Leukotriene B4

"Leukotriene B4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The major metabolite in neutrophil polymorphonuclear leukocytes. It stimulates polymorphonuclear cell function (degranulation, formation of oxygen-centered free radicals, arachidonic acid release, and metabolism). (From Dictionary of Prostaglandins and Related Compounds, 1990)

Descriptor ID

D007975

MeSH Number(s)

D10.251.355.255.100.450.411

D23.469.050.175.450.415

Concept/Terms

Leukotriene B4

Leukotrienes B

5,12-diHETE

Below are MeSH descriptors whose meaning is more general than "Leukotriene B4".

Chemicals and Drugs [D]
Lipids [D10]
Fatty Acids [D10.251]
Fatty Acids, Unsaturated [D10.251.355]
Eicosanoids [D10.251.355.255]
Arachidonic Acids [D10.251.355.255.100]
Leukotrienes [D10.251.355.255.100.450]
Leukotriene B4 [D10.251.355.255.100.450.411]
Biological Factors [D23]
Inflammation Mediators [D23.469]
Autacoids [D23.469.050]
Eicosanoids [D23.469.050.175]
Leukotrienes [D23.469.050.175.450]
Leukotriene B4 [D23.469.050.175.450.415]

Below are MeSH descriptors whose meaning is related to "Leukotriene B4".

Below are MeSH descriptors whose meaning is more specific than "Leukotriene B4".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Leukotriene B4" by people in Harvard Catalyst Profiles by year, and whether "Leukotriene B4" was a major or minor topic of these publication.

Bar chart showing 143 publications over 31 distinct years, with a maximum of 11 publications in 1991 and 1992

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1991	4	7	11
1992	6	5	11
1993	1	4	5
1994	1	0	1
1995	1	2	3
1996	2	2	4
1997	1	1	2
1998	0	3	3
1999	2	3	5
2000	2	5	7
2001	1	5	6
2002	0	3	3
2003	3	4	7
2004	1	3	4
2005	2	3	5
2006	4	1	5
2007	0	4	4
2008	1	2	3
2009	1	2	3
2010	3	1	4
2011	2	5	7
2012	2	5	7
2013	1	3	4
2014	3	3	6
2015	1	2	3
2016	1	1	2
2017	2	3	5
2018	4	2	6
2019	0	1	1
2020	1	2	3
2021	1	2	3

Below are the most recent publications written about "Leukotriene B4" by people in Profiles.

Neutrophils self-limit swarming to contain bacterial growth in vivo. Science. 2021 06 18; 372(6548).

View in: PubMed
Dual inhibition of complement component 5 and leukotriene B4 by topical rVA576 in atopic keratoconjunctivis: TRACKER phase 1 clinical trial results. Orphanet J Rare Dis. 2021 06 11; 16(1):270.

View in: PubMed
Regression of human coronary artery plaque is associated with a high ratio of (18-hydroxy-eicosapentaenoic acid + resolvin E1) to leukotriene B4. FASEB J. 2021 04; 35(4):e21448.

View in: PubMed
Resolvin E1 Reduces Leukotriene B4-Induced Intracellular Calcium Increase and Mucin Secretion in Rat Conjunctival Goblet Cells. Am J Pathol. 2020 09; 190(9):1823-1832.

View in: PubMed
The role of propofol hydroxyl group in 5-lipoxygenase recognition. Biochem Biophys Res Commun. 2020 05 14; 525(4):909-914.

View in: PubMed
Redundant and Cooperative Roles for Yersinia pestis Yop Effectors in the Inhibition of Human Neutrophil Exocytic Responses Revealed by Gain-of-Function Approach. Infect Immun. 2020 02 20; 88(3).

View in: PubMed
Super-Low Dose Lipopolysaccharide Dysregulates Neutrophil Migratory Decision-Making. Front Immunol. 2019; 10:359.

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Lipid Mediators, M2 Macrophages, and Pathological Neovascularization. Trends Mol Med. 2018 12; 24(12):977-978.

View in: PubMed
A subset of five human mitochondrial formyl peptides mimics bacterial peptides and functionally deactivates human neutrophils. J Trauma Acute Care Surg. 2018 11; 85(5):936-943.

View in: PubMed
Leukotriene B4 promotes neovascularization and macrophage recruitment in murine wet-type AMD models. JCI Insight. 2018 09 20; 3(18).

View in: PubMed

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