Pituitary Adenylate Cyclase-Activating Polypeptide
"Pituitary Adenylate Cyclase-Activating Polypeptide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A multi-function neuropeptide that acts throughout the body by elevating intracellular cyclic AMP level via its interaction with PACAP RECEPTORS. Although first isolated from hypothalamic extracts and named for its action on the pituitary, it is widely distributed in the central and peripheral nervous systems. PACAP is important in the control of endocrine and homeostatic processes, such as secretion of pituitary and gut hormones and food intake.
MeSH Number(s)
D12.644.276.860.887
D12.644.400.625
D12.776.467.860.887
D12.776.641.600.887
D12.776.641.650.625
D23.529.850.887
Below are MeSH descriptors whose meaning is more general than "Pituitary Adenylate Cyclase-Activating Polypeptide".
Below are MeSH descriptors whose meaning is more specific than "Pituitary Adenylate Cyclase-Activating Polypeptide".
This graph shows the total number of publications written about "Pituitary Adenylate Cyclase-Activating Polypeptide" by people in Harvard Catalyst Profiles by year, and whether "Pituitary Adenylate Cyclase-Activating Polypeptide" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1992 | 0 | 1 | 1 |
| 1995 | 0 | 4 | 4 |
| 1996 | 0 | 2 | 2 |
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 2 | 2 |
| 1999 | 0 | 2 | 2 |
| 2000 | 0 | 2 | 2 |
| 2001 | 0 | 3 | 3 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2008 | 1 | 1 | 2 |
| 2009 | 2 | 2 | 4 |
| 2011 | 1 | 1 | 2 |
| 2012 | 2 | 0 | 2 |
| 2013 | 1 | 1 | 2 |
| 2014 | 1 | 3 | 4 |
| 2015 | 3 | 0 | 3 |
| 2016 | 5 | 1 | 6 |
| 2018 | 2 | 2 | 4 |
| 2019 | 2 | 0 | 2 |
| 2020 | 2 | 1 | 3 |
| 2021 | 1 | 0 | 1 |
Below are the most recent publications written about "Pituitary Adenylate Cyclase-Activating Polypeptide" by people in Profiles.
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The Role of Mediobasal Hypothalamic PACAP in the Control of Body Weight and Metabolism. Endocrinology. 2021 04 01; 162(4).
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A brainstem peptide system activated at birth protects postnatal breathing. Nature. 2021 01; 589(7842):426-430.
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Lipocalin-type prostaglandin D synthase regulates light-induced phase advance of the central circadian rhythm in mice. Commun Biol. 2020 10 08; 3(1):557.
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Neurons that regulate mouse torpor. Nature. 2020 07; 583(7814):115-121.
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Circulating PACAP peptide and PAC1R genotype as possible transdiagnostic biomarkers for anxiety disorders in women: a preliminary study. Neuropsychopharmacology. 2020 06; 45(7):1125-1133.
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Role of the PACAP system of the extended amygdala in the acoustic startle response in rats. Neuropharmacology. 2019 12 01; 160:107761.
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Glycosaminoglycans Induce Amyloid Self-Assembly of a Peptide Hormone by Concerted Secondary and Quaternary Conformational Transitions. Biochemistry. 2019 03 05; 58(9):1214-1225.
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PACAP increases Arc/Arg 3.1 expression within the extended amygdala after fear conditioning in rats. Neurobiol Learn Mem. 2019 01; 157:24-34.
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Molecular, spatial, and functional single-cell profiling of the hypothalamic preoptic region. Science. 2018 11 16; 362(6416).
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Current understanding of meningeal and cerebral vascular function underlying migraine headache. Cephalalgia. 2019 11; 39(13):1606-1622.