Harvard Catalyst Profiles

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Nitya Jain, Ph.D.

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The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R21AI153548 (JAIN, NITYA) Jun 22, 2020 - May 31, 2022
    Deciphering the role of IGF2BP3 in early life T cell development
    Role: Principal Investigator
  2. R01AI154626 (JAIN, NITYA) Jun 12, 2020 - May 31, 2023
    Maternal Microbial Influences on Early-life Thymic T cell development
    Role: Principal Investigator
  3. R21AI139735 (JAIN, NITYA) Jan 16, 2019 - Dec 31, 2021
    Role of innate immune recognition in adaptive T cell development in early life
    Role: Principal Investigator
  4. K22AI116661 (JAIN, NITYA) Mar 15, 2016 - Feb 28, 2018
    Influence of intestinal microbiota on post-natal thymic T cell development
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Philpott J, Kazimierczyk S, Korgaonkar P, Bordt E, Zois J, Vasudevan C, Meng D, Bhatia I, Lu N, Jimena B, Porter C, Cherayil BJ, Jain N. RXRa Regulates the Development of Resident Tissue Macrophages. Immunohorizons. 2022 06 22; 6(6):366-372. PMID: 35732333; PMCID: PMC9316889.
    Citations:    Fields:    Translation:AnimalsCells
  2. Jain N. The early life education of the immune system: Moms, microbes and (missed) opportunities. Gut Microbes. 2020 11 09; 12(1):1824564. PMID: 33043833.
    Citations: 3     Fields:    Translation:HumansAnimals
  3. Ennamorati M, Vasudevan C, Clerkin K, Halvorsen S, Verma S, Ibrahim S, Prosper S, Porter C, Yeliseyev V, Kim M, Gardecki J, Sassi S, Tearney G, Cherayil BJ, Bry L, Seed B, Jain N. Intestinal microbes influence development of thymic lymphocytes in early life. Proc Natl Acad Sci U S A. 2020 02 04; 117(5):2570-2578. PMID: 31964813; PMCID: PMC7007548.
    Citations: 21     Fields:    Translation:HumansAnimalsCells
  4. Miranda-Ribera A, Ennamorati M, Serena G, Cetinbas M, Lan J, Sadreyev RI, Jain N, Fasano A, Fiorentino M. Exploiting the Zonulin Mouse Model to Establish the Role of Primary Impaired Gut Barrier Function on Microbiota Composition and Immune Profiles. Front Immunol. 2019; 10:2233. PMID: 31608059.
    Citations: 13     Fields:    Translation:AnimalsCells
  5. Spidale NA, Sylvia K, Narayan K, Miu B, Frascoli M, Melichar HJ, Zhihao W, Kisielow J, Palin A, Serwold T, Love P, Kobayashi M, Yoshimoto M, Jain N, Kang J. Interleukin-17-Producing ?d T Cells Originate from SOX13+ Progenitors that Are Independent of ?dTCR Signaling. Immunity. 2018 11 20; 49(5):857-872.e5. PMID: 30413363.
    Citations: 23     Fields:    Translation:HumansAnimalsCells
  6. Porter C, Ennamorati M, Jain N. In Vivo Photolabeling of Cells in the Colon to Assess Migratory Potential of Hematopoietic Cells in Neonatal Mice. J Vis Exp. 2018 08 10; (138). PMID: 30148489.
    Citations: 3     Fields:    Translation:HumansAnimals
  7. Jain N, Walker WA. Diet and host-microbial crosstalk in postnatal intestinal immune homeostasis. Nat Rev Gastroenterol Hepatol. 2015 Jan; 12(1):14-25. PMID: 25201040.
    Citations: 39     Fields:    Translation:Humans
  8. Jain N, Miu B, Jiang JK, McKinstry KK, Prince A, Swain SL, Greiner DL, Thomas CJ, Sanderson MJ, Berg LJ, Kang J. CD28 and ITK signals regulate autoreactive T cell trafficking. Nat Med. 2013 Dec; 19(12):1632-7. PMID: 24270545.
    Citations: 24     Fields:    Translation:AnimalsCells
  9. Jain N, Nguyen H, Chambers C, Kang J. Dual function of CTLA-4 in regulatory T cells and conventional T cells to prevent multiorgan autoimmunity. Proc Natl Acad Sci U S A. 2010 Jan 26; 107(4):1524-8. PMID: 20080649.
    Citations: 86     Fields:    Translation:AnimalsCells
  10. Jain N, Nguyen H, Friedline RH, Malhotra N, Brehm M, Koyanagi M, Bix M, Cooper JA, Chambers CA, Kang J. Cutting edge: Dab2 is a FOXP3 target gene required for regulatory T cell function. J Immunol. 2009 Oct 01; 183(7):4192-6. PMID: 19767570; PMCID: PMC2852251.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  11. Bodas M, Jain N, Awasthi A, Martin S, Penke Loka RK, Dandekar D, Mitra D, Saha B. Inhibition of IL-2 induced IL-10 production as a principle of phase-specific immunotherapy. J Immunol. 2006 Oct 01; 177(7):4636-43. PMID: 16982902.
    Citations: 18     Fields:    Translation:AnimalsCells
  12. Awasthi A, Mathur R, Khan A, Joshi BN, Jain N, Sawant S, Boppana R, Mitra D, Saha B. CD40 signaling is impaired in L. major-infected macrophages and is rescued by a p38MAPK activator establishing a host-protective memory T cell response. J Exp Med. 2003 Apr 21; 197(8):1037-43. PMID: 12695487; PMCID: PMC2193877.
    Citations: 34     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.