Contact, publication, and social network information about Harvard faculty and fellows. Harvard Catalyst Profiles
Keywords
Last Name
Institution

profileNucleic Acid Denaturation

"Nucleic Acid Denaturation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

expand / collapse MeSH information
Disruption of the secondary structure of nucleic acids by heat, extreme pH or chemical treatment. Double strand DNA is "melted" by dissociation of the non-covalent hydrogen bonds and hydrophobic interactions. Denatured DNA appears to be a single-stranded flexible structure. The effects of denaturation on RNA are similar though less pronounced and largely reversible.


expand / collapse publications
This graph shows the total number of publications written about "Nucleic Acid Denaturation" by people in Harvard Catalyst Profiles by year, and whether "Nucleic Acid Denaturation" was a major or minor topic of these publication.
Bar chart showing 82 publications over 30 distinct years, with a maximum of 10 publications in 2009
To see the data from this visualization as text, click here.