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Asim Kumar Mandal, Ph.D.

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Biography
Unversity of Calcutta, Calcutta, INDIAB.Sc.10/1983Chemistry (major), Physics, Mathematics, English
University of Calcutta, Calcutta, INDIAM.Sc.11/1986Biochemistry and Molecular Biology
University of Calcutta, Bose Institute, Calcutta, INDIAPh.D.08/1996Biochemistry and Molecular Biology
Indian Institute of Chemical Biology, Calcutta, INDIAResearch Associate11/1996Physical mapping of Vibrio cholerae whole genome
National Institutes of Health, NICHD, Bethesda, USAVisiting Fellow05/2001Cell Biology, Biochemistry, Molecular Biology
Massachusetts General Hospital (MGH), Massachusetts, USAResearch Fellow12/2006Cell Biology
Massachusetts General Hospital (MGH), Massachusetts, USAInstructor of Medicine06/2007Cell Biology
Beth Israel Deaconess Medical Center (BIDMC), Boston, USAResearch Fellow08/2008Gene therapy
Brigham and Women's Hospital (BWH), Boston, USAResearch ScientistCurrentCell Biology, Molcular Biology, Biochemistry

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Boocock J, Leask M, Okada Y, Matsuo H, Kawamura Y, Shi Y, Li C, Mount DB, Mandal AK, Wang W, Cadzow M, Gosling AL, Major TJ, Horsfield JA, Choi HK, Fadason T, O'Sullivan J, Stahl EA, Merriman TR. Genomic dissection of 43 serum urate-associated loci provides multiple insights into molecular mechanisms of urate control. Hum Mol Genet. 2020 Apr 15; 29(6):923-943. PMID: 31985003.
    Citations: 1     Fields:    
  2. Mandal AK, Mount DB. Interaction Between ITM2B and GLUT9 Links Urate Transport to Neurodegenerative Disorders. Frontiers in Physiology. 2019; 10(October):1-16. View Publication.
  3. Mandal AK, Mount DB. Interaction Between ITM2B and GLUT9 Links Urate Transport to Neurodegenerative Disorders. Front Physiol. 2019; 10:1323. PMID: 31695625.
    Citations:    
  4. Mandal AK, Mount DB, Merriman T. Journal of the American Society of Nephrology (JASN). Insulin: Genetic and Physiological Influences on Human Uric Acid Homeostasis. 2018; 29(October):244. View Publication.
  5. Tanner C, Boocock J, Stahl EA, Dobbyn A, Mandal AK, Cadzow M, Phipps-Green AJ, Topless RK, Hindmarsh JH, Stamp LK, Dalbeth N, Choi HK, Mount DB, Merriman TR. Population-Specific Resequencing Associates the ATP-Binding Cassette Subfamily C Member 4 Gene With Gout in New Zealand Maori and Pacific Men. Arthritis Rheumatol. 2017 07; 69(7):1461-1469. PMID: 28371506.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  6. Mandal AK, Mercado A, Foster A, Zandi-Nejad K, Mount DB. Uricosuric targets of tranilast. Pharmacol Res Perspect. 2017 Apr; 5(2):e00291. PMID: 28357121.
    Citations: 4     Fields:    
  7. Mandal AK, Choi H, Merriman T, Mount DB. Characterization of Coding Variation in the urate Transporter GLUT9, a Key Determinant of Serum Uric Acid: Absence of Gain-of-Function Phenotypes [Abstract] J Am Soc Nephrol. 2016; 27:FR-P0574. View Publication.
  8. Mandal AK, Mount DB. ITM2B inhibits the urate transporter GLUT9: A link between uric acid homeostasis and Neurodegeneration? [Abstract] J Am Soc Nephrol. 2016; 27:FR-P0364. View Publication.
  9. Mandal AK, Mount DB. The molecular physiology of uric acid homeostasis. Annu Rev Physiol. 2015; 77:323-45. PMID: 25422986.
    Citations: 55     Fields:    Translation:HumansAnimalsCells
  10. Mandal AK, Mount, DB. Transcriptional Heterogeneity of the SLC2A9 Gene Encoding the GLUT9 Urate Transporter [Abstract] Am Soc Nephrol. 2014; 25:SA-PO083 . View Publication.
  11. Mandal AK, Mount DB. Transcriptional and Translational Heterogeneity of the SLC2A9 Gene Encoding the GLUT9 Urate Transporter [Abstract] J Am Soc Nephrol. 2013; 24:237A. View Publication.
  12. Mandal AK, Emerling DE, Serafini TA, Mount DB. Tranilast inhibits urate transport mediated by URAT1 and GLUT9 [Abstract] Arthritis Rheum. 2010; 62(10):869. View Publication.
  13. Mercado A, Babilonia E, Gagnon KB, Mandal AK, Delpire E, Mount DB. Terminal threonines in the KCC4 K-Cl cotransporter confer sensitivity to cell volume [Abstract] FASEB J. 2010; 24:609.10.
  14. Li Qinggang, Babilonia Li, Chang M-H, Kwon C, Mandal AK, Mercado A, Romero MF, Mount DB. A role for C-terminal cysteines in oligomerization of the Slc26a6 anion transporter [Abstract] FASEB J. 2010; 24:609.13.
  15. Mandal AK, Jones PB, Bair AM, Christmas P, Miller D, Yamin TT, Wisniewski D, Menke J, Evans JF, Hyman BT, Bacskai B, Chen M, Lee DM, Nikolic B, Soberman RJ. The nuclear membrane organization of leukotriene synthesis. Proc Natl Acad Sci U S A. 2008 Dec 23; 105(51):20434-9. PMID: 19075240.
    Citations: 33     Fields:    Translation:AnimalsCells
  16. Mandal AK, Zhang Z, Kim SJ, Tsai PC, Mukherjee AB. Yin-yang: balancing act of prostaglandins with opposing functions to regulate inflammation. J Immunol. 2005 Nov 15; 175(10):6271-3. PMID: 16272277.
    Citations: 5     Fields:    Translation:AnimalsCells
  17. Mandal AK, Ray R, Zhang Z, Chowdhury B, Pattabiraman N, Mukherjee AB. Uteroglobin inhibits prostaglandin F2alpha receptor-mediated expression of genes critical for the production of pro-inflammatory lipid mediators. J Biol Chem. 2005 Sep 23; 280(38):32897-904. PMID: 16061484.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  18. Mandal AK, Zhang Z, Ray R, Choi MS, Chowdhury B, Pattabiraman N, Mukherjee AB. Uteroglobin represses allergen-induced inflammatory response by blocking PGD2 receptor-mediated functions. J Exp Med. 2004 May 17; 199(10):1317-30. PMID: 15148333.
    Citations: 34     Fields:    Translation:HumansAnimalsCells
  19. Mandal AK, Skoch J, Bacskai BJ, Hyman BT, Christmas P, Miller D, Yamin TT, Xu S, Wisniewski D, Evans JF, Soberman RJ. The membrane organization of leukotriene synthesis. Proc Natl Acad Sci U S A. 2004 Apr 27; 101(17):6587-92. PMID: 15084748.
    Citations: 22     Fields:    Translation:HumansCells
  20. Mandal AK, Zhang Z, Chou JY, Mukherjee AB. Pancreatic phospholipase A2 via its receptor regulates expression of key enzymes of phospholipid and sphingolipid metabolism. FASEB J. 2001 Aug; 15(10):1834-6. PMID: 11481246.
    Citations: 7     Fields:    Translation:AnimalsCells
  21. Mandal AK, Zhang Z, Chou JY, Zimonjic D, Keck CL, Popescu N, Mukherjee AB. Molecular characterization of murine pancreatic phospholipase A(2). DNA Cell Biol. 2001 Mar; 20(3):149-57. PMID: 11313018.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  22. Zhang Z, Mandal AK, Mital A, Popescu N, Zimonjic D, Moser A, Moser H, Mukherjee AB. Human acid ceramidase gene: novel mutations in Farber disease. Mol Genet Metab. 2000 Aug; 70(4):301-9. PMID: 10993717.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  23. Mandal AK, Zhang Z, Chou J, Popescu N, Zimonjic D, Mukherjee AB. FASEB J. Novel sPLA2IB receptor-mediated regulation of mRNA expression for key phospholipid- and sphingolipid- metabolizing enzymes in NIH3T3 cells. 2000; 14:A2.
  24. Yuan CJ, Mandal AK, Zhang Z, Mukherjee AB. Transcriptional regulation of cyclooxygenase-2 gene expression: novel effects of nonsteroidal anti-inflammatory drugs. Cancer Res. 2000 Feb 15; 60(4):1084-91. PMID: 10706128.
    Citations: 7     Fields:    Translation:AnimalsCells
  25. Kundu GC, Zhang Z, Mantile-Selvaggi G, Mandal A, Yuan CJ, Mukherjee AB. Uteroglobin binding proteins: regulation of cellular motility and invasion in normal and cancer cells. Ann N Y Acad Sci. 2000; 923:234-48. PMID: 11193760.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  26. Mandal AK, Zhang Z, Mukherjee AB. Am J Hum Genet. Transcriptional regulation of cyclooxygenase-2 gene expression: novel effects of non-steroidal anti-inflammatory drugs [Abstract]. 1999; 65:A136.
  27. Mandal AK, Zhang Z, Mukherjee AB. FASEB J. Murine pancreatic soluble phospholipase A2: possible modifier role in gastrointestinal cancer. [Abstract]. 1999; 13:A1550.
  28. Mukherjee AB, Kundu GC, Mantile-Selvaggi G, Yuan CJ, Mandal AK, Chattopadhyay S, Zheng F, Pattabiraman N, Zhang Z. Uteroglobin: a novel cytokine? Cell Mol Life Sci. 1999 May; 55(5):771-87. PMID: 10379362.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  29. Zhang Z, Mandal AK, Wang N, Keck CL, Zimonjic DB, Popescu NC, Mukherjee AB. Palmitoyl-protein thioesterase gene expression in the developing mouse brain and retina: implications for early loss of vision in infantile neuronal ceroid lipofuscinosis. Gene. 1999 Apr 29; 231(1-2):203-11. PMID: 10231585.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  30. Zhang Z, Kundu GC, Panda D, Mandal AK, Mantile-Selvaggi G, Peri A, Yuan CJ, Mukherjee AB. Loss of transformed phenotype in cancer cells by overexpression of the uteroglobin gene. Proc Natl Acad Sci U S A. 1999 Mar 30; 96(7):3963-8. PMID: 10097146.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  31. Mukherjee AB, Kundu GC, Mandal AK, Pattabiraman N, Yuan CJ, Zhang Z. Uteroglobin: physiological role in normal glomerular function uncovered by targeted disruption of the uteroglobin gene in mice. Am J Kidney Dis. 1998 Dec; 32(6):1106-20. PMID: 9856533.
    Citations: 4     Fields:    Translation:HumansAnimals
  32. Mandal AK, Zhang Z, Mukherjee AB. Am J Hum Genet. Palmitoyl-protein thioesterase gene expression-pattern in the retina and in brain may explain the pathologic manifestations in INCL. [Abstract]. 1998; 63:A372.
  33. Kundu GC, Mandal AK, Zhang Z, Mantile-Selvaggi G, Mukherjee AB. Uteroglobin (UG) suppresses extracellular matrix invasion by normal and cancer cells that express the high affinity UG-binding proteins. J Biol Chem. 1998 Aug 28; 273(35):22819-24. PMID: 9712916.
    Citations: 4     Fields:    Translation:AnimalsCells
  34. Chatterjee S, Mondal AK, Begum NA, Roychoudhury S, Das J. Ordered cloned DNA map of the genome of Vibrio cholerae 569B and localization of genetic markers. J Bacteriol. 1998 Feb; 180(4):901-8. PMID: 9473045.
    Citations: 6     Fields:    Translation:Cells
  35. Ghosh S, Sadhukhan PC, Ghosh DK, Mandal AK, Chaudhuri J, Mandal A. Studies on the effect of mercury and organomercurial on the growth and nitrogen fixation by mercury-resistant Azotobacter strains. J Appl Bacteriol. 1996; 80(3):319-326.
  36. Mandal AK, Ghosh S. Isolation of a glutamate synthase (GOGAT)-negative, pleiotropically N utilization-defective mutant of Azospirillum brasilense: cloning and partial characterization of GOGAT structural gene. J Bacteriol. 1993 Dec; 175(24):8024-9. PMID: 7902833.
    Citations: 3     Fields:    Translation:Cells
  37. 5(2):e00291-.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.