017; 7(5):1257-1265. PMID: 28435463.
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  9. Lee S, Courties G, Nahrendorf M, Weissleder R, Vinegoni C. Motion characterization scheme to minimize motion artifacts in intravital microscopy. J Biomed Opt. 2017 03 01; 22(3):36005. PMID: 28253383.
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  10. Dubach JM, Kim E, Yang K, Cuccarese M, Giedt RJ, Meimetis LG, Vinegoni C, Weissleder R. Quantitating drug-target engagement in single cells in vitro and in vivo. Nat Chem Biol. 2017 02; 13(2):168-173. PMID: 27918558.
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  11. Giedt RJ, Fumene Feruglio P, Pathania D, Yang KS, Kilcoyne A, Vinegoni C, Mitchison TJ, Weissleder R. Computational imaging reveals mitochondrial morphology as a biomarker of cancer phenotype and drug response. Sci Rep. 2016 09 09; 6:32985. PMID: 27609668.
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  12. Sager HB, Dutta P, Dahlman JE, Hulsmans M, Courties G, Sun Y, Heidt T, Vinegoni C, Borodovsky A, Fitzgerald K, Wojtkiewicz GR, Iwamoto Y, Tricot B, Khan OF, Kauffman KJ, Xing Y, Shaw TE, Libby P, Langer R, Weissleder R, Swirski FK, Anderson DG, Nahrendorf M. RNAi targeting multiple cell adhesion molecules reduces immune cell recruitment and vascular inflammation after myocardial infarction. Sci Transl Med. 2016 06 08; 8(342):342ra80. PMID: 27280687.
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  13. Vinegoni C, Leon Swisher C, Fumene Feruglio P, Giedt RJ, Rousso DL, Stapleton S, Weissleder R. Real-time high dynamic range laser scanning microscopy. Nat Commun. 2016 Apr 01; 7:11077. PMID: 27032979; PMCID: PMC4821995.
  14. Vinegoni C, Dubach JM, Feruglio PF, Weissleder R. Two-photon Fluorescence Anisotropy Microscopy for Imaging and Direct Measurement of Intracellular Drug Target Engagement. IEEE J Sel Top Quantum Electron. 2016 May-Jun; 22(3). PMID: 27440991.
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  15. Roy J, Kim B, Hill E, Visconti P, Krapf D, Vinegoni C, Weissleder R, Brown D, Breton S. Tyrosine kinase-mediated axial motility of basal cells revealed by intravital imaging. Nat Commun. 2016 Feb 12; 7:10666. PMID: 26868824; PMCID: PMC4754344.
  16. Vinegoni C, Aguirre AD, Lee S, Weissleder R. Imaging the beating heart in the mouse using intravital microscopy techniques. Nat Protoc. 2015 Nov; 10(11):1802-19. PMID: 26492138.
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  17. Clardy SM, Mohan JF, Vinegoni C, Keliher EJ, Iwamoto Y, Benoist C, Mathis D, Weissleder R. Rapid, high efficiency isolation of pancreatic ß-cells. Sci Rep. 2015 Sep 02; 5:13681. PMID: 26330153; PMCID: PMC4557033.
  18. Vinegoni C, Dubach JM, Thurber GM, Miller MA, Mazitschek R, Weissleder R. Advances in measuring single-cell pharmacology in vivo. Drug Discov Today. 2015 Sep; 20(9):1087-92. PMID: 26024776; PMCID: PMC4567932.
  19. Vinegoni C, Lee S, Aguirre AD, Weissleder R. New techniques for motion-artifact-free in vivo cardiac microscopy. Front Physiol. 2015; 6:147. PMID: 26029116; PMCID: PMC4428079.
  20. Dutta P, Sager HB, Stengel KR, Naxerova K, Courties G, Saez B, Silberstein L, Heidt T, Sebas M, Sun Y, Wojtkiewicz G, Feruglio PF, King K, Baker JN, van der Laan AM, Borodovsky A, Fitzgerald K, Hulsmans M, Hoyer F, Iwamoto Y, Vinegoni C, Brown D, Di Carli M, Libby P, Hiebert SW, Scadden DT, Swirski FK, Weissleder R, Nahrendorf M. Myocardial Infarction Activates CCR2(+) Hematopoietic Stem and Progenitor Cells. Cell Stem Cell. 2015 May 07; 16(5):477-87. PMID: 25957903.
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  21. Dubach JM, Vinegoni C, Weissleder R. Steady state anisotropy two-photon microscopy resolves multiple, spectrally similar fluorophores, enabling in vivo multilabel imaging. Opt Lett. 2014 Aug 01; 39(15):4482-5. PMID: 25078208; PMCID: PMC4341989.
  22. Aguirre AD, Vinegoni C, Sebas M, Weissleder R. Intravital imaging of cardiac function at the single-cell level. Proc Natl Acad Sci U S A. 2014 Aug 05; 111(31):11257-62. PMID: 25053815; PMCID: PMC4128110.
  23. Heidt T, Sager HB, Courties G, Dutta P, Iwamoto Y, Zaltsman A, von Zur Muhlen C, Bode C, Fricchione GL, Denninger J, Lin CP, Vinegoni C, Libby P, Swirski FK, Weissleder R, Nahrendorf M. Chronic variable stress activates hematopoietic stem cells. Nat Med. 2014 Jul; 20(7):754-758. PMID: 24952646; PMCID: PMC4087061.
  24. Dubach JM, Vinegoni C, Mazitschek R, Fumene Feruglio P, Cameron LA, Weissleder R. In vivo imaging of specific drug-target binding at subcellular resolution. Nat Commun. 2014 May 28; 5:3946. PMID: 24867710; PMCID: PMC4362617.
  25. Lee S, Vinegoni C, Sebas M, Weissleder R. Automated motion artifact removal for intravital microscopy, without a priori information. Sci Rep. 2014 Mar 28; 4:4507. PMID: 24676021; PMCID: PMC3968488.
  26. Vinegoni C, Lee S, Feruglio PF, Weissleder R. Advanced Motion Compensation Methods for Intravital Optical Microscopy. IEEE J Sel Top Quantum Electron. 2014 Mar; 20(2). PMID: 24273405.
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  27. Vinegoni C, Lee S, Feruglio PF, Marzola P, Nahrendorf M, Weissleder R. Sequential average segmented microscopy for high signal-to-noise ratio motion-artifact-free in vivo heart imaging. Biomed Opt Express. 2013; 4(10):2095-106. PMID: 24156067; PMCID: PMC3799669.
  28. Lee J, Li M, Milwid J, Dunham J, Vinegoni C, Gorbatov R, Iwamoto Y, Wang F, Shen K, Hatfield K, Enger M, Shafiee S, McCormack E, Ebert BL, Weissleder R, Yarmush ML, Parekkadan B. Implantable microenvironments to attract hematopoietic stem/cancer cells. Proc Natl Acad Sci U S A. 2012 Nov 27; 109(48):19638-43. PMID: 23150542; PMCID: PMC3511730.
  29. Vinegoni C, Lee S, Gorbatov R, Weissleder R. Motion compensation using a suctioning stabilizer for intravital microscopy. Intravital. 2012 Oct 01; 1(2):115-121. PMID: 24086796.
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  30. Lee S, Vinegoni C, Feruglio PF, Weissleder R. Improved intravital microscopy via synchronization of respiration and holder stabilization. J Biomed Opt. 2012 Sep; 17(9):96018-1. PMID: 23085919; PMCID: PMC3449295.
  31. Lu X, Agasti SS, Vinegoni C, Waterman P, DePinho RA, Weissleder R. Optochemogenetics (OCG) allows more precise control of genetic engineering in mice with CreER regulators. Bioconjug Chem. 2012 Sep 19; 23(9):1945-51. PMID: 22917215; PMCID: PMC3775343.
  32. Feruglio PF, Vinegoni C, Fexon L, Thurber G, Sbarbati A, Weissleder R. Noise suppressed, multifocus image fusion for enhanced intraoperative navigation. J Biophotonics. 2013 Apr; 6(4):363-70. PMID: 22887724; PMCID: PMC3779878.
  33. Dutta P, Courties G, Wei Y, Leuschner F, Gorbatov R, Robbins CS, Iwamoto Y, Thompson B, Carlson AL, Heidt T, Majmudar MD, Lasitschka F, Etzrodt M, Waterman P, Waring MT, Chicoine AT, van der Laan AM, Niessen HW, Piek JJ, Rubin BB, Butany J, Stone JR, Katus HA, Murphy SA, Morrow DA, Sabatine MS, Vinegoni C, Moskowitz MA, Pittet MJ, Libby P, Lin CP, Swirski FK, Weissleder R, Nahrendorf M. Myocardial infarction accelerates atherosclerosis. Nature. 2012 Jul 19; 487(7407):325-9. PMID: 22763456; PMCID: PMC3401326.
  34. Yang KS, Budin G, Reiner T, Vinegoni C, Weissleder R. Bioorthogonal imaging of aurora kinase A in live cells. Angew Chem Int Ed Engl. 2012 Jul 02; 51(27):6598-603. PMID: 22644700; PMCID: PMC3523717.
  35. Earley S, Vinegoni C, Dunham J, Gorbatov R, Feruglio PF, Weissleder R. In vivo imaging of drug-induced mitochondrial outer membrane permeabilization at single-cell resolution. Cancer Res. 2012 Jun 15; 72(12):2949-56. PMID: 22505651; PMCID: PMC3603290.
  36. Vinegoni C, Fumene Feruglio P, Razansky D, Gorbatov R, Ntziachristos V, Sbarbati A, Nahrendorf M, Weissleder R. Mapping molecular agents distributions in whole mice hearts using born-normalized optical projection tomography. PLoS One. 2012; 7(4):e34427. PMID: 22509302.
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  37. Razansky D, Deliolanis NC, Vinegoni C, Ntziachristos V. Deep tissue optical and optoacoustic molecular imaging technologies for pre-clinical research and drug discovery. Curr Pharm Biotechnol. 2012 Mar; 13(4):504-22. PMID: 22216767.
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  38. Reiner T, Lacy J, Keliher EJ, Yang KS, Ullal A, Kohler RH, Vinegoni C, Weissleder R. Imaging therapeutic PARP inhibition in vivo through bioorthogonally developed companion imaging agents. Neoplasia. 2012 Mar; 14(3):169-77. PMID: 22496617; PMCID: PMC3323895.
  39. Lee WW, Marinelli B, van der Laan AM, Sena BF, Gorbatov R, Leuschner F, Dutta P, Iwamoto Y, Ueno T, Begieneman MP, Niessen HW, Piek JJ, Vinegoni C, Pittet MJ, Swirski FK, Tawakol A, Di Carli M, Weissleder R, Nahrendorf M. PET/MRI of inflammation in myocardial infarction. J Am Coll Cardiol. 2012 Jan 10; 59(2):153-63. PMID: 22222080; PMCID: PMC3257823.
  40. Lee S, Vinegoni C, Feruglio PF, Fexon L, Gorbatov R, Pivoravov M, Sbarbati A, Nahrendorf M, Weissleder R. Real-time in vivo imaging of the beating mouse heart at microscopic resolution. Nat Commun. 2012; 3:1054. PMID: 22968700; PMCID: PMC3622400.
  41. Haase A, Rigosi E, Frasnelli E, Trona F, Tessarolo F, Vinegoni C, Anfora G, Vallortigara G, Antolini R. A multimodal approach for tracing lateralisation along the olfactory pathway in the honeybee through electrophysiological recordings, morpho-functional imaging, and behavioural studies. Eur Biophys J. 2011 Nov; 40(11):1247-58. PMID: 21956452; PMCID: PMC3366498.
  42. Reiner T, Thurber G, Gaglia J, Vinegoni C, Liew CW, Upadhyay R, Kohler RH, Li L, Kulkarni RN, Benoist C, Mathis D, Weissleder R. Accurate measurement of pancreatic islet beta-cell mass using a second-generation fluorescent exendin-4 analog. Proc Natl Acad Sci U S A. 2011 Aug 02; 108(31):12815-20. PMID: 21768367; PMCID: PMC3150928.
  43. Vinegoni C, Botnaru I, Aikawa E, Calfon MA, Iwamoto Y, Folco EJ, Ntziachristos V, Weissleder R, Libby P, Jaffer FA. Indocyanine green enables near-infrared fluorescence imaging of lipid-rich, inflamed atherosclerotic plaques. Sci Transl Med. 2011 May 25; 3(84):84ra45. PMID: 21613624; PMCID: PMC3112179.
  44. Rigosi E, Frasnelli E, Vinegoni C, Antolini R, Anfora G, Vallortigara G, Haase A. Searching for anatomical correlates of olfactory lateralization in the honeybee antennal lobes: a morphological and behavioural study. Behav Brain Res. 2011 Aug 01; 221(1):290-4. PMID: 21402106; PMCID: PMC3089663.
  45. Figueiredo JL, Nahrendorf M, Vinegoni C, Weissleder R. Intraoperative near-infrared fluorescent cholangiography (NIRFC) in mouse models of bile duct injury: reply. World J Surg. 2011 Mar; 35(3):694-5. PMID: 20645091.
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  46. A Haase, E Rigosi, E Frasnelli, F Trona, F Tessarolo, C Vinegoni, G Anfora, G Vallortigara, R Antolini. A multimodal approach for tracing lateralization along the olfactory pathway in the honeybee through electrophysiological recordings, morpho-functional imaging, and behavioural studies. Europ. Biophysics J. 2011.
  47. Haase A, Rigosi E, Trona F, Anfora G, Vallortigara G, Antolini R, Vinegoni C. In-vivo two-photon imaging of the honey bee antennal lobe. Biomed Opt Express. 2010 Dec 16; 2(1):131-8. PMID: 21326643; PMCID: PMC3028488.
  48. Gros J, Hu JK, Vinegoni C, Feruglio PF, Weissleder R, Tabin CJ. WNT5A/JNK and FGF/MAPK pathways regulate the cellular events shaping the vertebrate limb bud. Curr Biol. 2010 Nov 23; 20(22):1993-2002. PMID: 21055947; PMCID: PMC2998074.
  49. Fumene Feruglio P, Vinegoni C, Gros J, Sbarbati A, Weissleder R. Block matching 3D random noise filtering for absorption optical projection tomography. Phys Med Biol. 2010 Sep 21; 55(18):5401-15. PMID: 20736500; PMCID: PMC2934766.
  50. Nahrendorf M, Keliher E, Marinelli B, Waterman P, Feruglio PF, Fexon L, Pivovarov M, Swirski FK, Pittet MJ, Vinegoni C, Weissleder R. Hybrid PET-optical imaging using targeted probes. Proc Natl Acad Sci U S A. 2010 Apr 27; 107(17):7910-5. PMID: 20385821; PMCID: PMC2867879.
  51. Vinegoni C, Fumene Feruglio P, Cortez-Retamozo V, Razansky D, Medoff BD, Ntziachristos V, Sbarbati A, Pittet M, Weissleder R. Imaging of molecular probe activity with Born-normalized fluorescence optical projection tomography. Opt Lett. 2010 Apr 01; 35(7):1088-90. PMID: 20364226; PMCID: PMC2900933.
  52. Calfon MA, Vinegoni C, Ntziachristos V, Jaffer FA. Intravascular near-infrared fluorescence molecular imaging of atherosclerosis: toward coronary arterial visualization of biologically high-risk plaques. J Biomed Opt. 2010 Jan-Feb; 15(1):011107. PMID: 20210433; PMCID: PMC3188610.
  53. Vinegoni C, Fexon L, Feruglio PF, Pivovarov M, Figueiredo JL, Nahrendorf M, Pozzo A, Sbarbati A, Weissleder R. High throughput transmission optical projection tomography using low cost graphics processing unit. Opt Express. 2009 Dec 07; 17(25):22320-32. PMID: 20052155; PMCID: PMC2805020.
  54. Tsai CC, Vinegoni C, Weissleder R. Diffractionless beam in free space with adiabatic changing refractive index in a single mode tapered slab waveguide. Opt Express. 2009 Nov 23; 17(24):21723-31. PMID: 19997414; PMCID: PMC2805120.
  55. Vinegoni C, Razansky D, Hilderbrand SA, Shao F, Ntziachristos V, Weissleder R. Transillumination fluorescence imaging in mice using biocompatible upconverting nanoparticles. Opt Lett. 2009 Sep 01; 34(17):2566-8. PMID: 19724491; PMCID: PMC2749971.
  56. Vinegoni C, Razansky D, Pitsouli C, Perrimon N, Ntziachristos V, Weissleder R. Mesoscopic fluorescence tomography for in-vivo imaging of developing Drosophila. J Vis Exp. 2009 Aug 20; (30). PMID: 19696720; PMCID: PMC2736679.
  57. Vinegoni C, Razansky D, Figueiredo JL, Fexon L, Pivovarov M, Nahrendorf M, Ntziachristos V, Weissleder R. Born normalization for fluorescence optical projection tomography for whole heart imaging. J Vis Exp. 2009 Jun 02; (28). PMID: 19578329; PMCID: PMC2794886.
  58. Razansky D, Vinegoni C, Ntziachristos V. Imaging of mesoscopic-scale organisms using selective-plane optoacoustic tomography. Phys Med Biol. 2009 May 07; 54(9):2769-77. PMID: 19369709.
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  59. Vinegoni C, Razansky D, Figueiredo JL, Nahrendorf M, Ntziachristos V, Weissleder R. Normalized Born ratio for fluorescence optical projection tomography. Opt Lett. 2009 Feb 01; 34(3):319-21. PMID: 19183644; PMCID: PMC2771918.
  60. D. Razansky, C. Vinegoni, et al. . Multispectral opto-acoustic tomography of deep-seated fluorescent proteins in vivo. Nature Photonics. 2009; 3:412-417.
  61. Cortez-Retamozo V, Swirski FK, Waterman P, Yuan H, Figueiredo JL, Newton AP, Upadhyay R, Vinegoni C, Kohler R, Blois J, Smith A, Nahrendorf M, Josephson L, Weissleder R, Pittet MJ. Real-time assessment of inflammation and treatment response in a mouse model of allergic airway inflammation. J Clin Invest. 2008 Dec; 118(12):4058-66. PMID: 19033674; PMCID: PMC2579705.
  62. Razansky D, Vinegoni C, Ntziachristos V. Polarization-sensitive optoacoustic tomography of optically diffuse tissues. Opt Lett. 2008 Oct 15; 33(20):2308-10. PMID: 18923605.
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  63. Jaffer FA, Vinegoni C, John MC, Aikawa E, Gold HK, Finn AV, Ntziachristos V, Libby P, Weissleder R. Real-time catheter molecular sensing of inflammation in proteolytically active atherosclerosis. Circulation. 2008 Oct 28; 118(18):1802-9. PMID: 18852366; PMCID: PMC2729441.
  64. Vinegoni C, Pitsouli C, Razansky D, Perrimon N, Ntziachristos V. In vivo imaging of Drosophila melanogaster pupae with mesoscopic fluorescence tomography. Nat Methods. 2008 Jan; 5(1):45-7. PMID: 18066071.
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  65. Razansky D, Vinegoni C, Ntziachristos V. Multispectral photoacoustic imaging of fluorochromes in small animals. Opt Lett. 2007 Oct 01; 32(19):2891-3. PMID: 17909608.
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  66. Tan W, Vinegoni C, Norman JJ, Desai TA, Boppart SA. Imaging cellular responses to mechanical stimuli within three-dimensional tissue constructs. Microsc Res Tech. 2007 Apr; 70(4):361-71. PMID: 17262787.
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  67. D. Razansky, C. Vinegoni, and V. Ntziachristos. Multispectral photoacoustic imaging of fluorochromes in small animals. Opt. Lett. 2007; 32:2891.
  68. Jones GW, Marks DL, Vinegoni C, Boppart SA. High-spectral-resolution coherent anti-Stokes Raman scattering with interferometrically detected broadband chirped pulses. Opt Lett. 2006 May 15; 31(10):1543-5. PMID: 16642166.
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  69. Xu C, Vinegoni C, Ralston TS, Luo W, Tan W, Boppart SA. Spectroscopic spectral-domain optical coherence microscopy. Opt Lett. 2006 Apr 15; 31(8):1079-81. PMID: 16625909.
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  70. C. Vinegoni*,TS Ralston, Wei Luo, Wei Tan, SA Boppart . Integrated structural and functional imaging combining spectral-domain optical coherence and multiphoton microscopy. Appl Phys Lett. 2006; 88.
  71. Bredfeldt JS, Vinegoni C, Marks DL, Boppart SA. Molecularly sensitive optical coherence tomography. Opt Lett. 2005 Mar 01; 30(5):495-7. PMID: 15789714.
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  72. D.L. Marks, C. Vinegoni*,J. Bredfeldt, and SA Boppart . Nonlinear Interferometric Vibrational Imaging: Efficient Detection of Coherent Anti-Stokes Raman Scattering. OPN Special Issue. 2005; 16:23.
  73. Vinegoni C, Bredfeldt J, Marks D, Boppart S. Nonlinear optical contrast enhancement for optical coherence tomography. Opt Express. 2004 Jan 26; 12(2):331-41. PMID: 19471542.
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  74. Dan Marks*, C. Vinegoni*, J. Bredfeldt, and S.A. Boppart. Interferometric differentiation between resonant Coherent Anti-Stokes Raman Scattering and nonresonant four-wave-mixing processes. Appl Phys Lett. 2004; 85:5787.
  75. C. Vinegoni, M. Karlsson, M. Petersson, H. Sunnerud. Statistics of Polarization-dependent Loss in a Recirculating Loop. Journal of Lightwave Technology. 2004; 22:968.
  76. Marks DL, Vinegoni C, Bredfeldt JS, Boppart SA. Pulse shaping strategies for nonlinear interferometric vibrational imaging optimized for biomolecular imaging. Conf Proc IEEE Eng Med Biol Soc. 2004; 7:5300-3. PMID: 17271537.
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  77. M. Petersson, C. Vinegoni, H. Sunnerud, and M. Karlsson. Statistics of PMD in recirculating loops. Photonics and Technol. Lett. 2003; 15:1543.
  78. C. Vinegoni H. Chen, M. Leblanc, G.W. Schinn, M. Wegmuller, and N. Gisin. Distributed Measurements of Chromatic Dispersion and Nonlinear Coefficient in Low PMD Dispersion-Shifted Fibers. Photonics and Technol. Lett. 2003; 15:739.
  79. C. Vinegoni, M. Wegmuller, and N. Gisin. Measurements of the nonlinear coefficient of standard SMF, DSF, and DCF fibers using a self-aligned interferometer and a Faraday mirror. Photonics and Technol. Lett. 2001; 13:1337.
  80. M. Wegmuller, S. Demma, C. Vinegoni and N. Gisin. Emulator of First- and Second-order Polarization Mode Dispersion. Photonics and Technol. Lett. 2001; 14:630.
  81. C. Vinegoni, , M. Wegmuller, B. Huttner, N. Gisin. Measurement of nonlinear polarization rotation in a highly birefringent optical fiber using a Faraday mirror. J Opt A. 2000; 2:314.
  82. C. Vinegoni, , M. Wegmuller, B. Huttner, N. Gisin. All optical switching in a highly birefringent and a standard telecom fiber using a Faraday mirror stabilization scheme. Opt. Comm. 2000; 182:312.
  83. E. Cazzanelli, G. Mariotto, C. Vinegoni, , A. Kuzmin and J. Purans. Color centers and polimorphysm in pure WO3 and mixed (1-x)WO3ReO2 powders. Ionics. 2000; 5:335.
  84. M. Wegmuller, P. Oberson, O. Guinnard, B.Huttner, L. Guinnard, C. Vinegoni, N. Gisin. Distributed gain measurements in Er-doped fibers with high resolution and accuracy using an Optical Frequency Domain Reflectometer. J. Lightwave Technol. 2000; 18:2127.
  85. F. Giorgis, C. Vinegoni, and L. Pavesi. Optical and photoluminescence properties of a-Si(1-x)Nx:H films deposited by PECVD. Phys Rev B. 2000; 61:4693.
  86. C. Vinegoni, M. Wegmuller, N. Gisin. Determination of the nonlinear coefficient n$_2$/A_{eff} using a self-aligned interferometer and a Faraday mirror. Electronic Letters. 2000; 36:886.
  87. M. Wegmuller, M. Legre, P. Oberson, O. Guinnard, L. Guinnard, C. Vinegoni, N. Gisin. Analysis of the polarization evolution in a ribbon cable using high resolution coherent OFDR. Photonics and Technology Lett. 2000; 13:145.
  88. C. Vinegoni, , M. Cazzanelli, A. Trivelli, G.J. Lunney, G. Mariotto and J. Levy. Morphological and optical characterization of GaN prepared by pulsed laser deposition. Surf. Coat. Technol. 2000; 124:272.
  89. V. Pellegrini, R. Colombelli, C. Vinegoni, , S. Rubini, R. Lantier, A. Franciosi, F. Beltram L. Pavesi . Resonant second harmonic generation in ZnSe microcavity. Appl. Phys. Lett. 1999; 74:1945.
  90. G. Mariotto, C. Vinegoni, , L.G. Jacobsohn and F.L. Freire Jr. Raman spectroscopy and scanning electron microscopy investigations of annealed amorphous carbon- germanium films deposited by dc-magnetron sputtering. Diamond and Related Materials. 1999; 23:668.
  91. E. Cazzanelli, C. Vinegoni, , G. Mariotto, A. Kuzmin and J. Purans. Low-Temperature polymorphism in tungsten trioxide powders and its dependence on mechanical treatment. J. Solid State Chem. 1999; 143:24.
  92. M. Cazzanelli, C. Vinegoni, , J.G. Lunney, K.P. O'Donnel, P.G. Middleton, C. Trager-Cowan and L.Pavesi. Luminescence properties of GaN thin films prepared by pulsed laser deposition. Mat. Sci. Eng. B. 1999; 59:137.
  93. F. Giorgis, C.F. Pirri, C. Vinegoni, and L. Pavesi. Luminescence processes in amorphous hydrogenated silicon-nitride nanometric multilayers. Physical Review B: Rapid Communications. 1999; 60:11572.
  94. E. Cazzanelli, C. Vinegoni, , G. Mariotto, A. Kuzmin and J. Purans. Raman study of the phase transitions sequence in pure WO3 at high temperature and in HxWO3 with variable hydrogen content. Solid State Ionics. 1999; 123:67.
  95. Temperature dependence of the photoluminescence of all silicon optical microcavities. J Appl Phys. 1999; 85:1760.
  96. M. Cazzanelli, C. Vinegoni, and L. Pavesi . Temperature dependence of the photoluminescence of all silicon optical microcavities. J Appl Phys. 1999; 85:1760.
  97. A. Kuzmin and J. Purans, E. Cazzanelli, C. Vinegoni, , G. Mariotto. XRD, EXAFS and Raman spectroscopy studies of pure ground WO3 and mixed W(1-x)RexO(3-y) policrystals. J. Appl. Physics. 1998; 84:5515.
  98. M. Cazzanelli, Duncan Cole, J.F. Donegan, James G. Lunney, P.G. Middleton K.P. O'Donnel, C. Vinegoni, L. Pavesi. Photoluminescence of localized excitons in pulsed laser deposited GaN. Appl. Phys. Lett. 1998; 73:3390.
  99. F. Giorgis, C.F. Pirri, C. Vinegoni, , L. Pavesi. Radiative emission properties of a-SiN:H based alloys, nanometric multilayers and light emitting devices. J. of Luminescence. 1998; 80:423.
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.