Harvard Catalyst Profiles

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Kent William Mouw, M.D., Ph.D.

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Mentoring
Available: 04/05/22, Expires: 06/01/23

The Mouw Lab is a basic and translational research laboratory located in the Department of Radiation Oncology at the Dana-Farber Cancer Institute, Brigham & Women's Hospital, and Harvard Medical School in Boston, MA. We are a team of cancer biologists and oncologists who are using genomic and functional approaches to study the role of DNA repair pathway alterations in tumor biology. We aim to discover novel DNA repair-directed therapies and identify biomarkers that can guide the use of existing DNA damaging agents (such as radiation and conventional chemotherapy) as well as targeted agents.


Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01CA289304 (MOUW, KENT W) May 1, 2024 - Apr 30, 2029
    NIH
    Dissecting and Targeting MAPK - PPARG Crosstalk in Bladder Cancer
    Role: Principal Investigator
  2. R01CA279221 (VAN ALLEN, ELIEZER M) Apr 1, 2024 - Mar 31, 2029
    NIH
    Dissecting Integrated Cellular Programs Promoting Platinum Resistance and Progression in Bladder Cancer
    Role: Co-Principal Investigator
  3. R21CA288234 (MOUW, KENT W) Apr 1, 2024 - Mar 31, 2026
    NIH
    Investigating Interactions Between Radiation and Antibody-Drug Conjugates in Bladder Cancer
    Role: Principal Investigator
  4. R01CA272657 (MOUW, KENT W) Sep 22, 2022 - Aug 31, 2027
    NIH
    Targeting Nucleotide Excision Repair Deficiency to Improve Bladder Sparing Treatment for Muscle Invasive Bladder Cancer
    Role: Principal Investigator
  5. R21CA263130 (MOUW, KENT W ;VISWANATHAN, SRINIVAS RAGHAVAN) Jul 1, 2021 - Jun 30, 2023
    NIH
    Targeting the DNA Damage Response in CDK12-Mutant Prostate Cancer
    Role: Principal Investigator

Bibliographic
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.