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Ingeborg Friehs, M.D.


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  1. K08HL075430 (FRIEHS, INGEBORG) Jan 1, 2005 - Dec 31, 2010
    Myocardial Hypertrophy and Therapeutic Angiogenesis
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Diaz-Gil D, Carreon CK, Silva-Gomez N, Benheim AE, Emani SM, Del Nido PJ, Marx GR, Friehs I. Case report: Active clinical manifestation of endocardial fibroelastosis in adolescence in a patient with mitral and aortic obstruction-histologic presence of endothelial-to-mesenchymal transformation. Front Cardiovasc Med. 2022; 9:1041039. PMID: 36531727; PMCID: PMC9749817.
  2. Vorisek CN, Zurakowski D, Tamayo A, Axt-Fliedner R, Siepmann T, Friehs I. Postnatal circulation in patients with aortic stenosis undergoing fetal aortic valvuloplasty: systematic review and meta-analysis. Ultrasound Obstet Gynecol. 2022 05; 59(5):576-584. PMID: 34726817.
    Citations: 2     Fields:    Translation:Humans
  3. Weixler V, Kramer P, Lindner J, Murin P, Cho MY, Del Nido P, Photiadis J, Friehs I. Endothelial-to-Mesenchymal Transition as Underlying Mechanism for the Formation of Double-Chambered Right Ventricle. Pediatr Cardiol. 2022 Jun; 43(5):1084-1093. PMID: 35084525; PMCID: PMC9098603.
    Citations:    Fields:    Translation:Humans
  4. Oh NA, Hong X, Doulamis IP, Meibalan E, Peiseler T, Melero-Martin J, García-Cardeña G, Del Nido PJ, Friehs I. Abnormal Flow Conditions Promote Endocardial Fibroelastosis Via Endothelial-to-Mesenchymal Transition, Which Is Responsive to Losartan Treatment. JACC Basic Transl Sci. 2021 Dec; 6(12):984-999. PMID: 35024504; PMCID: PMC8733675.
    Citations: 2     
  5. Vorisek C, Weixler V, Dominguez M, Axt-Fliedner R, Hammer PE, Lin RZ, Melero-Martin JM, Del Nido PJ, Friehs I. Mechanical strain triggers endothelial-to-mesenchymal transition of the endocardium in the immature heart. Pediatr Res. 2022 09; 92(3):721-728. PMID: 34837068; PMCID: PMC9133271.
    Citations:    Fields:    
  6. Hong X, Oh N, Wang K, Neumeyer J, Lee CN, Lin RZ, Piekarski B, Emani S, Greene AK, Friehs I, Del Nido PJ, Melero-Martin JM. Human endothelial colony-forming cells provide trophic support for pluripotent stem cell-derived cardiomyocytes via distinctively high expression of neuregulin-1. Angiogenesis. 2021 05; 24(2):327-344. PMID: 33454888; PMCID: PMC8337094.
    Citations: 2     Fields:    Translation:HumansCells
  7. Weixler V, Lapusca R, Grangl G, Guariento A, Saeed MY, Cowan DB, Del Nido PJ, McCully JD, Friehs I. Autogenous mitochondria transplantation for treatment of right heart failure. J Thorac Cardiovasc Surg. 2021 07; 162(1):e111-e121. PMID: 32919774.
    Citations: 8     Fields:    Translation:AnimalsCells
  8. Weixler V, Marx GR, Hammer PE, Emani SM, Del Nido PJ, Friehs I. Flow disturbances and the development of endocardial fibroelastosis. J Thorac Cardiovasc Surg. 2020 Feb; 159(2):637-646. PMID: 31668539.
    Citations: 7     Fields:    Translation:Humans
  9. Weixler V, Hammer PE, Marx GR, Emani SM, Del Nido PJ, Friehs I. Flow disturbances and progression of endocardial fibroelastosis - a case report. Cardiovasc Pathol. 2019 Sep - Oct; 42:1-3. PMID: 31150840.
    Citations: 2     Fields:    Translation:Humans
  10. Ramirez-Barbieri G, Moskowitzova K, Shin B, Blitzer D, Orfany A, Guariento A, Iken K, Friehs I, Zurakowski D, Del Nido PJ, McCully JD. Alloreactivity and allorecognition of syngeneic and allogeneic mitochondria. Mitochondrion. 2019 05; 46:103-115. PMID: 29588218.
    Citations: 21     Fields:    Translation:AnimalsCells
  11. Feins EN, Lee Y, O'Cearbhaill ED, Vasilyev NV, Shimada S, Friehs I, Perrin D, Hammer PE, Yamauchi H, Marx G, Gosline A, Arabagi V, Karp JM, Del Nido PJ. A Growth-Accommodating Implant for Paediatric Applications. Nat Biomed Eng. 2017; 1:818-825. PMID: 29900036.
    Citations: 5     Fields:    
  12. Wendell DC, Friehs I, Samyn MM, Harmann LM, LaDisa JF. Treating a 20 mm Hg gradient alleviates myocardial hypertrophy in experimental aortic coarctation. J Surg Res. 2017 10; 218:194-201. PMID: 28985849; PMCID: PMC5679105.
    Citations:    Fields:    Translation:Animals
  13. Illigens BM, Casar Berazaluce A, Poutias D, Gasser R, Del Nido PJ, Friehs I. Vascular Endothelial Growth Factor Prevents Endothelial-to-Mesenchymal Transition in Hypertrophy. Ann Thorac Surg. 2017 Sep; 104(3):932-939. PMID: 28483153; PMCID: PMC5572504.
    Citations: 8     Fields:    Translation:HumansAnimals
  14. Kaza AK, Wamala I, Friehs I, Kuebler JD, Rathod RH, Berra I, Ericsson M, Yao R, Thedsanamoorthy JK, Zurakowski D, Levitsky S, Del Nido PJ, Cowan DB, McCully JD. Myocardial rescue with autologous mitochondrial transplantation in a porcine model of ischemia/reperfusion. J Thorac Cardiovasc Surg. 2017 04; 153(4):934-943. PMID: 27938904.
    Citations: 47     Fields:    Translation:AnimalsCells
  15. Shimada S, Del Nido PJ, Friehs I. Development of a Vascularized Heterotopic Neonatal Rat Heart Transplantation Model. Eur Surg Res. 2016; 57(3-4):240-251. PMID: 27544776.
    Citations: 1     Fields:    Translation:Animals
  16. Siepmann T, Frenz E, Penzlin AI, Goelz S, Zago W, Friehs I, Kubasch ML, Wienecke M, Löhle M, Schrempf W, Barlinn K, Siegert J, Storch A, Reichmann H, Illigens BM. Pilomotor function is impaired in patients with Parkinson's disease: A study of the adrenergic axon-reflex response and autonomic functions. Parkinsonism Relat Disord. 2016 10; 31:129-134. PMID: 27569843.
    Citations: 6     Fields:    Translation:HumansCells
  17. Cowan DB, Yao R, Akurathi V, Snay ER, Thedsanamoorthy JK, Zurakowski D, Ericsson M, Friehs I, Wu Y, Levitsky S, Del Nido PJ, Packard AB, McCully JD. Intracoronary Delivery of Mitochondria to the Ischemic Heart for Cardioprotection. PLoS One. 2016; 11(8):e0160889. PMID: 27500955.
    Citations: 50     Fields:    Translation:HumansAnimalsCells
  18. Roche ET, Fabozzo A, Lee Y, Polygerinos P, Friehs I, Schuster L, Whyte W, Casar Berazaluce AM, Bueno A, Lang N, Pereira MJ, Feins E, Wasserman S, O'Cearbhaill ED, Vasilyev NV, Mooney DJ, Karp JM, Del Nido PJ, Walsh CJ. A light-reflecting balloon catheter for atraumatic tissue defect repair. Sci Transl Med. 2015 Sep 23; 7(306):306ra149. PMID: 26400910.
    Citations: 10     Fields:    Translation:Animals
  19. Shimada S, Robles C, Illigens BM, Casar Berazaluce AM, del Nido PJ, Friehs I. Distention of the Immature Left Ventricle Triggers Development of Endocardial Fibroelastosis: An Animal Model of Endocardial Fibroelastosis Introducing Morphopathological Features of Evolving Fetal Hypoplastic Left Heart Syndrome. Biomed Res Int. 2015; 2015:462469. PMID: 26064914.
    Citations: 5     Fields:    Translation:HumansAnimals
  20. Xu X, Friehs I, Zhong Hu T, Melnychenko I, Tampe B, Alnour F, Iascone M, Kalluri R, Zeisberg M, Del Nido PJ, Zeisberg EM. Endocardial fibroelastosis is caused by aberrant endothelial to mesenchymal transition. Circ Res. 2015 Feb 27; 116(5):857-66. PMID: 25587097; PMCID: PMC4344885.
    Citations: 37     Fields:    Translation:HumansAnimalsCells
  21. Yoshida T, Friehs I, Mummidi S, del Nido PJ, Addulnour-Nakhoul S, Delafontaine P, Valente AJ, Chandrasekar B. Pressure overload induces IL-18 and IL-18R expression, but markedly suppresses IL-18BP expression in a rabbit model. IL-18 potentiates TNF-a-induced cardiomyocyte death. J Mol Cell Cardiol. 2014 Oct; 75:141-51. PMID: 25108227.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  22. Lang N, Pereira MJ, Lee Y, Friehs I, Vasilyev NV, Feins EN, Ablasser K, O'Cearbhaill ED, Xu C, Fabozzo A, Padera R, Wasserman S, Freudenthal F, Ferreira LS, Langer R, Karp JM, del Nido PJ. A blood-resistant surgical glue for minimally invasive repair of vessels and heart defects. Sci Transl Med. 2014 Jan 08; 6(218):218ra6. PMID: 24401941.
    Citations: 57     Fields:    Translation:HumansAnimals
  23. Friehs I, Cowan DB, Choi YH, Black KM, Barnett R, Bhasin MK, Daly C, Dillon SJ, Libermann TA, McGowan FX, del Nido PJ, Levitsky S, McCully JD. Pressure-overload hypertrophy of the developing heart reveals activation of divergent gene and protein pathways in the left and right ventricular myocardium. Am J Physiol Heart Circ Physiol. 2013 Mar 01; 304(5):H697-708. PMID: 23262132.
    Citations: 11     Fields:    Translation:AnimalsCells
  24. Pereira MJ, Ouyang B, Sundback CA, Lang N, Friehs I, Mureli S, Pomerantseva I, McFadden J, Mochel MC, Mwizerwa O, Del Nido P, Sarkar D, Masiakos PT, Langer R, Ferreira LS, Karp JM. A highly tunable biocompatible and multifunctional biodegradable elastomer. Adv Mater. 2013 Feb 25; 25(8):1209-15. PMID: 23239051.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  25. Friehs I, Illigens B, Melnychenko I, Zhong-Hu T, Zeisberg E, Del Nido PJ. An animal model of endocardial fibroelastosis. J Surg Res. 2013 Jun 01; 182(1):94-100. PMID: 22938709.
    Citations: 9     Fields:    Translation:HumansAnimals
  26. Nikolova A, Ablasser K, Wyler von Ballmoos MC, Poutias D, Kaza E, McGowan FX, Moses MA, Del Nido PJ, Friehs I. Endogenous angiogenesis inhibitors prevent adaptive capillary growth in left ventricular pressure overload hypertrophy. Ann Thorac Surg. 2012 Nov; 94(5):1509-17. PMID: 22795062; PMCID: PMC3482283.
    Citations: 11     Fields:    Translation:Animals
  27. Hofstaetter JG, Blouin S, Friehs I, Klaushofer K, Roschger P. No effect of short-term hypertension on bone matrix mineralization in a surgical animal model in immature rabbits. Clin Exp Hypertens. 2012; 34(2):107-12. PMID: 21967032.
    Citations: 1     Fields:    Translation:Animals
  28. Kaza E, Ablasser K, Poutias D, Griffiths ER, Saad FA, Hofstaetter JG, del Nido PJ, Friehs I. Up-regulation of soluble vascular endothelial growth factor receptor-1 prevents angiogenesis in hypertrophied myocardium. Cardiovasc Res. 2011 Feb 01; 89(2):410-8. PMID: 20935166.
    Citations: 15     Fields:    Translation:AnimalsCells
  29. Griffiths ER, Friehs I, Scherr E, Poutias D, McGowan FX, Del Nido PJ. Electron transport chain dysfunction in neonatal pressure-overload hypertrophy precedes cardiomyocyte apoptosis independent of oxidative stress. J Thorac Cardiovasc Surg. 2010 Jun; 139(6):1609-17. PMID: 20038480; PMCID: PMC2875266.
    Citations: 15     Fields:    Translation:Animals
  30. Kitahori K, He H, Kawata M, Cowan DB, Friehs I, Del Nido PJ, McGowan FX. Development of left ventricular diastolic dysfunction with preservation of ejection fraction during progression of infant right ventricular hypertrophy. Circ Heart Fail. 2009 Nov; 2(6):599-607. PMID: 19919985.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  31. Choi YH, Cowan DB, Moran AM, Colan SD, Stamm C, Takeuchi K, Friehs I, del Nido PJ, McGowan FX. Myocyte apoptosis occurs early during the development of pressure-overload hypertrophy in infant myocardium. J Thorac Cardiovasc Surg. 2009 Jun; 137(6):1356-62, 1362.e1-3. PMID: 19464448; PMCID: PMC2758562.
    Citations: 9     Fields:    Translation:AnimalsCells
  32. Friehs I. Proteasome inhibition in hypertrophied myocardium. Am J Physiol Heart Circ Physiol. 2008 Oct; 295(4):H1373-4. PMID: 18708439.
    Citations: 2     Fields:    Translation:HumansAnimals
  33. Barillas R, Friehs I, Cao-Danh H, Martinez JF, del Nido PJ. Inhibition of glycogen synthase kinase-3beta improves tolerance to ischemia in hypertrophied hearts. Ann Thorac Surg. 2007 Jul; 84(1):126-33. PMID: 17588398; PMCID: PMC3444259.
    Citations: 10     Fields:    Translation:AnimalsCells
  34. Hofstaetter JG, Saad FA, Sunk IG, Bobacz K, Friehs I, Glimcher MJ. Age-dependent expression of VEGF isoforms and receptors in the rabbit anterior cruciate ligament. Biochim Biophys Acta. 2007 Jul; 1770(7):997-1002. PMID: 17459591.
    Citations: 5     Fields:    Translation:Animals
  35. Roy N, Friehs I, Cowan DB, Zurakowski D, McGowan FX, del Nido PJ. Dopamine induces postischemic cardiomyocyte apoptosis in vivo: an effect ameliorated by propofol. Ann Thorac Surg. 2006 Dec; 82(6):2192-9. PMID: 17126134.
    Citations: 7     Fields:    Translation:AnimalsCells
  36. Friehs I, Barillas R, Vasilyev NV, Roy N, McGowan FX, del Nido PJ. Vascular endothelial growth factor prevents apoptosis and preserves contractile function in hypertrophied infant heart. Circulation. 2006 Jul 04; 114(1 Suppl):I290-5. PMID: 16820588; PMCID: PMC3444258.
    Citations: 36     Fields:    Translation:AnimalsCells
  37. Choi YH, Stamm C, Hammer PE, Kwaku KF, Marler JJ, Friehs I, Jones M, Rader CM, Roy N, Eddy MT, Triedman JK, Walsh EP, McGowan FX, del Nido PJ, Cowan DB. Cardiac conduction through engineered tissue. Am J Pathol. 2006 Jul; 169(1):72-85. PMID: 16816362; PMCID: PMC1534117.
    Citations: 27     Fields:    Translation:AnimalsCells
  38. Friehs I, Margossian RE, Moran AM, Cao-Danh H, Moses MA, del Nido PJ. Vascular endothelial growth factor delays onset of failure in pressure-overload hypertrophy through matrix metalloproteinase activation and angiogenesis. Basic Res Cardiol. 2006 May; 101(3):204-13. PMID: 16369727; PMCID: PMC3444246.
    Citations: 34     Fields:    Translation:AnimalsCells
  39. Friehs I, Cao-Danh H, Nathan M, McGowan FX, del Nido PJ. Impaired insulin-signaling in hypertrophied hearts contributes to ischemic injury. Biochem Biophys Res Commun. 2005 May 27; 331(1):15-22. PMID: 15845351; PMCID: PMC3444251.
    Citations: 8     Fields:    Translation:AnimalsCells
  40. Nathan M, Friehs I, Choi YH, Cowan DB, Cao-Danh H, McGowan FX, del Nido PJ. Cyclosporin A but not FK-506 protects against dopamine-induced apoptosis in the stunned heart. Ann Thorac Surg. 2005 May; 79(5):1620-6. PMID: 15854943.
    Citations: 5     Fields:    Translation:Animals
  41. Friehs I, Moran AM, Stamm C, Choi YH, Cowan DB, McGowan FX, del Nido PJ. Promoting angiogenesis protects severely hypertrophied hearts from ischemic injury. Ann Thorac Surg. 2004 Jun; 77(6):2004-10; discussion 2011. PMID: 15172254.
    Citations: 25     Fields:    Translation:Animals
  42. Stamm C, Friehs I, Choi YH, Zurakowski D, McGowan FX, del Nido PJ. Cytosolic calcium in the ischemic rabbit heart: assessment by pH- and temperature-adjusted rhod-2 spectrofluorometry. Cardiovasc Res. 2003 Sep 01; 59(3):695-704. PMID: 14499871.
    Citations: 13     Fields:    Translation:AnimalsCells
  43. Friehs I, Cao-Danh H, Stamm C, Cowan DB, McGowan FX, del Nido PJ. Postnatal increase in insulin-sensitive glucose transporter expression is associated with improved recovery of postischemic myocardial function. J Thorac Cardiovasc Surg. 2003 Jul; 126(1):263-71. PMID: 12878964.
    Citations: 4     Fields:    Translation:Animals
  44. Moran AM, Friehs I, Takeuchi K, Stamm C, Hammer PE, McGowan FX, del Nido PJ, Colan SD. Noninvasive serial evaluation of myocardial mechanics in pressure overload hypertrophy of rabbit myocardium. Herz. 2003 Feb; 28(1):52-62. PMID: 12616321.
    Citations: 11     Fields:    Translation:Animals
  45. Friehs I, del Nido PJ. Increased susceptibility of hypertrophied hearts to ischemic injury. Ann Thorac Surg. 2003 Feb; 75(2):S678-84. PMID: 12607712.
    Citations: 18     Fields:    Translation:AnimalsCells
  46. Stamm C, Friehs I, Duebener LF, Zurakowski D, Mayer JE, Jonas RA, del Nido PJ. Improving results of the modified Fontan operation in patients with heterotaxy syndrome. Ann Thorac Surg. 2002 Dec; 74(6):1967-77; discussion 1978. PMID: 12643382.
    Citations: 16     Fields:    Translation:Humans
  47. Stamm C, Friehs I, Cowan DB, Cao-Danh H, Choi YH, Duebener LF, McGowan FX, del Nido PJ. Dopamine treatment of postischemic contractile dysfunction rapidly induces calcium-dependent pro-apoptotic signaling. Circulation. 2002 Sep 24; 106(12 Suppl 1):I290-8. PMID: 12354748.
    Citations: 12     Fields:    Translation:AnimalsCells
  48. Munakata M, Stamm C, Friehs I, Zurakowski D, Cowan DB, Cao-Danh H, McGowan FX, del Nido PJ. Protective effects of protein kinase C during myocardial ischemia require activation of phosphatidyl-inositol specific phospholipase C. Ann Thorac Surg. 2002 Apr; 73(4):1236-45. PMID: 11998814.
    Citations: 4     Fields:    Translation:AnimalsCells
  49. Stamm C, Friehs I, Zurakowski D, Scheule AM, Moran AM, Lock JE, Mayer JE, del Nido PJ, Jonas RA. Outcome after reconstruction of discontinuous pulmonary arteries. J Thorac Cardiovasc Surg. 2002 Feb; 123(2):246-57. PMID: 11828283.
    Citations: 8     Fields:    Translation:Humans
  50. Stamm C, Cowan DB, Friehs I, Noria S, del Nido PJ, McGowan FX. Rapid endotoxin-induced alterations in myocardial calcium handling: obligatory role of cardiac TNF-alpha. Anesthesiology. 2001 Dec; 95(6):1396-405. PMID: 11748398.
    Citations: 13     Fields:    Translation:AnimalsCells
  51. Friehs I, Stamm C, Cao-Danh H, McGowan FX, del Nido PJ. Insulin-like growth factor-1 improves postischemic recovery in hypertrophied hearts. Ann Thorac Surg. 2001 Nov; 72(5):1650-6. PMID: 11722060.
    Citations: 7     Fields:    Translation:Animals
  52. Stamm C, Friehs I, Cowan DB, Moran AM, Cao-Danh H, Duebener LF, del Nido PJ, McGowan FX. Inhibition of tumor necrosis factor-alpha improves postischemic recovery of hypertrophied hearts. Circulation. 2001 Sep 18; 104(12 Suppl 1):I350-5. PMID: 11568081.
    Citations: 23     Fields:    Translation:AnimalsCells
  53. Stamm C, Friehs I, Cowan DB, Cao-Danh H, Noria S, Munakata M, McGowan FX, del Nido PJ. Post-ischemic PKC inhibition impairs myocardial calcium handling and increases contractile protein calcium sensitivity. Cardiovasc Res. 2001 Jul; 51(1):108-21. PMID: 11399253.
    Citations: 6     Fields:    Translation:Animals
  54. Stamm C, Friehs I, Ho SY, Moran AM, Jonas RA, del Nido PJ. Congenital supravalvar aortic stenosis: a simple lesion? Eur J Cardiothorac Surg. 2001 Feb; 19(2):195-202. PMID: 11167112.
    Citations: 23     Fields:    Translation:Humans
  55. Stamm C, Friehs I, Mayer JE, Zurakowski D, Triedman JK, Moran AM, Walsh EP, Lock JE, Jonas RA. Long-term results of the lateral tunnel Fontan operation. J Thorac Cardiovasc Surg. 2001 Jan; 121(1):28-41. PMID: 11135157.
    Citations: 38     Fields:    Translation:Humans
  56. Toyoda Y, Friehs I, Parker RA, Levitsky S, McCully JD. Differential role of sarcolemmal and mitochondrial K(ATP) channels in adenosine-enhanced ischemic preconditioning. Am J Physiol Heart Circ Physiol. 2000 Dec; 279(6):H2694-703. PMID: 11087223.
    Citations: 14     Fields:    Translation:AnimalsCells
  57. Stamm C, Friehs I, Moran AM, Zurakowski D, Bacha E, Mayer JE, Jonas RA, Del Nido PJ. Surgery for bilateral outflow tract obstruction in elastin arteriopathy. J Thorac Cardiovasc Surg. 2000 Oct; 120(4):755-63. PMID: 11003759.
    Citations: 5     Fields:    Translation:Humans
  58. Friehs I, Moran AM, Stamm C, Colan SD, Takeuchi K, Cao-Danh H, Rader CM, McGowan FX, del Nido PJ. Impaired glucose transporter activity in pressure-overload hypertrophy is an early indicator of progression to failure. Circulation. 1999 Nov 09; 100(19 Suppl):II187-93. PMID: 10567302.
    Citations: 18     Fields:    Translation:Animals
  59. Stamm C, Kreutzer C, Zurakowski D, Nollert G, Friehs I, Mayer JE, Jonas RA, del Nido PJ. Forty-one years of surgical experience with congenital supravalvular aortic stenosis. J Thorac Cardiovasc Surg. 1999 Nov; 118(5):874-85. PMID: 10534693.
    Citations: 16     Fields:    Translation:Humans
  60. Lardo AC, Webber SA, Iyengar A, del Nido PJ, Friehs I, Cape EG. Bidirectional superior cavopulmonary anastomosis improves mechanical efficiency in dilated atriopulmonary connections. J Thorac Cardiovasc Surg. 1999 Oct; 118(4):681-91. PMID: 10504635.
    Citations: 3     Fields:    Translation:Animals
  61. Lardo AC, Webber SA, Friehs I, del Nido PJ, Cape EG. Fluid dynamic comparison of intra-atrial and extracardiac total cavopulmonary connections. J Thorac Cardiovasc Surg. 1999 Apr; 117(4):697-704. PMID: 10096964.
    Citations: 24     Fields:    Translation:Animals
  62. Takeuchi K, del Nido PJ, Ibrahim AE, Cao-Danh H, Friehs I, Glynn P, Poutias D, Cowan DB, McGowan FX. Vesnarinone and amrinone reduce the systemic inflammatory response syndrome. J Thorac Cardiovasc Surg. 1999 Feb; 117(2):375-82. PMID: 9918980.
    Citations: 3     Fields:    Translation:AnimalsCells
  63. Takeuchi K, Cao-Danh H, Friehs I, Glynn P, D'Agostino D, Simplaceanu E, McGowan FX, del Nido PJ. Administration of fructose 1,6-diphosphate during early reperfusion significantly improves recovery of contractile function in the postischemic heart. J Thorac Cardiovasc Surg. 1998 Aug; 116(2):335-43. PMID: 9699588.
    Citations: 12     Fields:    Translation:Animals
  64. Urlesberger B, Zobel G, Rödl S, Dacar D, Friehs I, Leschnik B, Muntean W. Activation of the clotting system: heparin-coated versus non coated systems for extracorporeal circulation. Int J Artif Organs. 1997 Dec; 20(12):708-12. PMID: 9506788.
    Citations: 4     Fields:    Translation:Animals
  65. Friehs I, Cao-Danh H, Takahashi S, Buenaventura P, Glynn P, McGowan FX, del Nido PJ. Adenosine prevents protein kinase C activation during hypothermic ischemia. Circulation. 1997 Nov 04; 96(9 Suppl):II-221-5; discussion II-225-6. PMID: 9386102.
    Citations: 2     Fields:    Translation:AnimalsCells
  66. Shum-Tim D, Duncan BW, Hraska V, Friehs I, Shin'oka T, Jonas RA. Evaluation of a pulsatile pediatric ventricular assist device in an acute right heart failure model. Ann Thorac Surg. 1997 Nov; 64(5):1374-80. PMID: 9386707.
    Citations: 4     Fields:    Translation:HumansAnimals
  67. Lardo AC, del Nido PJ, Webber SA, Friehs I, Cape EG. Hemodynamic effect of progressive right atrial dilatation in atriopulmonary connections. J Thorac Cardiovasc Surg. 1997 Jul; 114(1):2-8. PMID: 9240287.
    Citations: 4     Fields:    Translation:Animals
  68. Maechler HE, Lueger A, Bergmann P, Friehs I, Stark G, Berger J, Anelli-Monti M, Rehak P, Rigler B. A high-resolution esophageal electrocardiogram for monitoring atrial activity in the hypothermic potassium-arrested heart. Anesth Analg. 1997 Mar; 84(3):484-90. PMID: 9052287.
    Citations:    Fields:    Translation:Humans
  69. Zobel G, Urlesberger B, Dacar D, Rödl S, Reiterer F, Friehs I. Partial liquid ventilation combined with inhaled nitric oxide in acute respiratory failure with pulmonary hypertension in piglets. Pediatr Res. 1997 Feb; 41(2):172-7. PMID: 9029634.
    Citations: 1     Fields:    Translation:HumansAnimals
  70. Zobel G, Dacar D, Rödl S, Friehs I. Inhaled nitric oxide versus inhaled prostacyclin and intravenous versus inhaled prostacyclin in acute respiratory failure with pulmonary hypertension in piglets. Pediatr Res. 1995 Aug; 38(2):198-204. PMID: 7478816.
    Citations: 6     Fields:    Translation:Animals
  71. Friehs I, Dacar D, Gamillscheg A, Mächler H, Anelli-Monti M, Oberwalder P, Beitzke A, Metzler H, Rigler B. [Total cavo-pulmonary connection as a therapeutic principle in anatomical and functional univentricular heart]. Wien Klin Wochenschr. 1995; 107(23):714-7. PMID: 8560892.
    Citations: 1     Fields:    Translation:Humans
  72. Zobel G, Kuttnig-Haim M, Decar D, Urlesberger B, Riccabona M, Reiterer F, Maurer U, Friehs I, Berger J, Trop M, et al. [Extracorporeal membrane oxygenation in newborn infants and children]. Wien Klin Wochenschr. 1995; 107(14):427-35. PMID: 7668003.
    Citations:    Fields:    Translation:Humans
  73. Rabl H, Friehs I, Gutschi S, Pascher O, Koch G. Diagnosis and treatment of carotid body tumors. Thorac Cardiovasc Surg. 1993 Dec; 41(6):340-3. PMID: 8128461.
    Citations: 4     Fields:    Translation:Humans
  74. Friehs I, Friehs GM, Friehs GB. Air embolism with bilateral pneumothorax after a five-meter dive. Undersea Hyperb Med. 1993 Jun; 20(2):155-7. PMID: 8329942.
    Citations: 2     Fields:    Translation:Humans
  75. Friehs I, Eber B, Friehs G, Langsteger W, Koch G. IgG-anticardiolipin-antibodies are markers for cerebral and peripheral artery disease. Vasa. 1992; 21(2):158-62. PMID: 1621434.
    Citations: 1     Fields:    Translation:HumansCTClinical Trials
  76. Rabl H, Friehs I, Pascher O, Gutschi S, Koch G. [Carotid glomus tumors: vascular surgery from the oncologic viewpoint]. Vasa Suppl. 1992; 37:73-4. PMID: 1481109.
    Citations:    Fields:    Translation:HumansCells
  77. Friehs I, Koch G. Congenital giant arteriovenous malformation in a 31-year-old male. Thorac Cardiovasc Surg. 1991 Apr; 39(2):110-2. PMID: 1877051.
    Citations: 2     Fields:    Translation:Humans
  78. Schaffer-Kronberger E, Eber B, Wawschinek O, Dusleag J, Friehs I, Gogg R, Petek W, Klein W. Serum selenium levels in distinct manifestations of coronary artery disease. Acta Med Austriaca. 1990; 17(1):22-4. PMID: 2353564.
    Citations:    Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.