Ornithine-Oxo-Acid Transaminase

"Ornithine-Oxo-Acid Transaminase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A pyridoxal phosphate enzyme that catalyzes the formation of glutamate gamma-semialdehyde and an L-amino acid from L-ornithine and a 2-keto-acid. EC 2.6.1.13.

Descriptor ID

D009953

MeSH Number(s)

D08.811.913.477.700.700

Concept/Terms

Ornithine-Oxo-Acid Transaminase

Below are MeSH descriptors whose meaning is more general than "Ornithine-Oxo-Acid Transaminase".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Transferases [D08.811.913]
Nitrogenous Group Transferases [D08.811.913.477]
Transaminases [D08.811.913.477.700]
Ornithine-Oxo-Acid Transaminase [D08.811.913.477.700.700]

Below are MeSH descriptors whose meaning is related to "Ornithine-Oxo-Acid Transaminase".

Below are MeSH descriptors whose meaning is more specific than "Ornithine-Oxo-Acid Transaminase".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Ornithine-Oxo-Acid Transaminase" by people in Harvard Catalyst Profiles by year, and whether "Ornithine-Oxo-Acid Transaminase" was a major or minor topic of these publication.

Below are the most recent publications written about "Ornithine-Oxo-Acid Transaminase" by people in Profiles.

Foveoschisis associated with gyrate atrophy in ornithine aminotransferase deficiency: A case report. Photodiagnosis Photodyn Ther. 2023 Jun; 42:103618.

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Ornithine aminotransferase supports polyamine synthesis in pancreatic cancer. Nature. 2023 04; 616(7956):339-347.

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Rational Design, Synthesis, and Mechanism of (3S,4R)-3-Amino-4-(difluoromethyl)cyclopent-1-ene-1-carboxylic Acid: Employing a Second-Deprotonation Strategy for Selectivity of Human Ornithine Aminotransferase over GABA Aminotransferase. J Am Chem Soc. 2022 03 30; 144(12):5629-5642.

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Turnover and Inactivation Mechanisms for (S)-3-Amino-4,4-difluorocyclopent-1-enecarboxylic Acid, a Selective Mechanism-Based Inactivator of Human Ornithine Aminotransferase. J Am Chem Soc. 2021 06 16; 143(23):8689-8703.

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Reversal of cystoid macular edema in gyrate atrophy patients. Ophthalmic Genet. 2017 12; 38(6):549-554.

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Recurrent De Novo Mutations Affecting Residue Arg138 of Pyrroline-5-Carboxylate Synthase Cause a Progeroid Form of Autosomal-Dominant Cutis Laxa. Am J Hum Genet. 2015 Sep 03; 97(3):483-92.

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A blue native polyacrylamide gel electrophoretic technology to probe the functional proteomics mediating nitrogen homeostasis in Pseudomonas fluorescens. J Microbiol Methods. 2012 Sep; 90(3):206-10.

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Identification of novel androgen receptor target genes in prostate cancer. Mol Cancer. 2007 Jun 06; 6:39.

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Ornithine aminotransferase deficiency: diagnostic difficulties in neonatal presentation. J Inherit Metab Dis. 2005; 28(5):673-9.

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GABA and the ornithine delta-aminotransferase gene in vigabatrin-associated visual field defects. Seizure. 2001 Oct; 10(7):505-7.

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