Harvard Catalyst Profiles

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Paul James Hoover, M.D.,Ph.D.

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Biography
Broad Institute, Cambridge, MaPost-doctoral research (Nir Hacohen)
Brigham & Women's Hospital, Boston, MaInternship, Residency, Rheumatology Fellowship
Stanford School of Medicine, Stanford, CaMD, PhD
2024 - 2028
Career Development Award
Investigator Award
Master Class in Lupus Basic and Clinical Sciences
Clinical Fellow Teaching Award
Medical Scientist Training Program Fellowship
Phi Beta Kappa
Summa cum laude

Overview
Dr. Hoover is a dedicated rheumatologist and translational physician-scientist specializing in the treatment and laboratory-based investigations of autoimmune diseases. As the Director of Translational Research in Lupus Nephritis at Brigham and Women's Hospital, he leads studies on the immune responses and the role of macrophages that contribute to tissue damage and repair in the kidneys and other organs affected by lupus and related autoimmune conditions. His lab employs advanced methodologies, including single-cell analyses, spatial technologies, and genomic perturbation strategies, utilizing both human samples and mouse models of disease. Dr. Hoover earned his medical degree and doctorate in molecular and cellular physiology from Stanford University School of Medicine. He completed his residency and fellowship in Rheumatology at Brigham and Women's Hospital and conducted postdoctoral research at the Broad Institute of MIT and Harvard.

Bibliographic
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.