Harvard Catalyst Profiles

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Hanne M. Kooy, Ph.D.

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Research
research activities and funding
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  1. U19CA021239 (HONG, THEODORE S) Apr 1, 1997 - Aug 31, 2020
    NIH
    Improving the Clinical Effectiveness and Understanding of the Biophysical Basis
    Role: Co-Principal Investigator
  2. P01CA021239 (DELANEY, THOMAS F) Aug 1, 1985 - Sep 24, 2014
    NIH
    PROTON RADIATION THERAPY RESEARCH
    Role: Co-Principal Investigator

Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Ioakeim-Ioannidou M, Tejada A, Urell T, Depauw N, Kooy H, Adams J, Fullerton B, Kelly H, MacDonald SM. Late Radiation-Induced Carotid Artery Stenosis and Stroke in Pediatric Patient Treated With Proton Radiation Therapy for Skull-Base Chordoma. Pract Radiat Oncol. 2023 Jan 12. PMID: 36641091.
    Citations:    Fields:    
  2. Depauw N, Kooy H, Winey B, Clasie B. Pencil beam scanning dose calibration at reduced source-to-axis distance. Med Phys. 2022 Aug; 49(8):5476-5482. PMID: 35526213.
    Citations:    Fields:    
  3. Depauw N, Kooy HM, Daartz J, Bussière M, Batin E, Madden T, Williams M, Schueman J, Clasie BM. Implementation of apertures in a proton pencil-beam dose algorithm. Biomed Phys Eng Express. 2022 02 25; 8(2). PMID: 35158343.
    Citations:    Fields:    Translation:Humans
  4. Shin J, Kooy HM, Paganetti H, Clasie B. DICOM-RT Ion interface to utilize MC simulations in routine clinical workflow for proton pencil beam radiotherapy. Phys Med. 2020 06; 74:1-10. PMID: 32388464.
    Citations: 1     Fields:    Translation:Humans
  5. Depauw N, Keyriläinen J, Suilamo S, Warner L, Bzdusek K, Olsen C, Kooy H. MRI-based IMPT planning for prostate cancer. Radiother Oncol. 2020 03; 144:79-85. PMID: 31734604.
    Citations: 4     Fields:    Translation:Humans
  6. Hamming-Vrieze O, Depauw N, Craft DL, Chan AW, Rasch CRN, Verheij M, Sonke JJ, Kooy HM. Impact of setup and range uncertainties on TCP and NTCP following VMAT or IMPT of oropharyngeal cancer patients. Phys Med Biol. 2019 04 23; 64(9):095001. PMID: 30921775.
    Citations: 1     Fields:    Translation:Humans
  7. Kraan AC, Depauw N, Clasie B, Madden T, Kooy HM. Impact of spot size variations on dose in scanned proton beam therapy. Phys Med. 2019 Jan; 57:58-64. PMID: 30738532.
    Citations: 4     Fields:    Translation:Humans
  8. Lin Y, Bentefour H, Flanz J, Kooy H, Clasie B. Design of a QA method to characterize submillimeter-sized PBS beam properties using a 2D ionization chamber array. Phys Med Biol. 2018 05 15; 63(10):105007. PMID: 29644984.
    Citations:    Fields:    Translation:Humans
  9. Haas-Kogan D, Indelicato D, Paganetti H, Esiashvili N, Mahajan A, Yock T, Flampouri S, MacDonald S, Fouladi M, Stephen K, Kalapurakal J, Terezakis S, Kooy H, Grosshans D, Makrigiorgos M, Mishra K, Poussaint TY, Cohen K, Fitzgerald T, Gondi V, Liu A, Michalski J, Mirkovic D, Mohan R, Perkins S, Wong K, Vikram B, Buchsbaum J, Kun L. National Cancer Institute Workshop on Proton Therapy for Children: Considerations Regarding Brainstem Injury. Int J Radiat Oncol Biol Phys. 2018 05 01; 101(1):152-168. PMID: 29619963; PMCID: PMC5903576.
    Citations: 43     Fields:    Translation:HumansCellsPHPublic Health
  10. Kraan AC, Depauw N, Clasie B, Giunta M, Madden T, Kooy HM. Effects of spot parameters in pencil beam scanning treatment planning. Med Phys. 2018 Jan; 45(1):60-73. PMID: 29148575.
    Citations: 4     Fields:    
  11. Gentile MS, Yeap BY, Paganetti H, Goebel CP, Gaudet DE, Gallotto SL, Weyman EA, Morgan ML, MacDonald SM, Giantsoudi D, Adams J, Tarbell NJ, Kooy H, Yock TI. Brainstem Injury in Pediatric Patients With Posterior Fossa Tumors Treated With Proton Beam Therapy and Associated Dosimetric Factors. Int J Radiat Oncol Biol Phys. 2018 03 01; 100(3):719-729. PMID: 29413284.
    Citations: 17     Fields:    Translation:HumansPHPublic Health
  12. Tran LT, Chartier L, Bolst D, Pogossov A, Guatelli S, Petasecca M, Lerch MLF, Prokopovich DA, Reinhard MI, Clasie B, Depauw N, Kooy H, Flanz JB, McNamara A, Paganetti H, Beltran C, Furutani K, Perevertaylo VL, Jackson M, Rosenfeld AB. Characterization of proton pencil beam scanning and passive beam using a high spatial resolution solid-state microdosimeter. Med Phys. 2017 Nov; 44(11):6085-6095. PMID: 28887837.
    Citations: 6     Fields:    
  13. Kraan AC, Depauw N, Clasie B, Giunta M, Madden T, Kooy HM. Impact of spot charge inaccuracies in IMPT treatments. Med Phys. 2017 Aug; 44(8):3923-3931. PMID: 28569997.
    Citations: 1     Fields:    Translation:Humans
  14. Giantsoudi D, Seco J, Eaton BR, Simeone FJ, Kooy H, Yock TI, Tarbell NJ, DeLaney TF, Adams J, Paganetti H, MacDonald SM. Evaluating Intensity Modulated Proton Therapy Relative to Passive Scattering Proton Therapy for Increased Vertebral Column Sparing in Craniospinal Irradiation in Growing Pediatric Patients. Int J Radiat Oncol Biol Phys. 2017 05 01; 98(1):37-46. PMID: 28587051; PMCID: PMC5466873.
    Citations: 11     Fields:    Translation:HumansCells
  15. Lin Y, Kooy H, Craft D, Depauw N, Flanz J, Clasie B. A Greedy reassignment algorithm for the PBS minimum monitor unit constraint. Phys Med Biol. 2016 06 21; 61(12):4665-78. PMID: 27245098.
    Citations: 4     Fields:    Translation:Humans
  16. Lin Y, Kooy H, Craft D, Depauw N, Flanz J, Clasie B. TH-CD-209-01: A Greedy Reassignment Algorithm for the PBS Minimum Monitor Unit Constraint. Med Phys. 2016 Jun; 43(6):3885-3886. PMID: 28046343.
    Citations:    
  17. Shin J, Jee K, Clasie B, Depauw N, Madden T, Sharp G, Paganetti H, Kooy H. SU-G-TeP4-04: An Automated Monte Carlo Based QA Framework for Pencil Beam Scanning Treatments. Med Phys. 2016 Jun; 43(6):3685. PMID: 28047026.
    Citations:    
  18. Moteabbed M, Yock TI, Depauw N, Madden TM, Kooy HM, Paganetti H. Impact of Spot Size and Beam-Shaping Devices on the Treatment Plan Quality for Pencil Beam Scanning Proton Therapy. Int J Radiat Oncol Biol Phys. 2016 May 01; 95(1):190-198. PMID: 27084640; PMCID: PMC4834139.
    Citations: 25     Fields:    Translation:HumansPHPublic Health
  19. Clasie BM, Kooy HM, Flanz JB. PBS machine interlocks using EWMA. Phys Med Biol. 2016 Jan 07; 61(1):400-12. PMID: 26674990.
    Citations: 1     Fields:    Translation:Humans
  20. Moteabbed M, Depauw N, Kooy H, Yock T, Paganetti H. SU-F-BRD-12: When Does Pencil Beam Scanning Become Superior to Passive Scattered Proton Therapy for Pediatric Head and Neck Cancers? Med Phys. 2015 Jun; 42(6):3528. PMID: 26128492.
    Citations:    
  21. Kooy HM, Grassberger C. Intensity modulated proton therapy. Br J Radiol. 2015 Jul; 88(1051):20150195. PMID: 26084352; PMCID: PMC4628542.
    Citations: 17     Fields:    Translation:Humans
  22. van de Water S, Kooy HM, Heijmen BJ, Hoogeman MS. Shortening delivery times of intensity modulated proton therapy by reducing proton energy layers during treatment plan optimization. Int J Radiat Oncol Biol Phys. 2015 Jun 01; 92(2):460-8. PMID: 25823447.
    Citations: 15     Fields:    Translation:Humans
  23. Depauw N, Batin E, Daartz J, Rosenfeld A, Adams J, Kooy H, MacDonald S, Lu HM. A novel approach to postmastectomy radiation therapy using scanned proton beams. Int J Radiat Oncol Biol Phys. 2015 Feb 01; 91(2):427-34. PMID: 25636765.
    Citations: 20     Fields:    Translation:Humans
  24. Deisher A, Whitaker T, Kooy H, Trofimov A, Kruse J. SU-E-T-441: Comparison of Dose Distributions for Spot-Scanned Pencil-Beam and Scattered-Beam Proton Treatments of Ocular Tumors. Med Phys. 2014 Jun; 41(6):327. PMID: 28036933.
    Citations:    
  25. Kraan AC, van de Water S, Teguh DN, Al-Mamgani A, Madden T, Kooy HM, Heijmen BJ, Hoogeman MS. Dose uncertainties in IMPT for oropharyngeal cancer in the presence of anatomical, range, and setup errors. Int J Radiat Oncol Biol Phys. 2013 Dec 01; 87(5):888-96. PMID: 24351409.
    Citations: 27     Fields:    Translation:Humans
  26. Petit S, Seco J, Kooy H. Increasing maximum tumor dose to manage range uncertainties in IMPT treatment planning. Phys Med Biol. 2013 Oct 21; 58(20):7329-41. PMID: 24077105.
    Citations: 1     Fields:    Translation:Humans
  27. van de Water S, Kraan AC, Breedveld S, Schillemans W, Teguh DN, Kooy HM, Madden TM, Heijmen BJ, Hoogeman MS. Improved efficiency of multi-criteria IMPT treatment planning using iterative resampling of randomly placed pencil beams. Phys Med Biol. 2013 Oct 07; 58(19):6969-83. PMID: 24029721.
    Citations: 10     Fields:    Translation:Humans
  28. Seco J, Gu G, Marcelos T, Kooy H, Willers H. Proton arc reduces range uncertainty effects and improves conformality compared with photon volumetric modulated arc therapy in stereotactic body radiation therapy for non-small cell lung cancer. Int J Radiat Oncol Biol Phys. 2013 Sep 01; 87(1):188-94. PMID: 23920395.
    Citations: 19     Fields:    Translation:HumansPHPublic Health
  29. Kruse J, Kooy H, Dong L. WE-C-500-01: Imaging Needs for Proton Therapy. Med Phys. 2013 Jun; 40(6Part28):477. PMID: 28519955.
    Citations:    
  30. Jimenez RB, Goma C, Nyamwanda J, Kooy HM, Halabi T, Napolitano BN, McBride SM, Taghian AG, Lu HM, MacDonald SM. Intensity modulated proton therapy for postmastectomy radiation of bilateral implant reconstructed breasts: a treatment planning study. Radiother Oncol. 2013 May; 107(2):213-7. PMID: 23647751.
    Citations: 21     Fields:    Translation:Humans
  31. MacDonald SM, Jimenez R, Paetzold P, Adams J, Beatty J, DeLaney TF, Kooy H, Taghian AG, Lu HM. Proton radiotherapy for chest wall and regional lymphatic radiation; dose comparisons and treatment delivery. Radiat Oncol. 2013 Mar 24; 8:71. PMID: 23521809.
    Citations: 27     Fields:    Translation:Humans
  32. MacDonald SM, Patel SA, Hickey S, Specht M, Isakoff SJ, Gadd M, Smith BL, Yeap BY, Adams J, Delaney TF, Kooy H, Lu HM, Taghian AG. Proton therapy for breast cancer after mastectomy: early outcomes of a prospective clinical trial. Int J Radiat Oncol Biol Phys. 2013 Jul 01; 86(3):484-90. PMID: 23523326.
    Citations: 47     Fields:    Translation:HumansCTClinical Trials
  33. Clasie BM, Flanz JB, Kooy HM. Interpolation of tabulated proton Bragg peaks. Phys Med Biol. 2012 Nov 07; 57(21):N405-9. PMID: 23073269.
    Citations:    Fields:    
  34. Clasie BM, Sharp GC, Seco J, Flanz JB, Kooy HM. Numerical solutions of the ?-index in two and three dimensions. Phys Med Biol. 2012 Nov 07; 57(21):6981-97. PMID: 23044713.
    Citations: 10     Fields:    
  35. Butterworth KT, McGarry CK, Clasie B, Carabe-Fernandez A, Schuemann J, Depauw N, Tang S, McMahon SJ, Schettino G, O'Sullivan JM, Lu HM, Kooy H, Paganetti H, Hounsell AR, Held KD, Prise KM. Relative biological effectiveness (RBE) and out-of-field cell survival responses to passive scattering and pencil beam scanning proton beam deliveries. Phys Med Biol. 2012 Oct 21; 57(20):6671-80. PMID: 23022765.
    Citations: 5     Fields:    Translation:HumansCells
  36. Dowdell S, Clasie B, Depauw N, Metcalfe P, Rosenfeld A, Kooy H, Flanz J, Paganetti H. MO-F-213AB-03: Potential Reduction in Out-Of-Field Dose in Pencil Beam Scanning Proton Therapy Through Use of a Patient-Specific Aperture. Med Phys. 2012 Jun; 39(6Part21):3872. PMID: 28518261.
    Citations:    Fields:    
  37. Dowdell SJ, Clasie B, Depauw N, Metcalfe P, Rosenfeld AB, Kooy HM, Flanz JB, Paganetti H. Monte Carlo study of the potential reduction in out-of-field dose using a patient-specific aperture in pencil beam scanning proton therapy. Phys Med Biol. 2012 May 21; 57(10):2829-42. PMID: 22513726.
    Citations: 19     Fields:    Translation:Humans
  38. Clasie B, Depauw N, Fransen M, Gomà C, Panahandeh HR, Seco J, Flanz JB, Kooy HM. Golden beam data for proton pencil-beam scanning. Phys Med Biol. 2012 Mar 07; 57(5):1147-58. PMID: 22330090.
    Citations: 18     Fields:    Translation:Humans
  39. Chen W, Unkelbach J, Trofimov A, Madden T, Kooy H, Bortfeld T, Craft D. Including robustness in multi-criteria optimization for intensity-modulated proton therapy. Phys Med Biol. 2012 Feb 07; 57(3):591-608. PMID: 22222720.
    Citations: 44     Fields:    Translation:Humans
  40. Hattangadi JA, Rombi B, Yock TI, Broussard G, Friedmann AM, Huang M, Chen YL, Lu HM, Kooy H, MacDonald SM. Proton radiotherapy for high-risk pediatric neuroblastoma: early outcomes and dose comparison. Int J Radiat Oncol Biol Phys. 2012 Jul 01; 83(3):1015-22. PMID: 22138463.
    Citations: 21     Fields:    Translation:Humans
  41. Chen W, Craft D, Madden TM, Zhang K, Kooy HM, Herman GT. A fast optimization algorithm for multicriteria intensity modulated proton therapy planning. Med Phys. 2010 Sep; 37(9):4938-45. PMID: 20964213.
    Citations: 10     Fields:    Translation:Humans
  42. Paganetti H, Kooy H. Proton radiation in the management of localized cancer. Expert Rev Med Devices. 2010 Mar; 7(2):275-85. PMID: 20214431.
    Citations: 3     Fields:    Translation:Humans
  43. Kooy HM, Clasie BM, Lu HM, Madden TM, Bentefour H, Depauw N, Adams JA, Trofimov AV, Demaret D, Delaney TF, Flanz JB. A case study in proton pencil-beam scanning delivery. Int J Radiat Oncol Biol Phys. 2010 Feb 01; 76(2):624-30. PMID: 20117294.
    Citations: 26     Fields:    Translation:Humans
  44. Clasie B, Wroe A, Kooy H, Depauw N, Flanz J, Paganetti H, Rosenfeld A. Assessment of out-of-field absorbed dose and equivalent dose in proton fields. Med Phys. 2010 Jan; 37(1):311-21. PMID: 20175494.
    Citations: 17     Fields:    Translation:Humans
  45. Engelsman M, Lu HM, Herrup D, Bussiere M, Kooy HM. Commissioning a passive-scattering proton therapy nozzle for accurate SOBP delivery. Med Phys. 2009 Jun; 36(6):2172-80. PMID: 19610306.
    Citations: 8     Fields:    
  46. Daartz J, Bangert M, Bussière MR, Engelsman M, Kooy HM. Characterization of a mini-multileaf collimator in a proton beamline. Med Phys. 2009 May; 36(5):1886-94. PMID: 19544808.
    Citations: 7     Fields:    
  47. Wroe A, Clasie B, Kooy H, Flanz J, Schulte R, Rosenfeld A. Out-of-field dose equivalents delivered by passively scattered therapeutic proton beams for clinically relevant field configurations. Int J Radiat Oncol Biol Phys. 2009 Jan 01; 73(1):306-13. PMID: 19100924.
    Citations: 6     Fields:    Translation:Humans
  48. Suit H, Kooy H, Trofimov A, Farr J, Munzenrider J, DeLaney T, Loeffler J, Clasie B, Safai S, Paganetti H. Should positive phase III clinical trial data be required before proton beam therapy is more widely adopted? No. Radiother Oncol. 2008 Feb; 86(2):148-53. PMID: 18237800.
    Citations: 23     Fields:    Translation:HumansPHPublic Health
  49. Lu HM, Brett R, Engelsman M, Slopsema R, Kooy H, Flanz J. Sensitivities in the production of spread-out Bragg peak dose distributions by passive scattering with beam current modulation. Med Phys. 2007 Oct; 34(10):3844-53. PMID: 17985630.
    Citations: 7     Fields:    
  50. Lu HM, Brett R, Sharp G, Safai S, Jiang S, Flanz J, Kooy H. A respiratory-gated treatment system for proton therapy. Med Phys. 2007 Aug; 34(8):3273-8. PMID: 17879790.
    Citations: 11     Fields:    Translation:Humans
  51. Slopsema RL, Kooy HM. Incorporation of the aperture thickness in proton pencil-beam dose calculations. Phys Med Biol. 2006 Nov 07; 51(21):5441-53. PMID: 17047262.
    Citations: 3     Fields:    Translation:Humans
  52. Lu HM, Kooy H. Optimization of current modulation function for proton spread-out Bragg peak fields. Med Phys. 2006 May; 33(5):1281-7. PMID: 16752563.
    Citations: 13     Fields:    
  53. Engelsman M, Rietzel E, Kooy HM. Four-dimensional proton treatment planning for lung tumors. Int J Radiat Oncol Biol Phys. 2006 Apr 01; 64(5):1589-95. PMID: 16580508.
    Citations: 48     Fields:    Translation:HumansPHPublic Health
  54. Kooy HM, Rosenthal SJ, Engelsman M, Mazal A, Slopsema RL, Paganetti H, Flanz JB. The prediction of output factors for spread-out proton Bragg peak fields in clinical practice. Phys Med Biol. 2005 Dec 21; 50(24):5847-56. PMID: 16333159.
    Citations: 14     Fields:    Translation:Humans
  55. Engelsman M, Kooy HM. Target volume dose considerations in proton beam treatment planning for lung tumors. Med Phys. 2005 Dec; 32(12):3549-57. PMID: 16475753.
    Citations: 23     Fields:    Translation:Humans
  56. Engelsman M, Rosenthal SJ, Michaud SL, Adams JA, Schneider RJ, Bradley SG, Flanz JB, Kooy HM. Intra- and interfractional patient motion for a variety of immobilization devices. Med Phys. 2005 Nov; 32(11):3468-74. PMID: 16372417.
    Citations: 23     Fields:    Translation:Humans
  57. Levin WP, Kooy H, Loeffler JS, DeLaney TF. Proton beam therapy. Br J Cancer. 2005 Oct 17; 93(8):849-54. PMID: 16189526; PMCID: PMC2361650.
    Citations: 68     Fields:    Translation:HumansPHPublic Health
  58. Chan AW, Black P, Ojemann RG, Barker FG, Kooy HM, Lopes VV, McKenna MJ, Shrieve DC, Martuza RL, Loeffler JS. Stereotactic radiotherapy for vestibular schwannomas: favorable outcome with minimal toxicity. Neurosurgery. 2005 Jul; 57(1):60-70; discussion 60-70. PMID: 15987541.
    Citations: 13     Fields:    Translation:HumansCTClinical Trials
  59. Marcus KJ, Goumnerova L, Billett AL, Lavally B, Scott RM, Bishop K, Xu R, Young Poussaint T, Kieran M, Kooy H, Pomeroy SL, Tarbell NJ. Stereotactic radiotherapy for localized low-grade gliomas in children: final results of a prospective trial. Int J Radiat Oncol Biol Phys. 2005 Feb 01; 61(2):374-9. PMID: 15667955.
    Citations: 32     Fields:    Translation:Humans
  60. Paganetti H, Jiang H, Lee SY, Kooy HM. Accurate Monte Carlo simulations for nozzle design, commissioning and quality assurance for a proton radiation therapy facility. Med Phys. 2004 Jul; 31(7):2107-18. PMID: 15305464.
    Citations: 47     Fields:    
  61. St Clair WH, Adams JA, Bues M, Fullerton BC, La Shell S, Kooy HM, Loeffler JS, Tarbell NJ. Advantage of protons compared to conventional X-ray or IMRT in the treatment of a pediatric patient with medulloblastoma. Int J Radiat Oncol Biol Phys. 2004 Mar 01; 58(3):727-34. PMID: 14967427.
    Citations: 101     Fields:    Translation:Humans
  62. D'amico AV, Tempany CM, Schultz D, Cormack RA, Hurwitz M, Beard C, Albert M, Kooy H, Jolesz F, Richie JP. Comparing PSA outcome after radical prostatectomy or magnetic resonance imaging-guided partial prostatic irradiation in select patients with clinically localized adenocarcinoma of the prostate. Urology. 2003 Dec; 62(6):1063-7. PMID: 14665356.
    Citations: 15     Fields:    Translation:Humans
  63. Kooy HM, Schaefer M, Rosenthal S, Bortfeld T. Monitor unit calculations for range-modulated spread-out Bragg peak fields. Phys Med Biol. 2003 Sep 07; 48(17):2797-808. PMID: 14516102.
    Citations: 15     Fields:    Translation:Cells
  64. Albert M, Tempany CM, Schultz D, Chen MH, Cormack RA, Kumar S, Hurwitz MD, Beard C, Tuncali K, O'Leary M, Topulos GP, Valentine K, Lopes L, Kanan A, Kacher D, Rosato J, Kooy H, Jolesz F, Carr-Locke DL, Richie JP, D'Amico AV. Late genitourinary and gastrointestinal toxicity after magnetic resonance image-guided prostate brachytherapy with or without neoadjuvant external beam radiation therapy. Cancer. 2003 Sep 01; 98(5):949-54. PMID: 12942561.
    Citations: 23     Fields:    Translation:HumansPHPublic Health
  65. Mechalakos JG, Mageras GS, Zelefsky MJ, Lyass O, van Herk M, Kooy HM, Leibel SA, Ling CC. Time trends in organ position and volume in patients receiving prostate three-dimensional conformal radiotherapy. Radiother Oncol. 2002 Mar; 62(3):261-5. PMID: 12175556.
    Citations: 1     Fields:    Translation:Humans
  66. Zissiadis Y, Dutton S, Kieran M, Goumnerova L, Scott RM, Kooy HM, Tarbell NJ. Stereotactic radiotherapy for pediatric intracranial germ cell tumors. Int J Radiat Oncol Biol Phys. 2001 Sep 01; 51(1):108-12. PMID: 11516859.
    Citations: 3     Fields:    Translation:Humans
  67. Hodgson DC, Goumnerova LC, Loeffler JS, Dutton S, Black PM, Alexander E, Xu R, Kooy H, Silver B, Tarbell NJ. Radiosurgery in the management of pediatric brain tumors. Int J Radiat Oncol Biol Phys. 2001 Jul 15; 50(4):929-35. PMID: 11429220.
    Citations: 25     Fields:    Translation:Humans
  68. Kooy HM, Cormack RA, Mathiowitz G, Tempany C, D'Amico AV. A software system for interventional magnetic resonance image-guided prostate brachytherapy. Comput Aided Surg. 2000; 5(6):401-13. PMID: 11295853.
    Citations: 4     Fields:    Translation:Humans
  69. Cormack RA, Kooy H, Tempany CM, D'Amico AV. A clinical method for real-time dosimetric guidance of transperineal 125I prostate implants using interventional magnetic resonance imaging. Int J Radiat Oncol Biol Phys. 2000 Jan 01; 46(1):207-14. PMID: 10656394.
    Citations: 9     Fields:    Translation:HumansCTClinical Trials
  70. Loeffler JS, Kooy HM, Tarbell NJ. The emergence of conformal radiotherapy: special implications for pediatric neuro-oncology. Int J Radiat Oncol Biol Phys. 1999 May 01; 44(2):237-8. PMID: 10928843.
    Citations: 1     Fields:    Translation:Humans
  71. Zelefsky MJ, Crean D, Mageras GS, Lyass O, Happersett L, Ling CC, Leibel SA, Fuks Z, Bull S, Kooy HM, van Herk M, Kutcher GJ. Quantification and predictors of prostate position variability in 50 patients evaluated with multiple CT scans during conformal radiotherapy. Radiother Oncol. 1999 Feb; 50(2):225-34. PMID: 10368047.
    Citations: 43     Fields:    Translation:Humans
  72. Mageras GS, Fuks Z, Leibel SA, Ling CC, Zelefsky MJ, Kooy HM, van Herk M, Kutcher GJ. Computerized design of target margins for treatment uncertainties in conformal radiotherapy. Int J Radiat Oncol Biol Phys. 1999 Jan 15; 43(2):437-45. PMID: 10030273.
    Citations: 9     Fields:    Translation:Humans
  73. Shrieve DC, Alexander E, Black PM, Wen PY, Fine HA, Kooy HM, Loeffler JS. Treatment of patients with primary glioblastoma multiforme with standard postoperative radiotherapy and radiosurgical boost: prognostic factors and long-term outcome. J Neurosurg. 1999 Jan; 90(1):72-7. PMID: 10413158.
    Citations: 54     Fields:    Translation:Humans
  74. D'Amico AV, Cormack R, Tempany CM, Kumar S, Topulos G, Kooy HM, Coleman CN. Real-time magnetic resonance image-guided interstitial brachytherapy in the treatment of select patients with clinically localized prostate cancer. Int J Radiat Oncol Biol Phys. 1998 Oct 01; 42(3):507-15. PMID: 9806508.
    Citations: 36     Fields:    Translation:Humans
  75. Cormack RA, Kooy HM, Bellerive MR, Loeffler JS, Petersen RA, Tarbell NJ. A stereotactic radiation therapy device for retinoblastoma using a noncircular collimator and intensity filter. Med Phys. 1998 Aug; 25(8):1438-42. PMID: 9725131.
    Citations: 3     Fields:    Translation:Humans
  76. Bellerive MR, Kooy HM, Loeffler JS. Linac radiosurgery at the Joint Center for Radiation Therapy. Med Dosim. 1998; 23(3):187-99. PMID: 9783272.
    Citations:    Fields:    Translation:Humans
  77. Lu HM, Kooy HM, Leber ZH, Ledoux RJ. Optimized beam planning for linear accelerator-based stereotactic radiosurgery. Int J Radiat Oncol Biol Phys. 1997 Dec 01; 39(5):1183-9. PMID: 9392561.
    Citations: 1     Fields:    Translation:Humans
  78. Hacker FL, Kooy HM, Bellerive MR, Killoran JH, Leber ZH, Shrieve DC, Tarbell NJ, Loeffler JS. Beam shaping for conformal fractionated stereotactic radiotherapy: a modeling study. Int J Radiat Oncol Biol Phys. 1997 Jul 15; 38(5):1113-21. PMID: 9276379.
    Citations:    Fields:    Translation:Humans
  79. Shiu AS, Kooy HM, Ewton JR, Tung SS, Wong J, Antes K, Maor MH. Comparison of miniature multileaf collimation (MMLC) with circular collimation for stereotactic treatment. Int J Radiat Oncol Biol Phys. 1997 Feb 01; 37(3):679-88. PMID: 9112467.
    Citations: 13     Fields:    Translation:Humans
  80. Killoran JH, Kooy HM, Gladstone DJ, Welte FJ, Beard CJ. A numerical simulation of organ motion and daily setup uncertainties: implications for radiation therapy. Int J Radiat Oncol Biol Phys. 1997 Jan 01; 37(1):213-21. PMID: 9054898.
    Citations: 8     Fields:    Translation:Humans
  81. Varlotto JM, Shrieve DC, Alexander E, Kooy HM, Black PM, Loeffler JS. Fractionated stereotactic radiotherapy for the treatment of acoustic neuromas: preliminary results. Int J Radiat Oncol Biol Phys. 1996 Aug 01; 36(1):141-5. PMID: 8823269.
    Citations: 6     Fields:    Translation:Humans
  82. Shrieve DC, Kooy HM, Tarbell NJ, Loeffler JS. Fractionated stereotactic radiotherapy. Important Adv Oncol. 1996; 205-24. PMID: 8791137.
    Citations: 1     Fields:    Translation:Humans
  83. Alexander E, Kooy HM, van Herk M, Schwartz M, Barnes PD, Tarbell N, Mulkern RV, Holupka EJ, Loeffler JS. Magnetic resonance image-directed stereotactic neurosurgery: use of image fusion with computerized tomography to enhance spatial accuracy. J Neurosurg. 1995 Aug; 83(2):271-6. PMID: 7616273.
    Citations: 14     Fields:    Translation:Humans
  84. Loeffler JS, Shrieve DC, Wen PY, Fine HA, Kooy HM, Addesa AE, Black PM, Alexander E. Radiosurgery for Intracranial Malignancies. Semin Radiat Oncol. 1995 Jul; 5(3):225-234. PMID: 10717146.
    Citations: 3     Fields:    
  85. Shrieve DC, Alexander E, Wen PY, Fine HA, Kooy HM, Black PM, Loeffler JS. Comparison of stereotactic radiosurgery and brachytherapy in the treatment of recurrent glioblastoma multiforme. Neurosurgery. 1995 Feb; 36(2):275-82; discussion 282-4. PMID: 7731507.
    Citations: 76     Fields:    Translation:HumansPHPublic Health
  86. Alexander E, Moriarty TM, Davis RB, Wen PY, Fine HA, Black PM, Kooy HM, Loeffler JS. Stereotactic radiosurgery for the definitive, noninvasive treatment of brain metastases. J Natl Cancer Inst. 1995 Jan 04; 87(1):34-40. PMID: 7666461.
    Citations: 87     Fields:    Translation:Humans
  87. Kooy HM, Dunbar SF, Tarbell NJ, Mannarino E, Ferarro N, Shusterman S, Bellerive M, Finn L, McDonough CV, Loeffler JS. Adaptation and verification of the relocatable Gill-Thomas-Cosman frame in stereotactic radiotherapy. Int J Radiat Oncol Biol Phys. 1994 Oct 15; 30(3):685-91. PMID: 7928501.
    Citations: 21     Fields:    Translation:Humans
  88. Dunbar SF, Tarbell NJ, Kooy HM, Alexander E, Black PM, Barnes PD, Goumnerova L, Scott RM, Pomeroy SL, La Vally B, et al. Stereotactic radiotherapy for pediatric and adult brain tumors: preliminary report. Int J Radiat Oncol Biol Phys. 1994 Oct 15; 30(3):531-9. PMID: 7928483.
    Citations: 9     Fields:    Translation:HumansCTClinical Trials
  89. Bodis S, Alexander E, Kooy H, Loeffler JS. The prevention of radiosurgery-induced nausea and vomiting by ondansetron: evidence of a direct effect on the central nervous system chemoreceptor trigger zone. Surg Neurol. 1994 Sep; 42(3):249-52. PMID: 7940114.
    Citations: 6     Fields:    Translation:HumansCTClinical Trials
  90. van Herk M, Kooy HM. Automatic three-dimensional correlation of CT-CT, CT-MRI, and CT-SPECT using chamfer matching. Med Phys. 1994 Jul; 21(7):1163-78. PMID: 7968850.
    Citations: 28     Fields:    Translation:Humans
  91. Hughes-Davies L, Mannarino E, Alexander E, Kooy H, Loeffler JS. Technical modifications required to treat cervical chemodactomas with stereotactic radiosurgery. Surg Neurol. 1994 May; 41(5):418-20. PMID: 8009419.
    Citations: 1     Fields:    Translation:Humans
  92. Kooy HM, van Herk M, Barnes PD, Alexander E, Dunbar SF, Tarbell NJ, Mulkern RV, Holupka EJ, Loeffler JS. Image fusion for stereotactic radiotherapy and radiosurgery treatment planning. Int J Radiat Oncol Biol Phys. 1994 Mar 30; 28(5):1229-34. PMID: 8175410.
    Citations: 10     Fields:    Translation:Humans
  93. Schell MC, Kooy H. Stereotactic radiosurgery quality improvement: interdepartmental collaboration. Int J Radiat Oncol Biol Phys. 1994 Jan 15; 28(2):551-2. PMID: 8276676.
    Citations: 1     Fields:    Translation:Humans
  94. Shrieve DC, Tarbell NJ, Alexander E, Kooy HM, Black PM, Dunbar S, Loeffler JS. Stereotactic radiotherapy: a technique for dose optimization and escalation for intracranial tumors. Acta Neurochir Suppl. 1994; 62:118-23. PMID: 7717128.
    Citations: 4     Fields:    Translation:Humans
  95. Tishler RB, Loeffler JS, Lunsford LD, Duma C, Alexander E, Kooy HM, Flickinger JC. Tolerance of cranial nerves of the cavernous sinus to radiosurgery. Int J Radiat Oncol Biol Phys. 1993 Sep 30; 27(2):215-21. PMID: 8407394.
    Citations: 69     Fields:    Translation:Humans
  96. Kooy HM, Nedzi LA, Alexander E, Loeffler JS, Ledoux RJ. Dose-volume histogram computations for small intracranial volumes. Med Phys. 1993 May-Jun; 20(3):755-60. PMID: 8350832.
    Citations: 1     Fields:    Translation:Humans
  97. Nedzi LA, Kooy HM, Alexander E, Svensson GK, Loeffler JS. Dynamic field shaping for stereotactic radiosurgery: a modeling study. Int J Radiat Oncol Biol Phys. 1993 Apr 02; 25(5):859-69. PMID: 8478237.
    Citations: 9     Fields:    Translation:Humans
  98. Loeffler JS, Alexander E, Shea WM, Wen PY, Fine HA, Kooy HM, Black PM. Radiosurgery as part of the initial management of patients with malignant gliomas. J Clin Oncol. 1992 Sep; 10(9):1379-85. PMID: 1325539.
    Citations: 45     Fields:    Translation:Humans
  99. Holupka EJ, Kooy HM. A geometric algorithm for medical image correlations. Med Phys. 1992 Mar-Apr; 19(2):433-8. PMID: 1584142.
    Citations:    Fields:    Translation:Humans
  100. Nedzi LA, Kooy H, Alexander E, Gelman RS, Loeffler JS. Variables associated with the development of complications from radiosurgery of intracranial tumors. Int J Radiat Oncol Biol Phys. 1991 Aug; 21(3):591-9. PMID: 1907957.
    Citations: 28     Fields:    Translation:Humans
  101. Kooy HM, Nedzi LA, Loeffler JS, Alexander E, Cheng CW, Mannarino EG, Holupka EJ, Siddon RL. Treatment planning for stereotactic radiosurgery of intra-cranial lesions. Int J Radiat Oncol Biol Phys. 1991 Aug; 21(3):683-93. PMID: 1907960.
    Citations: 8     Fields:    Translation:Humans
  102. Holupka EJ, Kooy HM. Spherical harmonic expansion of cranial surfaces. Med Phys. 1991 Jul-Aug; 18(4):765-8. PMID: 1921885.
    Citations:    Fields:    Translation:Humans
  103. Loeffler JS, Alexander E, Wen PY, Shea WM, Coleman CN, Kooy HM, Fine HA, Nedzi LA, Silver B, Riese NE, et al. Results of stereotactic brachytherapy used in the initial management of patients with glioblastoma. J Natl Cancer Inst. 1990 Dec 19; 82(24):1918-21. PMID: 2250312.
    Citations: 24     Fields:    Translation:Humans
  104. Boyages J, Recht A, Connolly JL, Schnitt SJ, Gelman R, Kooy H, Love S, Osteen RT, Cady B, Silver B, et al. Early breast cancer: predictors of breast recurrence for patients treated with conservative surgery and radiation therapy. Radiother Oncol. 1990 Sep; 19(1):29-41. PMID: 2173044.
    Citations: 32     Fields:    Translation:Humans
  105. Loeffler JS, Kooy HM, Wen PY, Fine HA, Cheng CW, Mannarino EG, Tsai JS, Alexander E. The treatment of recurrent brain metastases with stereotactic radiosurgery. J Clin Oncol. 1990 Apr; 8(4):576-82. PMID: 2179476.
    Citations: 47     Fields:    Translation:HumansPHPublic Health
  106. Kooy HM, Barth NH. The verification of an inverse problem in radiation therapy. Int J Radiat Oncol Biol Phys. 1990 Feb; 18(2):433-9. PMID: 2303370.
    Citations: 1     Fields:    Translation:Humans
  107. Kooy HM, Rashid H. A three-dimensional electron pencil-beam algorithm. Phys Med Biol. 1989 Feb; 34(2):229-43. PMID: 2928387.
    Citations: 1     Fields:    
  108. Kooy HM, Kijewski PK. Quadtrees as a representation for irregularly shaped fields in radiotherapy applications. Int J Radiat Oncol Biol Phys. 1988 Nov; 15(5):1251-6. PMID: 3182356.
    Citations:    Fields:    Translation:Humans
  109. Kooy HM, Simpson LD, McFaul JA. Parallel-plate ionization chamber response in cobalt-60 irradiated transition zones. Med Phys. 1988 Mar-Apr; 15(2):199-203. PMID: 3386589.
    Citations:    Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.