GTP-Binding Protein alpha Subunits, G12-G13
"GTP-Binding Protein alpha Subunits, G12-G13" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ubiquitously expressed family of heterotrimeric GTP-binding protein alpha subunits that signal through interactions with a variety of second messengers as GTPASE-ACTIVATING PROTEINS; GUANINE NUCLEOTIDE EXCHANGE FACTORS; and HEAT SHOCK PROTEINS. The G12-G13 part of the name is also spelled G12/G13.
MeSH Number(s)
D08.811.277.040.330.300.200.100.100
D12.644.360.375.100.100
D12.776.157.325.332.100.100
D12.776.476.375.100.100
D12.776.543.325.100.100
Concept/Terms
GTP-Binding Protein alpha Subunits, G12-G13- GTP-Binding Protein alpha Subunits, G12-G13
- GTP Binding Protein alpha Subunits, G12 G13
- G-Protein, G12-G13 alpha Subunits
- G Protein, G12 G13 alpha Subunits
- G-Protein, G12-G13 alpha Family
- G Protein, G12 G13 alpha Family
GTP-Binding Protein alpha Subunit, G13- GTP-Binding Protein alpha Subunit, G13
- GTP Binding Protein alpha Subunit, G13
- G(13) Protein
- Galpha13 Protein
- G13 G-Protein
- G-Protein, G13
- G13 G Protein
- G13 Protein
- G alpha13 Protein
- alpha13 Protein, G
- G-Protein, G13 Subunit
- G Protein, G13 Subunit
- G13 Subunit G-Protein
- Subunit G-Protein, G13
GTP-Binding Protein alpha Subunit, G12- GTP-Binding Protein alpha Subunit, G12
- GTP Binding Protein alpha Subunit, G12
- Galpha12 Protein
- G12 alpha Protein
- alpha Protein, G12
- G12 Protein
- Protein, G12
- G alpha12 Protein
- alpha12 Protein, G
- G-Protein, G12 Subunit
- G Protein, G12 Subunit
- G12 Subunit G-Protein
- Subunit G-Protein, G12
Below are MeSH descriptors whose meaning is more general than "GTP-Binding Protein alpha Subunits, G12-G13".
Below are MeSH descriptors whose meaning is more specific than "GTP-Binding Protein alpha Subunits, G12-G13".
This graph shows the total number of publications written about "GTP-Binding Protein alpha Subunits, G12-G13" by people in Harvard Catalyst Profiles by year, and whether "GTP-Binding Protein alpha Subunits, G12-G13" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 2 | 2 |
| 2002 | 0 | 2 | 2 |
| 2003 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2006 | 1 | 1 | 2 |
| 2007 | 2 | 0 | 2 |
| 2008 | 1 | 0 | 1 |
| 2009 | 2 | 1 | 3 |
| 2010 | 2 | 0 | 2 |
| 2011 | 1 | 0 | 1 |
| 2012 | 2 | 0 | 2 |
| 2013 | 2 | 0 | 2 |
| 2014 | 1 | 1 | 2 |
| 2015 | 2 | 0 | 2 |
| 2016 | 2 | 0 | 2 |
| 2018 | 0 | 1 | 1 |
| 2020 | 1 | 1 | 2 |
| 2021 | 0 | 1 | 1 |
Below are the most recent publications written about "GTP-Binding Protein alpha Subunits, G12-G13" by people in Profiles.
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The adaptive immune system is a major driver of selection for tumor suppressor gene inactivation. Science. 2021 Sep 17; 373(6561):1327-1335.
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Trastuzumab-induced upregulation of a protein set in extracellular vesicles emitted by ErbB2-positive breast cancer cells correlates with their trastuzumab sensitivity. Breast Cancer Res. 2020 10 06; 22(1):105.
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Heterotrimeric Ga12/13 proteins in kidney injury and disease. Am J Physiol Renal Physiol. 2020 03 01; 318(3):F660-F672.
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The Ga12/13-coupled receptor LPA4 limits proper adipose tissue expansion and remodeling in diet-induced obesity. JCI Insight. 2018 12 20; 3(24).
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A Rapid Method for Directed Gene Knockout for Screening in G0 Zebrafish. Dev Cell. 2018 07 02; 46(1):112-125.e4.
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GPR56/ADGRG1 regulates development and maintenance of peripheral myelin. J Exp Med. 2018 03 05; 215(3):941-961.
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FZD10-Ga13 signalling axis points to a role of FZD10 in CNS angiogenesis. Cell Signal. 2017 04; 32:93-103.
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Ga13 Switch Region 2 Relieves Talin Autoinhibition to Activate aIIbß3 Integrin. J Biol Chem. 2016 Dec 23; 291(52):26598-26612.
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Ga12 is required for renal cystogenesis induced by Pkd1 inactivation. J Cell Sci. 2016 10 01; 129(19):3675-3684.
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WNT Stimulation Dissociates a Frizzled 4 Inactive-State Complex with Ga12/13. Mol Pharmacol. 2016 10; 90(4):447-59.