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Elizabeth Silagi, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Silagi ES, Segal RA. Uncomfortably numb: how Nav1.7 mediates paclitaxel-induced peripheral neuropathy. Brain. 2021 07 28; 144(6):1621-1623. PMID: 34009327; PMCID: PMC8320290.
    Citations: 1     Fields:    Translation:Humans
  2. Silagi ES, Schipani E, Shapiro IM, Risbud MV. The role of HIF proteins in maintaining the metabolic health of the intervertebral disc. Nat Rev Rheumatol. 2021 07; 17(7):426-439. PMID: 34083809.
    Citations: 7     Fields:    Translation:HumansAnimals
  3. Fukuda Y, Pazyra-Murphy MF, Silagi ES, Tasdemir-Yilmaz OE, Li Y, Rose L, Yeoh ZC, Vangos NE, Geffken EA, Seo HS, Adelmant G, Bird GH, Walensky LD, Marto JA, Dhe-Paganon S, Segal RA. Binding and transport of SFPQ-RNA granules by KIF5A/KLC1 motors promotes axon survival. J Cell Biol. 2021 01 04; 220(1). PMID: 33284322.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  4. Madhu V, Boneski PK, Silagi E, Qiu Y, Kurland I, Guntur AR, Shapiro IM, Risbud MV. Hypoxic Regulation of Mitochondrial Metabolism and Mitophagy in Nucleus Pulposus Cells Is Dependent on HIF-1a-BNIP3 Axis. J Bone Miner Res. 2020 08; 35(8):1504-1524. PMID: 32251541.
    Citations: 23     Fields:    Translation:AnimalsCells
  5. Silagi ES, Novais EJ, Bisetto S, Telonis AG, Snuggs J, Le Maitre CL, Qiu Y, Kurland IJ, Shapiro IM, Philp NJ, Risbud MV. Lactate Efflux From Intervertebral Disc Cells Is Required for Maintenance of Spine Health. J Bone Miner Res. 2020 03; 35(3):550-570. PMID: 31692093.
    Citations: 16     Fields:    Translation:Humans
  6. Choi H, Tessier S, Silagi ES, Kyada R, Yousefi F, Pleshko N, Shapiro IM, Risbud MV. A novel mouse model of intervertebral disc degeneration shows altered cell fate and matrix homeostasis. Matrix Biol. 2018 09; 70:102-122. PMID: 29605718; PMCID: PMC6081256.
    Citations: 44     Fields:    Translation:HumansAnimalsCells
  7. Silagi ES, Batista P, Shapiro IM, Risbud MV. Expression of Carbonic Anhydrase III, a Nucleus Pulposus Phenotypic Marker, is Hypoxia-responsive and Confers Protection from Oxidative Stress-induced Cell Death. Sci Rep. 2018 03 20; 8(1):4856. PMID: 29559661.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  8. Silagi ES, Shapiro IM, Risbud MV. Glycosaminoglycan synthesis in the nucleus pulposus: Dysregulation and the pathogenesis of disc degeneration. Matrix Biol. 2018 10; 71-72:368-379. PMID: 29501510; PMCID: PMC6119535.
    Citations: 45     Fields:    Translation:HumansCells
  9. Silagi ES, Schoepflin ZR, Seifert EL, Merceron C, Schipani E, Shapiro IM, Risbud MV. Bicarbonate Recycling by HIF-1-Dependent Carbonic Anhydrase Isoforms 9 and 12 Is Critical in Maintaining Intracellular pH and Viability of Nucleus Pulposus Cells. J Bone Miner Res. 2018 02; 33(2):338-355. PMID: 28940640; PMCID: PMC5947995.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  10. Schoepflin ZR, Silagi ES, Shapiro IM, Risbud MV. PHD3 is a transcriptional coactivator of HIF-1a in nucleus pulposus cells independent of the PKM2-JMJD5 axis. FASEB J. 2017 09; 31(9):3831-3847. PMID: 28495754; PMCID: PMC5572688.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  11. Suyama K, Silagi ES, Choi H, Sakabe K, Mochida J, Shapiro IM, Risbud MV. Circadian factors BMAL1 and RORa control HIF-1a transcriptional activity in nucleus pulposus cells: implications in maintenance of intervertebral disc health. Oncotarget. 2016 Apr 26; 7(17):23056-71. PMID: 27049729.
    Citations: 14     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.