Harvard Catalyst Profiles

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Zhifang Cao, D.Sc.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Xu W, Rush JS, Graham DB, Cao Z, Xavier RJ. USP15 Deubiquitinates CARD9 to Downregulate C-Type Lectin Receptor-Mediated Signaling. Immunohorizons. 2020 10 22; 4(10):670-678. PMID: 33093067.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  2. Mohanan V, Nakata T, Desch AN, Lévesque C, Boroughs A, Guzman G, Cao Z, Creasey E, Yao J, Boucher G, Charron G, Bhan AK, Schenone M, Carr SA, Reinecker HC, Daly MJ, Rioux JD, Lassen KG, Xavier RJ. C1orf106 is a colitis risk gene that regulates stability of epithelial adherens junctions. Science. 2018 03 09; 359(6380):1161-1166. PMID: 29420262; PMCID: PMC6008784.
    Citations: 42     Fields:    Translation:HumansAnimalsCells
  3. Leshchiner ES, Rush JS, Durney MA, Cao Z, Dancík V, Chittick B, Wu H, Petrone A, Bittker JA, Phillips A, Perez JR, Shamji AF, Kaushik VK, Daly MJ, Graham DB, Schreiber SL, Xavier RJ. Small-molecule inhibitors directly target CARD9 and mimic its protective variant in inflammatory bowel disease. Proc Natl Acad Sci U S A. 2017 10 24; 114(43):11392-11397. PMID: 29073062; PMCID: PMC5664502.
    Citations: 22     Fields:    Translation:HumansCells
  4. Cao Z, Conway KL, Heath RJ, Rush JS, Leshchiner ES, Ramirez-Ortiz ZG, Nedelsky NB, Huang H, Ng A, Gardet A, Cheng SC, Shamji AF, Rioux JD, Wijmenga C, Netea MG, Means TK, Daly MJ, Xavier RJ. Ubiquitin Ligase TRIM62 Regulates CARD9-Mediated Anti-fungal Immunity and Intestinal Inflammation. Immunity. 2015 Oct 20; 43(4):715-26. PMID: 26488816.
    Citations: 48     Fields:    Translation:HumansAnimalsCells
  5. Sokol H, Conway KL, Zhang M, Choi M, Morin B, Cao Z, Villablanca EJ, Li C, Wijmenga C, Yun SH, Shi HN, Xavier RJ. Card9 mediates intestinal epithelial cell restitution, T-helper 17 responses, and control of bacterial infection in mice. Gastroenterology. 2013 Sep; 145(3):591-601.e3. PMID: 23732773; PMCID: PMC3781941.
    Citations: 73     Fields:    Translation:AnimalsCells
  6. Giallourakis CC, Benita Y, Molinie B, Cao Z, Despo O, Pratt HE, Zukerberg LR, Daly MJ, Rioux JD, Xavier RJ. Genome-wide analysis of immune system genes by expressed sequence Tag profiling. J Immunol. 2013 Jun 01; 190(11):5578-87. PMID: 23616578; PMCID: PMC3703829.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  7. Wei SC, Rosenberg IM, Cao Z, Huett AS, Xavier RJ, Podolsky DK. Tribbles 2 (Trib2) is a novel regulator of toll-like receptor 5 signaling. Inflamm Bowel Dis. 2012 May; 18(5):877-88. PMID: 22271508; PMCID: PMC3881418.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  8. Benita Y, Cao Z, Giallourakis C, Li C, Gardet A, Xavier RJ. Gene enrichment profiles reveal T-cell development, differentiation, and lineage-specific transcription factors including ZBTB25 as a novel NF-AT repressor. Blood. 2010 Jul 01; 115(26):5376-84. PMID: 20410506; PMCID: PMC2902135.
    Citations: 79     Fields:    Translation:HumansCells
  9. Huett A, Ng A, Cao Z, Kuballa P, Komatsu M, Daly MJ, Podolsky DK, Xavier RJ. A novel hybrid yeast-human network analysis reveals an essential role for FNBP1L in antibacterial autophagy. J Immunol. 2009 Apr 15; 182(8):4917-30. PMID: 19342671; PMCID: PMC2752416.
    Citations: 35     Fields:    Translation:HumansAnimalsCells
  10. Medoff BD, Landry AL, Wittbold KA, Sandall BP, Derby MC, Cao Z, Adams JC, Xavier RJ. CARMA3 mediates lysophosphatidic acid-stimulated cytokine secretion by bronchial epithelial cells. Am J Respir Cell Mol Biol. 2009 Mar; 40(3):286-94. PMID: 18757306.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  11. Cao Z, Huett A, Kuballa P, Giallourakis C, Xavier RJ. DLG1 is an anchor for the E3 ligase MARCH2 at sites of cell-cell contact. Cell Signal. 2008 Jan; 20(1):73-82. PMID: 17980554.
    Citations: 14     Fields:    Translation:HumansCells
  12. Giallourakis C, Cao Z, Green T, Wachtel H, Xie X, Lopez-Illasaca M, Daly M, Rioux J, Xavier R. A molecular-properties-based approach to understanding PDZ domain proteins and PDZ ligands. Genome Res. 2006 Aug; 16(8):1056-72. PMID: 16825666; PMCID: PMC1524865.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  13. Ishiguro K, Green T, Rapley J, Wachtel H, Giallourakis C, Landry A, Cao Z, Lu N, Takafumi A, Goto H, Daly MJ, Xavier RJ. Ca2+/calmodulin-dependent protein kinase II is a modulator of CARMA1-mediated NF-kappaB activation. Mol Cell Biol. 2006 Jul; 26(14):5497-508. PMID: 16809782; PMCID: PMC1592706.
    Citations: 52     Fields:    Translation:HumansCells
  14. Ishiguro K, Cao Z, Ilasca ML, Ando T, Xavier R. Wave2 activates serum response element via its VCA region and functions downstream of Rac. Exp Cell Res. 2004 Dec 10; 301(2):331-7. PMID: 15530867.
    Citations: 1     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.