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Frederick Robert Bieber, Ph.D.


University of Rochester School of Medicine, Rochester, NY06/1976
Medical College of Virginia, Richmond, VAPh.D.12/1981Human Genetics
Massachusetts General Hospital, Boston, MA09/1983Medical Genetics

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Buckleton J, Robertson B, Curran J, Berger C, Taylor D, Bright JA, Hicks T, Gittelson S, Evett I, Pugh S, Jackson G, Kelly H, Kalafut T, Bieber FR. A review of likelihood ratios in forensic science based on a critique of Stiffelman "No longer the Gold standard: Probabilistic genotyping is changing the nature of DNA evidence in criminal trials". Forensic Sci Int. 2020 May; 310:110251. PMID: 32203853.
    Citations:    Fields:    Translation:Humans
  2. Bright JA, Cheng K, Kerr Z, McGovern C, Kelly H, Moretti TR, Smith MA, Bieber FR, Budowle B, Coble MD, Alghafri R, Allen PS, Barber A, Beamer V, Buettner C, Russell M, Gehrig C, Hicks T, Charak J, Cheong-Wing K, Ciecko A, Davis CT, Donley M, Pedersen N, Gartside B, Granger D, Greer-Ritzheimer M, Reisinger E, Kennedy J, Grammer E, Kaplan M, Hansen D, Larsen HJ, Laureano A, Li C, Lien E, Lindberg E, Kelly C, Mallinder B, Malsom S, Yacovone-Margetts A, McWhorter A, Prajapati SM, Powell T, Shutler G, Stevenson K, Stonehouse AR, Smith L, Murakami J, Halsing E, Wright D, Clark L, Taylor DA, Buckleton J. STRmix™ collaborative exercise on DNA mixture interpretation. Forensic Sci Int Genet. 2019 05; 40:1-8. PMID: 30665115.
    Citations: 8     Fields:    Translation:HumansCells
  3. Buckleton JS, Bright JA, Gittelson S, Moretti TR, Onorato AJ, Bieber FR, Budowle B, Taylor DA. The Probabilistic Genotyping Software STRmix: Utility and Evidence for its Validity. J Forensic Sci. 2019 Mar; 64(2):393-405. PMID: 30132900.
    Citations: 9     Fields:    Translation:HumansCells
  4. Wojcik MH, Carmichael N, Bieber FR, Wiener DC, Madan R, Pober BR, Raby BA. Cover Image, Volume 173A, Number 8, August 2017. Am J Med Genet A. 2017 Aug; 173(8):i. PMID: 28703452.
    Citations:    Fields:    
  5. McNamara G, Difilippantonio M, Ried T, Bieber FR. Microscopy and Image Analysis. Curr Protoc Hum Genet. 2017 07 11; 94:4.4.1-4.4.89. PMID: 28696557.
    Citations: 3     Fields:    Translation:HumansAnimals
  6. Wojcik MH, Carmichael N, Bieber FR, Wiener DC, Madan R, Pober BR, Raby BA. A new diagnosis of Williams-Beuren syndrome in a 49-year-old man with severe bullous emphysema. Am J Med Genet A. 2017 Aug; 173(8):2235-2239. PMID: 28574231; PMCID: PMC5509496.
    Citations: 3     Fields:    Translation:HumansCells
  7. Bieber FR, Cherry AM, Emanuel BS, Francke U, Hoyme HE, Jackson LG, Morton CC, Muenke M, Powell CM, Punnett HH, Rao PN, Schwartz S, Stevenson RE, Van Dyke DL. Commentary on the decision of the American Board of Medical Genetics and Genomics to create a 24-month specialty of Laboratory Genetics and Genomics. Genet Med. 2017 03; 19(3):294-296. PMID: 27854359.
    Citations:    Fields:    Translation:Humans
  8. Bieber FR, Buckleton JS, Budowle B, Butler JM, Coble MD. Evaluation of forensic DNA mixture evidence: protocol for evaluation, interpretation, and statistical calculations using the combined probability of inclusion. BMC Genet. 2016 08 31; 17(1):125. PMID: 27580588; PMCID: PMC5007818.
    Citations: 13     Fields:    Translation:Humans
  9. Giersch ABS, Bieber FR, Dubuc AM, Fletcher JA, Ligon AH, Mason-Suares H, Morton CC, Weremowicz S, Xiao S, Cin PD. Reporting of Diagnostic Cytogenetic Results. Curr Protoc Hum Genet. 2016 Apr 01; 89:A.1D.1-A.1D.23. PMID: 27037490.
    Citations:    Fields:    Translation:Humans
  10. Ligon AH, Morton CC, Bieber FR, Fletcher JA, Giersch AB, Kantarci S, Leach N, Lee C, Sandstrom M, Weremowicz S, Xiao S, Dal Cin P. Reporting of diagnostic cytogenetic results. Curr Protoc Hum Genet. 2011 Jul; Appendix 1:1D. PMID: 21735374.
    Citations:    Fields:    Translation:Humans
  11. Ligon AH, Morton CC, Bieber FR, Fletcher JA, Giersch AB, Kantarci S, Leach N, Lee C, Sandstrom M, Weremowicz S, Xiao S, Dal Cin P. Reporting of diagnostic cytogenetic results. Curr Protoc Hum Genet. 2010 Oct; Appendix 1:1D.1-23. PMID: 20891028.
    Citations:    Fields:    Translation:Humans
  12. Bieber FR, Brenner CH, Lazer D. Human genetics. Finding criminals through DNA of their relatives. Science. 2006 Jun 02; 312(5778):1315-6. PMID: 16690817.
    Citations: 26     Fields:    Translation:Humans
  13. Bieber FR. Turning base hits into earned runs: improving the effectiveness of forensic DNA data bank programs. J Law Med Ethics. 2006; 34(2):222-33. PMID: 16789945.
    Citations: 2     Fields:    Translation:Humans
  14. Biesecker LG, Bailey-Wilson JE, Ballantyne J, Baum H, Bieber FR, Brenner C, Budowle B, Butler JM, Carmody G, Conneally PM, Duceman B, Eisenberg A, Forman L, Kidd KK, Leclair B, Niezgoda S, Parsons TJ, Pugh E, Shaler R, Sherry ST, Sozer A, Walsh A. Epidemiology. DNA identifications after the 9/11 World Trade Center attack. Science. 2005 Nov 18; 310(5751):1122-3. PMID: 16293742.
    Citations: 24     Fields:    Translation:Humans
  15. Budimlija ZM, Lechpammer M, Popiolek D, Fogt F, Prinz M, Bieber FR. Forensic applications of laser capture microdissection: use in DNA-based parentage testing and platform validation. Croat Med J. 2005 Aug; 46(4):549-55. PMID: 16100757.
    Citations: 13     Fields:    Translation:Humans
  16. Budowle B, Bieber FR, Eisenberg AJ. Forensic aspects of mass disasters: strategic considerations for DNA-based human identification. Leg Med (Tokyo). 2005 Jul; 7(4):230-43. PMID: 15975517.
    Citations: 24     Fields:    Translation:Humans
  17. Ligon AH, Morton CC, Bieber FR, Fletcher JA, Giersch AB, Lee C, Sandstrom M, Weremowicz S, Xiao S, Dal Cin P. Reporting of diagnostic cytogenetic results. Curr Protoc Hum Genet. 2004 Nov; Appendix 1:Appendix 1D. PMID: 18428350.
    Citations:    Fields:    Translation:Humans
  18. Bieber FR, Lazer D. Guilt by association: should the law be able to use one person's DNA to carry out surveillance on their family? Not without a public debate. New Sci. 2004 Oct 23-29; 184(2470):20. PMID: 15573446.
    Citations: 3     Fields:    Translation:Humans
  19. Ladd C, Lee HC, Yang N, Bieber FR. Interpretation of complex forensic DNA mixtures. Croat Med J. 2001 Jun; 42(3):244-6. PMID: 11387631.
    Citations: 8     Fields:    Translation:Humans
  20. Bing DH, Bieber FR. Manual methods for PCR-based forensic DNA analysis. Curr Protoc Hum Genet. 2001 May; Chapter 14:Unit 14.6. PMID: 18428263.
    Citations:    Fields:    Translation:HumansCells
  21. Bing DH, Bieber FR. Collecting and handling samples for parentage and forensics DNA-based genetic testing. Curr Protoc Hum Genet. 2001 May; Chapter 14:Unit 14.2. PMID: 18428259.
    Citations:    Fields:    Translation:HumansCells
  22. Bieber FR. Overview of human identity testing and forensic genetics. Curr Protoc Hum Genet. 2001 May; Chapter 14:Unit 14.1. PMID: 18428258.
    Citations:    Fields:    Translation:Humans
  23. Bing DH, Bieber FR, Holland MM, Huffine EF. Isolation of DNA from forensic evidence. Curr Protoc Hum Genet. 2001 May; Chapter 14:Unit 14.3. PMID: 18428260.
    Citations: 1     Fields:    Translation:Humans
  24. Bing DH, Bieber FR. RFLP analysis of forensic DNA samples with single-locus VNTR genetic markers. Curr Protoc Hum Genet. 2001 May; Chapter 14:Unit 14.5. PMID: 18428262.
    Citations:    Fields:    Translation:HumansCells
  25. Weremowicz S, Sandstrom DJ, Morton CC, Niedzwiecki CA, Sandstrom MM, Bieber FR. Fluorescence in situ hybridization (FISH) for rapid detection of aneuploidy: experience in 911 prenatal cases. Prenat Diagn. 2001 Apr; 21(4):262-9. PMID: 11288114.
    Citations: 2     Fields:    Translation:HumansCells
  26. Ing PS, Van Dyke DL, Caudill SP, Reidy JA, Bice G, Bieber FR, Buchanan PD, Carroll AJ, Cheung SW, DeWald G, Donahue RP, Gardner HA, Higgins J, Hsu LY, Jamehdor M, Keitges EA, Laundon CH, Luthardt FW, Mascarello J, May KM, Meck JM, Morton C, Patil S, Peakman D, Pettenati MJ, Rao N, Sanger WG, Saxe DF, Schwartz S, Sekhon GS, Vance GH, Wyandt HE, Yu CW, Zenger-Hain J, Chen AT. Detection of mosaicism in amniotic fluid cultures: a CYTO2000 collaborative study. Genet Med. 1999 Mar-Apr; 1(3):94-7. PMID: 11336459.
    Citations:    Fields:    Translation:HumansCells
  27. French CA, Bieber FR, Bing DH, Genest DR. Twins, placentas, and genetics: acardiac twinning in a dichorionic, diamniotic, monozygotic twin gestation. Hum Pathol. 1998 Sep; 29(9):1028-31. PMID: 9744324.
    Citations: 4     Fields:    Translation:Humans
  28. Robertson NG, Skvorak AB, Yin Y, Weremowicz S, Johnson KR, Kovatch KA, Battey JF, Bieber FR, Morton CC. Mapping and characterization of a novel cochlear gene in human and in mouse: a positional candidate gene for a deafness disorder, DFNA9. Genomics. 1997 Dec 15; 46(3):345-54. PMID: 9441737.
    Citations: 41     Fields:    Translation:HumansAnimalsCells
  29. Skvorak AB, Robertson NG, Yin Y, Weremowicz S, Her H, Bieber FR, Beisel KW, Lynch ED, Beier DR, Morton CC. An ancient conserved gene expressed in the human inner ear: identification, expression analysis, and chromosomal mapping of human and mouse antiquitin (ATQ1). Genomics. 1997 Dec 01; 46(2):191-9. PMID: 9417906.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  30. Rasmussen SA, Bieber FR, Benacerraf BR, Lachman RS, Rimoin DL, Holmes LB. Epidemiology of osteochondrodysplasias: changing trends due to advances in prenatal diagnosis. Am J Med Genet. 1996 Jan 02; 61(1):49-58. PMID: 8741918.
    Citations: 17     Fields:    Translation:Humans
  31. Doss BJ, Greene MF, Hill J, Heffner LJ, Bieber FR, Genest DR. Massive chronic intervillositis associated with recurrent abortions. Hum Pathol. 1995 Nov; 26(11):1245-51. PMID: 7590700.
    Citations: 4     Fields:    Translation:HumansCells
  32. Magovcevic I, Khetarpal U, Bieber FR, Morton CC. GNAZ in human fetal cochlea: expression, localization, and potential role in inner ear function. Hear Res. 1995 Oct; 90(1-2):55-64. PMID: 8975005.
    Citations: 1     Fields:    Translation:HumansCells
  33. Genest DR, Roberts D, Boyd T, Bieber FR. Fetoplacental histology as a predictor of karyotype: a controlled study of spontaneous first trimester abortions. Hum Pathol. 1995 Feb; 26(2):201-9. PMID: 7860050.
    Citations: 2     Fields:    Translation:Humans
  34. Lutz B, Kuratani S, Rugarli EI, Wawersik S, Wong C, Bieber FR, Ballabio A, Eichele G. Expression of the Kallmann syndrome gene in human fetal brain and in the manipulated chick embryo. Hum Mol Genet. 1994 Oct; 3(10):1717-23. PMID: 7849694.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  35. Robertson NG, Khetarpal U, Gutiérrez-Espeleta GA, Bieber FR, Morton CC. Isolation of novel and known genes from a human fetal cochlear cDNA library using subtractive hybridization and differential screening. Genomics. 1994 Sep 01; 23(1):42-50. PMID: 7829101.
    Citations: 49     Fields:    Translation:HumansCells
  36. Gibson CC, Genest DR, Bieber FR, Holmes LB. X-linked phenotype of absent radius and anogenital anomalies. Am J Med Genet. 1993 Mar 15; 45(6):743-4. PMID: 8456854.
    Citations:    Fields:    Translation:HumansCells
  37. Benacerraf BR, Pauker S, Quade BJ, Bieber FR. Prenatal sonography in trisomy 9. Prenat Diagn. 1992 Mar; 12(3):175-81. PMID: 1589419.
    Citations:    Fields:    Translation:HumansCells
  38. Bieber FR, Dawson AE, Holmes LB. Etiologic complexities of diaphragmatic defects: right diaphragmatic hernia, pulmonary hypoplasia/agenesis, and hydrocephalus in sibs. Am J Med Genet. 1991 Nov 01; 41(2):164-8. PMID: 1723847.
    Citations:    Fields:    Translation:Humans
  39. Genest DR, Driscoll SG, Bieber FR. Complexities of limb anomalies: the lower extremity in the "prune belly" phenotype. Teratology. 1991 Oct; 44(4):365-71. PMID: 1962283.
    Citations:    Fields:    Translation:Humans
  40. Fisher EM, Beer-Romero P, Brown LG, Ridley A, McNeil JA, Lawrence JB, Willard HF, Bieber FR, Page DC. Homologous ribosomal protein genes on the human X and Y chromosomes: escape from X inactivation and possible implications for Turner syndrome. Cell. 1990 Dec 21; 63(6):1205-18. PMID: 2124517.
    Citations: 113     Fields:    Translation:HumansCells
  41. Morse RP, Rockenmacher S, Pyeritz RE, Sanders SP, Bieber FR, Lin A, MacLeod P, Hall B, Graham JM. Diagnosis and management of infantile marfan syndrome. Pediatrics. 1990 Dec; 86(6):888-95. PMID: 2251026.
    Citations: 29     Fields:    Translation:Humans
  42. Bieber FR, Hoffman EP. Duchenne and Becker muscular dystrophies: genetics, prenatal diagnosis, and future prospects. Clin Perinatol. 1990 Dec; 17(4):845-65. PMID: 2286031.
    Citations: 9     Fields:    Translation:HumansPHPublic Health
  43. Bieber FR, Hoffman EP, Amos JA. Dystrophin analysis in duchenne muscular dystrophy: use in fetal diagnosis and in genetic counseling. Am J Hum Genet. 1989 Sep; 45(3):362-7. PMID: 2672800; PMCID: PMC1683403.
    Citations: 5     Fields:    Translation:Humans
  44. Benson CB, Bieber FR, Genest DR, Doubilet PM. Doppler demonstration of reversed umbilical blood flow in an acardiac twin. J Clin Ultrasound. 1989 May; 17(4):291-5. PMID: 2497149.
    Citations:    Fields:    Translation:Humans
  45. Lage JM, Weinberg DS, Yavner DL, Bieber FR. The biology of tetraploid hydatidiform moles: histopathology, cytogenetics, and flow cytometry. Hum Pathol. 1989 May; 20(5):419-25. PMID: 2707792.
    Citations: 3     Fields:    Translation:Humans
  46. Mills JL, Simpson JL, Driscoll SG, Jovanovic-Peterson L, Van Allen M, Aarons JH, Metzger B, Bieber FR, Knopp RH, Holmes LB, et al. Incidence of spontaneous abortion among normal women and insulin-dependent diabetic women whose pregnancies were identified within 21 days of conception. N Engl J Med. 1988 Dec 22; 319(25):1617-23. PMID: 3200277.
    Citations: 41     Fields:    Translation:Humans
  47. Mills JL, Knopp RH, Simpson JL, Jovanovic-Peterson L, Metzger BE, Holmes LB, Aarons JH, Brown Z, Reed GF, Bieber FR, et al. Lack of relation of increased malformation rates in infants of diabetic mothers to glycemic control during organogenesis. N Engl J Med. 1988 Mar 17; 318(11):671-6. PMID: 3344018.
    Citations: 53     Fields:    Translation:Humans
  48. Lage JM, VanMarter LJ, Bieber FR. Questionable role of amniocentesis in the etiology of amniotic band formation. A case report. J Reprod Med. 1988 Jan; 33(1):71-3. PMID: 3351810.
    Citations: 1     Fields:    Translation:Humans
  49. Sieff CA, Niemeyer CM, Nathan DG, Ekern SC, Bieber FR, Yang YC, Wong G, Clark SC. Stimulation of human hematopoietic colony formation by recombinant gibbon multi-colony-stimulating factor or interleukin 3. J Clin Invest. 1987 Sep; 80(3):818-23. PMID: 3497952; PMCID: PMC442308.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  50. Lage JM, Driscoll SG, Bieber FR. Transposition of the external genitalia associated with caudal regression. J Urol. 1987 Aug; 138(2):387-9. PMID: 3599260.
    Citations:    Fields:    Translation:Humans
  51. Freedman AS, Boyd AW, Bieber FR, Daley J, Rosen K, Horowitz JC, Levy DN, Nadler LM. Normal cellular counterparts of B cell chronic lymphocytic leukemia. Blood. 1987 Aug; 70(2):418-27. PMID: 3496927.
    Citations: 11     Fields:    Translation:HumansCells
  52. Farhood AI, Morris JH, Bieber FR. Transient cysts of the fetal choroid plexus: morphology and histogenesis. Am J Med Genet. 1987 Aug; 27(4):977-82. PMID: 3321997.
    Citations: 6     Fields:    Translation:HumansCells
  53. Lewis BD, Doubilet PM, Heller VL, Bierre A, Bieber FR. Cutaneous and visceral hemangiomata in the Klippel-Trenaunay-Weber syndrome: antenatal sonographic detection. AJR Am J Roentgenol. 1986 Sep; 147(3):598-600. PMID: 3017080.
    Citations: 1     Fields:    Translation:Humans
  54. Bieber FR, Mortimer G, Kolodny EH, Driscoll SG. Pathologic findings in fetal GM1 gangliosidosis. Arch Neurol. 1986 Jul; 43(7):736-8. PMID: 3089200.
    Citations: 2     Fields:    Translation:Humans
  55. Joseph MP, Goodman ML, Pilch BZ, Bieber FR, Holmes LB, Reardon E. Heterotopic cervical salivary gland tissue in a family with probable branchio-otorenal syndrome. Head Neck Surg. 1986 Jul-Aug; 8(6):456-62. PMID: 3721888.
    Citations:    Fields:    Translation:Humans
  56. Cayea PD, Bieber FR, Ross MJ, Davidoff A, Osathanondh R, Jones TB. Sonographic findings in otocephaly (synotia). J Ultrasound Med. 1985 Jul; 4(7):377-9. PMID: 3925160.
    Citations:    Fields:    Translation:Humans
  57. Duker JS, Weiss JS, Siber M, Bieber FR, Albert DM. Ocular findings in a new heritable syndrome of brain, eye, and urogenital abnormalities. Am J Ophthalmol. 1985 Jan 15; 99(1):51-5. PMID: 3917610.
    Citations: 3     Fields:    Translation:Humans
  58. Bieber FR, Mostoufi-zadeh M, Birnholz JC, Driscoll SG. Amniotic band sequence associated with ectopia cordis in one twin. J Pediatr. 1984 Nov; 105(5):817-9. PMID: 6389809.
    Citations: 3     Fields:    Translation:Humans
  59. Benacerraf BR, Frigoletto FD, Bieber FR. The fetal face: ultrasound examination. Radiology. 1984 Nov; 153(2):495-7. PMID: 6385109.
    Citations: 1     Fields:    Translation:Humans
  60. Benacerraf B, Osathanondh R, Bieber FR. Achondrogenesis type I: ultrasound diagnosis in utero. J Clin Ultrasound. 1984 Jul-Aug; 12(6):357-9. PMID: 6438165.
    Citations: 1     Fields:    Translation:Humans
  61. Balcar I, Bieber FR. Sonographic and radiologic findings in campomelic dysplasia. AJR Am J Roentgenol. 1983 Sep; 141(3):481-2. PMID: 6603755.
    Citations:    Fields:    Translation:Humans
  62. Bieber FR, Nance WE, Morton CC, Brown JA, Redwine FO, Jordan RL, Mohanakumar T. Genetic studies of an acardiac monster: evidence of polar body twinning in man. Science. 1981 Aug 14; 213(4509):775-7. PMID: 7196086.
    Citations: 9     Fields:    Translation:Humans
  63. Bieber FR. Comments on "a Turner-like phenotype in the aborted fetus". Teratology. 1981 Jun; 23(3):418. PMID: 7256664.
    Citations:    Fields:    Translation:Humans
  64. Bieber FR, Redwine FO. Neural tube defects in two offspring of an affected female. Lancet. 1980 Nov 29; 2(8205):1202. PMID: 6107806.
    Citations: 1     Fields:    Translation:Humans
  65. Bieber FR, Petres RE, Bieber JM, Nance WE. Prenatal detection of a familial nuchal bleb simulating encephalocele. Birth Defects Orig Artic Ser. 1979; 15(5A):51-61. PMID: 508920.
    Citations: 1     Fields:    Translation:Humans
  66. Bieber FR, Petres RE. Ethical problems of screening for neural-tube defects. Lancet. 1978 Aug 12; 2(8085):374-5. PMID: 79738.
    Citations: 1     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.