Harvard Catalyst Profiles

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David Lee Owen, Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Owen DL, La Rue RS, Munro SA, Farrar MA. Tracking Regulatory T Cell Development in the Thymus Using Single-Cell RNA Sequencing/TCR Sequencing. J Immunol. 2022 10 01; 209(7):1300-1313. PMID: 36038290; PMCID: PMC9529998.
    Citations: 1     Fields:    Translation:AnimalsCells
  2. Sjaastad LE, Owen DL, Tracy SI, Farrar MA. Phenotypic and Functional Diversity in Regulatory T Cells. Front Cell Dev Biol. 2021; 9:715901. PMID: 34631704.
    Citations: 2     
  3. Owen DL, Sjaastad LE, Farrar MA. Regulatory T Cell Development in the Thymus. J Immunol. 2019 10 15; 203(8):2031-2041. PMID: 31591259; PMCID: PMC6910132.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  4. Owen DL, Farrar MA. In vitro Differentiation of Thymic Treg Cell Progenitors to Mature Thymic Treg Cells. Bio Protoc. 2019 Aug 20; 9(16):e3335. PMID: 33654840; PMCID: PMC7854127.
  5. Owen DL, Mahmud SA, Sjaastad LE, Williams JB, Spanier JA, Simeonov DR, Ruscher R, Huang W, Proekt I, Miller CN, Hekim C, Jeschke JC, Aggarwal P, Broeckel U, LaRue RS, Henzler CM, Alegre ML, Anderson MS, August A, Marson A, Zheng Y, Williams CB, Farrar MA. Thymic regulatory T cells arise via two distinct developmental programs. Nat Immunol. 2019 02; 20(2):195-205. PMID: 30643267.
    Citations: 65     Fields:    Translation:HumansAnimalsCells
  6. Wang H, Owen DL, Qian LJ, Chopp LB, Farrar MA, Hogquist KA. Ultrasound Guided Intra-thymic Injection to Track Recent Thymic Emigrants and Investigate T Cell Development. Bio Protoc. 2018 Dec 05; 8(23):e3107. PMID: 35921147.
  7. Owen DL, Mahmud SA, Vang KB, Kelly RM, Blazar BR, Smith KA, Farrar MA. Identification of Cellular Sources of IL-2 Needed for Regulatory T Cell Development and Homeostasis. J Immunol. 2018 06 15; 200(12):3926-3933. PMID: 29728511; PMCID: PMC5988981.
    Citations: 28     Fields:    Translation:AnimalsCells
  8. Owen DL, Farrar MA. STAT5 and CD4 + T Cell Immunity. F1000Res. 2017; 6:32. PMID: 28163905.
    Citations: 19     Fields:    
  9. Balachandran RS, Heighington CS, Starostina NG, Anderson JW, Owen DL, Vasudevan S, Kipreos ET. The ubiquitin ligase CRL2ZYG11 targets cyclin B1 for degradation in a conserved pathway that facilitates mitotic slippage. J Cell Biol. 2016 Oct 24; 215(2):151-166. PMID: 27810909; PMCID: PMC5084644.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  10. Mahmud SA, Manlove LS, Schmitz HM, Xing Y, Wang Y, Owen DL, Schenkel JM, Boomer JS, Green JM, Yagita H, Chi H, Hogquist KA, Farrar MA. Costimulation via the tumor-necrosis factor receptor superfamily couples TCR signal strength to the thymic differentiation of regulatory T cells. Nat Immunol. 2014 May; 15(5):473-81. PMID: 24633226.
    Citations: 115     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.