Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

James C. Cusack Jr., M.D.


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01CA098871 (CUSACK, JAMES CAMPBELL) Jan 1, 2005 - Dec 31, 2010
    The Role of NF-kappaB in Chemotherapy Resistance
    Role: Principal Investigator
  2. K08CA077278 (CUSACK, JAMES CAMPBELL) Jul 1, 1999 - Jun 30, 2005
    Role: Principal Investigator
  3. R55CA075528 (CUSACK, JAMES CAMPBELL) Sep 15, 1997 - Sep 14, 2000
    Role: Principal Investigator
  4. M01RR000046 (ORRINGER, EUGENE P) Oct 1, 1974 - May 31, 2008
    General Clinical Research Center
    Role: Co-Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Sonal S, Deshpande V, Ting DT, Cusack JC, Parikh AR, Neyaz A, Pankaj A, Taylor MS, Dinaux AM, Leijssen LGJ, Boudreau C, Locascio JJ, Kunitake H, Goldstone RN, Bordeianou LG, Cauley CE, Ricciardi R, Berger DL. ASO Visual Abstract: Molecular Basis of Extramural Vascular Invasion (EMVI) in Colorectal Carcinoma : Tumor Microenvironment in EMVI-Positive Colorectal Carcinoma. Ann Surg Oncol. 2022 11; 29(12):7384-7385. PMID: 36008742.
    Citations: 1     Fields:    Translation:Humans
  2. Sonal S, Deshpande V, Ting DT, Cusack JC, Parikh AR, Neyaz A, Pankaj A, Taylor MS, Dinaux AM, Leijssen LGJ, Boudreau C, Locascio JJ, Kunitake H, Goldstone RN, Bordeianou LG, Cauley CE, Ricciardi R, Berger DL. Molecular Basis of Extramural Vascular Invasion (EMVI) in Colorectal Carcinoma. Ann Surg Oncol. 2022 Nov; 29(12):7372-7382. PMID: 35917013.
    Citations:    Fields:    Translation:Humans
  3. Elshami M, Goldstone RN, Blaszkowsky LS, Cusack JC, Hong TS, Wo JY, Qadan M. Patient Survival With ypT0N+ Following Neoadjuvant Therapy in Rectal Cancer. Dis Colon Rectum. 2022 Oct 01; 65(10):1224-1231. PMID: 35714358.
    Citations:    Fields:    
  4. Furtado FS, Wu MZ, Esfahani SA, Ferrone CR, Blaszkowsky LS, Clark JW, Ryan DP, Goyal L, Franses JW, Wo JY, Hong TS, Qadan M, Tanabe KK, Weekes CD, Cusack JC, Crafa F, Mahmood U, Anderson MA, Mojtahed A, Hahn PF, Caravan P, Kilcoyne A, Vangel M, Striar RR, Rosen BR, Catalano OA. Positron Emission Tomography/Magnetic Resonance Imaging Versus the Standard of Care Imaging in the Diagnosis of Peritoneal Carcinomatosis. Ann Surg. 2022 Feb 17. PMID: 35185121.
    Citations: 1     Fields:    
  5. Lord C, Charman T, Havdahl A, Carbone P, Anagnostou E, Boyd B, Carr T, de Vries PJ, Dissanayake C, Divan G, Freitag CM, Gotelli MM, Kasari C, Knapp M, Mundy P, Plank A, Scahill L, Servili C, Shattuck P, Simonoff E, Singer AT, Slonims V, Wang PP, Ysrraelit MC, Jellett R, Pickles A, Cusack J, Howlin P, Szatmari P, Holbrook A, Toolan C, McCauley JB. The Lancet Commission on the future of care and clinical research in autism. Lancet. 2022 01 15; 399(10321):271-334. PMID: 34883054.
    Citations: 16     Fields:    Translation:Humans
  6. Saqlain F, Shalhout SZ, Emerick KS, Kaufman HL, Chen YE, Cusack JC, Wright K, Miller DM. Diagnostic yield of staging brain magnetic resonance imaging is low in Merkel cell carcinoma: A single-institution cohort study. J Am Acad Dermatol. 2022 08; 87(2):434-435. PMID: 34499987.
    Citations:    Fields:    Translation:Humans
  7. Peponis T, Stafford C, Cusack J, Cauley C, Goldstone R, Berger D, Bordeianou L, Kunitake H, Francone T, Ricciardi R. The growing trend for no primary surgery in colorectal cancer. Colorectal Dis. 2021 10; 23(10):2659-2670. PMID: 34288327.
    Citations:    Fields:    Translation:Humans
  8. Furtado FS, Suarez-Weiss KE, Vangel M, Clark JW, Cusack JC, Hong T, Blaszkowsky L, Wo J, Striar R, Umutlu L, Daldrup-Link HE, Groshar D, Rocco R, Bordeianou L, Anderson MA, Mojtahed A, Qadan M, Ferrone C, Catalano OA. Clinical impact of PET/MRI in oligometastatic colorectal cancer. Br J Cancer. 2021 09; 125(7):975-982. PMID: 34282295; PMCID: PMC8476553.
    Citations: 2     Fields:    Translation:Humans
  9. Peponis T, Stafford C, Cusack J, Cauley C, Goldstone R, Berger D, Parikh A, Bordeianou L, Kunitake H, Francone T, Ricciardi R. The Use of Single-Agent Versus Multiple-Agent Concurrent Chemoradiotherapy in the Treatment of Locally Advanced Rectal Cancer. J Gastrointest Cancer. 2022 Sep; 53(3):557-563. PMID: 34196936.
    Citations:    Fields:    
  10. Parikh AR, Van Seventer EE, Siravegna G, Hartwig AV, Jaimovich A, He Y, Kanter K, Fish MG, Fosbenner KD, Miao B, Phillips S, Carmichael JH, Sharma N, Jarnagin J, Baiev I, Shah YS, Fetter IJ, Shahzade HA, Allen JN, Blaszkowsky LS, Clark JW, Dubois JS, Franses JW, Giantonio BJ, Goyal L, Klempner SJ, Nipp RD, Roeland EJ, Ryan DP, Weekes CD, Wo JY, Hong TS, Bordeianou L, Ferrone CR, Qadan M, Kunitake H, Berger D, Ricciardi R, Cusack JC, Raymond VM, Talasaz A, Boland GM, Corcoran RB. Minimal Residual Disease Detection using a Plasma-only Circulating Tumor DNA Assay in Patients with Colorectal Cancer. Clin Cancer Res. 2021 10 15; 27(20):5586-5594. PMID: 33926918; PMCID: PMC8530842.
    Citations: 24     Fields:    Translation:Humans
  11. McDuff SGR, Hardiman KM, Ulintz PJ, Parikh AR, Zheng H, Kim DW, Lennerz JK, Hazar-Rethinam M, Van Seventer EE, Fetter IJ, Nadres B, Eyler CE, Ryan DP, Weekes CD, Clark JW, Cusack JC, Goyal L, Zhu AX, Wo JY, Blaszkowsky LS, Allen J, Corcoran RB, Hong TS. Circulating Tumor DNA Predicts Pathologic and Clinical Outcomes Following Neoadjuvant Chemoradiation and Surgery for Patients With Locally Advanced Rectal Cancer. JCO Precis Oncol. 2021; 5. PMID: 34250394; PMCID: PMC8232395.
    Citations: 5     Fields:    Translation:Humans
  12. Qwaider YZ, Sell NM, Stafford CE, Kunitake H, Cusack JC, Ricciardi R, Bordeianou LG, Deshpande V, Goldstone RN, Cauley CE, Berger DL. Infiltrating Tumor Border Configuration is a Poor Prognostic Factor in Stage II and III Colon Adenocarcinoma. Ann Surg Oncol. 2021 Jun; 28(6):3408-3414. PMID: 33105502.
    Citations:    Fields:    Translation:Humans
  13. Sell NM, Qwaider YZ, Goldstone RN, Cauley CE, Cusack JC, Ricciardi R, Bordeianou LG, Berger DL, Kunitake H. Ten-year survival after pathologic complete response in rectal adenocarcinoma. J Surg Oncol. 2021 Jan; 123(1):293-298. PMID: 33022797.
    Citations: 4     Fields:    Translation:Humans
  14. Alty IG, Dee EC, Cusack JC, Blaszkowsky LS, Goldstone RN, Francone TD, Wo JY, Qadan M. Refusal of surgery for colon cancer: Sociodemographic disparities and survival implications among US patients with resectable disease. Am J Surg. 2021 01; 221(1):39-45. PMID: 32723488.
    Citations: 4     Fields:    Translation:Humans
  15. Debas H, Alatise OI, Balch CM, Brennan M, Cusack J, Donkor P, Jaffe BM, Mazariegos GV, Mock C, Mutiibwa D, Numann P, Nyagatuba JKM, O'Neill JA, Tarpley JL, Tesfaye S, Tefera G, Tuttle TM. Academic Partnerships in Global Surgery: An Overview American Surgical Association Working Group on Academic Global Surgery. Ann Surg. 2020 03; 271(3):460-469. PMID: 31592897.
    Citations: 1     Fields:    Translation:Humans
  16. Panda N, Solsky I, Huang EJ, Lipsitz S, Pradarelli JC, Delisle M, Cusack JC, Gadd MA, Lubitz CC, Mullen JT, Qadan M, Smith BL, Specht M, Stephen AE, Tanabe KK, Gawande AA, Onnela JP, Haynes AB. Using Smartphones to Capture Novel Recovery Metrics After Cancer Surgery. JAMA Surg. 2020 02 01; 155(2):123-129. PMID: 31657854; PMCID: PMC6820047.
    Citations: 24     Fields:    Translation:Humans
  17. Lord C, Brugha TS, Charman T, Cusack J, Dumas G, Frazier T, Jones EJH, Jones RM, Pickles A, State MW, Taylor JL, Veenstra-VanderWeele J. Autism spectrum disorder. Nat Rev Dis Primers. 2020 01 16; 6(1):5. PMID: 31949163; PMCID: PMC8900942.
    Citations: 158     Fields:    Translation:Humans
  18. Cavallaro P, Bordeianou L, Stafford C, Clark J, Berger D, Cusack J, Kunitake H, Francone T, Ricciardi R. Impact of Single-organ Metastasis to the Liver or Lung and Genetic Mutation Status on Prognosis in Stage IV Colorectal Cancer. Clin Colorectal Cancer. 2020 03; 19(1):e8-e17. PMID: 31899147.
    Citations: 7     Fields:    Translation:Humans
  19. Raoof S, Deng F, Cusack J. Abdomen distended by 31 L of cerebrospinal fluid: a peritoneal pseudocyst around a ventriculoperitoneal shunt. Lancet. 2019 12 07; 394(10214):2118. PMID: 31818411.
    Citations: 1     Fields:    Translation:Humans
  20. Raldow AC, Chen AB, Russell M, Lee PP, Hong TS, Ryan DP, Cusack JC, Wo JY. Cost-effectiveness of Short-Course Radiation Therapy vs Long-Course Chemoradiation for Locally Advanced Rectal Cancer. JAMA Netw Open. 2019 04 05; 2(4):e192249. PMID: 30977859; PMCID: PMC6481445.
    Citations: 9     Fields:    Translation:Humans
  21. Mock C, Debas H, Balch CM, Brennan M, Buyske J, Cusack J, DeMeester S, Herndon D, Le Holterman AX, Jaffe B, Kandil E, Kauffman G, Mazariegos G, sMerchant N, Numann P, Oleynikov D, Olutoye O, O'Neill J, Shackford S, Stock P, Tarpley JL, Tuttle T, Wolf S, Wren SM, Yang GP. Global Surgery: Effective Involvement of US Academic Surgery: Report of the American Surgical Association Working Group on Global Surgery. Ann Surg. 2018 10; 268(4):557-563. PMID: 30004921.
    Citations: 3     Fields:    Translation:Humans
  22. Fletcher-Watson S, Adams J, Brook K, Charman T, Crane L, Cusack J, Leekam S, Milton D, Parr JR, Pellicano E. Making the future together: Shaping autism research through meaningful participation. Autism. 2019 05; 23(4):943-953. PMID: 30095277.
    Citations: 50     Fields:    Translation:Humans
  23. Yozu M, Johncilla ME, Srivastava A, Ryan DP, Cusack JC, Doyle L, Setia N, Yang M, Lauwers GY, Odze RD, Misdraji J. Histologic and Outcome Study Supports Reclassifying Appendiceal Goblet Cell Carcinoids as Goblet Cell Adenocarcinomas, and Grading and Staging Similarly to Colonic Adenocarcinomas. Am J Surg Pathol. 2018 07; 42(7):898-910. PMID: 29579011.
    Citations: 14     Fields:    Translation:HumansCells
  24. Kishan AU, Voog JC, Wiseman J, Cook RR, Ancukiewicz M, Lee P, Ryan DP, Clark JW, Berger DL, Cusack JC, Wo JY, Hong TS. Standard fractionation external beam radiotherapy with and without intraoperative radiotherapy for locally recurrent rectal cancer: the role of local therapy in patients with a high competing risk of death from distant disease. Br J Radiol. 2017 Aug; 90(1076):20170134. PMID: 28613934; PMCID: PMC5603953.
    Citations: 2     Fields:    Translation:Humans
  25. Mitra D, Hong TS, Horick N, Rose B, Drapek LN, Blaszkowsky LS, Allen JN, Kwak EL, Murphy JE, Clark JW, Ryan DP, Cusack JC, Bordeianou LG, Berger DL, Wo JY. Long-term outcomes and toxicities of a large cohort of anal cancer patients treated with dose-painted IMRT per RTOG 0529. Adv Radiat Oncol. 2017 Apr-Jun; 2(2):110-117. PMID: 28740921; PMCID: PMC5514246.
    Citations: 18     
  26. Chan CH, Liesenfeld LF, Ferreiro-Neira I, Cusack JC. Preclinical Evaluation of Cathepsin-Based Fluorescent Imaging System for Cytoreductive Surgery. Ann Surg Oncol. 2017 Apr; 24(4):931-938. PMID: 27913947.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  27. Ferreiro-Neira I, Torres NE, Liesenfeld LF, Chan CH, Penson T, Landesman Y, Senapedis W, Shacham S, Hong TS, Cusack JC. XPO1 Inhibition Enhances Radiation Response in Preclinical Models of Rectal Cancer. Clin Cancer Res. 2016 Apr 01; 22(7):1663-73. PMID: 26603256.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  28. Erstad DJ, Tumusiime G, Cusack JC. Prognostic and Predictive Biomarkers in Colorectal Cancer: Implications for the Clinical Surgeon. Ann Surg Oncol. 2015 Oct; 22(11):3433-50. PMID: 26215192.
    Citations: 11     Fields:    Translation:HumansCells
  29. Hughes KS, Cusack JC. Genetics, Genomics, and Pharmacogenomics. Ann Surg Oncol. 2015 Oct; 22(11):3414-7. PMID: 26215191.
    Citations:    Fields:    Translation:Humans
  30. Riesel JN, Mandigo M, Gillies R, Damuse R, Farmer PE, Cusack JC, Krakauer EL, Shulman LN. Surgical palliative care in resource-limited settings. Lancet. 2015 Aug 08; 386(9993):527. PMID: 25924837.
    Citations: 2     Fields:    Translation:Humans
  31. Chao TE, Riesel JN, Anderson GA, Mullen JT, Doyle J, Briggs SM, Lillemoe KD, Goldstein C, Kitya D, Cusack JC. Building a global surgery initiative through evaluation, collaboration, and training: the Massachusetts General Hospital experience. J Surg Educ. 2015 Jul-Aug; 72(4):e21-8. PMID: 25697510.
    Citations: 5     Fields:    
  32. Chan CH, Cusack JC, Ryan DP. A critical look at local-regional management of peritoneal metastasis. Hematol Oncol Clin North Am. 2015 Feb; 29(1):153-8. PMID: 25475577.
    Citations: 4     Fields:    Translation:Humans
  33. Cercek A, Cusack JC, Ryan DP. Treatment of peritoneal carcinomatosis of colorectal origin. Am Soc Clin Oncol Educ Book. 2015; e208-11. PMID: 25993175.
    Citations: 3     Fields:    Translation:Humans
  34. Mirabeau-Beale K, Hong TS, Niemierko A, Ancukiewicz M, Blaszkowsky LS, Crowley EM, Cusack JC, Drapek LC, Kovalchuk N, Markowski M, Napolitano B, Nyamwanda J, Ryan DP, Wolfgang J, Kachnic LA, Wo JY. Clinical and treatment factors associated with vaginal stenosis after definitive chemoradiation for anal canal cancer. Pract Radiat Oncol. 2015 May-Jun; 5(3):e113-e118. PMID: 25424587.
    Citations: 13     Fields:    Translation:HumansCTClinical Trials
  35. Erstad DJ, Cusack JC. Mutational analysis of merkel cell carcinoma. Cancers (Basel). 2014 10 17; 6(4):2116-36. PMID: 25329450.
    Citations: 14     
  36. Frederick DT, Salas Fragomeni RA, Schalck A, Ferreiro-Neira I, Hoff T, Cooper ZA, Haq R, Panka DJ, Kwong LN, Davies MA, Cusack JC, Flaherty KT, Fisher DE, Mier JW, Wargo JA, Sullivan RJ. Clinical profiling of BCL-2 family members in the setting of BRAF inhibition offers a rationale for targeting de novo resistance using BH3 mimetics. PLoS One. 2014; 9(7):e101286. PMID: 24983357.
    Citations: 25     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
  37. Sahani DV, Bajwa MA, Andrabi Y, Bajpai S, Cusack JC. Current status of imaging and emerging techniques to evaluate liver metastases from colorectal carcinoma. Ann Surg. 2014 May; 259(5):861-72. PMID: 24509207.
    Citations: 19     Fields:    Translation:Humans
  38. Russo AL, Ryan DP, Borger DR, Wo JY, Szymonifka J, Liang WY, Kwak EL, Blaszkowsky LS, Clark JW, Allen JN, Zhu AX, Berger DL, Cusack JC, Mamon HJ, Haigis KM, Hong TS. Mutational and clinical predictors of pathologic complete response in the treatment of locally advanced rectal cancer. J Gastrointest Cancer. 2014 Mar; 45(1):34-9. PMID: 24006244.
    Citations: 16     Fields:    Translation:Humans
  39. Blaszkowsky LS, Ryan DP, Szymonifka J, Borger DR, Zhu AX, Clark JW, Kwak EL, Mamon HJ, Allen JN, Vasudev E, Shellito PC, Cusack JC, Berger DL, Hong TS. Phase I/II study of neoadjuvant bevacizumab, erlotinib and 5-fluorouracil with concurrent external beam radiation therapy in locally advanced rectal cancer. Ann Oncol. 2014 Jan; 25(1):121-6. PMID: 24356623.
    Citations: 12     Fields:    Translation:HumansCTClinical Trials
  40. Erstad DJ, Cusack JC. Targeting the NF-?B pathway in cancer therapy. Surg Oncol Clin N Am. 2013 Oct; 22(4):705-46. PMID: 24012396.
    Citations: 39     Fields:    Translation:HumansAnimalsCells
  41. Salas Fragomeni RA, Chung HW, Landesman Y, Senapedis W, Saint-Martin JR, Tsao H, Flaherty KT, Shacham S, Kauffman M, Cusack JC. CRM1 and BRAF inhibition synergize and induce tumor regression in BRAF-mutant melanoma. Mol Cancer Ther. 2013 Jul; 12(7):1171-9. PMID: 23615632.
    Citations: 42     Fields:    Translation:HumansAnimalsCells
  42. Kulu Y, Kawasaki H, Donahue JM, Kasuya H, Cusack JC, Choi EW, Kuruppu DK, Fuchs BC, Tanabe KK. Concurrent chemotherapy inhibits herpes simplex virus-1 replication and oncolysis. Cancer Gene Ther. 2013 Feb; 20(2):133-40. PMID: 23348635.
    Citations: 12     Fields:    Translation:HumansCells
  43. Santamaria-Barria JA, Boland GM, Yeap BY, Nardi V, Dias-Santagata D, Cusack JC. Merkel cell carcinoma: 30-year experience from a single institution. Ann Surg Oncol. 2013 Apr; 20(4):1365-73. PMID: 23208132.
    Citations: 45     Fields:    Translation:HumansCTClinical Trials
  44. Cusack JC, Hughes KS. Managing patients at high risk for hereditary breast cancer: a guide for the practicing physician. Ann Surg Oncol. 2012 Jun; 19(6):1721-2. PMID: 22411203.
    Citations: 1     Fields:    Translation:Humans
  45. Drohan B, Roche CA, Cusack JC, Hughes KS. Hereditary breast and ovarian cancer and other hereditary syndromes: using technology to identify carriers. Ann Surg Oncol. 2012 Jun; 19(6):1732-7. PMID: 22427173.
    Citations: 40     Fields:    Translation:Humans
  46. Nardi V, Song Y, Santamaria-Barria JA, Cosper AK, Lam Q, Faber AC, Boland GM, Yeap BY, Bergethon K, Scialabba VL, Tsao H, Settleman J, Ryan DP, Borger DR, Bhan AK, Hoang MP, Iafrate AJ, Cusack JC, Engelman JA, Dias-Santagata D. Activation of PI3K signaling in Merkel cell carcinoma. Clin Cancer Res. 2012 Mar 01; 18(5):1227-36. PMID: 22261808.
    Citations: 46     Fields:    Translation:HumansCells
  47. Blaszkowsky LS, Cusack JC, Hong TS, Chung DC, Blake MA, Lennerz JK. Case records of the Massachusetts General Hospital. Case 13-2011. A 49-year-old man with adenocarcinoma of the rectum. N Engl J Med. 2011 Apr 28; 364(17):1658-68. PMID: 21524217.
    Citations:    Fields:    Translation:Humans
  48. Conrad C, Podolsky MJ, Cusack JC. Antiproteasomal agents in rectal cancer. Anticancer Drugs. 2011 Apr; 22(4):341-50. PMID: 21200315.
    Citations: 5     Fields:    Translation:Humans
  49. Potts BC, Albitar MX, Anderson KC, Baritaki S, Berkers C, Bonavida B, Chandra J, Chauhan D, Cusack JC, Fenical W, Ghobrial IM, Groll M, Jensen PR, Lam KS, Lloyd GK, McBride W, McConkey DJ, Miller CP, Neuteboom ST, Oki Y, Ovaa H, Pajonk F, Richardson PG, Roccaro AM, Sloss CM, Spear MA, Valashi E, Younes A, Palladino MA. Marizomib, a proteasome inhibitor for all seasons: preclinical profile and a framework for clinical trials. Curr Cancer Drug Targets. 2011 Mar; 11(3):254-84. PMID: 21247382.
    Citations: 83     Fields:    Translation:HumansAnimals
  50. Cusack JC, Clark JW, Curley SA, Sahani DV, Zukerberg LR. Case records of the Massachusetts General Hospital: Case 3-2011: a 58-year-old woman with a mass in the liver. N Engl J Med. 2011 Jan 27; 364(4):362-70. PMID: 21268729.
    Citations:    Fields:    Translation:Humans
  51. Klos CL, Shellito PC, Rattner DW, Hodin RA, Cusack JC, Bordeianou L, Sylla P, Hong TS, Blaszkowsky L, Ryan DP, Lauwers GY, Chang Y, Berger DL. The effect of neoadjuvant chemoradiation therapy on the prognostic value of lymph nodes after rectal cancer surgery. Am J Surg. 2010 Oct; 200(4):440-5. PMID: 20887837.
    Citations: 12     Fields:    Translation:Humans
  52. Sloss CM, Wang F, Palladino MA, Cusack JC. Activation of EGFR by proteasome inhibition requires HB-EGF in pancreatic cancer cells. Oncogene. 2010 May 27; 29(21):3146-52. PMID: 20208558.
    Citations: 10     Fields:    Translation:HumansCells
  53. Blaszkowsky LS, Hong TS, Zhu AX, Kwak EL, Mamon HJ, Shellito PC, Cusack JC, Berger D, Horgan K, Ryan DP. A phase I/II study of bevacizumab (beva), erlotinib (erl), and 5-fluorouracil (5-FU) with concurrent external beam radiation therapy (RT) in locally advanced rectal cancer (LARC). J Clin Oncol. 2009 May 20; 27(15_suppl):4106. PMID: 27961180.
  54. Sloss CM, Wang F, Liu R, Xia L, Houston M, Ljungman D, Palladino MA, Cusack JC. Proteasome inhibition activates epidermal growth factor receptor (EGFR) and EGFR-independent mitogenic kinase signaling pathways in pancreatic cancer cells. Clin Cancer Res. 2008 Aug 15; 14(16):5116-23. PMID: 18698029.
    Citations: 31     Fields:    Translation:HumansAnimalsCells
  55. Donahue J, Sahani D, Tso L, Cusack JC. Extra-adrenal pheochromocytoma involving the organ of Zuckerkandl. Surgery. 2008 Jun; 143(6):830-2. PMID: 18549902.
    Citations: 1     Fields:    Translation:Humans
  56. Wang F, Sloss C, Zhang X, Lee SW, Cusack JC. Membrane-bound heparin-binding epidermal growth factor like growth factor regulates E-cadherin expression in pancreatic carcinoma cells. Cancer Res. 2007 Sep 15; 67(18):8486-93. PMID: 17875687.
    Citations: 24     Fields:    Translation:HumansCells
  57. Ryan DP, O'Neil BH, Supko JG, Rocha Lima CM, Dees EC, Appleman LJ, Clark J, Fidias P, Orlowski RZ, Kashala O, Eder JP, Cusack JC. A Phase I study of bortezomib plus irinotecan in patients with advanced solid tumors. Cancer. 2006 Dec 01; 107(11):2688-97. PMID: 17075878.
    Citations: 21     Fields:    Translation:HumansCTClinical Trials
  58. Ryan DP, Appleman LJ, Lynch T, Supko JG, Fidias P, Clark JW, Fishman M, Zhu AX, Enzinger PC, Kashala O, Cusack J, Eder JP. Phase I clinical trial of bortezomib in combination with gemcitabine in patients with advanced solid tumors. Cancer. 2006 Nov 15; 107(10):2482-9. PMID: 17036355.
    Citations: 13     Fields:    Translation:HumansCTClinical Trials
  59. Cusack JC, Liu R, Xia L, Chao TH, Pien C, Niu W, Palombella VJ, Neuteboom ST, Palladino MA. NPI-0052 enhances tumoricidal response to conventional cancer therapy in a colon cancer model. Clin Cancer Res. 2006 Nov 15; 12(22):6758-64. PMID: 17121896.
    Citations: 29     Fields:    Translation:HumansAnimalsCells
  60. Wang F, Liu R, Lee SW, Sloss CM, Couget J, Cusack JC. Heparin-binding EGF-like growth factor is an early response gene to chemotherapy and contributes to chemotherapy resistance. Oncogene. 2007 Mar 29; 26(14):2006-16. PMID: 17001310.
    Citations: 29     Fields:    Translation:HumansCells
  61. Ollila DW, Caudle AS, Cance WG, Kim HJ, Cusack JC, Swasey JE, Calvo BF. Successful minimally invasive parathyroidectomy for primary hyperparathyroidism without using intraoperative parathyroid hormone assays. Am J Surg. 2006 Jan; 191(1):52-6. PMID: 16399106.
    Citations: 11     Fields:    Translation:Humans
  62. Sahani DV, Krishnamurthy SK, Kalva S, Cusack J, Hahn PF, Santilli J, Saini S, Mueller PR. Multidetector-row computed tomography angiography for planning intra-arterial chemotherapy pump placement in patients with colorectal metastases to the liver. J Comput Assist Tomogr. 2004 Jul-Aug; 28(4):478-84. PMID: 15232378.
    Citations: 5     Fields:    Translation:Humans
  63. Cusack JC. Overcoming antiapoptotic responses to promote chemosensitivity in metastatic colorectal cancer to the liver. Ann Surg Oncol. 2003 Oct; 10(8):852-62. PMID: 14527902.
    Citations: 7     Fields:    Translation:Humans
  64. Cusack JC. Rationale for the treatment of solid tumors with the proteasome inhibitor bortezomib. Cancer Treat Rev. 2003 May; 29 Suppl 1:21-31. PMID: 12738240.
    Citations: 32     Fields:    Translation:Humans
  65. Willis R, McLeod K, Cusack J, Wotton P. Use of an implantable loop recorder to investigate syncope in a cat. J Small Anim Pract. 2003 Apr; 44(4):181-3. PMID: 12703871.
    Citations: 4     Fields:    Translation:Animals
  66. Weaver KD, Yeyeodu S, Cusack JC, Baldwin AS, Ewend MG. Potentiation of chemotherapeutic agents following antagonism of nuclear factor kappa B in human gliomas. J Neurooncol. 2003 Feb; 61(3):187-96. PMID: 12675310.
    Citations: 34     Fields:    Translation:HumansCells
  67. Cusack JC, Tanabe KK. Introduction to cancer gene therapy. Surg Oncol Clin N Am. 2002 Jul; 11(3):497-519, v. PMID: 12487054.
    Citations: 2     Fields:    Translation:HumansCells
  68. Cusack JC. Clinical trials for cancer gene therapy. Surg Oncol Clin N Am. 2002 Jul; 11(3):717-825. PMID: 12487064.
    Citations:    Fields:    Translation:Humans
  69. Curley SA, Cusack JC, Tanabe KK, Stoelzing O, Ellis LM. Advances in the treatment of liver tumors. Curr Probl Surg. 2002 May; 39(5):449-571. PMID: 12019420.
    Citations: 11     Fields:    Translation:HumansCells
  70. Russo SM, Tepper JE, Baldwin AS, Liu R, Adams J, Elliott P, Cusack JC. Enhancement of radiosensitivity by proteasome inhibition: implications for a role of NF-kappaB. Int J Radiat Oncol Biol Phys. 2001 May 01; 50(1):183-93. PMID: 11316563.
    Citations: 77     Fields:    Translation:HumansAnimalsCells
  71. Cusack JC, Liu R, Houston M, Abendroth K, Elliott PJ, Adams J, Baldwin AS. Enhanced chemosensitivity to CPT-11 with proteasome inhibitor PS-341: implications for systemic nuclear factor-kappaB inhibition. Cancer Res. 2001 May 01; 61(9):3535-40. PMID: 11325813.
    Citations: 112     Fields:    Translation:HumansAnimalsCells
  72. Owen-Schaub L, Chan H, Cusack JC, Roth J, Hill LL. Fas and Fas ligand interactions in malignant disease. Int J Oncol. 2000 Jul; 17(1):5-12. PMID: 10853011.
    Citations: 13     Fields:    Translation:HumansAnimals
  73. Cusack JC, Liu R, Baldwin AS. Inducible chemoresistance to 7-ethyl-10-[4-(1-piperidino)-1-piperidino]-carbonyloxycamptothe cin (CPT-11) in colorectal cancer cells and a xenograft model is overcome by inhibition of nuclear factor-kappaB activation. Cancer Res. 2000 May 01; 60(9):2323-30. PMID: 10811101.
    Citations: 37     Fields:    Translation:HumansAnimalsCells
  74. Cusack JC, Liu R, Baldwin AS. NF- kappa B and chemoresistance: potentiation of cancer drugs via inhibition of NF- kappa B. Drug Resist Updat. 1999 Aug; 2(4):271-273. PMID: 11504498.
    Citations: 22     Fields:    
  75. Weston BW, Hiller KM, Mayben JP, Manousos GA, Bendt KM, Liu R, Cusack JC. Expression of human alpha(1,3)fucosyltransferase antisense sequences inhibits selectin-mediated adhesion and liver metastasis of colon carcinoma cells. Cancer Res. 1999 May 01; 59(9):2127-35. PMID: 10232599.
    Citations: 29     Fields:    Translation:HumansAnimalsCells
  76. Wang CY, Cusack JC, Liu R, Baldwin AS. Control of inducible chemoresistance: enhanced anti-tumor therapy through increased apoptosis by inhibition of NF-kappaB. Nat Med. 1999 Apr; 5(4):412-7. PMID: 10202930.
    Citations: 251     Fields:    Translation:AnimalsCells
  77. Cusack JC, Tanabe KK. Cancer gene therapy. Surg Oncol Clin N Am. 1998 Jul; 7(3):421-69. PMID: 9624212.
    Citations:    Fields:    Translation:HumansAnimals
  78. Cusack JC, Seymour JF, Lerner S, Keating MJ, Pollock RE. Role of splenectomy in chronic lymphocytic leukemia. J Am Coll Surg. 1997 Sep; 185(3):237-43. PMID: 9291400.
    Citations: 2     Fields:    Translation:Humans
  79. Seymour JF, Cusack JD, Lerner SA, Pollock RE, Keating MJ. Case/control study of the role of splenectomy in chronic lymphocytic leukemia. J Clin Oncol. 1997 Jan; 15(1):52-60. PMID: 8996124.
    Citations: 7     Fields:    Translation:Humans
  80. Spitz FR, Nguyen D, Skibber JM, Cusack J, Roth JA, Cristiano RJ. In vivo adenovirus-mediated p53 tumor suppressor gene therapy for colorectal cancer. Anticancer Res. 1996 Nov-Dec; 16(6B):3415-22. PMID: 9042200.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  81. Cusack JC, Giacco GG, Cleary K, Davidson BS, Izzo F, Skibber J, Yen J, Curley SA. Survival factors in 186 patients younger than 40 years old with colorectal adenocarcinoma. J Am Coll Surg. 1996 Aug; 183(2):105-12. PMID: 8696540.
    Citations: 38     Fields:    Translation:Humans
  82. Cusack JC, Spitz FR, Nguyen D, Zhang WW, Cristiano RJ, Roth JA. High levels of gene transduction in human lung tumors following intralesional injection of recombinant adenovirus. Cancer Gene Ther. 1996 Jul-Aug; 3(4):245-9. PMID: 8853549.
    Citations: 1     Fields:    Translation:HumansCells
  83. Fuhrman GM, Leach SD, Staley CA, Cusack JC, Charnsangavej C, Cleary KR, El-Naggar AK, Fenoglio CJ, Lee JE, Evans DB. Rationale for en bloc vein resection in the treatment of pancreatic adenocarcinoma adherent to the superior mesenteric-portal vein confluence. Pancreatic Tumor Study Group. Ann Surg. 1996 Feb; 223(2):154-62. PMID: 8597509; PMCID: PMC1235091.
    Citations: 95     Fields:    Translation:Humans
  84. Evans DB, Lee JE, Leach SD, Fuhrman GM, Cusack JC, Rich TA. Vascular resection and intraoperative radiation therapy during pancreaticoduodenectomy: rationale and technique. Adv Surg. 1996; 29:235-62. PMID: 8720006.
    Citations: 5     Fields:    Translation:Humans
  85. Owen-Schaub LB, Zhang W, Cusack JC, Angelo LS, Santee SM, Fujiwara T, Roth JA, Deisseroth AB, Zhang WW, Kruzel E, et al. Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-1 expression. Mol Cell Biol. 1995 Jun; 15(6):3032-40. PMID: 7539102.
    Citations: 131     Fields:    Translation:HumansCells
  86. Cusack JC, Fuhrman GM, Lee JE, Evans DB. Managing unsuspected tumor invasion of the superior mesenteric-portal venous confluence during pancreaticoduodenectomy. Am J Surg. 1994 Oct; 168(4):352-4. PMID: 7943594.
    Citations: 21     Fields:    Translation:Humans
  87. Goedegebuure PS, Zuber M, Leonard-Vidal DL, Burger UL, Cusack JC, Chang MP, Douville LM, Eberlein TJ. Reactivation of murine tumour-infiltrating lymphocytes with solid-phase anti-CD3 antibody: in vitro cytokine production is associated with in vivo efficacy. Surg Oncol. 1994 Apr; 3(2):79-89. PMID: 7952395.
    Citations: 6     Fields:    Translation:AnimalsCells
  88. Schoof DD, Obando JA, Cusack JC, Goedegebuure PS, Brem H, Eberlein TJ. The influence of angiogenesis inhibitor AGM-1470 on immune system status and tumor growth in vitro. Int J Cancer. 1993 Oct 21; 55(4):630-5. PMID: 7691763.
    Citations: 3     Fields:    Translation:AnimalsCells
  89. Schoof DD, Hunt P, Obando JA, Cusack JC, Andrews V, Terashima Y, Eberlein TJ. Secondary cytokine production by lymphoid cells used in cellular immunotherapy. Surg Oncol. 1992 Apr; 1(2):163-72. PMID: 1341247.
    Citations: 3     Fields:    Translation:HumansCells
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact contactcatalyst.harvard.edu. For faculty or fellow appointment updates and changes, please ask your appointing department to contact HMS. For fellow personal and demographic information, contact HMS Human Resources at human_resourceshms.harvard.edu. For faculty personal and demographic information, contact HMS Office for Faculty Affairs at facappthms.harvard.edu.
Cusack's Networks
Click the
buttons for more information and interactive visualizations!
Concepts (400)
Co-Authors (97)
Similar People (60)
Same Department 
Physical Neighbors
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.