"Crossing Over, Genetic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The reciprocal exchange of segments at corresponding positions along pairs of homologous CHROMOSOMES by symmetrical breakage and crosswise rejoining forming cross-over sites (HOLLIDAY JUNCTIONS) that are resolved during CHROMOSOME SEGREGATION. Crossing-over typically occurs during MEIOSIS but it may also occur in the absence of meiosis, for example, with bacterial chromosomes, organelle chromosomes, or somatic cell nuclear chromosomes.
Concept/Terms
Crossing Over, Genetic- Crossing Over, Genetic
- Genetic Crossing Over
- Crossing-Over, Genetic
- Genetic Crossing-Over
- Crossing Over
- Crossing Overs
Below are MeSH descriptors whose meaning is more general than "Crossing Over, Genetic".
Below are MeSH descriptors whose meaning is more specific than "Crossing Over, Genetic".
This graph shows the total number of publications written about "Crossing Over, Genetic" by people in Harvard Catalyst Profiles by year, and whether "Crossing Over, Genetic" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1992 | 0 | 4 | 4 |
| 1993 | 0 | 2 | 2 |
| 1994 | 3 | 2 | 5 |
| 1995 | 1 | 4 | 5 |
| 1997 | 1 | 1 | 2 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 3 | 3 |
| 2001 | 0 | 2 | 2 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 2 | 2 |
| 2004 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 1 | 2 |
| 2008 | 1 | 1 | 2 |
| 2009 | 2 | 2 | 4 |
| 2011 | 1 | 0 | 1 |
| 2012 | 0 | 3 | 3 |
| 2013 | 1 | 3 | 4 |
| 2014 | 2 | 0 | 2 |
| 2015 | 1 | 1 | 2 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2020 | 1 | 2 | 3 |
| 2021 | 0 | 1 | 1 |
Below are the most recent publications written about "Crossing Over, Genetic" by people in Profiles.
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Implications of mosaicism in variant interpretation: A case of a de novo homozygous NF1 variant. Eur J Med Genet. 2021 Jul; 64(7):104236.
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HIM-17 regulates the position of recombination events and GSP-1/2 localization to establish short arm identity on bivalents in meiosis. Proc Natl Acad Sci U S A. 2021 04 27; 118(17).
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Sequence analysis in Bos taurus reveals pervasiveness of X-Y arms races in mammalian lineages. Genome Res. 2020 12; 30(12):1716-1726.
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Insights into variation in meiosis from 31,228 human sperm genomes. Nature. 2020 07; 583(7815):259-264.
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Environmentally-relevant exposure to diethylhexyl phthalate (DEHP) alters regulation of double-strand break formation and crossover designation leading to germline dysfunction in Caenorhabditis elegans. PLoS Genet. 2020 01; 16(1):e1008529.
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Meiotic MCM Proteins Promote and Inhibit Crossovers During Meiotic Recombination. Genetics. 2019 06; 212(2):461-468.
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Zipping and Unzipping: Protein Modifications Regulating Synaptonemal Complex Dynamics. Trends Genet. 2018 03; 34(3):232-245.
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The MAP kinase pathway coordinates crossover designation with disassembly of synaptonemal complex proteins during meiosis. Elife. 2016 Feb 27; 5:e12039.
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Maternal Modifiers and Parent-of-Origin Bias of the Autism-Associated 16p11.2 CNV. Am J Hum Genet. 2016 Jan 07; 98(1):45-57.
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The kinetochore prevents centromere-proximal crossover recombination during meiosis. Elife. 2015 Dec 14; 4.