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Mustafa Sahin, Ph.D., M.D.

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Biography
1988
Award for Best Thesis in Biochemistry
1988
Magna Cum Laude
1988
Sigma Xi Honorary Society
1995
Alpha Omega Alpha Honor Medical Society
1995
M.D./Ph.D. Thesis Award
2000
Outstanding Junior Member Award
2005
Young Investigator Award
2005
Young Investigator Award in SMA
2009
John Merck Scholar Award

Overview

Mentoring
Activation Dependent Modulation of the Neuronal Circadian Clock
Summer, 05/24/10 - 08/31/10
Diffusion Tensor Tractography Reveals Impaired Language Pathways in Tuberous Sclerosis Complex Patients with Autism
Summer, 06/20/11 - 08/12/11

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R13HD102087 (SAHIN, MUSTAFA) Mar 15, 2020 - Feb 28, 2021
    NIH/NICHD
    2020 Fragile X and Autism Related Disorders GRS/GRC
    Role: Principal Investigator
  2. R01NS113591 (SAHIN, MUSTAFA) Aug 1, 2019 - May 31, 2023
    NIH/NINDS
    Disrupted ciliary signaling in the brain pathology of Tuberous Sclerosis Complex
    Role: Principal Investigator
  3. T32MH112510 (NELSON, CHARLES ALEXANDER) Jul 1, 2017 - Jun 30, 2022
    NIH/NIMH
    Translational Post-doctoral Training in Neurodevelopment
    Role: Co-Principal Investigator
  4. U54HD090255 (POMEROY, SCOTT LOREN) Sep 23, 2016 - May 31, 2021
    NIH/NICHD
    Boston Intellectual and Developmental Disabilities Research Center
    Role: Co-Principal Investigator
  5. U54NS092090 (SAHIN, MUSTAFA) Sep 20, 2014 - Jul 31, 2024
    NIH/NINDS
    Developmental Synaptopathies Associated with TSC, PTEN and SHANK3 Mutations
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Giannikou K, Zhu Z, Kim J, Winden KD, Tyburczy ME, Marron D, Parker JS, Hebert Z, Bongaarts A, Taing L, Long HW, Pisano WV, Alexandrescu S, Godlewski B, Nellist M, Kotulska K, Jozwiak S, Roszkowski M, Mandera M, Thiele EA, Lidov H, Getz G, Devinsky O, Lawrence MS, Ligon KL, Ellison DW, Sahin M, Aronica E, Meredith DM, Kwiatkowski DJ. Subependymal giant cell astrocytomas are characterized by mTORC1 hyperactivation, a very low somatic mutation rate, and a unique gene expression profile. Mod Pathol. 2020 Oct 13. PMID: 33051600.
    Citations:    
  2. Srivastava S, Love-Nichols JA, Dies KA, Ledbetter DH, Martin CL, Chung WK, Firth HV, Frazier T, Hansen RL, Prock L, Brunner H, Hoang N, Scherer SW, Sahin M, Miller DT. Correction: Meta-analysis and multidisciplinary consensus statement: exome sequencing is a first-tier clinical diagnostic test for individuals with neurodevelopmental disorders. Genet Med. 2020 Oct; 22(10):1731-1732. PMID: 32728138.
    Citations:    
  3. Ebrahimi-Fakhari D, Teinert J, Behne R, Wimmer M, D'Amore A, Eberhardt K, Brechmann B, Ziegler M, Jensen DM, Nagabhyrava P, Geisel G, Carmody E, Shamshad U, Dies KA, Yuskaitis CJ, Salussolia CL, Ebrahimi-Fakhari D, Pearson TS, Saffari A, Ziegler A, Kölker S, Volkmann J, Wiesener A, Bearden DR, Lakhani S, Segal D, Udwadia-Hegde A, Martinuzzi A, Hirst J, Perlman S, Takiyama Y, Xiromerisiou G, Vill K, Walker WO, Shukla A, Dubey Gupta R, Dahl N, Aksoy A, Verhelst H, Delgado MR, Kremlikova Pourova R, Sadek AA, Elkhateeb NM, Blumkin L, Brea-Fernández AJ, Dacruz-Álvarez D, Smol T, Ghoumid J, Miguel D, Heine C, Schlump JU, Langen H, Baets J, Bulk S, Darvish H, Bakhtiari S, Kruer MC, Lim-Melia E, Aydinli N, Alanay Y, El-Rashidy O, Nampoothiri S, Patel C, Beetz C, Bauer P, Yoon G, Guillot M, Miller SP, Bourinaris T, Houlden H, Robelin L, Anheim M, Alamri AS, Mahmoud AAH, Inaloo S, Habibzadeh P, Faghihi MA, Jansen AC, Brock S, Roubertie A, Darras BT, Agrawal PB, Santorelli FM, Gleeson J, Zaki MS, Sheikh SI, Bennett JT, Sahin M. Defining the clinical, molecular and imaging spectrum of adaptor protein complex 4-associated hereditary spastic paraplegia. Brain. 2020 Oct 01; 143(10):2929-2944. PMID: 32979048.
    Citations:    
  4. Sahin M, Akkus E. Comment on "Potential Role of ACE2 in Coronavirus Disease 2019 (COVID-19) Prevention and Management". J Transl Int Med. 2020 Sep; 8(3):199. PMID: 33062597.
    Citations:    
  5. Constantino JN, Sahin M, Piven J, Rodgers R, Tschida J. The Impact of COVID-19 on Individuals With Intellectual and Developmental Disabilities: Clinical and Scientific Priorities. Am J Psychiatry. 2020 Aug 28; appiajp202020060780. PMID: 32854530.
    Citations:    
  6. Farach LS, Richard MA, Lupo PJ, Sahin M, Krueger DA, Wu JY, Bebin EM, Au KS, Northrup H. Epilepsy Risk Prediction Model for Patients With Tuberous Sclerosis Complex. Pediatr Neurol. 2020 Jul 29; 113:46-50. PMID: 33011641.
    Citations:    
  7. Di Nardo A, Lenoël I, Winden KD, Rühmkorf A, Modi ME, Barrett L, Ercan-Herbst E, Venugopal P, Behne R, Lopes CAM, Kleiman RJ, Bettencourt-Dias M, Sahin M. Phenotypic Screen with TSC-Deficient Neurons Reveals Heat-Shock Machinery as a Druggable Pathway for mTORC1 and Reduced Cilia. Cell Rep. 2020 Jun 23; 31(12):107780. PMID: 32579942.
    Citations:    
  8. Karimi D, Peters JM, Ouaalam A, Prabhu SP, Sahin M, Krueger DA, Kolevzon A, Eng C, Warfield SK, Gholipour A. LEARNING TO DETECT BRAIN LESIONS FROM NOISY ANNOTATIONS. Proc IEEE Int Symp Biomed Imaging. 2020 Apr; 2020:1910-1914. PMID: 32879655.
    Citations:    
  9. Gergoudis K, Weinberg A, Templin J, Farmer C, Durkin A, Weissman J, Siper P, Foss-Feig J, Del Pilar Trelles M, Bernstein JA, Buxbaum JD, Berry-Kravis E, Powell CM, Sahin M, Soorya L, Thurm A, Kolevzon A. Psychometric Study of the Social Responsiveness Scale in Phelan-McDermid Syndrome. Autism Res. 2020 Aug; 13(8):1383-1396. PMID: 32406614.
    Citations:    
  10. Gonçalves IDCG, Brecht J, Thelen MP, Rehorst WA, Peters M, Lee HJ, Motameny S, Torres-Benito L, Ebrahimi-Fakhari D, Kononenko NL, Altmüller J, Vilchez D, Sahin M, Wirth B, Kye MJ. Author Correction: Neuronal activity regulates DROSHA via autophagy in spinal muscular atrophy. Sci Rep. 2020 May 13; 10(1):8206. PMID: 32398663.
    Citations:    
  11. Modi ME, Sahin M. Tau: A Novel Entry Point for mTOR-Based Treatments in Autism Spectrum Disorder? Neuron. 2020 05 06; 106(3):359-361. PMID: 32380047.
    Citations:    
  12. Sánchez Fernández I, Yang E, Calvachi P, Amengual-Gual M, Wu JY, Krueger D, Northrup H, Bebin ME, Sahin M, Yu KH, Peters JM. Deep learning in rare disease. Detection of tubers in tuberous sclerosis complex. PLoS One. 2020; 15(4):e0232376. PMID: 32348367.
    Citations:    
  13. Grayson LE, Peters JM, McPherson T, Krueger DA, Sahin M, Wu JY, Northrup HA, Porter B, Cutter GR, O'Kelley SE, Krefting J, Stone SS, Madsen JR, Fallah A, Blount JP, Weiner HL, Bebin EM. Pilot Study of Neurodevelopmental Impact of Early Epilepsy Surgery in Tuberous Sclerosis Complex. Pediatr Neurol. 2020 08; 109:39-46. PMID: 32418847.
    Citations:    
  14. Scherrer B, Prohl AK, Taquet M, Kapur K, Peters JM, Tomas-Fernandez X, Davis PE, M Bebin E, Krueger DA, Northrup H, Y Wu J, Sahin M, Warfield SK. The Connectivity Fingerprint of the Fusiform Gyrus Captures the Risk of Developing Autism in Infants with Tuberous Sclerosis Complex. Cereb Cortex. 2020 Apr 14; 30(4):2199-2214. PMID: 31812987.
    Citations:    
  15. O'Brien AM, Bayet L, Riley K, Nelson CA, Sahin M, Modi ME. Auditory Processing of Speech and Tones in Children With Tuberous Sclerosis Complex. Front Integr Neurosci. 2020; 14:14. PMID: 32327979.
    Citations:    
  16. Uysal SP, Sahin M. Tuberous Sclerosis Complex: A review of the past, present and future. Turk J Med Sci. 2020 03 28. PMID: 32222129.
    Citations:    
  17. D'Amore A, Tessa A, Naef V, Bassi MT, Citterio A, Romaniello R, Fichi G, Galatolo D, Mero S, Battini R, Bertocci G, Baldacci J, Sicca F, Gemignani F, Ricca I, Rubegni A, Hirst J, Marchese M, Sahin M, Ebrahimi-Fakhari D, Santorelli FM. Loss of ap4s1 in zebrafish leads to neurodevelopmental defects resembling spastic paraplegia 52. Ann Clin Transl Neurol. 2020 04; 7(4):584-589. PMID: 32216065.
    Citations:    
  18. Gökçay Canpolat A, Sahin M. Glucose Lowering Treatment Modalities of Type 2 Diabetes Mellitus. Adv Exp Med Biol. 2020 Mar 22. PMID: 32200500.
    Citations:    
  19. Cook IA, Wilson AC, Peters JM, Goyal MN, Bebin EM, Northrup H, Krueger D, Leuchter AF, Sahin M. EEG Spectral Features in Sleep of Autism Spectrum Disorders in Children with Tuberous Sclerosis Complex. J Autism Dev Disord. 2020 Mar; 50(3):916-923. PMID: 31811616.
    Citations:    
  20. Kodani A, Kenny C, Lai A, Gonzalez DM, Stronge E, Sejourne GM, Isacco L, Partlow JN, O'Donnell A, McWalter K, Byrne AB, Barkovich AJ, Yang E, Hill RS, Gawlinski P, Wiszniewski W, Cohen JS, Fatemi SA, Baranano KW, Sahin M, Vossler DG, Yuskaitis CJ, Walsh CA. Posterior Neocortex-Specific Regulation of Neuronal Migration by CEP85L Identifies Maternal Centriole-Dependent Activation of CDK5. Neuron. 2020 04 22; 106(2):246-255.e6. PMID: 32097629.
    Citations:    
  21. Afshar Saber W, Sahin M. Recent advances in human stem cell-based modeling of Tuberous Sclerosis Complex. Mol Autism. 2020 02 19; 11(1):16. PMID: 32075691.
    Citations:    
  22. Uçan B, Sahin M, Özbek M, Kizilgül M, Sayki Arslan M, Çaliskan M, Saylam G, Çakal E. Lobectomy may not be suitable for patients with follicular neoplasm cytology Turk J Med Sci. 2020 02 13; 50(1):8-11. PMID: 31340635.
    Citations:    
  23. Bassell J, Srivastava S, Prohl AK, Scherrer B, Kapur K, Filip-Dhima R, Berry-Kravis E, Soorya L, Thurm A, Powell CM, Bernstein JA, Buxbaum JD, Kolevzon A, Warfield SK, Sahin M. Diffusion Tensor Imaging Abnormalities in the Uncinate Fasciculus and Inferior Longitudinal Fasciculus in Phelan-McDermid Syndrome. Pediatr Neurol. 2020 05; 106:24-31. PMID: 32107139.
    Citations:    
  24. Behne R, Teinert J, Wimmer M, D'Amore A, Davies AK, Scarrott JM, Eberhardt K, Brechmann B, Chen IP, Buttermore ED, Barrett L, Dwyer S, Chen T, Hirst J, Wiesener A, Segal D, Martinuzzi A, Duarte ST, Bennett JT, Bourinaris T, Houlden H, Roubertie A, Santorelli FM, Robinson M, Azzouz M, Lipton JO, Borner GHH, Sahin M, Ebrahimi-Fakhari D. Adaptor protein complex 4 deficiency: a paradigm of childhood-onset hereditary spastic paraplegia caused by defective protein trafficking. Hum Mol Genet. 2020 01 15; 29(2):320-334. PMID: 31915823.
    Citations:    
  25. Sundberg M, Sahin M. Modeling Neurodevelopmental Deficits in Tuberous Sclerosis Complex with Stem Cell Derived Neural Precursors and Neurons. Adv Neurobiol. 2020; 25:1-31. PMID: 32578142.
    Citations:    
  26. Peters JM, Hyde DE, Chu CJ, Boom M, Scherrer B, Madsen JR, Stone SS, Ouaalam H, Prabhu SP, Sahin M, Warfield SK. Lesion-Constrained Electrical Source Imaging: A Novel Approach in Epilepsy Surgery for Tuberous Sclerosis Complex. J Clin Neurophysiol. 2020 Jan; 37(1):79-86. PMID: 31261349.
    Citations:    
  27. Schoenberger A, Capal JK, Ondracek A, Horn PS, Murray D, Byars AW, Pearson DA, Williams ME, Bebin M, Northrup H, Wu JY, Sahin M, Krueger DA. Language predictors of autism spectrum disorder in young children with tuberous sclerosis complex. Epilepsy Behav. 2020 02; 103(Pt A):106844. PMID: 31864941.
    Citations:    
  28. Prohl AK, Scherrer B, Tomas-Fernandez X, Davis PE, Filip-Dhima R, Prabhu SP, Peters JM, Bebin EM, Krueger DA, Northrup H, Wu JY, Sahin M, Warfield SK. Early white matter development is abnormal in tuberous sclerosis complex patients who develop autism spectrum disorder. J Neurodev Disord. 2019 12 16; 11(1):36. PMID: 31838998.
    Citations:    
  29. Wu JY, Goyal M, Peters JM, Krueger D, Sahin M, Northrup H, Au KS, O'Kelley S, Williams M, Pearson DA, Hanson E, Byars AW, Krefting J, Beasley M, Cutter G, Limdi N, Bebin EM. Scalp EEG spikes predict impending epilepsy in TSC infants: A longitudinal observational study. Epilepsia. 2019 12; 60(12):2428-2436. PMID: 31691264.
    Citations:    
  30. Busch RM, Srivastava S, Hogue O, Frazier TW, Klaas P, Hardan A, Martinez-Agosto JA, Sahin M, Eng C. Neurobehavioral phenotype of autism spectrum disorder associated with germline heterozygous mutations in PTEN. Transl Psychiatry. 2019 10 08; 9(1):253. PMID: 31594918.
    Citations:    
  31. Winden KD, Sundberg M, Yang C, Wafa SMA, Dwyer S, Chen PF, Buttermore ED, Sahin M. Biallelic Mutations in TSC2 Lead to Abnormalities Associated with Cortical Tubers in Human iPSC-Derived Neurons. J Neurosci. 2019 11 20; 39(47):9294-9305. PMID: 31591157.
    Citations:    
  32. Sanders SJ, Sahin M, Hostyk J, Thurm A, Jacquemont S, Avillach P, Douard E, Martin CL, Modi ME, Moreno-De-Luca A, Raznahan A, Anticevic A, Dolmetsch R, Feng G, Geschwind DH, Glahn DC, Goldstein DB, Ledbetter DH, Mulle JG, Pasca SP, Samaco R, Sebat J, Pariser A, Lehner T, Gur RE, Bearden CE. A framework for the investigation of rare genetic disorders in neuropsychiatry. Nat Med. 2019 10; 25(10):1477-1487. PMID: 31548702.
    Citations:    
  33. Teinert J, Behne R, D'Amore A, Wimmer M, Dwyer S, Chen T, Buttermore ED, Chen IP, Sahin M, Ebrahimi-Fakhari D. Generation and characterization of six human induced pluripotent stem cell lines (iPSC) from three families with AP4B1-associated hereditary spastic paraplegia (SPG47). Stem Cell Res. 2019 10; 40:101575. PMID: 31525725.
    Citations:    
  34. Yuskaitis CJ, Rossitto LA, Gurnani S, Bainbridge E, Poduri A, Sahin M. Chronic mTORC1 inhibition rescues behavioral and biochemical deficits resulting from neuronal Depdc5 loss in mice. Hum Mol Genet. 2019 09 01; 28(17):2952-2964. PMID: 31174205.
    Citations:    
  35. Dickinson A, Varcin KJ, Sahin M, Nelson CA, Jeste SS. Early patterns of functional brain development associated with autism spectrum disorder in tuberous sclerosis complex. Autism Res. 2019 12; 12(12):1758-1773. PMID: 31419043.
    Citations:    
  36. Dikker O, Çetin Dag N, Sahin M, Türkkan E, Dag H. The association of angiopoietin-like peptide 4 levels with obesity and hepatosteatosis in adolescents. Cytokine. 2020 01; 125:154802. PMID: 31419758.
    Citations:    
  37. Prohl AK, Scherrer B, Tomas-Fernandez X, Filip-Dhima R, Kapur K, Velasco-Annis C, Clancy S, Carmody E, Dean M, Valle M, Prabhu SP, Peters JM, Bebin EM, Krueger DA, Northrup H, Wu JY, Sahin M, Warfield SK. Reproducibility of Structural and Diffusion Tensor Imaging in the TACERN Multi-Center Study. Front Integr Neurosci. 2019; 13:24. PMID: 31417372.
    Citations:    
  38. Ahtam B, Dehaes M, Sliva DD, Peters JM, Krueger DA, Bebin EM, Northrup H, Wu JY, Warfield SK, Sahin M, Grant PE. Resting-State fMRI Networks in Children with Tuberous Sclerosis Complex. J Neuroimaging. 2019 11; 29(6):750-759. PMID: 31304656.
    Citations:    
  39. Davis PE, Kapur K, Filip-Dhima R, Trowbridge SK, Little E, Wilson A, Leuchter A, Bebin EM, Krueger D, Northrup H, Wu JY, Sahin M, Peters JM. Increased electroencephalography connectivity precedes epileptic spasm onset in infants with tuberous sclerosis complex. Epilepsia. 2019 08; 60(8):1721-1732. PMID: 31297797.
    Citations:    
  40. de Groen AC, Bolton J, Bergin AM, Sahin M, Peters JM. The Evolution of Subclinical Seizures in Children With Tuberous Sclerosis Complex. J Child Neurol. 2019 10; 34(12):770-777. PMID: 31290714.
    Citations:    
  41. Peters JM, Struyven RR, Prohl AK, Vasung L, Stajduhar A, Taquet M, Bushman JJ, Lidov H, Singh JM, Scherrer B, Madsen JR, Prabhu SP, Sahin M, Afacan O, Warfield SK. White matter mean diffusivity correlates with myelination in tuberous sclerosis complex. Ann Clin Transl Neurol. 2019 07; 6(7):1178-1190. PMID: 31353853.
    Citations:    
  42. Srivastava S, Love-Nichols JA, Dies KA, Ledbetter DH, Martin CL, Chung WK, Firth HV, Frazier T, Hansen RL, Prock L, Brunner H, Hoang N, Scherer SW, Sahin M, Miller DT. Meta-analysis and multidisciplinary consensus statement: exome sequencing is a first-tier clinical diagnostic test for individuals with neurodevelopmental disorders. Genet Med. 2019 11; 21(11):2413-2421. PMID: 31182824.
    Citations:    
  43. Giannikou K, Lasseter KD, Grevelink JM, Tyburczy ME, Dies KA, Zhu Z, Hamieh L, Wollison BM, Thorner AR, Ruoss SJ, Thiele EA, Sahin M, Kwiatkowski DJ. Low-level mosaicism in tuberous sclerosis complex: prevalence, clinical features, and risk of disease transmission. Genet Med. 2019 11; 21(11):2639-2643. PMID: 31160751.
    Citations:    
  44. Salussolia CL, Klonowska K, Kwiatkowski DJ, Sahin M. Genetic Etiologies, Diagnosis, and Treatment of Tuberous Sclerosis Complex. Annu Rev Genomics Hum Genet. 2019 08 31; 20:217-240. PMID: 31018109.
    Citations:    
  45. Williams ME, Pearson DA, Capal JK, Byars AW, Murray DS, Kissinger R, O'Kelley SE, Hanson E, Bing NM, Kent B, Wu JY, Northrup H, Bebin EM, Sahin M, Krueger D. Impacting development in infants with tuberous sclerosis complex: Multidisciplinary research collaboration. Am Psychol. 2019 04; 74(3):356-367. PMID: 30945897.
    Citations:    
  46. Farach LS, Pearson DA, Woodhouse JP, Schraw JM, Sahin M, Krueger DA, Wu JY, Bebin EM, Lupo PJ, Au KS, Northrup H. Tuberous Sclerosis Complex Genotypes and Developmental Phenotype. Pediatr Neurol. 2019 07; 96:58-63. PMID: 31005478.
    Citations:    
  47. Keskin C, Sahin M, Hasanov R, Aydogan BI, Demir O, Emral R, Gullu S, Erdogan MF, Gedik V, Uysal AR, Baskal N, Corapcioglu D. Frequency of thyroid nodules and thyroid cancer in thyroidectomized patients with Graves' disease. Arch Med Sci. 2020; 16(2):302-307. PMID: 32190140.
    Citations:    
  48. Sahin M, Jones SR, Sweeney JA, Berry-Kravis E, Connors BW, Ewen JB, Hartman AL, Levin AR, Potter WZ, Mamounas LA. Discovering translational biomarkers in neurodevelopmental disorders. Nat Rev Drug Discov. 2018 Dec 20. PMID: 30936503.
    Citations:    
  49. Marami B, Scherrer B, Khan S, Afacan O, Prabhu SP, Sahin M, Warfield SK, Gholipour A. Motion-robust diffusion compartment imaging using simultaneous multi-slice acquisition. Magn Reson Med. 2019 05; 81(5):3314-3329. PMID: 30443929.
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  50. Purtell H, Dhamne SC, Gurnani S, Bainbridge E, Modi ME, Lammers SHT, Super CE, Hameed MQ, Johnson EL, Sahin M, Rotenberg A. Electrographic spikes are common in wildtype mice. Epilepsy Behav. 2018 12; 89:94-98. PMID: 30399547.
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  51. Jülich K, Neuberger I, Sahin M, Takeoka M, Pinto A, Prabhu SP. Yield of Emergent Neuroimaging in Patients With Sturge-Weber Syndrome Presenting With Acute Neurologic Symptoms. J Child Neurol. 2019 01; 34(1):17-21. PMID: 30378435.
    Citations:    
  52. Qing B, Canovic EP, Mijailovic AS, Jagielska A, Whitfield MJ, Lowe AL, Kelly EH, Turner D, Sahin M, Van Vliet K. PROBING MECHANICAL PROPERTIES OF BRAIN IN A TUBEROUS SCLEROSIS MODEL OF AUTISM. J Biomech Eng. 2018 Oct 22. PMID: 30347048.
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  53. Peters JM, Prohl A, Kapur K, Nath A, Scherrer B, Clancy S, Prabhu SP, Sahin M, Franz DN, Warfield SK, Krueger DA. Longitudinal Effects of Everolimus on White Matter Diffusion in Tuberous Sclerosis Complex. Pediatr Neurol. 2019 01; 90:24-30. PMID: 30424962.
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  54. Yu KH, Miron O, Palmer N, Lemos DR, Fox K, Kou SC, Sahin M, Kohane IS. Data-driven analyses revealed the comorbidity landscape of tuberous sclerosis complex. Neurology. 2018 11 20; 91(21):974-976. PMID: 30333165.
    Citations:    
  55. Tsai PT, Rudolph S, Guo C, Ellegood J, Gibson JM, Schaeffer SM, Mogavero J, Lerch JP, Regehr W, Sahin M. Sensitive Periods for Cerebellar-Mediated Autistic-like Behaviors. Cell Rep. 2018 10 09; 25(2):357-367.e4. PMID: 30304677.
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  56. Hussain SA, Schmid E, Peters JM, Goyal M, Bebin EM, Northrup H, Sahin M, Krueger DA, Wu JY. High vigabatrin dosage is associated with lower risk of infantile spasms relapse among children with tuberous sclerosis complex. Epilepsy Res. 2018 12; 148:1-7. PMID: 30296632.
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  57. Baumer FM, Peters JM, Clancy S, Prohl AK, Prabhu SP, Scherrer B, Jansen FE, Braun KPJ, Sahin M, Stamm A, Warfield SK. Corpus Callosum White Matter Diffusivity Reflects Cumulative Neurological Comorbidity in Tuberous Sclerosis Complex. Cereb Cortex. 2018 10 01; 28(10):3665-3672. PMID: 29939236.
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  58. Srivastava S, Scherrer B, Prohl AK, Filip-Dhima R, Kapur K, Kolevzon A, Buxbaum JD, Berry-Kravis E, Soorya L, Thurm A, Powell CM, Bernstein JA, Warfield SK, Sahin M. Volumetric Analysis of the Basal Ganglia and Cerebellar Structures in Patients with Phelan-McDermid Syndrome. Pediatr Neurol. 2019 01; 90:37-43. PMID: 30396833.
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  59. Howe JR, Bear MF, Golshani P, Klann E, Lipton SA, Mucke L, Sahin M, Silva AJ. The mouse as a model for neuropsychiatric drug development. Curr Biol. 2018 09 10; 28(17):R909-R914. PMID: 30205056.
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  60. Modi ME, Sahin M. A unified circuit for social behavior. Neurobiol Learn Mem. 2019 11; 165:106920. PMID: 30149055.
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  61. Modi ME, Sahin M. The Way Forward for Mechanism-Based Therapeutics in Genetically Defined Neurodevelopmental Disorders. Clin Pharmacol Ther. 2018 10; 104(4):603-606. PMID: 30101418.
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  62. Gökçay Canpolat A, Sahin M, Ediboglu E, Erdogan MF, Güllü S, Demir Ö, Emral R, Çorapçioglu D. Diagnostic accuracy of parathyroid hormone levels in washout samples of suspicious parathyroid adenomas: A single-centre retrospective cohort study. Clin Endocrinol (Oxf). 2018 10; 89(4):489-495. PMID: 30004132.
    Citations:    
  63. Di Nardo A, Sahin M. mTOR'ing across the Cortex by Chopping the Cilia. Neuron. 2018 07 11; 99(1):3-5. PMID: 30001510.
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  64. Gonçalves IDCG, Brecht J, Thelen MP, Rehorst WA, Peters M, Lee HJ, Motameny S, Torres-Benito L, Ebrahimi-Fakhari D, Kononenko NL, Altmüller J, Vilchez D, Sahin M, Wirth B, Kye MJ. Author Correction: Neuronal activity regulates DROSHA via autophagy in spinal muscular atrophy. Sci Rep. 2018 Jul 03; 8(1):10294. PMID: 29967434.
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  65. Charupanit K, Nunez MD, Bernardo D, Bebin M, Krueger DA, Northrup H, Sahin M, Wu JY, Lopour BA. Automated Detection of High Frequency Oscillations in Human Scalp Electroencephalogram. Annu Int Conf IEEE Eng Med Biol Soc. 2018 Jul; 2018:3116-3119. PMID: 30441054.
    Citations:    Fields:    
  66. Gonçalves IDCG, Brecht J, Thelen MP, Rehorst WA, Peters M, Lee HJ, Motameny S, Torres-Benito L, Ebrahimi-Fakhari D, Kononenko NL, Altmüller J, Vilchez D, Sahin M, Wirth B, Kye MJ. Neuronal activity regulates DROSHA via autophagy in spinal muscular atrophy. Sci Rep. 2018 05 21; 8(1):7907. PMID: 29784949.
    Citations:    Fields:    
  67. van der Poest Clement EA, Sahin M, Peters JM. Vigabatrin for Epileptic Spasms and Tonic Seizures in Tuberous Sclerosis Complex. J Child Neurol. 2018 07; 33(8):519-524. PMID: 29687739.
    Citations:    Fields:    
  68. Pinto ALR, Ou Y, Sahin M, Grant PE. Quantitative Apparent Diffusion Coefficient Mapping May Predict Seizure Onset in Children With Sturge-Weber Syndrome. Pediatr Neurol. 2018 07; 84:32-38. PMID: 29753575.
    Citations:    Fields:    
  69. Bernardo D, Nariai H, Hussain SA, Sankar R, Salamon N, Krueger DA, Sahin M, Northrup H, Bebin EM, Wu JY. Visual and semi-automatic non-invasive detection of interictal fast ripples: A potential biomarker of epilepsy in children with tuberous sclerosis complex. Clin Neurophysiol. 2018 07; 129(7):1458-1466. PMID: 29673547.
    Citations:    Fields:    
  70. Srivastava S, Prohl AK, Scherrer B, Kapur K, Krueger DA, Warfield SK, Sahin M. Cerebellar volume as an imaging marker of development in infants with tuberous sclerosis complex. Neurology. 2018 04 24; 90(17):e1493-e1500. PMID: 29572283.
    Citations:    Fields:    
  71. Sundberg M, Tochitsky I, Buchholz DE, Winden K, Kujala V, Kapur K, Cataltepe D, Turner D, Han MJ, Woolf CJ, Hatten ME, Sahin M. Purkinje cells derived from TSC patients display hypoexcitability and synaptic deficits associated with reduced FMRP levels and reversed by rapamycin. Mol Psychiatry. 2018 11; 23(11):2167-2183. PMID: 29449635.
    Citations: 3     Fields:    
  72. O'Leary HM, Kaufmann WE, Barnes KV, Rakesh K, Kapur K, Tarquinio DC, Cantwell NG, Roche KJ, Rose SA, Walco AC, Bruck NM, Bazin GA, Holm IA, Alexander ME, Swanson LC, Baczewski LM, Poon C, Mayor Torres JM, Nelson CA, Sahin M. Placebo-controlled crossover assessment of mecasermin for the treatment of Rett syndrome. Ann Clin Transl Neurol. 2018 03; 5(3):323-332. PMID: 29560377.
    Citations: 3     
  73. Winden KD, Ebrahimi-Fakhari D, Sahin M. Abnormal mTOR Activation in Autism. Annu Rev Neurosci. 2018 07 08; 41:1-23. PMID: 29490194.
    Citations: 1     Fields:    
  74. Yuskaitis CJ, Jones BM, Wolfson RL, Super CE, Dhamne SC, Rotenberg A, Sabatini DM, Sahin M, Poduri A. A mouse model of DEPDC5-related epilepsy: Neuronal loss of Depdc5 causes dysplastic and ectopic neurons, increased mTOR signaling, and seizure susceptibility. Neurobiol Dis. 2018 03; 111:91-101. PMID: 29274432.
    Citations: 3     Fields:    
  75. Kelly E, Schaeffer SM, Dhamne SC, Lipton JO, Lindemann L, Honer M, Jaeschke G, Super CE, Lammers SH, Modi ME, Silverman JL, Dreier JR, Kwiatkowski DJ, Rotenberg A, Sahin M. mGluR5 Modulation of Behavioral and Epileptic Phenotypes in a Mouse Model of Tuberous Sclerosis Complex. Neuropsychopharmacology. 2018 05; 43(6):1457-1465. PMID: 29206810.
    Citations:    Fields:    
  76. Ebrahimi-Fakhari D, Cheng C, Dies K, Diplock A, Pier DB, Ryan CS, Lanpher BC, Hirst J, Chung WK, Sahin M, Rosser E, Darras B, Bennett JT. Clinical and genetic characterization of AP4B1-associated SPG47. . 2018 02; 176(2):311-318. PMID: 29193663.
    Citations: 1     Fields:    
  77. Krueger DA, Sadhwani A, Byars AW, de Vries PJ, Franz DN, Whittemore VH, Filip-Dhima R, Murray D, Kapur K, Sahin M. Everolimus for treatment of tuberous sclerosis complex-associated neuropsychiatric disorders. Ann Clin Transl Neurol. 2017 12; 4(12):877-887. PMID: 29296616.
    Citations: 2     
  78. Davis PE, Filip-Dhima R, Sideridis G, Peters JM, Au KS, Northrup H, Bebin EM, Wu JY, Krueger D, Sahin M. Presentation and Diagnosis of Tuberous Sclerosis Complex in Infants. Pediatrics. 2017 Dec; 140(6). PMID: 29101226.
    Citations: 4     Fields:    Translation:Humans
  79. Ucan B, Sahin M, Kizilgul M, Ozbek M, Ozdemir S, Caliskan M, Cakal E. Serum ghrelin levels in papillary thyroid carcinoma. Arch Endocrinol Metab. 2017 Sept-Oct; 61(5):464-469. PMID: 28977162.
    Citations:    
  80. McDonald NM, Varcin KJ, Bhatt R, Wu JY, Sahin M, Nelson CA, Jeste SS. Early autism symptoms in infants with tuberous sclerosis complex. Autism Res. 2017 Dec; 10(12):1981-1990. PMID: 28801991.
    Citations: 2     Fields:    Translation:Humans
  81. Lipton JO, Boyle LM, Yuan ED, Hochstrasser KJ, Chifamba FF, Nathan A, Tsai PT, Davis F, Sahin M. Aberrant Proteostasis of BMAL1 Underlies Circadian Abnormalities in a Paradigmatic mTOR-opathy. Cell Rep. 2017 07 25; 20(4):868-880. PMID: 28746872.
    Citations: 6     Fields:    Translation:AnimalsCells
  82. Ucan B, Sahin M, Sayki Arslan M, Colak Bozkurt N, Kizilgul M, Güngünes A, Cakal E, Ozbek M. Vitamin D Treatment in Patients with Hashimoto's Thyroiditis may Decrease the Development of Hypothyroidism. Int J Vitam Nutr Res. 2016 Feb; 86(1-2):9-17. PMID: 28697689.
    Citations:    
  83. O'Leary HM, Mayor JM, Kaufmann WE, Sahin M. Classification of respiratory disturbances in Rett Syndrome patients using Restricted Boltzmann Machine. Annu Int Conf IEEE Eng Med Biol Soc. 2017 Jul; 2017:442-445. PMID: 29059905.
    Citations: 1     Fields:    Translation:Humans
  84. Capal JK, Horn PS, Murray DS, Byars AW, Bing NM, Kent B, Bucher LA, Williams ME, O'Kelley S, Pearson DA, Sahin M, Krueger DA. Utility of the Autism Observation Scale for Infants in Early Identification of Autism in Tuberous Sclerosis Complex. Pediatr Neurol. 2017 Oct; 75:80-86. PMID: 28844798.
    Citations: 1     Fields:    Translation:Humans
  85. Srivastava S, Sahin M. Autism spectrum disorder and epileptic encephalopathy: common causes, many questions. J Neurodev Disord. 2017; 9:23. PMID: 28649286.
    Citations: 1     Fields:    
  86. Dhamne SC, Silverman JL, Super CE, Lammers SHT, Hameed MQ, Modi ME, Copping NA, Pride MC, Smith DG, Rotenberg A, Crawley JN, Sahin M. Replicable in vivo physiological and behavioral phenotypes of the Shank3B null mutant mouse model of autism. Mol Autism. 2017; 8:26. PMID: 28638591.
    Citations: 7     Fields:    Translation:HumansAnimals
  87. Dy ME, Waugh JL, Sharma N, O'Leary H, Kapur K, D'Gama AM, Sahin M, Urion DK, Kaufmann WE. Defining Hand Stereotypies in Rett Syndrome: A Movement Disorders Perspective. Pediatr Neurol. 2017 Oct; 75:91-95. PMID: 28838622.
    Citations:    Fields:    Translation:HumansCTClinical Trials
  88. Srivastava S, Gubbels CS, Dies K, Fulton A, Yu T, Sahin M. Increased Survival and Partly Preserved Cognition in a Patient With ACO2-Related Disease Secondary to a Novel Variant. J Child Neurol. 2017 08; 32(9):840-845. PMID: 28545339.
    Citations: 2     Fields:    Translation:Humans
  89. Lam HC, Baglini CV, Lope AL, Parkhitko AA, Liu HJ, Alesi N, Malinowska IA, Ebrahimi-Fakhari D, Saffari A, Yu JJ, Pereira A, Khabibullin D, Ogorek B, Nijmeh J, Kavanagh T, Handen A, Chan SY, Asara JM, Oldham WM, Diaz-Meco MT, Moscat J, Sahin M, Priolo C, Henske EP. p62/SQSTM1 Cooperates with Hyperactive mTORC1 to Regulate Glutathione Production, Maintain Mitochondrial Integrity, and Promote Tumorigenesis. Cancer Res. 2017 06 15; 77(12):3255-3267. PMID: 28512249.
    Citations: 2     Fields:    Translation:AnimalsCells
  90. Sahin M. Comment on: "Comprehensive first-line magnetic resonance imaging in hypertension: experience from a single-center tertiary referral clinic". J Clin Hypertens (Greenwich). 2017 07; 19(7):677. PMID: 28493420.
    Citations:    Fields:    
  91. Agulnik A, Kelly DP, Bruccoleri R, Yuskaitis C, Ebrahimi-Fakhari D, Sahin M, Burns MM, Kohane DS. Combination Clearance Therapy and Barbiturate Coma for Severe Carbamazepine Overdose. Pediatrics. 2017 May; 139(5). PMID: 28557718.
    Citations:    Fields:    Translation:HumansPHPublic Health
  92. Capal JK, Bernardino-Cuesta B, Horn PS, Murray D, Byars AW, Bing NM, Kent B, Pearson DA, Sahin M, Krueger DA. Influence of seizures on early development in tuberous sclerosis complex. Epilepsy Behav. 2017 05; 70(Pt A):245-252. PMID: 28457992.
    Citations: 10     Fields:    Translation:HumansCTClinical Trials
  93. Modi ME, Sahin M. Translational use of event-related potentials to assess circuit integrity in ASD. Nat Rev Neurol. 2017 03; 13(3):160-170. PMID: 28211449.
    Citations: 1     Fields:    
  94. Ercan E, Han JM, Di Nardo A, Winden K, Han MJ, Hoyo L, Saffari A, Leask A, Geschwind DH, Sahin M. Neuronal CTGF/CCN2 negatively regulates myelination in a mouse model of tuberous sclerosis complex. J Exp Med. 2017 03 06; 214(3):681-697. PMID: 28183733.
    Citations: 6     Fields:    Translation:AnimalsCells
  95. Ebrahimi-Fakhari D, Saffari A, Wahlster L, Sahin M. Using tuberous sclerosis complex to understand the impact of MTORC1 signaling on mitochondrial dynamics and mitophagy in neurons. Autophagy. 2017 Apr 03; 13(4):754-756. PMID: 28121223.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  96. Saylam G, Sahin M, Demiral D, Bayir Ö, Yüceege MB, Çadalli Tatar E, Korkmaz MH. Does CPAP treatment affect the voice? Turk J Med Sci. 2016 Dec 20; 46(6):1749-1754. PMID: 28081322.
    Citations:    
  97. Ebrahimi-Fakhari D, Saffari A, Wahlster L, DiNardo A, Turner D, Lewis TL, Conrad C, Rothberg JM, Lipton JO, Kölker S, Hoffmann GF, Han MJ, Polleux F, Sahin M. Impaired Mitochondrial Dynamics And Mitophagy In Neuronal Models Of Tuberous Sclerosis Complex. Cell Rep. 2016 11 15; 17(8):2162. PMID: 27851977.
    Citations: 3     Fields:    
  98. Huang L, Couto JA, Pinto A, Alexandrescu S, Madsen JR, Greene AK, Sahin M, Bischoff J. Somatic GNAQ Mutation is Enriched in Brain Endothelial Cells in Sturge-Weber Syndrome. Pediatr Neurol. 2017 02; 67:59-63. PMID: 27919468.
    Citations: 2     Fields:    Translation:HumansCells
  99. Ebrahimi-Fakhari D, Saffari A, Wahlster L, Di Nardo A, Turner D, Lewis TL, Conrad C, Rothberg JM, Lipton JO, Kölker S, Hoffmann GF, Han MJ, Polleux F, Sahin M. Impaired Mitochondrial Dynamics and Mitophagy in Neuronal Models of Tuberous Sclerosis Complex. Cell Rep. 2016 10 18; 17(4):1053-1070. PMID: 27760312.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  100. Arslan MS, Tutal E, Sahin M, Karakose M, Ucan B, Ozturk G, Cakal E, Biyikli Gencturk Z, Ozbek M, Delibasi T. Effect of lifestyle interventions with or without metformin therapy on serum levels of osteoprotegerin and receptor activator of nuclear factor kappa B ligand in patients with prediabetes. Endocrine. 2017 Feb; 55(2):410-415. PMID: 27743302.
    Citations:    
  101. Canovic EP, Qing B, Mijailovic AS, Jagielska A, Whitfield MJ, Kelly E, Turner D, Sahin M, Van Vliet KJ. Characterizing Multiscale Mechanical Properties of Brain Tissue Using Atomic Force Microscopy, Impact Indentation, and Rheometry. J Vis Exp. 2016 09 06; (115). PMID: 27684097.
    Citations: 2     Fields:    Translation:Humans
  102. Jeste SS, Varcin KJ, Hellemann GS, Gulsrud AC, Bhatt R, Kasari C, Wu JY, Sahin M, Nelson CA. Symptom profiles of autism spectrum disorder in tuberous sclerosis complex. Neurology. 2016 Aug 23; 87(8):766-72. PMID: 27440144.
    Citations: 10     Fields:    Translation:Humans
  103. Crall C, Valle M, Kapur K, Dies KA, Liang MG, Sahin M, Huang JT. Effect of Angiofibromas on Quality of Life and Access to Care in Tuberous Sclerosis Patients and Their Caregivers. Pediatr Dermatol. 2016 Sep; 33(5):518-25. PMID: 27436143.
    Citations:    Fields:    Translation:Humans
  104. Weisleder P, Gospe SM, Ng YT, Sahin M. The Pediatric Neurology Trainee Publication Award for 2015. Pediatr Neurol. 2016 Oct; 63:1-2. PMID: 27543367.
    Citations:    
  105. Weisleder P, Gospe SM, Ng YT, Sahin M. The Pediatric Neurology Trainee Publication Award for 2015. Pediatr Neurol. 2016 10; 63:1-2. PMID: 28847386.
    Citations:    Fields:    Translation:Humans
  106. Sun Y, Lipton JO, Boyle LM, Madsen JR, Goldenberg MC, Pascual-Leone A, Sahin M, Rotenberg A. Direct current stimulation induces mGluR5-dependent neocortical plasticity. Ann Neurol. 2016 08; 80(2):233-46. PMID: 27315032.
    Citations: 6     Fields:    Translation:HumansAnimals
  107. Sahin M, Emral R. Letter to the Editor: Comment on "Thyroid stimulating antibodies are highly prevalent in Hashimoto thyroiditis and associated orbitopathy" Dear Editor. J Clin Endocrinol Metab. 2016 06; 101(6):L68. PMID: 27255721.
    Citations:    
  108. Sahin M, Henske EP, Manning BD, Ess KC, Bissler JJ, Klann E, Kwiatkowski DJ, Roberds SL, Silva AJ, Hillaire-Clarke CS, Young LR, Zervas M, Mamounas LA. Advances and Future Directions for Tuberous Sclerosis Complex Research: Recommendations From the 2015 Strategic Planning Conference. Pediatr Neurol. 2016 07; 60:1-12. PMID: 27267556.
    Citations: 9     Fields:    Translation:HumansAnimals
  109. Wertz MH, Winden K, Neveu P, Ng SY, Ercan E, Sahin M. Cell-type-specific miR-431 dysregulation in a motor neuron model of spinal muscular atrophy. Hum Mol Genet. 2016 06 01; 25(11):2168-2181. PMID: 27005422.
    Citations:    
  110. Pinto A, Sahin M, Pearl PL. Epileptogenesis in neurocutaneous disorders with focus in Sturge Weber syndrome. F1000Res. 2016; 5. PMID: 27019697.
    Citations: 4     
  111. Comi AM, Sahin M, Hammill A, Kaplan EH, Juhász C, North P, Ball KL, Levin AV, Cohen B, Morris J, Lo W, Roach ES. Leveraging a Sturge-Weber Gene Discovery: An Agenda for Future Research. Pediatr Neurol. 2016 05; 58:12-24. PMID: 27268758.
    Citations: 2     Fields:    Translation:HumansAnimals
  112. Tai DJ, Ragavendran A, Manavalan P, Stortchevoi A, Seabra CM, Erdin S, Collins RL, Blumenthal I, Chen X, Shen Y, Sahin M, Zhang C, Lee C, Gusella JF, Talkowski ME. Engineering microdeletions and microduplications by targeting segmental duplications with CRISPR. Nat Neurosci. 2016 Mar; 19(3):517-22. PMID: 26829649.
    Citations: 9     Fields:    Translation:HumansCells
  113. Uçan B, Sahin M, Özbek M, Arslan MS, Çakal E, Uçan B, Ant Ö, Sirvan L, Yildirim MU, Dilli A, Delibasi T. What is your diagnosis? J Turk Ger Gynecol Assoc. 2016; 17(1):58-9. PMID: 27026781.
    Citations:    
  114. Ebrahimi-Fakhari D, Saffari A, Wahlster L, Lu J, Byrne S, Hoffmann GF, Jungbluth H, Sahin M. Congenital disorders of autophagy: an emerging novel class of inborn errors of neuro-metabolism. Brain. 2016 Feb; 139(Pt 2):317-37. PMID: 26715604.
    Citations: 14     Fields:    Translation:HumansCells
  115. Gholipour A, Afacan O, Aganj I, Scherrer B, Prabhu SP, Sahin M, Warfield SK. Super-resolution reconstruction in frequency, image, and wavelet domains to reduce through-plane partial voluming in MRI. Med Phys. 2015 Dec; 42(12):6919-32. PMID: 26632048.
    Citations: 2     Fields:    Translation:Humans
  116. Pinto AL, Chen L, Friedman R, Grant PE, Poduri A, Takeoka M, Prabhu SP, Sahin M. Sturge-Weber Syndrome: Brain Magnetic Resonance Imaging and Neuropathology Findings. Pediatr Neurol. 2016 05; 58:25-30. PMID: 26706049.
    Citations: 9     Fields:    Translation:Humans
  117. Tyburczy ME, Dies KA, Glass J, Camposano S, Chekaluk Y, Thorner AR, Lin L, Krueger D, Franz DN, Thiele EA, Sahin M, Kwiatkowski DJ. Mosaic and Intronic Mutations in TSC1/TSC2 Explain the Majority of TSC Patients with No Mutation Identified by Conventional Testing. PLoS Genet. 2015 Nov; 11(11):e1005637. PMID: 26540169.
    Citations: 29     Fields:    Translation:Humans
  118. Sahin M, Sur M. Genes, circuits, and precision therapies for autism and related neurodevelopmental disorders. Science. 2015 Nov 20; 350(6263). PMID: 26472761.
    Citations: 38     Fields:    Translation:HumansAnimalsCells
  119. Peters JM, Prohl AK, Tomas-Fernandez XK, Taquet M, Scherrer B, Prabhu SP, Lidov HG, Singh JM, Jansen FE, Braun KP, Sahin M, Warfield SK, Stamm A. Tubers are neither static nor discrete: Evidence from serial diffusion tensor imaging. Neurology. 2015 Nov 03; 85(18):1536-45. PMID: 26432846.
    Citations: 4     Fields:    Translation:Humans
  120. Wu JY, Peters JM, Goyal M, Krueger D, Sahin M, Northrup H, Au KS, Cutter G, Bebin EM. Clinical Electroencephalographic Biomarker for Impending Epilepsy in Asymptomatic Tuberous Sclerosis Complex Infants. Pediatr Neurol. 2016 Jan; 54:29-34. PMID: 26498039.
    Citations: 15     Fields:    Translation:Humans
  121. Scherrer B, Schwartzman A, Taquet M, Sahin M, Prabhu SP, Warfield SK. Characterizing brain tissue by assessment of the distribution of anisotropic microstructural environments in diffusion-compartment imaging (DIAMOND). Magn Reson Med. 2016 09; 76(3):963-77. PMID: 26362832.
    Citations: 11     Fields:    Translation:HumansAnimals
  122. Sundberg M, Sahin M. Cerebellar Development and Autism Spectrum Disorder in Tuberous Sclerosis Complex. J Child Neurol. 2015 Dec; 30(14):1954-62. PMID: 26303409.
    Citations: 5     Fields:    Translation:Animals
  123. Nie D, Chen Z, Ebrahimi-Fakhari D, Di Nardo A, Julich K, Robson VK, Cheng YC, Woolf CJ, Heiman M, Sahin M. The Stress-Induced Atf3-Gelsolin Cascade Underlies Dendritic Spine Deficits in Neuronal Models of Tuberous Sclerosis Complex. J Neurosci. 2015 Jul 29; 35(30):10762-72. PMID: 26224859.
    Citations: 9     Fields:    Translation:AnimalsCells
  124. Wertz MH, Sahin M. Developing therapies for spinal muscular atrophy. Ann N Y Acad Sci. 2016 02; 1366(1):5-19. PMID: 26173388.
    Citations: 6     Fields:    Translation:HumansAnimals
  125. Kloth AD, Badura A, Li A, Cherskov A, Connolly SG, Giovannucci A, Bangash MA, Grasselli G, Peñagarikano O, Piochon C, Tsai PT, Geschwind DH, Hansel C, Sahin M, Takumi T, Worley PF, Wang SS. Cerebellar associative sensory learning defects in five mouse autism models. Elife. 2015 Jul 09; 4:e06085. PMID: 26158416.
    Citations: 18     Fields:    Translation:AnimalsCells
  126. Davis PE, Peters JM, Krueger DA, Sahin M. Tuberous Sclerosis: A New Frontier in Targeted Treatment of Autism. Neurotherapeutics. 2015 Jul; 12(3):572-83. PMID: 25986747.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  127. Neul JL, Sahin M. Therapeutic Advances in Autism and Other Neurodevelopmental Disorders. Neurotherapeutics. 2015 Jul; 12(3):519-20. PMID: 26076992.
    Citations: 1     Fields:    Translation:Humans
  128. Unsal IO, Ginis Z, Pinarli FA, Albayrak A, Cakal E, Sahin M, Delibasi T. Comparison of therapeutic characteristics of islet cell transplantation simultaneous with pancreatic mesenchymal stem cell transplantation in rats with Type 1 diabetes mellitus. Stem Cell Rev Rep. 2015 Jun; 11(3):526-32. PMID: 25297071.
    Citations:    
  129. Delibasi T, Arslan MS, Çakal E, Sahin M, Topaloglu O, Tutal E, Ünsal IÖ, Karbek B, Uçan B, Güngünes A, Karaköse M, Çaliskan M, Demirci T, Tabur G, Özbek M. Hyperprolactinemia has no effect on plasma ghrelin levels in patients with prolactinoma. J Turk Ger Gynecol Assoc. 2015; 16(2):86-90. PMID: 26097390.
    Citations:    
  130. Varcin KJ, Nelson CA, Ko J, Sahin M, Wu JY, Jeste SS. Visual Evoked Potentials as a Readout of Cortical Function in Infants With Tuberous Sclerosis Complex. J Child Neurol. 2016 Feb; 31(2):195-202. PMID: 26018199.
    Citations: 5     Fields:    Translation:Humans
  131. Tatar EC, Sahin M, Demiral D, Bayir O, Saylam G, Ozdek A, Korkmaz MH. Normative Values of Voice Analysis Parameters With Respect to Menstrual Cycle in Healthy Adult Turkish Women. J Voice. 2016 May; 30(3):322-8. PMID: 26003887.
    Citations: 2     Fields:    Translation:Humans
  132. Lipton JO, Yuan ED, Boyle LM, Ebrahimi-Fakhari D, Kwiatkowski E, Nathan A, Güttler T, Davis F, Asara JM, Sahin M. The Circadian Protein BMAL1 Regulates Translation in Response to S6K1-Mediated Phosphorylation. Cell. 2015 May 21; 161(5):1138-1151. PMID: 25981667.
    Citations: 51     Fields:    Translation:AnimalsCells
  133. Ng YT, Gospe SM, Sahin M. Pediatric Neurology 2014 Trainee Publication Award Winner: Dr. Mitchel T. Williams. Pediatr Neurol. 2015 Aug; 53(2):103-4. PMID: 26047694.
    Citations:    Fields:    Translation:Humans
  134. DiMario FJ, Sahin M, Ebrahimi-Fakhari D. Tuberous sclerosis complex. Pediatr Clin North Am. 2015 Jun; 62(3):633-48. PMID: 26022167.
    Citations: 16     Fields:    Translation:HumansCells
  135. Ebrahimi-Fakhari D, Sahin M. Autism and the synapse: emerging mechanisms and mechanism-based therapies. Curr Opin Neurol. 2015 Apr; 28(2):91-102. PMID: 25695134.
    Citations: 34     Fields:    Translation:HumansAnimalsCells
  136. Akula JD, Noonan ER, Di Nardo A, Favazza TL, Zhang N, Sahin M, Hansen RM, Fulton AB. Vigabatrin can enhance electroretinographic responses in pigmented and albino rats. Doc Ophthalmol. 2015 Aug; 131(1):1-11. PMID: 25761928.
    Citations:    Fields:    Translation:AnimalsCells
  137. Im K, Ahtam B, Haehn D, Peters JM, Warfield SK, Sahin M, Ellen Grant P. Altered Structural Brain Networks in Tuberous Sclerosis Complex. Cereb Cortex. 2016 May; 26(5):2046-58. PMID: 25750257.
    Citations: 3     Fields:    Translation:Humans
  138. Baumer FM, Song JW, Mitchell PD, Pienaar R, Sahin M, Grant PE, Takahashi E. Longitudinal changes in diffusion properties in white matter pathways of children with tuberous sclerosis complex. Pediatr Neurol. 2015 Jun; 52(6):615-23. PMID: 25817702.
    Citations: 2     Fields:    Translation:HumansCells
  139. Karakose M, Karbek B, Sahin M, Arslan MS, Topaloglu O, Erden G, Demirci T, Caliskan M, Delibasi T. The association of autoimmune thyroiditis and non-functional adrenal incidentalomas with insulin resistance. Arch Endocrinol Metab. 2015 Feb; 59(1):42-6. PMID: 25926113.
    Citations:    
  140. Arslan MS, Topaloglu O, Ucan B, Karakose M, Karbek B, Tutal E, Caliskan M, Ginis Z, Cakal E, Sahin M, Ozbek M, Delibasi T. Isolated vitamin D deficiency is not associated with nonthyroidal illness syndrome, but with thyroid autoimmunity. ScientificWorldJournal. 2015; 2015:239815. PMID: 25654127.
    Citations:    
  141. Dies KA, Sahin M. Genetics of neurocutaneous disorders: basic principles of inheritance as they apply to neurocutaneous syndromes. Handb Clin Neurol. 2015; 132:3-8. PMID: 26564068.
    Citations:    Fields:    Translation:Humans
  142. Leech JD, Lammers SH, Goldman S, Auricchio N, Bronson RT, Kwiatkowski DJ, Sahin M. A vascular model of Tsc1 deficiency accelerates renal tumor formation with accompanying hemangiosarcomas. Mol Cancer Res. 2015 Mar; 13(3):548-55. PMID: 25548102.
    Citations: 3     Fields:    Translation:AnimalsCells
  143. Ucan B, Delibasi T, Cakal E, Arslan MS, Bozkurt NC, Demirci T, Ozbek M, Sahin M. Papillary thyroid cancer case masked by subacute thyroiditis. Arq Bras Endocrinol Metabol. 2014 Nov; 58(8):851-4. PMID: 25465609.
    Citations:    
  144. Lipton JO, Sahin M. The neurology of mTOR. Neuron. 2014 Oct 22; 84(2):275-91. PMID: 25374355.
    Citations: 86     Fields:    Translation:HumansAnimalsCells
  145. de Vries PJ, Whittemore VH, Leclezio L, Byars AW, Dunn D, Ess KC, Hook D, King BH, Sahin M, Jansen A. Tuberous sclerosis associated neuropsychiatric disorders (TAND) and the TAND Checklist. Pediatr Neurol. 2015 Jan; 52(1):25-35. PMID: 25532776.
    Citations: 31     Fields:    Translation:Humans
  146. Sahin M, Bilgen C, Tasbakan MS, Midilli R, Basoglu OK. A clinical prediction formula for apnea-hypopnea index. Int J Otolaryngol. 2014; 2014:438376. PMID: 25349613.
    Citations:    
  147. Ebrahimi-Fakhari D, Wahlster L, Sahin M. Parkinson's disease: A disorder of axonal mitophagy? Mov Disord. 2014 Nov; 29(13):1582. PMID: 25256171.
    Citations: 1     Fields:    Translation:AnimalsCells
  148. Jamuar SS, Lam AT, Kircher M, D'Gama AM, Wang J, Barry BJ, Zhang X, Hill RS, Partlow JN, Rozzo A, Servattalab S, Mehta BK, Topcu M, Amrom D, Andermann E, Dan B, Parrini E, Guerrini R, Scheffer IE, Berkovic SF, Leventer RJ, Shen Y, Wu BL, Barkovich AJ, Sahin M, Chang BS, Bamshad M, Nickerson DA, Shendure J, Poduri A, Yu TW, Walsh CA. Somatic mutations in cerebral cortical malformations. N Engl J Med. 2014 Aug 21; 371(8):733-43. PMID: 25140959.
    Citations: 60     Fields:    Translation:Humans
  149. Sahin M. Gene therapy for childhood neurological disease. Pediatr Neurol. 2014 Nov; 51(5):595-6. PMID: 25439574.
    Citations: 1     Fields:    Translation:Humans
  150. Greene-Colozzi EA, Sadowski AR, Chadwick E, Tsai PT, Sahin M. Both maternal and pup genotype influence ultrasonic vocalizations and early developmental milestones in tsc2 (+/-) mice. Epilepsy Res Treat. 2014; 2014:784137. PMID: 25165580.
    Citations: 1     
  151. Kye MJ, Niederst ED, Wertz MH, Gonçalves Ido C, Akten B, Dover KZ, Peters M, Riessland M, Neveu P, Wirth B, Kosik KS, Sardi SP, Monani UR, Passini MA, Sahin M. SMN regulates axonal local translation via miR-183/mTOR pathway. Hum Mol Genet. 2014 Dec 01; 23(23):6318-31. PMID: 25055867.
    Citations: 28     Fields:    Translation:AnimalsCells
  152. Olson H, Shen Y, Avallone J, Sheidley BR, Pinsky R, Bergin AM, Berry GT, Duffy FH, Eksioglu Y, Harris DJ, Hisama FM, Ho E, Irons M, Jacobsen CM, James P, Kothare S, Khwaja O, Lipton J, Loddenkemper T, Markowitz J, Maski K, Megerian JT, Neilan E, Raffalli PC, Robbins M, Roberts A, Roe E, Rollins C, Sahin M, Sarco D, Schonwald A, Smith SE, Soul J, Stoler JM, Takeoka M, Tan WH, Torres AR, Tsai P, Urion DK, Weissman L, Wolff R, Wu BL, Miller DT, Poduri A. Copy number variation plays an important role in clinical epilepsy. Ann Neurol. 2014 Jun; 75(6):943-58. PMID: 24811917.
    Citations: 33     Fields:    Translation:Humans
  153. Spurling Jeste S, Wu JY, Senturk D, Varcin K, Ko J, McCarthy B, Shimizu C, Dies K, Vogel-Farley V, Sahin M, Nelson CA. Early developmental trajectories associated with ASD in infants with tuberous sclerosis complex. Neurology. 2014 Jul 08; 83(2):160-8. PMID: 24920850.
    Citations: 17     Fields:    Translation:HumansCells
  154. Kawasaki J, Aegerter S, Fevurly RD, Mammoto A, Mammoto T, Sahin M, Mably JD, Fishman SJ, Chan J. RASA1 functions in EPHB4 signaling pathway to suppress endothelial mTORC1 activity. J Clin Invest. 2014 Jun; 124(6):2774-84. PMID: 24837431.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  155. Arslan MS, Topaloglu O, Sahin M, Tutal E, Gungunes A, Cakir E, Ozturk IU, Karbek B, Ucan B, Ginis Z, Cakal E, Ozbek M, Delibasi T. Preclinical atherosclerosis in patients with prolactinoma. Endocr Pract. 2014 May; 20(5):447-51. PMID: 24325995.
    Citations:    
  156. Gungunes A, Sahin M, Demirci T, Ucan B, Cakir E, Arslan MS, Unsal IO, Karbek B, Caliskan M, Ozbek M, Cakal E, Delibasi T. Cushing's syndrome in type 2 diabetes patients with poor glycemic control. Endocrine. 2014 Dec; 47(3):895-900. PMID: 24740545.
    Citations:    
  157. Acar F, Sahin M, Alptekin H, Yilmaz H, Kafali ME. Surgical treatment of giant liver hydatid cysts: comparison of cystojejunostomy and partial cystectomy. Surg Today. 2014 Nov; 44(11):2065-71. PMID: 24664490.
    Citations:    
  158. Clifford MA, Athar W, Leonard CE, Russo A, Sampognaro PJ, Van der Goes MS, Burton DA, Zhao X, Lalchandani RR, Sahin M, Vicini S, Donoghue MJ. EphA7 signaling guides cortical dendritic development and spine maturation. Proc Natl Acad Sci U S A. 2014 Apr 01; 111(13):4994-9. PMID: 24707048.
    Citations: 11     Fields:    Translation:AnimalsCells
  159. Di Nardo A, Wertz MH, Kwiatkowski E, Tsai PT, Leech JD, Greene-Colozzi E, Goto J, Dilsiz P, Talos DM, Clish CB, Kwiatkowski DJ, Sahin M. Neuronal Tsc1/2 complex controls autophagy through AMPK-dependent regulation of ULK1. Hum Mol Genet. 2014 Jul 15; 23(14):3865-74. PMID: 24599401.
    Citations: 23     Fields:    Translation:HumansAnimalsCells
  160. Kong SW, Sahin M, Collins CD, Wertz MH, Campbell MG, Leech JD, Krueger D, Bear MF, Kunkel LM, Kohane IS. Divergent dysregulation of gene expression in murine models of fragile X syndrome and tuberous sclerosis. Mol Autism. 2014 Feb 24; 5(1):16. PMID: 24564913.
    Citations: 6     Fields:    
  161. Roach ES, Gospe S, Ng YT, Sahin M. Trust but verify: the introduction of plagiarism detection software. Pediatr Neurol. 2014 Apr; 50(4):287. PMID: 24630278.
    Citations: 1     Fields:    
  162. Topaloglu O, Sayki Arslan M, Turak O, Ginis Z, Sahin M, Cebeci M, Ucan B, Cakir E, Karbek B, Ozbek M, Cakal E, Delibasi T. Three noninvasive methods in the evaluation of subclinical cardiovascular disease in patients with acromegaly: epicardial fat thickness, aortic stiffness and serum cell adhesion molecules. Clin Endocrinol (Oxf). 2014 May; 80(5):726-34. PMID: 24164445.
    Citations:    
  163. Jülich K, Sahin M. Mechanism-based treatment in tuberous sclerosis complex. Pediatr Neurol. 2014 Apr; 50(4):290-6. PMID: 24486221.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  164. Karaköse M, Cakal E, Topaloglu O, Arslan MS, Ginis Z, Sahin M, Delibaii T. Is there a link between polycystic ovary syndrome and non-thyroidal illness syndrome? J Turk Ger Gynecol Assoc. 2013; 14(4):216-20. PMID: 24592109.
    Citations:    
  165. Topaloglu O, Arslan MS, Karakose M, Ucan B, Ginis Z, Cakir E, Akkaymak ET, Sahin M, Ozbek M, Cakal E, Delibasi T. Is there any association between thrombosis and tissue factor pathway inhibitor levels in patients with vitamin D deficiency? Clin Appl Thromb Hemost. 2015 Jul; 21(5):428-33. PMID: 24203351.
    Citations:    
  166. Taquet M, Scherrer B, Commowick O, Peters JM, Sahin M, Macq B, Warfield SK. A mathematical framework for the registration and analysis of multi-fascicle models for population studies of the brain microstructure. IEEE Trans Med Imaging. 2014 Feb; 33(2):504-17. PMID: 24235301.
    Citations: 11     Fields:    Translation:Humans
  167. Topaloglu O, Ucan B, Demirci T, Sayki Arslan M, Saylam G, Onder E, Gultekin S, Dilli A, Sahin M, Cakal E, Ozbek M, Delibasi T. Solitary fibrous tumor of neck mimicking cold thyroid nodule in 99m tc thyroid scintigraphy. Case Rep Endocrinol. 2013; 2013:805745. PMID: 24194989.
    Citations:    
  168. Peters JM, Taquet M, Prohl AK, Scherrer B, van Eeghen AM, Prabhu SP, Sahin M, Warfield SK. Diffusion tensor imaging and related techniques in tuberous sclerosis complex: review and future directions. Future Neurol. 2013 Sep; 8(5):583-597. PMID: 24489482.
    Citations: 10     
  169. Zhang J, Kim J, Alexander A, Cai S, Tripathi DN, Dere R, Tee AR, Tait-Mulder J, Di Nardo A, Han JM, Kwiatkowski E, Dunlop EA, Dodd KM, Folkerth RD, Faust PL, Kastan MB, Sahin M, Walker CL. A tuberous sclerosis complex signalling node at the peroxisome regulates mTORC1 and autophagy in response to ROS. Nat Cell Biol. 2013 Oct; 15(10):1186-96. PMID: 23955302.
    Citations: 64     Fields:    Translation:HumansAnimalsCells
  170. Sayki Arslan M, Sahin M, Topaloglu O, Tutal E, Karakose M, Gungunes A, Cakal E, Ozbek M, Delibasi T. Hyperprolactinaemia associated with increased thyroid volume and autoimmune thyroiditis in patients with prolactinoma. Clin Endocrinol (Oxf). 2013 Dec; 79(6):882-6. PMID: 23551036.
    Citations:    
  171. Bozkurt NC, Karbek B, Ucan B, Sahin M, Cakal E, Ozbek M, Delibasi T. The association between severity of vitamin D deficiency and Hashimoto's thyroiditis. Endocr Pract. 2013 May-Jun; 19(3):479-84. PMID: 23337162.
    Citations:    
  172. Dimitriadi M, Kye MJ, Kalloo G, Yersak JM, Sahin M, Hart AC. The neuroprotective drug riluzole acts via small conductance Ca2+-activated K+ channels to ameliorate defects in spinal muscular atrophy models. J Neurosci. 2013 Apr 10; 33(15):6557-62. PMID: 23575853.
    Citations: 10     Fields:    Translation:AnimalsCells
  173. Peters JM, Taquet M, Vega C, Jeste SS, Fernández IS, Tan J, Nelson CA, Sahin M, Warfield SK. Brain functional networks in syndromic and non-syndromic autism: a graph theoretical study of EEG connectivity. BMC Med. 2013 Feb 27; 11:54. PMID: 23445896.
    Citations: 44     Fields:    Translation:Humans
  174. Weisenfeld NI, Peters JM, Tsai PT, Prabhu SP, Dies KA, Sahin M, Warfield SK. A magnetic resonance imaging study of cerebellar volume in tuberous sclerosis complex. Pediatr Neurol. 2013 Feb; 48(2):105-10. PMID: 23337002.
    Citations: 9     Fields:    Translation:Humans
  175. Fogarasi A, Loddenkemper T, Mellado C, Tuxhorn I, Evers G, Sarco D, Burgess RC, Halász P, Barsis P, Gyorsok Z, Gyimesi C, Kóbor J, Siegler Z, Janszky J, Jakus R, Rásonyi G, Ebner A, Woermann FG, Sahin M. Sturge-Weber syndrome: clinical and radiological correlates in 86 patients. Ideggyogy Sz. 2013 Jan 30; 66(1-2):53-7. PMID: 23607230.
    Citations: 1     Fields:    Translation:Humans
  176. Lipton J, Sahin M. Fragile X syndrome therapeutics: translation, meet translational medicine. Neuron. 2013 Jan 23; 77(2):212-3. PMID: 23352156.
    Citations: 3     Fields:    
  177. Scherrer B, Schwartzman A, Taquet M, Prabhu SP, Sahin M, Akhondi-Asl A, Warfield SK. Characterizing the distribution of anisotropic micro-structural environments with diffusion-weighted imaging (DIAMOND). Med Image Comput Comput Assist Interv. 2013; 16(Pt 3):518-26. PMID: 24505801.
    Citations: 6     Fields:    Translation:Cells
  178. Tsai PT, Greene-Colozzi E, Goto J, Anderl S, Kwiatkowski DJ, Sahin M. Prenatal rapamycin results in early and late behavioral abnormalities in wildtype C57BL/6 mice. Behav Genet. 2013 Jan; 43(1):51-9. PMID: 23229624.
    Citations: 9     Fields:    Translation:AnimalsPHPublic Health
  179. Cakir E, Sahin M, Topaloglu O, Colak NB, Karbek B, Gungunes A, Arslan MS, Unsal IO, Tutal E, Ucan B, Delibasi T. The relationship between LH and thyroid volume in patients with PCOS. J Ovarian Res. 2012 Dec 11; 5(1):43. PMID: 23231775.
    Citations:    
  180. Jeste SS, Hirsch S, Vogel-Farley V, Norona A, Navalta MC, Gregas MC, Prabhu SP, Sahin M, Nelson CA. Atypical face processing in children with tuberous sclerosis complex. J Child Neurol. 2013 Dec; 28(12):1569-76. PMID: 23143725.
    Citations: 5     Fields:    Translation:Humans
  181. Tsai PT, Hull C, Chu Y, Greene-Colozzi E, Sadowski AR, Leech JM, Steinberg J, Crawley JN, Regehr WG, Sahin M. Autistic-like behaviour and cerebellar dysfunction in Purkinje cell Tsc1 mutant mice. Nature. 2012 Aug 30; 488(7413):647-51. PMID: 22763451.
    Citations: 210     Fields:    Translation:AnimalsCells
  182. Yuan E, Tsai PT, Greene-Colozzi E, Sahin M, Kwiatkowski DJ, Malinowska IA. Graded loss of tuberin in an allelic series of brain models of TSC correlates with survival, and biochemical, histological and behavioral features. Hum Mol Genet. 2012 Oct 01; 21(19):4286-300. PMID: 22752306.
    Citations: 17     Fields:    Translation:HumansAnimals
  183. Poduri A, Chopra SS, Neilan EG, Elhosary PC, Kurian MA, Meyer E, Barry BJ, Khwaja OS, Salih MA, Stödberg T, Scheffer IE, Maher ER, Sahin M, Wu BL, Berry GT, Walsh CA, Picker J, Kothare SV. Homozygous PLCB1 deletion associated with malignant migrating partial seizures in infancy. Epilepsia. 2012 Aug; 53(8):e146-50. PMID: 22690784.
    Citations: 20     Fields:    Translation:Humans
  184. Lewis WW, Sahin M, Scherrer B, Peters JM, Suarez RO, Vogel-Farley VK, Jeste SS, Gregas MC, Prabhu SP, Nelson CA, Warfield SK. Impaired language pathways in tuberous sclerosis complex patients with autism spectrum disorders. Cereb Cortex. 2013 Jul; 23(7):1526-32. PMID: 22661408.
    Citations: 22     Fields:    Translation:HumansCells