Harvard Catalyst Profiles

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Christin Yen-Ming Sander, Ph.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R00DA043629 (SANDER, CHRISTIN Y.) Sep 30, 2019 - Aug 31, 2022
    NIH/NIDA
    Imaging dopamine receptor adaptations and signaling pathways with combined PET/fMRI
    Role: Principal Investigator
  2. K99DA043629 (SANDER, CHRISTIN Y.) Jul 15, 2017 - Jun 30, 2019
    NIH/NIDA
    Imaging dopamine receptor adaptations and signaling pathways with combined PET/fMRI
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Nyman E, Stein RR, Jing X, Wang W, Marks B, Zervantonakis IK, Korkut A, Gauthier NP, Sander C. Perturbation biology links temporal protein changes to drug responses in a melanoma cell line. PLoS Comput Biol. 2020 Jul; 16(7):e1007909. PMID: 32667922.
    Citations:    
  2. Sander CY, Hansen HD, Wey HY. Advances in simultaneous PET/MR for imaging neuroreceptor function. J Cereb Blood Flow Metab. 2020 Jun; 40(6):1148-1166. PMID: 32169011.
    Citations:    
  3. Rheinbay E, Nielsen MM, Abascal F, Wala JA, Shapira O, Tiao G, Hornshøj H, Hess JM, Juul RI, Lin Z, Feuerbach L, Sabarinathan R, Madsen T, Kim J, Mularoni L, Shuai S, Lanzós A, Herrmann C, Maruvka YE, Shen C, Amin SB, Bandopadhayay P, Bertl J, Boroevich KA, Busanovich J, Carlevaro-Fita J, Chakravarty D, Chan CWY, Craft D, Dhingra P, Diamanti K, Fonseca NA, Gonzalez-Perez A, Guo Q, Hamilton MP, Haradhvala NJ, Hong C, Isaev K, Johnson TA, Juul M, Kahles A, Kahraman A, Kim Y, Komorowski J, Kumar K, Kumar S, Lee D, Lehmann KV, Li Y, Liu EM, Lochovsky L, Park K, Pich O, Roberts ND, Saksena G, Schumacher SE, Sidiropoulos N, Sieverling L, Sinnott-Armstrong N, Stewart C, Tamborero D, Tubio JMC, Umer HM, Uusküla-Reimand L, Wadelius C, Wadi L, Yao X, Zhang CZ, Zhang J, Haber JE, Hobolth A, Imielinski M, Kellis M, Lawrence MS, von Mering C, Nakagawa H, Raphael BJ, Rubin MA, Sander C, Stein LD, Stuart JM, Tsunoda T, Wheeler DA, Johnson R, Reimand J, Gerstein M, Khurana E, Campbell PJ, López-Bigas N, Weischenfeldt J, Beroukhim R, Martincorena I, Pedersen JS, Getz G. Analyses of non-coding somatic drivers in 2,658 cancer whole genomes. Nature. 2020 02; 578(7793):102-111. PMID: 32025015.
    Citations:    
  4. Stiffler MA, Poelwijk FJ, Brock KP, Stein RR, Riesselman A, Teyra J, Sidhu SS, Marks DS, Gauthier NP, Sander C. Protein Structure from Experimental Evolution. Cell Syst. 2020 Jan 22; 10(1):15-24.e5. PMID: 31838147.
    Citations:    
  5. Rollins NJ, Brock KP, Poelwijk FJ, Stiffler MA, Gauthier NP, Sander C, Marks DS. Inferring protein 3D structure from deep mutation scans. Nat Genet. 2019 07; 51(7):1170-1176. PMID: 31209393.
    Citations:    
  6. Hopf TA, Green AG, Schubert B, Mersmann S, Schärfe CPI, Ingraham JB, Toth-Petroczy A, Brock K, Riesselman AJ, Palmedo P, Kang C, Sheridan R, Draizen EJ, Dallago C, Sander C, Marks DS. The EVcouplings Python framework for coevolutionary sequence analysis. Bioinformatics. 2019 05 01; 35(9):1582-1584. PMID: 30304492.
    Citations:    Fields:    
  7. Saito Y, Li L, Coyaud E, Luna A, Sander C, Raught B, Asara JM, Brown M, Muthuswamy SK. LLGL2 rescues nutrient stress by promoting leucine uptake in ER+ breast cancer. Nature. 2019 05; 569(7755):275-279. PMID: 30996345.
    Citations:    
  8. Sander CY, Schoenberger M, Hooker JM. Response to Comment on "In Vivo [18F]GE-179 Brain Signal Does Not Show NMDA-Specific Modulation with Drug Challenges in Rodents and Nonhuman Primates". ACS Chem Neurosci. 2019 01 16; 10(1):773-775. PMID: 30346705.
    Citations:    Fields:    
  9. Stein RR, Tanoue T, Szabady RL, Bhattarai SK, Olle B, Norman JM, Suda W, Oshima K, Hattori M, Gerber GK, Sander C, Honda K, Bucci V. Computer-guided design of optimal microbial consortia for immune system modulation. Elife. 2018 04 17; 7. PMID: 29664397.
    Citations:    Fields:    
  10. Schoenberger M, Schroeder FA, Placzek MS, Carter RL, Rosen BR, Hooker JM, Sander CY. In Vivo [18F]GE-179 Brain Signal Does Not Show NMDA-Specific Modulation with Drug Challenges in Rodents and Nonhuman Primates. ACS Chem Neurosci. 2018 02 21; 9(2):298-305. PMID: 29050469.
    Citations: 2     Fields:    Translation:AnimalsCells
  11. Hansen HD, Mandeville JB, Sander CY, Hooker JM, Catana C, Rosen BR, Knudsen GM. Functional Characterization of 5-HT1B Receptor Drugs in Nonhuman Primates Using Simultaneous PET-MR. J Neurosci. 2017 11 01; 37(44):10671-10678. PMID: 28972127.
    Citations:    Fields:    Translation:Animals
  12. Sander CY, Mandeville JB, Wey HY, Catana C, Hooker JM, Rosen BR. Effects of flow changes on radiotracer binding: Simultaneous measurement of neuroreceptor binding and cerebral blood flow modulation. J Cereb Blood Flow Metab. 2019 01; 39(1):131-146. PMID: 28816571.
    Citations: 3     Fields:    
  13. Sander CY, Hesse S. News and views on in-vivo imaging of neurotransmission using PET and MRI. Q J Nucl Med Mol Imaging. 2017 Dec; 61(4):414-428. PMID: 28750497.
    Citations:    Fields:    Translation:HumansCells
  14. Hopf TA, Ingraham JB, Poelwijk FJ, Schärfe CP, Springer M, Sander C, Marks DS. Mutation effects predicted from sequence co-variation. Nat Biotechnol. 2017 02; 35(2):128-135. PMID: 28092658.
    Citations: 30     Fields:    Translation:HumansCells
  15. Toth-Petroczy A, Palmedo P, Ingraham J, Hopf TA, Berger B, Sander C, Marks DS. Structured States of Disordered Proteins from Genomic Sequences. Cell. 2016 Sep 22; 167(1):158-170.e12. PMID: 27662088.
    Citations: 19     Fields:    Translation:HumansCells
  16. Mandeville JB, Sander CYM, Wey HY, Hooker JM, Hansen HD, Svarer C, Knudsen GM, Rosen BR. A regularized full reference tissue model for PET neuroreceptor mapping. Neuroimage. 2016 Oct 01; 139:405-414. PMID: 27364474.
    Citations:    Fields:    Translation:HumansAnimals
  17. Weinreb C, Riesselman AJ, Ingraham JB, Gross T, Sander C, Marks DS. 3D RNA and Functional Interactions from Evolutionary Couplings. Cell. 2016 May 05; 165(4):963-75. PMID: 27087444.
    Citations: 15     Fields:    Translation:Cells
  18. Sander CY, Hooker JM, Catana C, Rosen BR, Mandeville JB. Imaging Agonist-Induced D2/D3 Receptor Desensitization and Internalization In Vivo with PET/fMRI. Neuropsychopharmacology. 2016 Apr; 41(5):1427-36. PMID: 26388148.
    Citations: 8     Fields:    Translation:Animals
  19. Hayat S, Sander C, Marks DS, Elofsson A. All-atom 3D structure prediction of transmembrane ß-barrel proteins from sequences. Proc Natl Acad Sci U S A. 2015 Apr 28; 112(17):5413-8. PMID: 25858953.
    Citations: 11     Fields:    Translation:Cells
  20. Hopf TA, Schärfe CP, Rodrigues JP, Green AG, Kohlbacher O, Sander C, Bonvin AM, Marks DS. Sequence co-evolution gives 3D contacts and structures of protein complexes. Elife. 2014 Sep 25; 3. PMID: 25255213.
    Citations: 86     Fields:    Translation:Cells
  21. Michel M, Hayat S, Skwark MJ, Sander C, Marks DS, Elofsson A. PconsFold: improved contact predictions improve protein models. Bioinformatics. 2014 Sep 01; 30(17):i482-8. PMID: 25161237.
    Citations: 28     Fields:    Translation:Cells
  22. Sander CY, Keil B, Chonde DB, Rosen BR, Catana C, Wald LL. A 31-channel MR brain array coil compatible with positron emission tomography. Magn Reson Med. 2015 Jun; 73(6):2363-75. PMID: 25046699.
    Citations: 5     Fields:    Translation:Humans
  23. Villien M, Wey HY, Mandeville JB, Catana C, Polimeni JR, Sander CY, Zürcher NR, Chonde DB, Fowler JS, Rosen BR, Hooker JM. Dynamic functional imaging of brain glucose utilization using fPET-FDG. Neuroimage. 2014 Oct 15; 100:192-9. PMID: 24936683.
    Citations: 13     Fields:    Translation:HumansAnimals
  24. Li L, Shen C, Nakamura E, Ando K, Signoretti S, Beroukhim R, Cowley GS, Lizotte P, Liberzon E, Bair S, Root DE, Tamayo P, Tsherniak A, Cheng SC, Tabak B, Jacobsen A, Hakimi AA, Schultz N, Ciriello G, Sander C, Hsieh JJ, Kaelin WG. SQSTM1 is a pathogenic target of 5q copy number gains in kidney cancer. Cancer Cell. 2013 Dec 09; 24(6):738-50. PMID: 24332042.
    Citations: 36     Fields:    Translation:HumansAnimalsCells
  25. Wang C, Wilson CM, Moseley CK, Carlin SM, Hsu S, Arabasz G, Schroeder FA, Sander CY, Hooker JM. Evaluation of potential PET imaging probes for the orexin 2 receptors. Nucl Med Biol. 2013 Nov; 40(8):1000-5. PMID: 23953751.
    Citations: 4     Fields:    Translation:Animals
  26. Sander CY, Hooker JM, Catana C, Normandin MD, Alpert NM, Knudsen GM, Vanduffel W, Rosen BR, Mandeville JB. Neurovascular coupling to D2/D3 dopamine receptor occupancy using simultaneous PET/functional MRI. Proc Natl Acad Sci U S A. 2013 Jul 02; 110(27):11169-74. PMID: 23723346.
    Citations: 25     Fields:    Translation:Animals
  27. Mandeville JB, Sander CYM, Jenkins BG, Hooker JM, Catana C, Vanduffel W, Alpert NM, Rosen BR, Normandin MD. A receptor-based model for dopamine-induced fMRI signal. Neuroimage. 2013 Jul 15; 75:46-57. PMID: 23466936.
    Citations: 14     Fields:    Translation:HumansAnimals
  28. Marks DS, Hopf TA, Sander C. Protein structure prediction from sequence variation. Nat Biotechnol. 2012 Nov; 30(11):1072-80. PMID: 23138306.
    Citations: 126     Fields:    Translation:Cells
  29. Hopf TA, Colwell LJ, Sheridan R, Rost B, Sander C, Marks DS. Three-dimensional structures of membrane proteins from genomic sequencing. Cell. 2012 Jun 22; 149(7):1607-21. PMID: 22579045.
    Citations: 139     Fields:    Translation:HumansAnimalsCells
  30. Marks DS, Colwell LJ, Sheridan R, Hopf TA, Pagnani A, Zecchina R, Sander C. Protein 3D structure computed from evolutionary sequence variation. PLoS One. 2011; 6(12):e28766. PMID: 22163331.
    Citations: 223     Fields:    Translation:HumansAnimalsCells
  31. Barretina J, Taylor BS, Banerji S, Ramos AH, Lagos-Quintana M, Decarolis PL, Shah K, Socci ND, Weir BA, Ho A, Chiang DY, Reva B, Mermel CH, Getz G, Antipin Y, Beroukhim R, Major JE, Hatton C, Nicoletti R, Hanna M, Sharpe T, Fennell TJ, Cibulskis K, Onofrio RC, Saito T, Shukla N, Lau C, Nelander S, Silver SJ, Sougnez C, Viale A, Winckler W, Maki RG, Garraway LA, Lash A, Greulich H, Root DE, Sellers WR, Schwartz GK, Antonescu CR, Lander ES, Varmus HE, Ladanyi M, Sander C, Meyerson M, Singer S. Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy. Nat Genet. 2010 Aug; 42(8):715-21. PMID: 20601955.
    Citations: 215     Fields:    Translation:Humans
  32. Mathew JP, Taylor BS, Bader GD, Pyarajan S, Antoniotti M, Chinnaiyan AM, Sander C, Burakoff SJ, Mishra B. From bytes to bedside: data integration and computational biology for translational cancer research. PLoS Comput Biol. 2007 Feb 23; 3(2):e12. PMID: 17319736.
    Citations: 23     Fields:    
  33. Monticelli S, Ansel KM, Xiao C, Socci ND, Krichevsky AM, Thai TH, Rajewsky N, Marks DS, Sander C, Rajewsky K, Rao A, Kosik KS. MicroRNA profiling of the murine hematopoietic system. Genome Biol. 2005; 6(8):R71. PMID: 16086853.
    Citations: 148     Fields:    Translation:Animals
  34. Berriz GF, King OD, Bryant B, Sander C, Roth FP. Characterizing gene sets with FuncAssociate. Bioinformatics. 2003 Dec 12; 19(18):2502-4. PMID: 14668247.
    Citations: 158     Fields:    Translation:Animals
  35. Vitkup D, Sander C, Church GM. The amino-acid mutational spectrum of human genetic disease. Genome Biol. 2003; 4(11):R72. PMID: 14611658.
    Citations: 57     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.