Harvard Catalyst Profiles

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Jordan Manek Chinai, Ph.D., M.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Wei Y, Ren X, Galbo PM, Moerdler S, Wang H, Sica RA, Etemad-Gilbertson B, Shi L, Zhu L, Tang X, Lin Q, Peng M, Guan F, Zheng D, Chinai JM, Zang X. KIR3DL3-HHLA2 is a human immunosuppressive pathway and a therapeutic target. Sci Immunol. 2021 Jul 09; 6(61). PMID: 34244312.
    Citations:    Fields:    
  2. Cheng H, Janakiram M, Borczuk A, Lin J, Qiu W, Liu H, Chinai JM, Halmos B, Perez-Soler R, Zang X. HHLA2, a New Immune Checkpoint Member of the B7 Family, Is Widely Expressed in Human Lung Cancer and Associated with EGFR Mutational Status. Clin Cancer Res. 2017 Feb 01; 23(3):825-832. PMID: 27553831.
    Citations: 29     Fields:    Translation:HumansCells
  3. Koirala P, Roth ME, Gill J, Chinai JM, Ewart MR, Piperdi S, Geller DS, Hoang BH, Fatakhova YV, Ghorpade M, Zang X, Gorlick R. HHLA2, a member of the B7 family, is expressed in human osteosarcoma and is associated with metastases and worse survival. Sci Rep. 2016 08 17; 6:31154. PMID: 27531281.
    Citations: 28     Fields:    Translation:HumansCells
  4. Koirala P, Roth ME, Gill J, Piperdi S, Chinai JM, Geller DS, Hoang BH, Park A, Fremed MA, Zang X, Gorlick R. Immune infiltration and PD-L1 expression in the tumor microenvironment are prognostic in osteosarcoma. Sci Rep. 2016 07 26; 6:30093. PMID: 27456063.
    Citations: 84     Fields:    Translation:HumansCells
  5. Chinai JM, Janakiram M, Chen F, Chen W, Kaplan M, Zang X. New immunotherapies targeting the PD-1 pathway. Trends Pharmacol Sci. 2015 Sep; 36(9):587-95. PMID: 26162965.
    Citations: 52     Fields:    Translation:HumansAnimals
  6. Janakiram M, Chinai JM, Zhao A, Sparano JA, Zang X. HHLA2 and TMIGD2: new immunotherapeutic targets of the B7 and CD28 families. Oncoimmunology. 2015 Aug; 4(8):e1026534. PMID: 26405587.
    Citations: 31     
  7. Janakiram M, Chinai JM, Fineberg S, Fiser A, Montagna C, Medavarapu R, Castano E, Jeon H, Ohaegbulam KC, Zhao R, Zhao A, Almo SC, Sparano JA, Zang X. Expression, Clinical Significance, and Receptor Identification of the Newest B7 Family Member HHLA2 Protein. Clin Cancer Res. 2015 May 15; 21(10):2359-66. PMID: 25549724.
    Citations: 51     Fields:    Translation:HumansAnimalsCells
  8. Jeon H, Vigdorovich V, Garrett-Thomson SC, Janakiram M, Ramagopal UA, Abadi YM, Lee JS, Scandiuzzi L, Ohaegbulam KC, Chinai JM, Zhao R, Yao Y, Mao Y, Sparano JA, Almo SC, Zang X. Structure and cancer immunotherapy of the B7 family member B7x. Cell Rep. 2014 Nov 06; 9(3):1089-98. PMID: 25437562.
    Citations: 27     Fields:    Translation:HumansAnimalsCells
  9. Zhao R, Chinai JM, Buhl S, Scandiuzzi L, Ray A, Jeon H, Ohaegbulam KC, Ghosh K, Zhao A, Scharff MD, Zang X. HHLA2 is a member of the B7 family and inhibits human CD4 and CD8 T-cell function. Proc Natl Acad Sci U S A. 2013 Jun 11; 110(24):9879-84. PMID: 23716685.
    Citations: 62     Fields:    Translation:HumansAnimalsCells
  10. Sroubek J, Krishnan Y, Chinai J, Buhl S, Scharff MD, McDonald TV. The use of Bcl-2 over-expression to stabilize hybridomas specific to the HERG potassium channel. J Immunol Methods. 2012 Jan 31; 375(1-2):215-22. PMID: 22107967.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  11. Chinai JM, Taylor AB, Ryno LM, Hargreaves ND, Morris CA, Hart PJ, Urbach AR. Molecular recognition of insulin by a synthetic receptor. J Am Chem Soc. 2011 Jun 15; 133(23):8810-3. PMID: 21473587.
    Citations: 50     Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.