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Ryan Jane Jacoby, Ph.D.

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Biography
University of North Carolina at Chapel Hill, Chapel Hill, NCPh.D.08/2017Clinical Psychology
Williams College, Williamstown, MAB.A.06/2009Psychology

Overview
Ryan Jane Jacoby, Ph.D. is a staff psychologist the OCD and Related Disorders Program at Massachusetts General Hospital (MGH) and an Instructor in Psychology (Psychiatry) at Harvard Medical School (HMS). Dr. Jacoby completed her undergraduate studies at Williams College and her Ph.D. in Clinical Psychology at the University of North Carolina at Chapel Hill. She completed her clinical internship and post-doctoral training at MGH/HMS. Dr. Jacoby is a licensed clinical psychologist who sees patients through the MGH OCD and Related Disorders Program. Her clinical and research interests are broadly focused on the nature and treatment of OCD and anxiety disorders, including specific interests in psychological mechanisms of change in exposure-based therapy for OCD and anxiety-related problems (e.g., inhibitory learning approaches to exposure) as well as treatment augmentation strategies that capitalize on these mechanisms of action. She is also interested in transdiagnostic psychological processes (e.g., intolerance of uncertainty) as well as improving behavioral and psychophysiological measurement of these processes and therapy outcomes. Dr. Jacoby is currently funded by the Charles King Trust Post-Doctoral Fellowship and the International OCD Foundation Young Investigator Research Award, with supplemental internal funding from the Harvard University Mind Brain Behavior Initiative, Livingston Fellowship Award, and Foundations of Human Behavior Grant. She was a 2018 recipient of the Anxiety and Depression Association of America (ADAA) Alies Muskin Career Development Leadership Program Award.

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. K23MH120351 (JACOBY, RYAN JANE) Apr 1, 2020 - Mar 31, 2025
    NIH/NIMH
    Targeting Attentional and Cognitive Control to Enhance the Transdiagnostic Treatment of Repetitive Negative Thinking
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Baker AW, Hellberg SN, Jacoby RJ, Losiewicz OM, Orr S, Marques L, Simon NM. A pilot study augmenting cognitive behavioral therapy for panic disorder with attention bias modification: Clinical and psychophysiological outcomes. J Behav Ther Exp Psychiatry. 2020 Sep; 68:101568. PMID: 32224333.
    Citations:    
  2. Fang A, Jacoby RJ, Beatty C, Germine L, Plessow F, Wilhelm S, Lawson EA. Serum oxytocin levels are elevated in body dysmorphic disorder and related to severity of psychopathology. Psychoneuroendocrinology. 2020 03; 113:104541. PMID: 31862613.
    Citations:    
  3. Gillan CM, Kalanthroff E, Evans M, Weingarden HM, Jacoby RJ, Gershkovich M, Snorrason I, Campeas R, Cervoni C, Crimarco NC, Sokol Y, Garnaat SL, McLaughlin NCR, Phelps EA, Pinto A, Boisseau CL, Wilhelm S, Daw ND, Simpson HB. Comparison of the Association Between Goal-Directed Planning and Self-reported Compulsivity vs Obsessive-Compulsive Disorder Diagnosis. JAMA Psychiatry. 2019 Oct 09; 1-10. PMID: 31596434.
    Citations:    
  4. Jacoby RJ, Abramowitz JS, Blakey SM, Reuman L. Is the hierarchy necessary? Gradual versus variable exposure intensity in the treatment of unacceptable obsessional thoughts. J Behav Ther Exp Psychiatry. 2019 09; 64:54-63. PMID: 30851653.
    Citations:    
  5. Blakey SM, Abramowitz JS, Buchholz JL, Jessup SC, Jacoby RJ, Reuman L, Pentel KZ. A randomized controlled trial of the judicious use of safety behaviors during exposure therapy. Behav Res Ther. 2019 01; 112:28-35. PMID: 30481681.
    Citations:    Fields:    
  6. Brennan BP, Jacoby RJ, Widge AS. A Case of Severe Intractable Contamination-Based Obsessive-Compulsive Disorder. JAMA Psychiatry. 2018 10 01; 75(10):1088-1089. PMID: 30128485.
    Citations:    Fields:    
  7. Twohig MP, Abramowitz JS, Smith BM, Fabricant LE, Jacoby RJ, Morrison KL, Bluett EJ, Reuman L, Blakey SM, Ledermann T. Adding acceptance and commitment therapy to exposure and response prevention for obsessive-compulsive disorder: A randomized controlled trial. Behav Res Ther. 2018 09; 108:1-9. PMID: 29966992.
    Citations:    Fields:    
  8. Reuman L, Jacoby RJ, Blakey SM, Riemann BC, Leonard RC, Abramowitz JS. Predictors of illness anxiety symptoms in patients with obsessive compulsive disorder. Psychiatry Res. 2017 10; 256:417-422. PMID: 28697487.
    Citations: 1     Fields:    Translation:Humans
  9. Jacoby RJ, Abramowitz JS. Inhibitory learning approaches to exposure therapy: A critical review and translation to obsessive-compulsive disorder. Clin Psychol Rev. 2016 11; 49:28-40. PMID: 27521505.
    Citations: 2     Fields:    Translation:Humans
  10. Jacoby RJ, Abramowitz JS, Reuman L, Blakey SM. Enhancing the ecological validity of the Beads Task as a behavioral measure of intolerance of uncertainty. J Anxiety Disord. 2016 06; 41:43-9. PMID: 26896872.
    Citations: 1     Fields:    Translation:Humans
  11. Wheaton MG, Abramowitz JS, Jacoby RJ, Zwerling J, Rodriguez CI. An investigation of the role of intolerance of uncertainty in hoarding symptoms. J Affect Disord. 2016 Mar 15; 193:208-14. PMID: 26773912.
    Citations:    Fields:    Translation:Humans
  12. Blakey SM, Jacoby RJ, Reuman L, Abramowitz JS. The Relative Contributions of Experiential Avoidance and Distress Tolerance to OC Symptoms. Behav Cogn Psychother. 2016 Jul; 44(4):460-71. PMID: 26639901.
    Citations: 1     Fields:    Translation:Humans
  13. Blakey SM, Reuman L, Jacoby RJ, Abramowitz JS. Tracing "Fearbola": Psychological Predictors of Anxious Responding to the Threat of Ebola. Cognit Ther Res. 2015; 39(6):816-825. PMID: 32214559.
    Citations:    
  14. Abramowitz JS, Jacoby RJ. Obsessive-compulsive and related disorders: a critical review of the new diagnostic class. Annu Rev Clin Psychol. 2015; 11:165-86. PMID: 25581239.
    Citations: 3     Fields:    Translation:Humans
  15. Jacoby RJ, Berman NC, Graziano R, Abramowitz JS. Examining Attentional Bias in Scrupulosity: Null Findings From the Dot Probe Paradigm. J Cogn Psychother. 2015; 29(4):302-314. PMID: 32755940.
    Citations:    
  16. Reuman L, Jacoby RJ, Fabricant LE, Herring B, Abramowitz JS. Uncertainty as an anxiety cue at high and low levels of threat. J Behav Ther Exp Psychiatry. 2015 Jun; 47:111-9. PMID: 25562749.
    Citations: 2     Fields:    Translation:Humans
  17. Jacoby RJ, Abramowitz JS, Buck BE, Fabricant LE. How is the Beads Task related to intolerance of uncertainty in anxiety disorders? J Anxiety Disord. 2014 Aug; 28(6):495-503. PMID: 24930046.
    Citations: 1     Fields:    Translation:Humans
  18. Jacoby RJ, Leonard RC, Riemann BC, Abramowitz JS. Predictors of quality of life and functional impairment in obsessive-compulsive disorder. Compr Psychiatry. 2014 Jul; 55(5):1195-202. PMID: 24746527.
    Citations: 4     Fields:    Translation:Humans
  19. Jacoby RJ, Fabricant LE, Leonard RC, Riemann BC, Abramowitz JS. Just to be certain: Confirming the factor structure of the intolerance of uncertainty scale in patients with obsessive-compulsive disorder. J Anxiety Disord. 2013 Jun; 27(5):535-42. PMID: 23973743.
    Citations: 4     Fields:    Translation:Humans
  20. Bui E, Orr SP, Jacoby RJ, Keshaviah A, LeBlanc NJ, Milad MR, Pollack MH, Simon NM. Two weeks of pretreatment with escitalopram facilitates extinction learning in healthy individuals. Hum Psychopharmacol. 2013 Sep; 28(5):447-56. PMID: 23776033.
    Citations: 8     Fields:    Translation:Humans
  21. Hoge EA, Marques L, Wechsler RS, Lasky AK, Delong HR, Jacoby RJ, Worthington JJ, Pollack MH, Simon NM. The role of anxiety sensitivity in sleep disturbance in panic disorder. J Anxiety Disord. 2011 May; 25(4):536-8. PMID: 21277737.
    Citations: 4     Fields:    Translation:Humans
  22. Zanarini MC, Jacoby RJ, Frankenburg FR, Reich DB, Fitzmaurice G. The 10-year course of social security disability income reported by patients with borderline personality disorder and axis II comparison subjects. J Pers Disord. 2009 Aug; 23(4):346-56. PMID: 19663655.
    Citations: 14     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.