Ornithine-Oxo-Acid Transaminase

"Ornithine-Oxo-Acid Transaminase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A pyridoxal phosphate enzyme that catalyzes the formation of glutamate gamma-semialdehyde and an L-amino acid from L-ornithine and a 2-keto-acid. EC 2.6.1.13.

Descriptor ID

D009953

MeSH Number(s)

D08.811.913.477.700.700

Concept/Terms

Ornithine-Oxo-Acid Transaminase

Below are MeSH descriptors whose meaning is more general than "Ornithine-Oxo-Acid Transaminase".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Transferases [D08.811.913]
Nitrogenous Group Transferases [D08.811.913.477]
Transaminases [D08.811.913.477.700]
Ornithine-Oxo-Acid Transaminase [D08.811.913.477.700.700]

Below are MeSH descriptors whose meaning is related to "Ornithine-Oxo-Acid Transaminase".

Below are MeSH descriptors whose meaning is more specific than "Ornithine-Oxo-Acid Transaminase".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Ornithine-Oxo-Acid Transaminase" by people in Harvard Catalyst Profiles by year, and whether "Ornithine-Oxo-Acid Transaminase" was a major or minor topic of these publication.

Bar chart showing 6 publications over 6 distinct years, with a maximum of 1 publications in 1996 and 2005 and 2012 and 2015 and 2021 and 2022

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	1	0	1
2005	1	0	1
2012	0	1	1
2015	1	0	1
2021	1	0	1
2022	0	1	1

Below are the most recent publications written about "Ornithine-Oxo-Acid Transaminase" by people in Profiles.

Rational Design, Synthesis, and Mechanism of (3S,4R)-3-Amino-4-(difluoromethyl)cyclopent-1-ene-1-carboxylic Acid: Employing a Second-Deprotonation Strategy for Selectivity of Human Ornithine Aminotransferase over GABA Aminotransferase. J Am Chem Soc. 2022 03 30; 144(12):5629-5642.

View in: PubMed
Turnover and Inactivation Mechanisms for (S)-3-Amino-4,4-difluorocyclopent-1-enecarboxylic Acid, a Selective Mechanism-Based Inactivator of Human Ornithine Aminotransferase. J Am Chem Soc. 2021 06 16; 143(23):8689-8703.

View in: PubMed
Reversal of cystoid macular edema in gyrate atrophy patients. Ophthalmic Genet. 2017 12; 38(6):549-554.

View in: PubMed
Recurrent De Novo Mutations Affecting Residue Arg138 of Pyrroline-5-Carboxylate Synthase Cause a Progeroid Form of Autosomal-Dominant Cutis Laxa. Am J Hum Genet. 2015 Sep 03; 97(3):483-92.

View in: PubMed
A blue native polyacrylamide gel electrophoretic technology to probe the functional proteomics mediating nitrogen homeostasis in Pseudomonas fluorescens. J Microbiol Methods. 2012 Sep; 90(3):206-10.

View in: PubMed
Identification of novel androgen receptor target genes in prostate cancer. Mol Cancer. 2007 Jun 06; 6:39.

View in: PubMed
Ornithine aminotransferase deficiency: diagnostic difficulties in neonatal presentation. J Inherit Metab Dis. 2005; 28(5):673-9.

View in: PubMed
GABA and the ornithine delta-aminotransferase gene in vigabatrin-associated visual field defects. Seizure. 2001 Oct; 10(7):505-7.

View in: PubMed
Adenovirus-mediated gene transfer of ornithine aminotransferase in cultured human retinal pigment epithelium. Invest Ophthalmol Vis Sci. 1996 Apr; 37(5):766-74.

View in: PubMed
Construction of two YAC contigs in human Xp11.23-p11.22, one encompassing the loci OATL1, GATA, TFE3, and SYP, the other linking DXS255 to DXS146. Genomics. 1995 Sep 20; 29(2):496-502.

View in: PubMed

Related Networks

People

Explore

Similar Concepts

Top Journals

Am J Hum Genet
Genomics
J Am Chem Soc
J Inherit Metab Dis
Invest Ophthalmol Vis Sci
Hum Mutat
Hum Genet
DNA
Cytogenet Cell Genet
Clin Chim Acta