Leukotriene B4

"Leukotriene B4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The major metabolite in neutrophil polymorphonuclear leukocytes. It stimulates polymorphonuclear cell function (degranulation, formation of oxygen-centered free radicals, arachidonic acid release, and metabolism). (From Dictionary of Prostaglandins and Related Compounds, 1990)

Descriptor ID

D007975

MeSH Number(s)

D10.251.355.255.100.450.411

D23.469.050.175.450.415

Concept/Terms

Leukotriene B4

Leukotrienes B

5,12-diHETE

Below are MeSH descriptors whose meaning is more general than "Leukotriene B4".

Chemicals and Drugs [D]
Lipids [D10]
Fatty Acids [D10.251]
Fatty Acids, Unsaturated [D10.251.355]
Eicosanoids [D10.251.355.255]
Arachidonic Acids [D10.251.355.255.100]
Leukotrienes [D10.251.355.255.100.450]
Leukotriene B4 [D10.251.355.255.100.450.411]
Biological Factors [D23]
Inflammation Mediators [D23.469]
Autacoids [D23.469.050]
Eicosanoids [D23.469.050.175]
Leukotrienes [D23.469.050.175.450]
Leukotriene B4 [D23.469.050.175.450.415]

Below are MeSH descriptors whose meaning is related to "Leukotriene B4".

Below are MeSH descriptors whose meaning is more specific than "Leukotriene B4".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Leukotriene B4" by people in Harvard Catalyst Profiles by year, and whether "Leukotriene B4" was a major or minor topic of these publication.

Bar chart showing 126 publications over 31 distinct years, with a maximum of 7 publications in 2000 and 2001 and 2003 and 2011 and 2014

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1993	1	4	5
1994	1	0	1
1995	1	2	3
1996	2	2	4
1997	1	1	2
1998	0	3	3
1999	2	3	5
2000	2	5	7
2001	2	5	7
2002	0	3	3
2003	3	4	7
2004	1	3	4
2005	2	3	5
2006	4	1	5
2007	0	4	4
2008	0	2	2
2009	1	2	3
2010	3	3	6
2011	2	5	7
2012	1	5	6
2013	1	3	4
2014	4	3	7
2015	1	1	2
2016	1	1	2
2017	3	3	6
2018	4	2	6
2019	0	2	2
2020	1	2	3
2021	1	2	3
2022	0	1	1
2023	1	0	1

Below are the most recent publications written about "Leukotriene B4" by people in Profiles.

ACKR3 promotes CXCL12/CXCR4-mediated cell-to-cell-induced lymphoma migration through LTB4 production. Front Immunol. 2022; 13:1067885.

View in: PubMed
Isoflurane attenuates sepsis-associated lung injury. Biochem Biophys Res Commun. 2022 04 09; 599:127-133.

View in: PubMed
Neutrophils self-limit swarming to contain bacterial growth in vivo. Science. 2021 06 18; 372(6548).

View in: PubMed
Dual inhibition of complement component 5 and leukotriene B4 by topical rVA576 in atopic keratoconjunctivis: TRACKER phase 1 clinical trial results. Orphanet J Rare Dis. 2021 06 11; 16(1):270.

View in: PubMed
Regression of human coronary artery plaque is associated with a high ratio of (18-hydroxy-eicosapentaenoic acid + resolvin E1) to leukotriene B4. FASEB J. 2021 04; 35(4):e21448.

View in: PubMed
Resolvin E1 Reduces Leukotriene B4-Induced Intracellular Calcium Increase and Mucin Secretion in Rat Conjunctival Goblet Cells. Am J Pathol. 2020 09; 190(9):1823-1832.

View in: PubMed
The role of propofol hydroxyl group in 5-lipoxygenase recognition. Biochem Biophys Res Commun. 2020 05 14; 525(4):909-914.

View in: PubMed
Redundant and Cooperative Roles for Yersinia pestis Yop Effectors in the Inhibition of Human Neutrophil Exocytic Responses Revealed by Gain-of-Function Approach. Infect Immun. 2020 02 20; 88(3).

View in: PubMed
Super-Low Dose Lipopolysaccharide Dysregulates Neutrophil Migratory Decision-Making. Front Immunol. 2019; 10:359.

View in: PubMed
A noncanonical role for the engulfment gene ELMO1 in neutrophils that promotes inflammatory arthritis. Nat Immunol. 2019 02; 20(2):141-151.

View in: PubMed

Related Networks

People

Explore

Similar Concepts

Top Journals

J Immunol
J Biol Chem
J Exp Med
Proc Natl Acad Sci U S A
Surgery
Am Rev Respir Dis
Arthritis Rheum
Nat Immunol
FASEB J
Adv Prostaglandin Thromboxane Leukot Res