Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

David Eiichi Kozono, M.D.,Ph.D.

Title
Institution
Department
Address
Phone
Fax
Profile Picture

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Kehl KL, Zahrieh D, Yang P, Hillman SL, Tan AD, Sands JM, Oxnard GR, Gillaspie EA, Wigle D, Malik S, Stinchcombe TE, Ramalingam SS, Kelly K, Govindan R, Mandrekar SJ, Osarogiagbon RU, Kozono D. Rates of Guideline-Concordant Surgery and Adjuvant Chemotherapy Among Patients With Early-Stage Lung Cancer in the US ALCHEMIST Study (Alliance A151216). JAMA Oncol. 2022 Mar 17. PMID: 35297944.
    Citations:    Fields:    
  2. Fendler W, Tomasik B, Atkins K, Stawiski K, Chalubinska-Fendler J, Kozono D. The clinician's guide to radiotherapy complications. Pol Arch Intern Med. 2022 01 28; 132(1). PMID: 35089673.
    Citations:    Fields:    Translation:Humans
  3. Atkins KM, Weiss J, Zeleznik R, Bitterman DS, Chaunzwa TL, Huynh E, Guthier C, Kozono DE, Lewis JH, Tamarappoo BK, Nohria A, Hoffmann U, Aerts HJWL, Mak RH. Elevated Coronary Artery Calcium Quantified by a Validated Deep Learning Model From Lung Cancer Radiotherapy Planning Scans Predicts Mortality. JCO Clin Cancer Inform. 2022 Jan; 6:e2100095. PMID: 35084935.
    Citations:    Fields:    
  4. Bitterman DS, Selesnick P, Bredfeldt J, Williams CL, Guthier C, Huynh E, Kozono DE, Lewis JH, Cormack RA, Carpenter CM, Mak RH, Atkins KM. Dosimetric Planning Tradeoffs to Reduce Heart Dose Using Machine Learning-Guided Decision Support Software in Patients with Lung Cancer. Int J Radiat Oncol Biol Phys. 2022 03 15; 112(4):996-1003. PMID: 34774998.
    Citations:    Fields:    Translation:Humans
  5. Liu KX, Sierra-Davidson K, Tyan K, Orlina LT, Marcoux JP, Kann BH, Kozono DE, Mak RH, White A, Singer L. Surgical complications and clinical outcomes after dose-escalated trimodality therapy for non-small cell lung cancer in the era of intensity-modulated radiotherapy. Radiother Oncol. 2021 12; 165:44-51. PMID: 34695520.
    Citations:    Fields:    Translation:Humans
  6. Meerman M, Driessen R, van Engeland NCA, Bergsma I, Steenhuijsen JLG, Kozono D, Aikawa E, Hjortnaes J, Bouten CVC. Radiation Induces Valvular Interstitial Cell Calcific Response in an in vitro Model of Calcific Aortic Valve Disease. Front Cardiovasc Med. 2021; 8:687885. PMID: 34527708.
    Citations:    
  7. Kozono DE, Stinchcombe TE, Salama JK, Bogart J, Petty WJ, Guarino MJ, Bazhenova L, Larner JM, Weiss J, DiPetrillo TA, Feigenberg SJ, Chen X, Sun Z, Nuthalapati S, Rosenwinkel L, Johnson EF, Bach BA, Luo Y, Vokes EE. Veliparib in combination with carboplatin/paclitaxel-based chemoradiotherapy in patients with stage III non-small cell lung cancer. Lung Cancer. 2021 09; 159:56-65. PMID: 34311345.
    Citations: 1     Fields:    Translation:Humans
  8. Hensing TA, Wang X, Stinchcombe TE, Gao J, Knopp MV, Watson M, Dudek AZ, Graziano SL, Patel JD, Faller BA, Dragnev KH, Kozono D, Vokes EE. Alliance Foundation Trial 09: A Randomized, Multicenter, Phase 2 Trial Evaluating Two Sequences of Pembrolizumab and Standard Platinum-Based Chemotherapy in Patients With Metastatic NSCLC. JTO Clin Res Rep. 2021 Aug; 2(8):100208. PMID: 34590049.
    Citations:    
  9. Talcott WJ, Miccio JA, Park HS, White AA, Kozono DE, Singer L, Sands JM, Sholl LM, Detterbeck FC, Mak RH, Decker RH, Kann BH. Rates of invasive disease and outcomes in NSCLC patients with biopsy suggestive of carcinoma in situ. Lung Cancer. 2021 07; 157:17-20. PMID: 34052704.
    Citations:    Fields:    Translation:Humans
  10. Sands JM, Mandrekar SJ, Kozono D, Oxnard GR, Hillman SL, Wigle DA, Govindan R, Carlisle J, Gray J, Salama JK, Raez L, Ganti A, Foster N, Malik S, Bradley J, Kelly K, Ramalingam SS, Stinchcombe TE. Integration of immunotherapy into adjuvant therapy for resected non-small-cell lung cancer: ALCHEMIST chemo-IO (ACCIO). Immunotherapy. 2021 06; 13(9):727-734. PMID: 33878954.
    Citations: 2     Fields:    Translation:HumansCTClinical Trials
  11. Atkins KM, Bitterman DS, Chaunzwa TL, Kozono DE, Baldini EH, Aerts HJWL, Tamarappoo BK, Hoffmann U, Nohria A, Mak RH. Mean Heart Dose Is an Inadequate Surrogate for Left Anterior Descending Coronary Artery Dose and the Risk of Major Adverse Cardiac Events in Lung Cancer Radiation Therapy. Int J Radiat Oncol Biol Phys. 2021 08 01; 110(5):1473-1479. PMID: 33713743.
    Citations: 1     Fields:    Translation:Humans
  12. Branigan TB, Kozono D, Schade AE, Deraska P, Rivas HG, Sambel L, Reavis HD, Shapiro GI, D'Andrea AD, DeCaprio JA. MMB-FOXM1-driven premature mitosis is required for CHK1 inhibitor sensitivity. Cell Rep. 2021 03 02; 34(9):108808. PMID: 33657372.
    Citations: 7     Fields:    Translation:HumansCells
  13. Atkins KM, Chaunzwa TL, Lamba N, Bitterman DS, Rawal B, Bredfeldt J, Williams CL, Kozono DE, Baldini EH, Nohria A, Hoffmann U, Aerts HJWL, Mak RH. Association of Left Anterior Descending Coronary Artery Radiation Dose With Major Adverse Cardiac Events and Mortality in Patients With Non-Small Cell Lung Cancer. JAMA Oncol. 2021 02 01; 7(2):206-219. PMID: 33331883.
    Citations: 9     Fields:    Translation:Humans
  14. Atkins KM, Bitterman DS, Chaunzwa TL, Williams CL, Rahman R, Kozono DE, Baldini EH, Aerts HJWL, Tamarappoo BK, Hoffmann U, Nohria A, Mak RH. Statin Use, Heart Radiation Dose, and Survival in Locally Advanced Lung Cancer. Pract Radiat Oncol. 2021 Sep-Oct; 11(5):e459-e467. PMID: 33476841.
    Citations: 1     Fields:    Translation:Humans
  15. Li F, Kozono D, Deraska P, Branigan T, Dunn C, Zheng XF, Parmar K, Nguyen H, DeCaprio J, Shapiro GI, Chowdhury D, D'Andrea AD. CHK1 Inhibitor Blocks Phosphorylation of FAM122A and Promotes Replication Stress. Mol Cell. 2020 11 05; 80(3):410-422.e6. PMID: 33108758.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  16. Liu KX, Chen YH, Kozono D, Mak RH, Boyle PJ, Janeway KA, Mullen EA, Marcus KJ. Phase I/II Study of Stereotactic Body Radiation Therapy for Pulmonary Metastases in Pediatric Patients. Adv Radiat Oncol. 2020 Nov-Dec; 5(6):1267-1273. PMID: 33305087.
    Citations: 2     
  17. Mueller R, Yasmin-Karim S, DeCosmo K, Vazquez-Pagan A, Sridhar S, Kozono D, Hesser J, Ngwa W. Increased carcinoembryonic antigen expression on the surface of lung cancer cells using gold nanoparticles during radiotherapy. Phys Med. 2020 Aug; 76:236-242. PMID: 32731132.
    Citations: 1     Fields:    Translation:Humans
  18. Herter-Sprie GS, Korideck H, Christensen CL, Herter JM, Rhee K, Berbeco RI, Bennett DG, Akbay EA, Kozono D, Mak RH, Makrigiorgos GM, Kimmelman AC, Wong KK. Author Correction: Image-guided radiotherapy platform using single nodule conditional lung cancer mouse models. Nat Commun. 2020 Apr 09; 11(1):1835. PMID: 32273495.
    Citations:    Fields:    
  19. Cai MY, Dunn CE, Chen W, Kochupurakkal BS, Nguyen H, Moreau LA, Shapiro GI, Parmar K, Kozono D, D'Andrea AD. Cooperation of the ATM and Fanconi Anemia/BRCA Pathways in Double-Strand Break End Resection. Cell Rep. 2020 02 18; 30(7):2402-2415.e5. PMID: 32075772.
    Citations: 12     Fields:    Translation:HumansCells
  20. Kamran SC, Coroller T, Milani N, Agrawal V, Baldini EH, Chen AB, Johnson BE, Kozono D, Franco I, Chopra N, Zeleznik R, Aerts HJWL, Mak R. The impact of quantitative CT-based tumor volumetric features on the outcomes of patients with limited stage small cell lung cancer. Radiat Oncol. 2020 Jan 14; 15(1):14. PMID: 31937336.
    Citations: 1     Fields:    Translation:Humans
  21. Mitra D, Chen YH, Li R, Hermann G, Atkins K, Kozono D, Baldini EH, Aizer A, Chukwueke U, Mak RH. EGFR mutant locally advanced non-small cell lung cancer is at increased risk of brain metastasis. Clin Transl Radiat Oncol. 2019 Sep; 18:32-38. PMID: 31341973.
    Citations: 3     
  22. Atkins KM, Rawal B, Chaunzwa TL, Lamba N, Bitterman DS, Williams CL, Kozono DE, Baldini EH, Chen AB, Nguyen PL, D'Amico AV, Nohria A, Hoffmann U, Aerts HJWL, Mak RH. Cardiac Radiation Dose, Cardiac Disease, and Mortality in Patients With Lung Cancer. J Am Coll Cardiol. 2019 06 18; 73(23):2976-2987. PMID: 31196455.
    Citations: 40     Fields:    Translation:HumansPHPublic Health
  23. Chalubinska-Fendler J, Graczyk L, Piotrowski G, Wyka K, Nowicka Z, Tomasik B, Fijuth J, Kozono D, Fendler W. Lipopolysaccharide-Binding Protein Is an Early Biomarker of Cardiac Function After Radiation Therapy for Breast Cancer. Int J Radiat Oncol Biol Phys. 2019 08 01; 104(5):1074-1083. PMID: 30991100.
    Citations: 4     Fields:    Translation:HumansPHPublic Health
  24. Lim KS, Li H, Roberts EA, Gaudiano EF, Clairmont C, Sambel LA, Ponnienselvan K, Liu JC, Yang C, Kozono D, Parmar K, Yusufzai T, Zheng N, D'Andrea AD. USP1 Is Required for Replication Fork Protection in BRCA1-Deficient Tumors. Mol Cell. 2018 12 20; 72(6):925-941.e4. PMID: 30576655.
    Citations: 31     Fields:    Translation:HumansAnimalsCells
  25. Ishizuka JJ, Manguso RT, Cheruiyot CK, Bi K, Panda A, Iracheta-Vellve A, Miller BC, Du PP, Yates KB, Dubrot J, Buchumenski I, Comstock DE, Brown FD, Ayer A, Kohnle IC, Pope HW, Zimmer MD, Sen DR, Lane-Reticker SK, Robitschek EJ, Griffin GK, Collins NB, Long AH, Doench JG, Kozono D, Levanon EY, Haining WN. Loss of ADAR1 in tumours overcomes resistance to immune checkpoint blockade. Nature. 2019 01; 565(7737):43-48. PMID: 30559380.
    Citations: 146     Fields:    Translation:AnimalsCells
  26. Mak RH, Hermann G, Aerts HJ, Baldini EH, Chen AB, Kozono D, Rabin MS, Swanson SJ, Chen YH, Catalano P, Johnson BE, Jänne PA. Outcomes by EGFR, KRAS, and ALK Genotype After Combined Modality Therapy for Locally Advanced Non-Small-Cell Lung Cancer. JCO Precis Oncol. 2018 Nov; 2:1-18. PMID: 35135121.
    Citations:    Fields:    
  27. Hou Y, Hermann G, Lewis JH, Aerts HJ, Baldini EH, Chen AB, Colson YL, Hacker FL, Killoran JH, Kozono DE, Wagar M, Wee JO, Mak RH. Clinical Outcomes After Lung Stereotactic Body Radiation Therapy in Patients With or Without a Prior Lung Resection. Am J Clin Oncol. 2018 07; 41(7):695-701. PMID: 27819875.
    Citations: 4     Fields:    Translation:Humans
  28. Pal S, Kozono D, Yang X, Fendler W, Fitts W, Ni J, Alberta JA, Zhao J, Liu KX, Bian J, Truffaux N, Weiss WA, Resnick AC, Bandopadhayay P, Ligon KL, DuBois SG, Mueller S, Chowdhury D, Haas-Kogan DA. Dual HDAC and PI3K Inhibition Abrogates NF?B- and FOXM1-Mediated DNA Damage Response to Radiosensitize Pediatric High-Grade Gliomas. Cancer Res. 2018 07 15; 78(14):4007-4021. PMID: 29760046.
    Citations: 28     Fields:    Translation:HumansAnimalsCells
  29. Deraska PV, O'Leary C, Reavis HD, Labe S, Dinh TK, Lazaro JB, Sweeney C, D'Andrea AD, Kozono D. NF-?B inhibition by dimethylaminoparthenolide radiosensitizes non-small-cell lung carcinoma by blocking DNA double-strand break repair. Cell Death Discov. 2018 Dec; 4:10. PMID: 29531807.
    Citations: 7     
  30. Diao K, Chen YH, Catalano PJ, Lee S, Milani N, Killoran JH, Baldini EH, Chen AB, Kozono DE, Mak RH. Radiation toxicity in patients with collagen vascular disease and intrathoracic malignancy treated with modern radiation techniques. Radiother Oncol. 2017 11; 125(2):301-309. PMID: 29102264.
    Citations: 3     Fields:    Translation:Humans
  31. Franco I, Chen YH, Chipidza F, Agrawal V, Romano J, Baldini E, Chen A, Colson Y, Hou Y, Kozono D, Wee J, Mak R. Use of frailty to predict survival in elderly patients with early stage non-small-cell lung cancer treated with stereotactic body radiation therapy. J Geriatr Oncol. 2018 03; 9(2):130-137. PMID: 28941581.
    Citations: 7     Fields:    Translation:Humans
  32. Agrawal V, Coroller TP, Hou Y, Lee SW, Romano JL, Baldini EH, Chen AB, Kozono D, Swanson SJ, Wee JO, Aerts HJWL, Mak RH. Lymph node volume predicts survival but not nodal clearance in Stage IIIA-IIIB NSCLC. PLoS One. 2017; 12(4):e0174268. PMID: 28426673.
    Citations: 2     Fields:    Translation:Humans
  33. Agrawal V, Coroller TP, Hou Y, Lee SW, Romano JL, Baldini EH, Chen AB, Jackman DM, Kozono D, Swanson SJ, Wee JO, Aerts HJ, Mak RH. Radiologic-pathologic correlation of response to chemoradiation in resectable locally advanced NSCLC. Lung Cancer. 2016 12; 102:1-8. PMID: 27987576.
    Citations: 8     Fields:    Translation:Humans
  34. Hou Y, Lee S, Agrawal V, Romano J, Baldini EH, Chen AB, Kozono DE, Killoran JH, Wagar M, Hacker FL, Aerts HJ, Lewis JH, Mak RH. Inter-scan and inter-observer tumour volume delineation variability on cone beam computed tomography in patients treated with stereotactic body radiation therapy for early-stage non-small cell lung cancer. J Med Imaging Radiat Oncol. 2017 Feb; 61(1):93-98. PMID: 27709803.
    Citations:    Fields:    Translation:Humans
  35. Kais Z, Rondinelli B, Holmes A, O'Leary C, Kozono D, D'Andrea AD, Ceccaldi R. FANCD2 Maintains Fork Stability in BRCA1/2-Deficient Tumors and Promotes Alternative End-Joining DNA Repair. Cell Rep. 2016 06 14; 15(11):2488-99. PMID: 27264184.
    Citations: 63     Fields:    Translation:HumansAnimalsCells
  36. Dinh TK, Fendler W, Chalubinska-Fendler J, Acharya SS, O'Leary C, Deraska PV, D'Andrea AD, Chowdhury D, Kozono D. Circulating miR-29a and miR-150 correlate with delivered dose during thoracic radiation therapy for non-small cell lung cancer. Radiat Oncol. 2016 Apr 27; 11:61. PMID: 27117590.
    Citations: 43     Fields:    Translation:HumansCells
  37. Zhang H, Kozono DE, O'Connor KW, Vidal-Cardenas S, Rousseau A, Hamilton A, Moreau L, Gaudiano EF, Greenberger J, Bagby G, Soulier J, Grompe M, Parmar K, D'Andrea AD. TGF-ß Inhibition Rescues Hematopoietic Stem Cell Defects and Bone Marrow Failure in Fanconi Anemia. Cell Stem Cell. 2016 05 05; 18(5):668-81. PMID: 27053300.
    Citations: 68     Fields:    Translation:HumansAnimalsCells
  38. Li R, Hermann G, Baldini E, Chen A, Jackman D, Kozono D, Nguyen P, Nohria A, Powell G, Mak R. Advanced nodal stage predicts venous thromboembolism in patients with locally advanced non-small cell lung cancer. Lung Cancer. 2016 06; 96:41-7. PMID: 27133748.
    Citations: 10     Fields:    Translation:Humans
  39. Mingos M, Howard S, Giacalone N, Kozono D, Jacene H. Systemic Immune Response to Vaccination on FDG-PET/CT. Nucl Med Mol Imaging. 2016 Dec; 50(4):358-361. PMID: 27994693.
    Citations: 9     
  40. Kozono D, Li J, Nitta M, Sampetrean O, Gonda D, Kushwaha DS, Merzon D, Ramakrishnan V, Zhu S, Zhu K, Matsui H, Harismendy O, Hua W, Mao Y, Kwon CH, Saya H, Nakano I, Pizzo DP, VandenBerg SR, Chen CC. Dynamic epigenetic regulation of glioblastoma tumorigenicity through LSD1 modulation of MYC expression. Proc Natl Acad Sci U S A. 2015 Jul 28; 112(30):E4055-64. PMID: 26159421.
    Citations: 27     Fields:    Translation:HumansAnimalsCells
  41. Hou Y, Aileen C, Kozono D, Killoran J, Wagar M, Lee S, Hacker F, Aerts H, Lewis J, Mak R. SU-E-J-266: Cone Beam Computed Tomography (CBCT) Inter-Scan and Inter-Observer Tumor Volume Variability Assessment in Patients Treated with Stereotactic Body Radiation Therapy (SBRT) for Early Stage Non-Small Cell Lung Cancer (NSCLC). Med Phys. 2015 Jun; 42(6):3328. PMID: 26127657.
    Citations:    
  42. Baldini EH, Richards WG, Gill RR, Goodman BM, Winfrey OK, Eisen HM, Mak RH, Chen AB, Kozono DE, Bueno R, Sugarbaker DJ. Updated patterns of failure after multimodality therapy for malignant pleural mesothelioma. J Thorac Cardiovasc Surg. 2015 May; 149(5):1374-81. PMID: 25772281.
    Citations: 26     Fields:    Translation:Humans
  43. Kushwaha D, O'Leary C, Cron KR, Deraska P, Zhu K, D'Andrea AD, Kozono D. USP9X inhibition promotes radiation-induced apoptosis in non-small cell lung cancer cells expressing mid-to-high MCL1. Cancer Biol Ther. 2015; 16(3):392-401. PMID: 25692226.
    Citations: 17     Fields:    Translation:HumansCells
  44. Herter-Sprie GS, Korideck H, Christensen CL, Herter JM, Rhee K, Berbeco RI, Bennett DG, Akbay EA, Kozono D, Mak RH, Mike Makrigiorgos G, Kimmelman AC, Wong KK. Image-guided radiotherapy platform using single nodule conditional lung cancer mouse models. Nat Commun. 2014 Dec 18; 5:5870. PMID: 25519892.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  45. Mak RH, Hermann G, Lewis JH, Aerts HJ, Baldini EH, Chen AB, Colson YL, Hacker FH, Kozono D, Wee JO, Chen YH, Catalano PJ, Wong KK, Sher DJ. Outcomes by tumor histology and KRAS mutation status after lung stereotactic body radiation therapy for early-stage non-small-cell lung cancer. Clin Lung Cancer. 2015 Jan; 16(1):24-32. PMID: 25450872.
    Citations: 33     Fields:    Translation:Humans
  46. Gray PJ, Mak RH, Yeap BY, Cryer SK, Pinnell NE, Christianson LW, Sher DJ, Arvold ND, Baldini EH, Chen AB, Kozono DE, Swanson SJ, Jackman DM, Alexander BM. Aggressive therapy for patients with non-small cell lung carcinoma and synchronous brain-only oligometastatic disease is associated with long-term survival. Lung Cancer. 2014 Aug; 85(2):239-44. PMID: 24974152.
    Citations: 34     Fields:    Translation:Humans
  47. Parikh RB, Cronin AM, Kozono DE, Oxnard GR, Mak RH, Jackman DM, Lo PC, Baldini EH, Johnson BE, Chen AB. Definitive primary therapy in patients presenting with oligometastatic non-small cell lung cancer. Int J Radiat Oncol Biol Phys. 2014 Jul 15; 89(4):880-7. PMID: 24867533.
    Citations: 52     Fields:    Translation:Humans
  48. Coroller TP, Mak RH, Lewis JH, Baldini EH, Chen AB, Colson YL, Hacker FL, Hermann G, Kozono D, Mannarino E, Molodowitch C, Wee JO, Sher DJ, Killoran JH. Low incidence of chest wall pain with a risk-adapted lung stereotactic body radiation therapy approach using three or five fractions based on chest wall dosimetry. PLoS One. 2014; 9(4):e94859. PMID: 24728448.
    Citations: 12     Fields:    Translation:Humans
  49. Li J, Zhu S, Kozono D, Ng K, Futalan D, Shen Y, Akers JC, Steed T, Kushwaha D, Schlabach M, Carter BS, Kwon CH, Furnari F, Cavenee W, Elledge S, Chen CC. Genome-wide shRNA screen revealed integrated mitogenic signaling between dopamine receptor D2 (DRD2) and epidermal growth factor receptor (EGFR) in glioblastoma. Oncotarget. 2014 Feb 28; 5(4):882-93. PMID: 24658464.
    Citations: 69     Fields:    Translation:HumansAnimalsCells
  50. Gazula A, Baldini EH, Chen A, Kozono D. Comparison of once and twice daily radiotherapy for limited stage small-cell lung cancer. Lung. 2014 Feb; 192(1):151-8. PMID: 24162870.
    Citations: 10     Fields:    Translation:Humans
  51. Cron KR, Zhu K, Kushwaha DS, Hsieh G, Merzon D, Rameseder J, Chen CC, D'Andrea AD, Kozono D. Proteasome inhibitors block DNA repair and radiosensitize non-small cell lung cancer. PLoS One. 2013; 8(9):e73710. PMID: 24040035.
    Citations: 29     Fields:    Translation:HumansAnimalsCells
  52. Coroller T, Lewis J, Mak R, Chen A, Hacker F, Kozono D, Mannarino E, Molodowitch C, Killoran J. SU-E-T-694: Correlation Between Geometric Information and Dose Fractionation in Lung SBRT Treatment Plans. Med Phys. 2013 Jun; 40(6Part21):365-366. PMID: 28519454.
    Citations:    
  53. Morgan EA, Kozono DE, Wang Q, Mery CM, Butrynski JE, Baldini EH, George S, Nascimento AF, Raut CP. Cutaneous radiation-associated angiosarcoma of the breast: poor prognosis in a rare secondary malignancy. Ann Surg Oncol. 2012 Nov; 19(12):3801-8. PMID: 22890593.
    Citations: 19     Fields:    Translation:Humans
  54. Lewis J, Mak R, Molodowitch C, Mannarino E, Baldini E, Chen A, Kozono D, Sher D, Hacker F, Killoran J. TU-E-BRB-02: A Decision Support Tool for SBRT Planning Using a Searchable DVH Database. Med Phys. 2012 Jun; 39(6Part24):3908. PMID: 28518686.
    Citations:    Fields:    
  55. Kang J, D'Andrea AD, Kozono D. A DNA repair pathway-focused score for prediction of outcomes in ovarian cancer treated with platinum-based chemotherapy. J Natl Cancer Inst. 2012 May 02; 104(9):670-81. PMID: 22505474.
    Citations: 78     Fields:    Translation:HumansCells
  56. Nehs MA, Lin CI, Kozono DE, Whang EE, Cho NL, Zhu K, Moalem J, Moore FD, Ruan DT. Necroptosis is a novel mechanism of radiation-induced cell death in anaplastic thyroid and adrenocortical cancers. Surgery. 2011 Dec; 150(6):1032-9. PMID: 22136818.
    Citations: 51     Fields:    Translation:HumansCells
  57. Sturla LM, Zinn PO, Ng K, Nitta M, Kozono D, Chen CC, Kasper EM. Src homology domain-containing phosphatase 2 suppresses cellular senescence in glioblastoma. Br J Cancer. 2011 Oct 11; 105(8):1235-43. PMID: 21934682.
    Citations: 8     Fields:    Translation:HumansCells
  58. Nitta M, Kozono D, Kennedy R, Stommel J, Ng K, Zinn PO, Kushwaha D, Kesari S, Inda MM, Wykosky J, Furnari F, Hoadley KA, Chin L, DePinho RA, Cavenee WK, D'Andrea A, Chen CC. Targeting EGFR induced oxidative stress by PARP1 inhibition in glioblastoma therapy. PLoS One. 2010 May 24; 5(5):e10767. PMID: 20532243.
    Citations: 36     Fields:    Translation:HumansCells
  59. Kahle KT, Kozono D, Ng K, Hsieh G, Zinn PO, Nitta M, Chen CC. Functional genomics to explore cancer cell vulnerabilities. Neurosurg Focus. 2010 Jan; 28(1):E5. PMID: 20043720.
    Citations: 3     Fields:    Translation:HumansCells
  60. Lee JK, Kozono D, Remis J, Kitagawa Y, Agre P, Stroud RM. Structural basis for conductance by the archaeal aquaporin AqpM at 1.68 A. Proc Natl Acad Sci U S A. 2005 Dec 27; 102(52):18932-7. PMID: 16361443.
    Citations: 63     Fields:    Translation:Cells
  61. Palanivelu DV, Kozono DE, Engel A, Suda K, Lustig A, Agre P, Schirmer T. Co-axial association of recombinant eye lens aquaporin-0 observed in loosely packed 3D crystals. J Mol Biol. 2006 Jan 27; 355(4):605-11. PMID: 16309700.
    Citations: 14     Fields:    Translation:AnimalsCells
  62. Liu K, Kozono D, Kato Y, Agre P, Hazama A, Yasui M. Conversion of aquaporin 6 from an anion channel to a water-selective channel by a single amino acid substitution. Proc Natl Acad Sci U S A. 2005 Feb 08; 102(6):2192-7. PMID: 15671159.
    Citations: 23     Fields:    Translation:HumansAnimalsCells
  63. King LS, Kozono D, Agre P. From structure to disease: the evolving tale of aquaporin biology. Nat Rev Mol Cell Biol. 2004 Sep; 5(9):687-98. PMID: 15340377.
    Citations: 273     Fields:    Translation:HumansAnimalsCells
  64. Agre P, Kozono D. Aquaporin water channels: molecular mechanisms for human diseases. FEBS Lett. 2003 Nov 27; 555(1):72-8. PMID: 14630322.
    Citations: 137     Fields:    Translation:HumansCells
  65. Carbrey JM, Gorelick-Feldman DA, Kozono D, Praetorius J, Nielsen S, Agre P. Aquaglyceroporin AQP9: solute permeation and metabolic control of expression in liver. Proc Natl Acad Sci U S A. 2003 Mar 04; 100(5):2945-50. PMID: 12594337.
    Citations: 87     Fields:    Translation:AnimalsCells
  66. Kozono D, Ding X, Iwasaki I, Meng X, Kamagata Y, Agre P, Kitagawa Y. Functional expression and characterization of an archaeal aquaporin. AqpM from methanothermobacter marburgensis. J Biol Chem. 2003 Mar 21; 278(12):10649-56. PMID: 12519768.
    Citations: 31     Fields:    Translation:AnimalsCells
  67. Ikeda M, Beitz E, Kozono D, Guggino WB, Agre P, Yasui M. Characterization of aquaporin-6 as a nitrate channel in mammalian cells. Requirement of pore-lining residue threonine 63. J Biol Chem. 2002 Oct 18; 277(42):39873-9. PMID: 12177001.
    Citations: 68     Fields:    Translation:HumansAnimalsCells
  68. Kozono D, Yasui M, King LS, Agre P. Aquaporin water channels: atomic structure molecular dynamics meet clinical medicine. J Clin Invest. 2002 Jun; 109(11):1395-9. PMID: 12045251.
    Citations: 56     Fields:    Translation:HumansAnimalsCells
  69. Hazama A, Kozono D, Guggino WB, Agre P, Yasui M. Ion permeation of AQP6 water channel protein. Single channel recordings after Hg2+ activation. J Biol Chem. 2002 Aug 09; 277(32):29224-30. PMID: 12034750.
    Citations: 26     Fields:    Translation:AnimalsCells
  70. Saparov SM, Kozono D, Rothe U, Agre P, Pohl P. Water and ion permeation of aquaporin-1 in planar lipid bilayers. Major differences in structural determinants and stoichiometry. J Biol Chem. 2001 Aug 24; 276(34):31515-20. PMID: 11410596.
    Citations: 38     Fields:    Translation:HumansCells
  71. Borgnia MJ, Kozono D, Calamita G, Maloney PC, Agre P. Functional reconstitution and characterization of AqpZ, the E. coli water channel protein. J Mol Biol. 1999 Sep 03; 291(5):1169-79. PMID: 10518952.
    Citations: 70     Fields:    Translation:Cells
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact contactcatalyst.harvard.edu. For faculty or fellow appointment updates and changes, please ask your appointing department to contact HMS. For fellow personal and demographic information, contact HMS Human Resources at human_resourceshms.harvard.edu. For faculty personal and demographic information, contact HMS Office for Faculty Affairs at facappthms.harvard.edu.
Kozono's Networks
Click the
Explore
buttons for more information and interactive visualizations!
Concepts (369)
Explore
_
Co-Authors (81)
Explore
_
Similar People (60)
Explore
_
Same Department 
Explore
_
Physical Neighbors
_
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.