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Fas-Associated Death Domain Protein

"Fas-Associated Death Domain Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

A signal-transducing adaptor protein that associates with TNF RECEPTOR complexes. It contains a death effector domain that can interact with death effector domains found on INITIATOR CASPASES such as CASPASE 8 and CASPASE 10. Activation of CASPASES via interaction with this protein plays a role in the signaling cascade that leads to APOPTOSIS.


This graph shows the total number of publications written about "Fas-Associated Death Domain Protein" by people in Harvard Catalyst Profiles by year, and whether "Fas-Associated Death Domain Protein" was a major or minor topic of these publication.
Bar chart showing 27 publications over 15 distinct years, with a maximum of 3 publications in 2006 and 2016 and 2017
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.