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Susan Redline, M.D.

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Biography
Boston University, BostonBA05/1979Six Year Medical Honors Program
Boston University School of Medicine, BostonMD05/1979Medicine
Harvard School Of Public Health, BostonMPH05/1986Respiratory Epidemiology
2017
William C Dement Scientific Achievement Award
2012
Scientific Recognition Award
2008
Association of American Physicians
2008
Sleep In Infancy and Childhood Award
2007
Spotlight on Women's Scholarship

Overview
I direct the Program in Sleep Medicine Epidemiology at BWH. Our goals are to conduct rigorous and population-based research to: elucidate the role of genetics, early life developmental factors, and environmental exposures on sleep health; identify how social and environmental factors shape sleep health disparities which in turn drive chronic health disparities; and identify the role of sleep interventions in improving health, including cardiovascular, metabolic, and cognitive disorders.

Within the Program, we support the following Resources:

The BWH Sleep Reading Center (www.bostonsleep.org), an international core laboratory that provides leadership in the design and implementation of sleep data collection for numerous clinical trials and cohort studies. It spearheaded efforts at establishing rigorous quality control procedures for multi-site sleep research and for integrating advanced signal processing analytics into large scale-epidemiological datasets to provide quantitative biomarkers of sleep and sleep disorders.

The National Sleep Research Resource (NSRR; www.sleepdata.org), a NHLBI-data and tool repository and community engagement resource that shares large quantities of polysomnography, actigraphy and other data coupled with tools to structure, harmonize, visualize and analyze sleep data.

The Sleep Apnea Patient-Centered Outcomes Network (MyApnea; www.myapnea.org), a web-based portal to promote sleep apnea patient support and patient engagement in research.

I am the recipient of a NHLBI Outstanding Investigator Award (R35) that supports a research and training program, Phenotypic and Genomic Signatures For Sleep Apnea. This program brings together trainees and experts in epidemiology, genetic and sleep/respiratory physiology to identify biomarkers and molecular mechanisms for sleep apnea risk, models interactions between sleep disorders and genetic risk factors (G*E), and attempts to resolve the heterogeneity in sleep apnea that predicts differences in outcomes and treatment response.

I co-direct the following multi-center clinical trials:
Pediatric Adenotonsillectomy Trial (PATS; patstrial.org)
Impact of Low Flow Oxygen on Hospital Admissions and Mortality in Heart Failure and Central Sleep Apnea (LOFT-HF; lofthf.study).

I co-lead a cohort study examining the impact of the home environment on sleep disorders among children in low income urban neighborhoods. (Environmental Assessment of Sleep in Youth).

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. U01DA059472 (WANG, RUI) Sep 30, 2023 - Aug 31, 2027
    NIH
    Value of Sleep Metrics in Predicting Opioid-Use Disorder Treatment Outcomes: Leadership and Data Coordinating Center
    Role: Co-Principal Investigator
  2. R33HL165366 (AMIN, RAOUF S.) Sep 1, 2022 - Aug 31, 2027
    NIH
    Randomized Control Trial of oxygen therapy in Children and Adolescents with Down Syndrome and Obstructive Sleep Apnea
    Role: Co-Principal Investigator
  3. R61HL165366 (AMIN, RAOUF S.) Sep 1, 2022 - Aug 31, 2024
    NIH
    Randomized Control Trial of oxygen therapy in Children and Adolescents with Down Syndrome and Obstructive Sleep Apnea
    Role: Co-Principal Investigator
  4. R01HL155395 (REDLINE, SUSAN S.) Aug 1, 2021 - Jul 31, 2026
    NIH
    The role of irregular sleep schedules as a ubiquitous marker of chronic circadian disruption in cardiometabolic disease development
    Role: Principal Investigator
  5. R01AG070867 (REDLINE, SUSAN S.) May 1, 2021 - Feb 28, 2025
    NIH
    Longitudinal Relationships Among Sleep, Cognition and Alzheimer's Disease Biomarkers: Discerning Causal Associations, Mediators and Susceptibility
    Role: Principal Investigator

Bibliographic
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.